Dietary supplementation of Neem (Azadirachta indica) leaf extracts improved growth performance and reduced production cost in broilers

Background and Aim: Global trend to remove the antibiotic growth promoter (AGP) from animals contributes to the exploration of successful measures to sustain production and reduces the intestinal diseases in the post-AGP era. Plant extracts, therefore, have been used to improve performance and intestinal health. Here, we conducted a study to evaluate the effects of neem (Azadirachta indica) leaf extracts (NLE) as alternatives to AGPs in broiler chickens. Materials and Methods: Sixty day-old broiler chicks were assigned to 12-floor pens, each stocked with five birds and divided into three treatment groups of four pens per treatment. The groups were: Negative control, basal diet without additives; positive control, basal diet with antibiotics and vitamins; and NLE treated group, basal diet supplemented with 0.1% aqua extract of neem leaves. Results: Overall feed intake was significantly (p≤0.05) highest in the positive control. Higher body weight, higher dressing percentage, and lower feed conversion ratio were observed in birds treated with NLE compared to the negative control group (p≤0.05) but not the positive control group (p>0.05). There was no significant variation in hematology between different groups. Furthermore, the economic evaluation indicated that the NLE treatment was found cheaper than control and antibiotic treatment in cost-benefit analysis. Conclusion: We suggest NLE might be a cheaper alternative to antibiotics in broiler production as indicated by improved body weight and feed efficiency.

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Growth Performance, Serum Biochemical Indices, Duodenal Histomorphology, and Cecal Microbiota of Broiler Chickens Fed on Diets Supplemented with Cinnamon Bark Powder at Prestarter and Starter Phases

Animals ◽

10.3390/ani11010094 ◽

2021 ◽

Vol 11 (1) ◽

pp. 94

Author(s):

Mohammed M. Qaid ◽

Saud I. Al-Mufarrej ◽

Mahmoud M. Azzam ◽

Maged A. Al-Garadi ◽

Hani H. Albaadani ◽

...

Keyword(s):

Body Weight ◽

Broiler Chickens ◽

Body Weight Gain ◽

Basal Diet ◽

Positive Control ◽

Negative Control ◽

Broiler Chicks ◽

Feed Conversion ◽

Serum Globulin ◽

Maximum Improvement

Ross 308 broiler chicks (n = 240) aged 1 day were assigned to five groups for eight replicates (six chicks for each) (3♂ and 3♀). Basal dietary groups were supplemented by 2000, 4000, and 6000 mg/kg cinnamon (CN) for 21 days. Basal diet alone was used as a negative control, and basal antibiotic diet (Colimox) was used as a positive control. At 10, 14, and 21 days of age, chicks that received 2000 mg CN and Colimox had a higher body weight, resulting in an increase in body weight gain. CN also resulted in the maximum improvement in the feed conversion ratio and feed efficiency over 1–21 days at the level of 2000 mg/kg. At days 10, the maximum relative breast weight was 2000 mg/kg of CN. Mean serum albumin concentrations, duodenal villus height, and goblet cell density increased (p < 0.05) by 2000 mg/kg of CN, and mean serum globulin and total protein concentrations and crypt depth increased (p < 0.05) by 6000 mg/kg of CN compared with control. Increased cecal Escherichia coli number was CN dose-dependent. In conclusion, dietary inclusion of 2000 mg/kg CN can be applied as an alternative to in-feed antibiotics for broiler starter diet.

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Efficacy of tulsi leaves and neem leaves extract in broiler production

Bangladesh Journal of Veterinary Medicine ◽

10.3329/bjvm.v11i1.17728 ◽

2014 ◽

Vol 11 (1) ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

S Khatun ◽

M Mostofa ◽

F Alom ◽

J Uddin ◽

MN Alam ◽

...

