scholarly journals Effective vaccine allocation strategies, balancing economy with infection control against COVID-19 in Japan

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257107
Author(s):  
Satoshi Sunohara ◽  
Toshiaki Asakura ◽  
Takashi Kimura ◽  
Shun Ozawa ◽  
Satoshi Oshima ◽  
...  
Keyword(s):  
Infection Control ◽  
Linear Relationship ◽  
Vaccination Strategy ◽  
Economic Loss ◽  
Economic Losses ◽  
Effective Vaccine ◽  
Remote Work ◽  
Economic Activities ◽  
Sufficient Reduction ◽  
Allocation Strategies

Due to COVID-19, many countries including Japan have implemented a suspension of economic activities for infection control. It has contributed to reduce the transmission of COVID-19 but caused severe economic losses. Today, several promising vaccines have been developed and are already being distributed in some countries. Therefore, we evaluated various vaccine and intensive countermeasure strategies with constraint of economic loss using SEIR model to obtain knowledge of how to balance economy with infection control in Japan. Our main results were that the vaccination strategy that prioritized younger generation was better in terms of deaths when a linear relationship between lockdown intensity and acceptable economic loss was assumed. On the other hand, when a non-linearity relationship was introduced, implying that the strong lockdown with small economic loss was possible, the old first strategies were best in the settings of small basic reproduction number. These results indicated a high potential of remote work when prioritizing vaccination for the old generation. When focusing on only the old first strategies as the Japanese government has decided to do, the strategy vaccinating the young next to the old was superior to the others when a non-linear relationship was assumed due to sufficient reduction of contact with small economic loss.

scholarly journals Effective vaccine allocation strategies, balancing economy with infection control against COVID-19 in Japan

2021 ◽  
Author(s):  
Satoshi Sunohara ◽  
Toshiaki Asakura ◽  
Takashi Kimura ◽  
Shun Ozawa ◽  
Satoshi Oshima ◽  
...  
Keyword(s):  
Infection Control ◽  
Old Age ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Vaccination Strategy ◽  
Economic Loss ◽  
The Other ◽  
Economic Losses ◽  
Age Group ◽  
The Basic Reproduction Number

AbstractDue to COVID-19, many countries including Japan have implemented a suspension of economic activities for infection control. It has contributed to reduce the transmission of COVID-19 but caused severe economic losses. Today, several promising vaccines have been developed and are already being distributed in some countries. Therefore, we evaluated various vaccine and intensive countermeasure strategies with constraint of economic loss using SEIR model to obtain knowledge of how to balance economy with infection control in Japan. Our main result is that the vaccination strategy that prioritizes younger generation outperformed the other strategies in terms of deaths. On the other hand, when we focused on strategies that prioritize older generation, as Japan has decided to do, the optimal vaccination strategy was determined by the basic reproduction number and acceptable economic loss. The strategy vaccinating the young next to the old age group was the best when acceptable economic loss was high, or the basic reproduction number was low. Alternatively, the strategy vaccinating the middle next to the old age group was superior to the others with a moderate acceptable economic loss and the high basic reproduction number setting.

scholarly journals Seismic Indirect Economic Loss Assessment and Recovery Evaluation Using Night-time Light Images – Application for Wenchuan Earthquake

2018 ◽  
Author(s):  
Jianfei Wang ◽  
Jingfa Zhang ◽  
Lixia Gong ◽  
Qiang Li ◽  
Dan Zhou
Keyword(s):  
Wenchuan Earthquake ◽  
Light Attenuation ◽  
National Level ◽  
Economic Loss ◽  
Economic Losses ◽  
Economic Activities ◽  
Night Time ◽  
Regional Economic ◽  
Disaster Area ◽  
Indirect Economic Loss

Abstract. Seismic indirect economic loss not only has a major impact on regional economic recovery policies, but also related to the economic assistance at the national level. Due to the Cross-regional economic activities and the difficulty of obtaining data, it's difficult that the indirect economic loss survey covers all economic activities. However, night-time light in an area can reflect the economic activity of the region. This paper focuses on the indirect economic losses caused by the Wenchuan earthquake in 2008 and evaluated the progress of restoration and reconstruction based on night-time light Images. First, the functional relationship between GDP and night-time light parameters was established based on the pre-earthquake data. Next, the indirect loss of the earthquake was evaluated by the night-time light attenuation in the disaster area after the earthquake. Then, the capacity recovery, which is characterized by the brightness recovery process of the light area, was evaluated. Lastly, the process of light expansion in the disaster area was analyzed to evaluate the economic expansion speed and efficiency.

