scholarly journals Comparative Evaluation of Necessity of Antibiotic Administration Following Dental Extraction among Population of Age Group 30-60 Years - Triple Blinded Randomized Controlled Trial

2021 ◽  
Vol 10 (32) ◽  
pp. 2554-2558
Author(s):  
Sasidharan Sivakumar

BACKGROUND The use of antibiotics as prophylactic prescriptions remains a controversy in dentistry. The current study was done to evaluate the necessity of antibiotic administration following dental extraction among population of 30 – 60 year old age groups. METHODS This is a triple blinded trial with trial registry number CTRI / 2019 / 12 / 022342 in which the 60 study participants were randomized and allocated in a ratio of 1 : 1 : 1 to three groups A (amoxicillin 500 mg t.d.s), B (clindamycin 150 mg t.d.s as a mouthrinse), C (no antibiotic) by lot method. The study proceeded after ethical committee approval and informed consent from the participants. Medically compromised patients, patients in menstruation period, lactation and pregnancy period, test drug hypersensitive patients, tooth with abscess or cyst were excluded and patients of 30 – 60 years old reporting with the complaint to Best Dental Science College, Madurai, were included in the study. The tooth was extracted, and evaluated on 3rd, 7th and 14th day post-operatively. RESULTS The non healing parameters were observed in percentages of 9.7, 6.2 and 6.2 in group A, B and C group during the 14th day clinical evaluation. The presence of non-healing parameters was insignificant between three groups. CONCLUSIONS Prophylactic antibiotics following dental extraction is unnecessary until the patient is at a state of high risk of infection. Thereby, as a dentist we could combat a step towards a developing major public health problem, “Antibiotic Resistance”. KEY WORDS Drug Resistance, Tooth Extraction, Drug Utilization, Antibiotic Awareness, Prophylaxis

Author(s):  
Abubakar Danraka ◽  
Salamatu Orakwelu ◽  
Godspower Onavbavba

Drug abuse has now become a major public health problem in Nigeria requiring urgent attention. Although drug abuse cut across all age groups, the youths are however the most affected. This study aimed at assessing Community Pharmacists involvement in the rehabilitation of drug abuse victims. The study was carried out in Abuja Municipal Area Council, questionnaires were administered to Community Pharmacists practicing within the Area Council. A total of 176 Community Pharmacists participated in the study, and slightly above a quarter (27.43%) of them had post-graduate degrees. More than three-quarters (79.5%) of the study participants had received training on drug abuse. A total of 89.2% of the study participants had come across persons suspected to be abusing prescription medicines. Almost all (96.6%) of the study participants indicated that they are willing to advise persons suspected to be abusing drugs on the dangers of drug abuse, and 88.1% of the study participants had spoken to clients concerning abuse of prescription medicines. Also, more than three-quarters (80.1%) of the study participants indicated that pharmacists’ role in the prevention of drug abuse is very important. The study has revealed that Community Pharmacists can play an invaluable role in the rehabilitation of drug abuse victims in Nigeria.


2020 ◽  
Vol 16 (7) ◽  
pp. 1015-1027
Author(s):  
Mohammad Bagherniya ◽  
Zahra Khorasanchi ◽  
Mina S. Bidokhti ◽  
Gordon A. Ferns ◽  
Mitra Rezaei ◽  
...  

Background: Vitamin D deficiency is a common medical condition worldwide. In Iran, it has been reported that between 30-90% of people have vitamin D deficiency. However, its distribution in different parts of the country and among different age and regional groups is unclear. Therefore, the aim of this study was to review the recent literature on vitamin D deficiency in Iran. Methods: The literature review was performed using Web of Science, PubMed-Medline, Scopus and Scientific Information Database (SID) with a cut-off date of November 2016 to identify articles on vitamin D status in Iran published in the last 10 years. Studies in English and Persian that reported vitamin D levels in male and female subjects of all age groups and in healthy populations were included. Results: From 325 studies that were initially retrieved, 82 articles met the inclusion criteria. A high prevalence of vitamin D deficiency was reported, and in some regions, this was reported as >90% and was found in all age groups and in all regions of Iran. Conclusion: This review highlights the very high prevalence of vitamin D deficiency in Iran. It will be important to recognize the importance of vitamin D deficiency as a major public health problem in Iran.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
J Narusyte ◽  
K Kosidou ◽  
C Dalman