Keyword(s):

Body Weight ◽

Weight Gain ◽

Body Weight Gain ◽

Control Group ◽

Broiler Chicks ◽

Growth Promoter ◽

Neem Extract ◽

Final Body Weight ◽

Neem Leaves ◽

Group A

The efficacy of tulsi (Ocimum sactum) and neem (Azadirachta indica) leaves extract as a growth promoter were studied in broiler. A total of 40 day-old broiler chicks were purchased from Kazi hatchery and after three days of acclimatization the chicks were randomly divided into four groups (n=10). No vaccination schedule was practiced and no antibiotic was added in ration of group A, B, C, and D respectively. Group A served control without any supplements while group B, C and D were supplemented with combination of tulsi and neem extract @ 1 ml, 2ml and 3 ml/liter of drinking water. Live body weight gain was recorded weekly up to 6th weeks and hematological studies were performed at 21st and 42nd day of experiments. At the end of 42nd day of experiment final body weight of group A, B, C and D were 1561± 12.10 g, 1698± 12.87 g, 1608± 12.04 g and 1763± 13.28 g, respectively. The birds of group D utilized their feed more efficiently among the treatment groups (p<0.05). The net body weight gain were, 1533± 11.98 g, 1443± 11.32 g and 1588± 12.10 g in treated groups compared to control group (1393± 11.07 g ) and total net profit per broiler was 19.08, 40.10, 20.68 and 45.07 Taka , respectively. Hematological parameterss (TEC, PCV, Hb and ESR) were not significantly changed among the treated and control group suggesting no side effects of herbal extracts in broiler. It can be concluded that tulsi and neem extract is economic and safe in broiler production.DOI: http://dx.doi.org/10.3329/bjvm.v11i1.17728 Bangl. J. Vet. Med. (2013). 11 (1): 1- 5

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Effects of Curcuma Zedoaria (Shoti) on Growth Performance and Hemato-Biochemical Parameters in Broiler

Research in Agriculture Livestock and Fisheries ◽

10.3329/ralf.v7i2.48872 ◽

2020 ◽

Vol 7 (2) ◽

pp. 293-301

Author(s):

TM Rahsin Kabir ◽

Nahid Nawrin Sultana ◽

Tangila Ferdausi ◽

Muhammad Rakibul Hasan ◽

Nayamul Bashar ◽

...

Keyword(s):

Body Weight ◽

Biochemical Parameters ◽

Biochemical Analysis ◽

Treated Group ◽

Positive Control ◽

Negative Control ◽

Control Group ◽

Broiler Chicks ◽

Collect Blood Sample ◽

Growth Performances

The experiment was conducted on “Cobb-500” broiler chicks to study the effects of Curcumazedoaria (shoti) on growth performances and haemato-biochemical parameters. A total of twentybroilers chicks (16 days old) were randomly divided into five equal groups (n=4). Three groups ofbroilers fed shoti powder at the rate of 10%; 20%; 30% (w/w) with other ingredients for 22 days.Broilers chicks fed on maize-soybean were considered as positive control while non-protein controlwas regarded as negative control. The results showed that body weight of broilers fed 10% and 20%shoti meal grew very close to those of control (maize-soybean) group. After having completed thefeeding trial, the birds were sacrificed to collect blood sample for and biochemical analysis .Weightsof different organs and length of intestine were also measured. Results showed that decreaseddressed weight, weight of skin and liver were found in 30% shoti treated group compared to proteincontrol group. Intestinal weight was highest in 30% shoti treated group but length was similar to theprotein control group. Total erythrocytes count, hemoglobin content and PCV value were founddecreased in shoti treated group compared to protein control group but ESR value was highest in10% shoti treated group. Total cholesterol was found to be decreased in the birds fed on shoticompared to protein control and significantly higher than non-protein control group. Triglyceride valuedecreased in 10% shoti treated group compared to protein and non-protein control group. IncreasedHDL value was found in 10% shoti treated group compared to control groups and 20 % and 30 %shoti treated groups. Result of this experiment showed that body weight of birds significantly (p<0.05)increased in all shoti treated groups. Further investigations are necessary by using differentpercentages of shoti and other shoti type feed to determine the effects of this feed supplement onanimal’s physiology. Res. Agric., Livest. Fish.7(2): 293-301, August 2020