scholarly journals Indirect seismic economic loss assessment and recovery evaluation using nighttime light images – application for Wenchuan earthquake

2018 ◽  
Vol 18 (12) ◽  
pp. 3253-3266 ◽  
Author(s):  
Jianfei Wang ◽  
Jingfa Zhang ◽  
Lixia Gong ◽  
Qiang Li ◽  
Dan Zhou
Keyword(s):  
Wenchuan Earthquake ◽  
Light Attenuation ◽  
National Level ◽  
Economic Loss ◽  
Economic Losses ◽  
Economic Activities ◽  
Loss Assessment ◽  
Regional Economic ◽  
Disaster Area ◽  
Nighttime Light

Abstract. Indirect seismic economic loss not only impacts regional economic recovery policies but is also related to economic assistance at the national level. Due to cross-regional economic activities and the difficulty of obtaining data, it is difficult for the indirect economic loss survey to cover all economic activities. However, nighttime light in an area can reflect the economic activity of the region. This article focuses on the indirect economic losses caused by the 2008 Wenchuan earthquake and evaluation of the progress of restoration and reconstruction based on nighttime light images. First, the functional relationship between GDP and nighttime light parameters is established based on pre-earthquake data. Next, the indirect loss of the earthquake is evaluated by the nighttime light attenuation in the disaster area after the earthquake. Then, the capacity recovery, which is characterized by the brightness recovery process of the light area, is evaluated. Lastly, the process of light expansion in the disaster area is analyzed to evaluate the speed and efficiency of economic expansion.

Fertiliser evenness - losses and costs: A study on the economic benefits of uniform applications of fertiliser

1999 ◽  
pp. 215-220 ◽  
Author(s):  
R. Horrell ◽  
A.K. Metherell ◽  
S. Ford ◽  
C. Doscher
Keyword(s):  
Crop Yields ◽  
Cumulative Effect ◽  
Economic Loss ◽  
Economic Benefits ◽  
Significant Loss ◽  
Economic Losses ◽  
Financial Return ◽  
Spread Pattern ◽  
Fertiliser Application ◽  
Seed Crops

Over two million tonnes of fertiliser are applied to New Zealand pastures and crops annually and there is an increasing desire by farmers to ensure that the best possible economic return is gained from this investment. Spreading distribution measurements undertaken by Lincoln Ventures Ltd (LVL) have identified large variations in the evenness of fertiliser application by spreading machines which could lead to a failure to achieve optimum potential in some crop yields and to significant associated economic losses. To quantify these losses, a study was undertaken to calculate the effect of uneven fertiliser application on crop yield. From LVL's spreader database, spread patterns from many machines were categorised by spread pattern type and by coefficient of variation (CV). These patterns were then used to calculate yield losses when they were combined with the response data from five representative cropping and pastoral situations. Nitrogen fertiliser on ryegrass seed crops shows significant production losses at a spread pattern CV between 30% and 40%. For P and S on pasture, the cumulative effect of uneven spreading accrues, until there is significant economic loss occurring by year 3 for both the Waikato dairy and Southland sheep and beef systems at CV values between 30% and 40%. For nitrogen on pasture, significant loss in a dairy system occurs at a CV of approximately 40% whereas for a sheep and beef system it is at a CV of 50%, where the financial return from nitrogen application has been calculated at the average gross revenue of the farming system. The conclusion of this study is that the current Spreadmark standards are a satisfactory basis for defining the evenness requirements of fertiliser applications in most circumstances. On the basis of Spreadmark testing to date, more than 50% of the national commercial spreading fleet fails to meet the standard for nitrogenous fertilisers and 40% fails to meet the standard for phosphatic fertilisers.Keywords: aerial spreading, crop response, economic loss, fertiliser, ground spreading, striping, uneven application, uneven spreading, yield loss

THE MAIN DIRECTIONS OF ECONOMIC SUPPORT OF THE REGIONAL SECURITY SYSTEM OF THE POPULATION

2020 ◽  
Vol 1 (11) ◽  
pp. 133-140
Author(s):  
E. V. DMITRIEVA ◽  
Keyword(s):  
Crisis Management ◽  
Security System ◽  
Regional Security ◽  
Economic Losses ◽  
Economic Damage ◽  
Economic Activities ◽  
The Sustainable Development ◽  
Economic Support ◽  
The Impact ◽  
Crisis Situations