Abstract Background Suicide is a major public health problem. A detailed description of healthcare use prior to suicide can serve to improve prevention strategies. The aim of the study was to describe the patterns of primary, specialized outpatient, and inpatient healthcare use from two weeks and up to one year prior to suicide in Stockholm County. Methods The study population included all 15 year or older suicide victims who died in Stockholm County 2011-2016 (n = 1950) identified through National Cause of Death Registry. Data on number of visits and contacts with healthcare among suicide victims were obtained from VAL healthcare use registry in Stockholm County. Healthcare use was depicted from one year to up to two weeks prior to suicide death. Results Preliminary results showed that there were 65% and 57% of women and men, respectively, who had at least one contact with healthcare during the last two weeks before suicide death. Measured one year prior to suicide, there were 93% of women and 85% of men who had at least one contact with healthcare. Among those who had at least one contact with healthcare two weeks prior to suicide, there were 16% of women and 12% of men who were hospitalized, 55% of women and 47% of men who had a contact with specialized outpatient care, and 32% of women and 27% of men who had a contact with primary healthcare. The proportion of those who did not have any contact with healthcare during the six months prior to suicide decreased gradually with increasing age among men (23% at ages of 15-24 years old and 7% at ages of 65 and older). There were on average 7% of women in all age groups who did not have any contact with healthcare during the six months prior to suicide. Conclusions The majority of the suicide victims had a contact with healthcare during the last year prior to suicide death. The findings suggest that suicide prevention efforts may target improved tools for clinically-based risk assessment. Key messages The majority of the suicide victims had at least one contact with healthcare during the last year prior to suicide death. Those who did not have any contact with healthcare during six months prior to suicide were more likely to be young men.


2021 ◽  
Author(s):  
Amanuel Mulugeta ◽  
Atsede Assefa ◽  
Atsede Eshetie ◽  
Birhanie Asmare ◽  
Meseret Birhanie ◽  
...  

Abstract Background: Malaria is disease caused by plasmodium species and transmitted by the bite of female anopheles mosquito. Globally, it is still the major public health problem that causes morbidity and mortality especially in tropical and sub-tropical African countries including Ethiopia. The objective of this study was to assess the Six year trend of malaria at University of Gondar Specialized Referral Hospital, northwest Ethiopia, from 2014-2019Method: A retrospective study was conducted by reviewing the laboratory registration logbook at University of Gondar Specialized Referral Hospital by using data extraction tool. The data was analysized by SPSS version 20. Descriptive statistics was used to summarize the socio-demographic characteristics of study participants and presented by graphs, tables and texts. The binary logistic regression was also used test the association of trend of malaria and different factors like sex, age, year, and season. Result: From a total 17,500 malaria suspected patients, 1341 (7.7%) were confirmed for malaria and (47.2%), (45.6%) and (7.2%) were P.vivax, P. falciparum and mixed infection, respectively. P.vivax was the predominant species in the first three years and P. falciparum became the predominant species in the last three years. The trend prevalence was showed a fluctuated significantly decrement. It decreased by 68%, 60% and 69% in the year of 2017, 2018 and 2019 compare to 2014, respectively. The positivity rate were significantly higher in the males (1.41 times higher) than females. It was also significantly higher in lower age groups compare to the older age groups (> 54 years old). It was 1.60, 1.64, 2.45 and 1.82 times higher in the age group of < 5, 5-14, 15-24 and 25-54 years old, respectively.Conclusion: There has been a significant declining trend of malaria in the study area. However, it is still a major health problem and requires extra efforts for further reduction. Even, autumn was the season when the highest peak of malaria cases in was observed, there was high fluctuation from year to year. Therefore, control activities should be continued and strengthened manner in the study area considering these variability.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Dr. Senthil kumar ◽  
Dr. Franklin Shaju M.K m k ◽  
Dr. Vijaya Senthil Kumar kumar ◽  
Dr. A. velmurugan