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Hepatoprotective Role of AV/LCP/18 In CCl4 Induced FLKS Syndrome in Commercial Broilerst

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY ◽

10.21887/ijvsbt.v12i2.3738 ◽

2016 ◽

Vol 12 (2) ◽

Author(s):

P. M. Sonkusale ◽

Pratik N. Inglepatil ◽

Siddharth V. Jamadade

Keyword(s):

Body Weight ◽

Treatment Group ◽

Protein Profile ◽

Negative Control Group ◽

Positive Control ◽

Negative Control ◽

Control Group ◽

Broiler Chicks ◽

Mean Values ◽

Group B

A total of 75 day old broiler chicks were divided into three equal groups. Group A served as negative control. Group B (positive control) and C (treatment group) were intoxicated with oral administration of CCl4 @ 1 ml/kg body weight after every 3rd day during 15-28 days of age. Group C was given AV/LCP/18 @ 0.10 ml / chick / day in drinking water during 29th-42nd day of age. At the end of experiment, significantly (P is less than 0.01) higher mean body weight and lower FCR was observed in treatment group C as compared to positive control group B. Similarly, significantly (P is less than 0.05) decreased levels of SGOT, SGPT, cholesterol, triglycerides, creatinine and higher mean values of serum protein profile along with mild degenerative changes in liver and kidney of broilers in group C were observed as compared to group B indicating therapeutic efficacy of AV/LCP/18 in ameliorating the toxic effects or FLKS induced by CCl4 in commercial broilers

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Phytogenic additive as an alternative to growth promoters in broiler chickens

Ciência Rural ◽

10.1590/s0103-84782009000200032 ◽

2009 ◽

Vol 39 (2) ◽

pp. 522-527 ◽

Cited By ~ 10

Author(s):

Gerson Neudí Scheuermann ◽

Anildo Cunha Junior ◽

Lucas Cypriano ◽

Alexandre Mossate Gabbi

Keyword(s):

Body Weight ◽

Broiler Chickens ◽

Positive Control ◽

Negative Control ◽

Feed Additive ◽

Broiler Chicks ◽

Growth Promoter ◽

Feed Conversion ◽

Growth Promoters ◽

The Cost

This study evaluated a phytogenic feed additive for broiler chickens. A total of 1,632 broiler chicks were distributed into four treatments: negative control (without growth promoter); positive control (avilamycine, 10ppm + colistin, 15ppm); and two alternative treatments with 150ppm of phytogenic additive, one with a reduced Ca and P levels diet (PA-R1) and the other with lower energy, and amino acids, besides Ca and P (PA-R2). The trial was conducted with 12 replicates, each consisted of a pen with 34 birds. The alternative diets showed body weight intermediate to the two controls at 42 days, with no significant (P>0.05) treatment effect on feed conversion ratio. No treatment differences (P>0.05) on carcass yield and composition was observed. There was a tendency of abdominal fat lipids saturation, when the phytogenic additive was used, as possible consequence of a decreased level of soybean oil in the diets. A difference (P<0.001) on ingredient consumption profile was observed between the treatments. All together, this study showed a possibility to reduce the cost of total feed used to produce a broilers or a ton of body weight by the utilization of the tested phytogenic additive.

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Effect of dietary supplementation of ginger extract on growth, carcass characteristics and haematological parameters in broilers

Asian Journal of Medical and Biological Research ◽

10.3329/ajmbr.v3i2.33571 ◽

2017 ◽

Vol 3 (2) ◽

pp. 211-215 ◽

Cited By ~ 1

Author(s):

Sudipta Talukder ◽

Md Mehedi Hasan ◽

Zakaria Al Noman ◽

Yousuf Ali Sarker ◽

Torun Kumar Paul ◽

...