The article considers topical issues of economic support for the development of the regional security system of the population against various risks. The dependence of the impact of the scale of crisis situations on economic activities in the constituent entities of the Russian Federation, which become a serious barrier to the sustainable development of the regions of the country, was investigated. The increasing importance of risks of economic losses from accidents and disasters at potentially dangerous facilities as a result of the complex influence of natural, manmade and fire factors has been established. An analysis was carried out and proposals were developed to implement the key tasks of the state in the field of ensuring the protection of the population and territories of the country from disasters in order to ensure the stability of the economy. The organizational structure, division of tasks and functions between officials, crisis management structures and responding units were analyzed, taking into account the reduction in current financial costs. On the basis of a study of the peculiarities of the regions of the country, recommendations were formed to fulfill the necessary tasks by the anti-crisis management bodies in the field of reducing economic damage on the basis of preventing crisis situations and ensuring fire safety. It is proposed to organize the practical application of a complex automated security system based on modern developments with the application of improving the qualities and efficiency of anti-crisis management processes in order to increase economic efficiency. Initial data were formed to reduce potential threats of a natural, man-made, fire and other nature in the regions using financial and economic mechanisms. It is proposed to implement a set of priority measures to further improve and increase the potential of economic support for the anti-crisis management system. The materials of the article can be used in planning the main directions of the development of the regional population security system and the implementation of socio-economic development programs.

scholarly journals Quantification of PV Power and Economic Losses Due to Soiling in Qatar

2021 ◽  
Vol 13 (6) ◽  
pp. 3364
Author(s):  
Amr Zeedan ◽  
Abdulaziz Barakeh ◽  
Khaled Al-Fakhroo ◽  
Farid Touati ◽  
Antonio S. P. Gonzales
Keyword(s):  
Output Power ◽  
Power Plants ◽  
Economic Loss ◽  
Economic Losses ◽  
Energy Yield ◽  
Solar Pv ◽  
Financial Loss ◽  
Grid Systems ◽  
Dust Density

Soiling losses of photovoltaic (PV) panels due to dust lead to a significant decrease in solar energy yield and result in economic losses; this hence poses critical challenges to the viability of PV in smart grid systems. In this paper, these losses are quantified under Qatar’s harsh environment. This quantification is based on experimental data from long-term measurements of various climatic parameters and the output power of PV panels located in Qatar University’s Solar facility in Doha, Qatar, using a customized measurement and monitoring setup. A data processing algorithm was deliberately developed and applied, which aimed to correlate output power to ambient dust density in the vicinity of PV panels. It was found that, without cleaning, soiling reduced the output power by 43% after six months of exposure to an average ambient dust density of 0.7 mg/m3. The power and economic loss that would result from this power reduction for Qatar’s ongoing solar PV projects has also been estimated. For example, for the Al-Kharasaah project power plant, similar soiling loss would result in about a 10% power decrease after six months for typical ranges of dust density in Qatar’s environment; this, in turn, would result in an 11,000 QAR/h financial loss. This would pose a pressing need to mitigate soiling effects in PV power plants.

scholarly journals Adoption of Satellite Offices in Response to a Pandemic: Sustainability and Infection Control

2021 ◽  
Vol 13 (14) ◽  
pp. 8008
Author(s):  
Seungbeom Kim ◽  
Yooneun Lee ◽  
Byungchul Choi
Keyword(s):  
Infection Control ◽  
Work Environment ◽  
Fuel Consumption ◽  
Environmental Sustainability ◽  
Carbon Emission ◽  
Work Environments ◽  
Remote Work ◽  
Simulation Experiments ◽  
Office Environment ◽  
Potential Risks

The office environment has changed rapidly due to the recent COVID-19 outbreak. Companies consider various types of remote work environments to contain the spread of the virus. Among them, a satellite office is a type of remote work environment where a number of employees are allocated to their nearest office. The benefits from satellite offices are twofold: The significant reduction of travel distance also reduces the amount of carbon emission and fuel consumption. In addition, dividing employees into smaller groups significantly reduces the potential risks of infection in the office. This paper addresses a satellite office allocation problem that considers social and environmental sustainability and infection control at work. In order to evaluate the effect of different satellite office allocation, quantitative measures are developed for the following three criteria: carbon emission, fuel consumption, and the probability of infection occurrence at work. Simulation experiments are conducted to investigate different scenarios of regional infection rate and modes of transportation. The results show that adopting satellite offices not only reduces carbon emission and fuel consumption, but also mitigates business disruption in the pandemic.