Background of the study: Stroke is a major public health problem that ranks in the top four causes of death in most of the countries and is responsible for a large proportion of the burden of neurologic disorders. Patients with stroke have poor balance because they cannot control dynamically the size of the base of support or the location of the line of gravity. Perturbation training undergoes the maximal sway possible without losing his balance. Objective of the study: The objective of the study is to find the effects of rolling board perturbation training on balance among hemiparetic stroke patients. Methodology: Thirty clinically diagnosed hemiparetic stroke patients were selected based on the inclusion and exclusion criteria. They were randomly allocated into two groups (Group A and Group B) consists of 15 subjects each. Group A received conventional physiotherapy alone and group B received rolling board perturbation training along with conventional physiotherapy. Intervention lasted for 4 weeks, three days in a week and one hour per day. Balance was measured before and after 4 weeks of intervention by berg balance scale. Conclusion: Both conventional physiotherapy alone and rolling board perturbation training along with conventional physiotherapy significantly improved balance among hemiparetic stroke patients. When comparing both rolling board perturbation training along with conventional physiotherapy is more effective than conventional physiotherapy alone in improving balance among hemiparetic stroke patients.


2018 ◽  
Vol 6 ◽  
pp. 205031211878674 ◽  
Author(s):  
Jemal Mohammed ◽  
Fitsum Weldegebreal ◽  
Zelalem Teklemariam ◽  
Habtamu Mitiku

Background: Schistosoma mansoni is a major public health problem. Different studies reported unidentified sites in Ethiopia with variable prevalence and intensity, but there is no report from this study area. Objective: To assess the clinico-epidemiology, malacology, risk factors, and community awareness of S. mansoni in Haradenaba and Dertoramis kebeles in the Bedeno district, eastern Ethiopia. Methods: A cross-sectional study was conducted among 1011 study participants in 413 systematically selected households from Haradenaba and Dertoramis kebeles from 30 June 2016 to 30 July 2017. Data were collected by using pretested, structured questionnaires, clinical examinations, and stool examinations. Stool samples were processed by the Kato-Katz method and examined microscopically. Snails were collected by scooping from water contact points. Data were analyzed using SPSS, version 16 statistical software. Result: The overall prevalence of S. mansoni was 35.7%. Heavy-intensity infection was detected in 8.9% of the study participants. Results included: participants who were unaware about the possible source of infection (adjusted odds ratio: 2.95; 95% confidence interval: 1.25, 7.95), modes of transmission (adjusted odds ratio: 5.51; 95% confidence interval: 3.52, 12.51), prevention (adjusted odds ratio: 4.01; 95% confidence interval: 2.00, 8.75) about schistosomiasis/bilharziasis were more likely infected with S. mansoni than those who were aware. Participants who swim or bathe in the river were more likely infected with S. mansoni than those who do not (adjusted odds ratio: 6.41; 95% confidence interval: 3.15, 11.25). Biomphalaria pfeifferi snails were collected from all water bodies in Haradenaba and Dertoramis, but they did not shed schistosome cercaria in the laboratory. Conclusion: S. mansoni infection is found in high magnitude in these study areas, despite not being previously reported. A majority of the study participants had low awareness about the source of infection, mode of transmission, and prevention methods of schistosomiasis. Efforts should be made to improve community awareness about transmission and prevention of schistosomiasis.


Author(s):  
Mami Taniuchi ◽  
Kamrul Islam ◽  
Md Abu Sayeed ◽  
James A Platts-Mills ◽  
Md Taufiqul Islam ◽  
...  

Abstract Background Diarrhea remains a major public health problem and characterization of its etiology is needed to prioritize interventions. However, most data are from single-site studies of children. We tested samples from participants of any age from 11 geographically diverse hospitals in Bangladesh to describe pathogen-specific burdens of diarrhea. Methods We utilized 2 existing diarrhea surveillance systems: a Nationwide network at 10 sentinel hospitals and at the icddr,b hospital. We tested stools from enrolled participants and nondiarrheal controls for enteropathogens using quantitative polymerase chain reaction and calculated pathogen-specific attributable fractions (AFs) of diarrhea. Results We analyzed 5516 patients with diarrhea and 735 controls. Overall, rotavirus had the highest attributable burden of diarrhea (Nationwide AF, 17.7%; 95% confidence interval [CI], 14.3–20.9%; icddr,b AF, 39.9%; 38.0–41.8%), followed by adenovirus 40/41 (Nationwide AF, 17.9%; 95% CI: 13.9–21.9%; icddr,b AF, 16.6%; 95% CI, 14.4–19.4%) and Vibrio cholerae (Nationwide AF, 10.2%; 95% CI, 9.1–11.3%; icddr,b AF, 13.3%; 95% CI: 11.9–15.1%). Rotavirus was the leading pathogen in children &lt;5 years and was consistent across the sites (coefficient of variation = 56.3%). Adenovirus 40/41 was the second leading pathogen in both children and adults. Vibrio cholerae was the leading pathogen in individuals &gt;5 years old, but was more geographically variable (coefficient of variation = 71.5%). Other attributable pathogens included astrovirus, norovirus, Shigella, Salmonella, ETEC, sapovirus, and typical EPEC. Conclusions Rotavirus, adenovirus 40/41, and V. cholerae were the leading etiologies of infectious diarrhea requiring hospitalization in Bangladesh. Other pathogens were important in certain age groups or sites.