Keyword(s):

Body Weight ◽

Broiler Chickens ◽

Negative Control Group ◽

Positive Control ◽

Negative Control ◽

Control Group ◽

Growth Promoter ◽

Feed Conversion ◽

Ginger Extract ◽

Final Body Weight

This study evaluated the effect of ginger on the growth performance, carcass quality of broiler chickens. 20 broiler chickens were randomly selected into two treatment groups identified as T1 and T2 with a positive control and a negative control group. Each treatment contained with five birds. Birds on T1 were treated with 1% ginger extract and T2 was treated with 2% ginger extract via drinking water. Significant variations (p<0.05) existed between the control and other treatments in mean final body weight, dressed weight, daily feed intake and feed conversion ratio. At the end of experiment (35th day) for 1% ginger extraction treatment the live body weight is 1746gm (p<0.05), dressing weight 1106.4 (p<0.05) and FCR is 1.67(p<0.05). The usage of the test ingredients had a significant effect (p<0.05) on dressing percentage. Supplementation of ginger improves the performance of broilers when added at the rate of 1% of broiler ration and can be a possible alternative to antibiotic growth promoter in the feeding of broiler chicken.Asian J. Med. Biol. Res. June 2017, 3(2): 211-215

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Effects of aqueous extract of Neem (Azadirachta indica) leaves as growth promoter and anti-colibacillosis in broilers

Bangladesh Journal of Animal Science ◽

10.3329/bjas.v43i2.20715 ◽

2014 ◽

Vol 43 (2) ◽

pp. 138-141 ◽

Cited By ~ 1

Author(s):

SK Sarker ◽

M Mostofa ◽

F Akter ◽

MM Rahman ◽

MR Sultana

Keyword(s):

Body Weight ◽

Aqueous Extract ◽

Body Weight Gain ◽

Hematological Parameters ◽

Control Group ◽

Broiler Chicks ◽

Growth Promoter ◽

Neem Leaves ◽

Group A ◽

Group B

The study was conducted to determine the efficacy of aqueous extract of Neem leaves against colibacillosis and as a growth promoter in broilers. A total of 40 commercial day-old broiler chicks were randomly divided into four equal groups; viz. A, B, C and D. Group A was kept as non-treated control, Group B and C was treated with 1% Neem leaves in drinking water for six weeks, and colibacillosis was induced at 2nd week in group C and D. In group D, Neem leaves treatment continued from 2nd to 6th week after the colibacillosis induction to compare its antibacterial efficacy to prophylactic effect. Escherichia coli induction rate was 200µl per bird where 1 ml contains approximately 1X106 CFU (Colony Forming Unit). Data were recorded for live body weight, weekly gain in weight and hematological parameters of birds for six weeks. Clinical examination and antibacterial sensitivity studies suggests administration of aqueous extract of Neem leaves significantly (p<0.001) improved body weight gain in the Neem treated groups but did not prevent E. coli induced colibacillosis in broilers.DOI: http://dx.doi.org/10.3329/bjas.v43i2.20715 Bang. J. Anim. Sci. 2014. 43 (2): 138-141

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Gynura procumbens (Lour.) Merr. Leaves Against Mice’s Antibody Titer

JURNAL PROTEKSI KESEHATAN ◽

10.36929/jpk.v8i2.154 ◽

2019 ◽

Vol 8 (2) ◽

pp. 13-19

Author(s):

Rahimatul Uthia ◽

Elin Resti Ananda ◽

Ifora Ifora

Keyword(s):

Body Weight ◽

Antibody Titer ◽

White Male ◽

Positive Control ◽

Negative Control ◽

Control Group ◽

Male Mice ◽

Defense System ◽

Leaf Extracts ◽

Antibody Titers

The body's defense system can be enhanced by certain compounds that are immunostimulant. An antibody titer is a measure of the body's level of immunity to a disease. Titers are usually expressed in terms of the number of times they can thin the blood until they cannot find any more antibodies. This study aims to determine the activity of the extracts of the leaves of Gynura Procumbens (Lour.) Merr. against antibody titers, the number, and percentage of leukocyte cells of white male mice. 25 mice were divided into 5 groups consisting of negative control, positive control, group dose 75 mg/kg body weight, 150 mg/kg body weight, 300 mg/kg body weight. The extract is given for 7 days orally. The results showed that the administration of leaf extracts can increase antibody titers and increase with increasing doses, as well as increasing the total number of leukocytes and the percentage of leukocyte cells significantly (P <0.05).