On Analysis Economic Loss Appraisal Method for Geological Disasters

2012 ◽  
Vol 594-597 ◽  
pp. 2272-2276
Author(s):  
Shi Gui Li ◽  
Qing Lin Yi ◽  
Juan Juan Wu
Keyword(s):  
Reference Value ◽  
Economic Loss ◽  
Economic Losses ◽  
Geological Disasters ◽  
Effective Evaluation ◽  
Valuation Method ◽  
Geological Disaster ◽  
Appraisal Method ◽  
Qianjiangping Landslide ◽  
China’S Economy

China is one of the most serious national which does harm to geological disasters, and the geological disasters have effect on China’s economy. Therefore, the effective evaluation for the economic losses caused by geological disasters has some reference value. This paper mainly introduces the geological disaster economic losses structure drawing and evaluated methods which include human capital method, shadow valuation method, market valuation method, investigation appraisal method and coefficient of proportionality method, and analyzes different economic losses should adopt different appraisal method. And take the Qianjiangping landslide for instant, this paper introduces how to evaluate landslide disasters economic loss. The idea and method have certain guiding significance to geological disaster economic losses evaluation.

scholarly journals Aptamer-targeting of Aleutian mink disease virus (AMDV) can be an effective strategy to inhibit virus replication

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Taofeng Lu ◽  
Hui Zhang ◽  
Jie Zhou ◽  
Qin Ma ◽  
Wenzhuo Yan ◽  
...  
Keyword(s):  
Disease Virus ◽  
Magnetic Beads ◽  
Inhibitory Effect ◽  
Three Dimensions ◽  
Economic Losses ◽  
Effective Vaccine ◽  
Stem Loop ◽  
Aleutian Mink Disease Virus ◽  
Random Library

AbstractAleutian mink disease (AMD), which is caused by Aleutian mink disease virus (AMDV), is an important contagious disease for which no effective vaccine is yet available. AMD causes major economic losses for mink farmers globally and threatens some carnivores such as skunks, genets, foxes and raccoons. Aptamers have exciting potential for the diagnosis and/or treatment of infectious viral diseases, including AMD. Using a magnetic beads-based systemic evolution of ligands by exponential enrichment (SELEX) approach, we have developed aptamers with activity against AMDV after 10 rounds of selection. After incubation with the ADVa012 aptamer (4 μM) for 48 h, the concentration of AMDV in the supernatant of infected cells was 47% lower than in the supernatant of untreated cells, whereas a random library of aptamers has no effect. The half-life of ADVa012 was ~ 32 h, which is significantly longer than that of other aptamers. Sequences and three dimensions structural modeling of selected aptamers indicated that they fold into similar stem-loop structures, which may be a preferred structure for binding to the target protein. The ADVa012 aptamer was shown to have an effective and long-lasting inhibitory effect on viral production in vitro.

Spatial-Temporal Dynamics of Disease Burden Attributable to Pm2.5 Exposure in China From 2000 to 2016

2021 ◽  
Author(s):  
Ting Cao
Keyword(s):  
Policy Making ◽  
Disease Burden ◽  
Temporal Dynamics ◽  
Comprehensive Evaluation ◽  
Fine Particulate Matter ◽  
Economic Loss ◽  
Northwest China ◽  
Economic Losses ◽  
Air Pollution Control ◽  
Chinese Yuan

Abstract In recent years, long-term exposure to ambient fine particulate matter (PM2.5) has slowly increased both morbidity and mortality for Chinese people, becoming a leading problem for public health efforts. However, spatial-temporal dynamics of disease burden attributable to PM2.5 exposure still lacks a comprehensive evaluation so as to provide inadequate supports for policy making and improvement. Here, we used the exposure-response function to derive the spatial-temporal dynamics of disease burden attributable to PM2.5 pollution in China. We found the fact that economic loss attributable to PM2.5 increased by 93% from 35 billion Chinese Yuan (95% CI: 14-52) to 536 billion Chinese Yuan (95%CI: 236-753) during the period of 16 years. Digging further, we discovered a substantiate level of regional differences, with the disease burden being the most severe in East China and the least severe in the Northwest China. Other than that, there existed a spatial aggregation of health-related economic losses among Chinese cities. Our paper made an evaluation on the spatial-temporal dynamics of health effects attributed to PM2.5, an evaluation that could provide more insights to future policy making of the air pollution control for China and other developing countries.

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