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Effect of Spearmint (Mentha spicata) on Performance and Blood Serum Parameter of Broiler

JOURNAL OF SOCIAL SCIENCE RESEARCH ◽

10.24297/jssr.v8i2.6618 ◽

2015 ◽

Vol 8 (2) ◽

pp. 1600-1606

Author(s):

Huda Mohammed Saad Elamin ◽

K.A. Mohamed ◽

Mukhtar A. Mukhtar

Keyword(s):

Body Weight Gain ◽

Basal Diet ◽

Positive Control ◽

Negative Control ◽

Feed Consumption ◽

Broiler Chicks ◽

Growth Promoter ◽

Feed Conversion ◽

Mentha Spicata ◽

Dietary Treatments

The present study was planned to evaluate the response of broiler chicks to diets containing graded levels of spearmint (Mentha spicata). A total of 200 , five days-old, unsexes (cob) broiler chicks were used. Chicks were weighed individually and assigned randomly to five groups of 40 chicks per treatment and each treatment was subdivided to four replicates of 10 chicks each. Five experimental diets were formulated (A, B, C, D and E) to meet the nutrient requirements of broiler chicks. The experimental parameters examined were growth performance, serum metabolite, electrolyte and enzyme activities and economic appreciable. Diet (A) Negative Control (NC), a basal diet without antibiotic or spearmint, diet B as Positive Control (PC) basal diet supplemented with antibiotic (Neomycin 16 mg/Kg), diets C,D and E were basal diet supplemented with spearmint at levels of 1,1.5,and 2%, respectively. Result obtained showed that addition of spearmint improved significantly (P<0.05) the performance (body weight gain and feed conversion ratio) of broiler chicks compared to group fed on NC while no significant (P<0.05) differences between chicks fed on diets supplemented with spearmint and PC group observed, no significantly difference was found in feed consumption between all treated groups. The mortality rate did not influenced by the dietary treatments. Results revealed no significant differences (P<0.05) observed among all treatment groups in the carcass dressing percentages, Supplementation of broiler diets with spearmint at various levels was resulted in significant (p>0.05) reduction of abdominal fat, serum cholesterol, and AST enzyme activity compared to both NC and PC groups while the levels of urea, total protein, glucose and ALP and serum electrolytes levels remained unchanged. The highest profitability ratio (1.13) was obtained from the diet (E) supplemented with 2% spearmint. This study showed that spearmint when added as growth promoter in broiler diets has a similar effect on performance as that of antibiotic without any adverse effects.

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In vivo antidiarrheal study of ethanolic extracts of Mikania cordata and Litsea monopetala leaves

Bangladesh Journal of Pharmacology ◽

10.3329/bjp.v10i3.23402 ◽

2015 ◽

Vol 10 (3) ◽

pp. 562 ◽

Cited By ~ 2

Author(s):

Fatema Nasrin ◽

Md. Lukman Hakim

Keyword(s):

Body Weight ◽

Castor Oil ◽

Leaf Extract ◽

Positive Control ◽

Control Group ◽

P Value ◽

Leaf Extracts ◽

Ethanolic Extracts ◽

Antidiarrheal Activity

In this study the antidiarrheal activity of ethanolic extracts of the leaves of Mikania cordata and Litsea monopetala was evaluated. Diarrhea was induced in mice by oral administration of castor oil (0.5 mL) 30 min after the administration of the extracts. During a 4 hour study the number of diarrheal feces and percentage inhibition of the extracts (200 and 400 mg/kg body weight) was determined. Loperamide (3 mg/kg body weight) served as standard and belonged to the positive control group. The extracts exhibited potent antidiarrheal activity as well as achieved statistically significant p value (p<0.01 and p<0.05) compared to control group. Among the extracts the highest percentage inhibition of defecation (60%) was recorded for leaf extract (400 mg/kg body weight) of L. monopetala. So, the study corroborates the significant antidiarrheal activity of M. cordata and L. monopetala leaf extracts and raises the demand of further sophisticated investigation.

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