2018 ◽  
Vol 54 (01) ◽  
pp. 001-010
Author(s):  
K Kalaivani ◽  
Prema Ramachandran

ABSTRACT Introduction: Anaemia in adolescent girls has been recognised as a major public health problem. The Mid-day meal programme guidelines envisage inclusion of 75 g/day of vegetables and use of iron fortified iodised salt for hot cooked meal. The National Iron Plus Initiative envisages weekly iron-folic acid (IFA) supplementation for adolescent girls; however, coverage and compliance have been reported to be low. Data from national surveys carried out in the last two decades were analysed to assess changes, if any, in Hb levels and prevalence of anaemia in adolescent girls. Material and Methods: Raw data from National Family Health Surveys (NFHS) -2, -3, and -4, District Level Household Surveys (DLHS) 2 and 4, and Annual Health Survey-related to Clinical, Anthropometric and Biochemical Components (AHS-CAB) were analysed to assess mean Hb, prevalence of anaemia and frequency distribution of Hb in adolescent girls. Comparison in these parameters was made between non-pregnant girls 10-14 years and 15-19 years of age in DLHS-2, -4 and AHS-CAB; in the 15-19 year age group comparisons were made between pregnant and nonpregnant girls in NFHS series and DLHS AHS series. Results: There were no clear and consistent changes in mean Hb, prevalence of anaemia and frequency distribution of Hb in pregnant and non-pregnant adolescent girls between NFHS-2, -3 and -4 either at national or at State level. However, there was a 0.7 and 1.3 g/dL increase in mean Hb levels in nonpregnant girls (10-19 yrs) between DLHS-2 and AHS-CAB and DLHS-4 States, respectively. The increase in mean Hb of pregnant girls (15-19 yrs) was 1.1 g/dL and 1.4g/dL in AHS-CAB and DLHS 4 States, respectively. There was significant reduction in prevalence of anaemia in both pregnant and non-pregnant girls between DLHS 2 and DLHS 4 and AHS-CAB at the aggregate level for each survey and in all States except Uttarakhand. Conclusion: There has been some improvement in Hb levels in adolescent girls in the last two decades. Improving dietary intake of vegetables and promoting use of iron fortified iodised salt in all households in the country have to be taken up so that iron intake across all age groups improves. This when combined with daily IFA supplementation for three months in a year in adolescent girls, might lead to sustained improvement in Hb.


2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Asmita Shrestha ◽  
Chet Kant Bhusal ◽  
Binjwala Shrestha ◽  
Kiran Dev Bhattarai

Background. Malnutrition is a major public health problem and most enveloping cause of morbidity and mortality among children and adolescents throughout the world. This study was aimed at assessing the nutritional status and associated factors among 6-10-year-old children in selected earthquake-affected areas of Gorkha district, Nepal. Methods. A community-based cross-sectional study among 420 mothers having children of age groups 6-10 years (with anthropometric measurement among children) was conducted using a mixed method in selected earthquake-affected areas of Gorkha district, Nepal, from October 2015 to April 2016. Gorkha was selected purposively from 14 earthquake-affected districts. Two village development committees were selected randomly among 6 having severe impact. Randomly, 5 wards were selected from each of the 2 village development committees. As the sample was 420, 42 children were selected randomly from every ward. Result. Among the 420 children, 31.9% were underweight, 51.9% were stunted, and 2.9% were wasted after the earthquake. Children who were more prone to being underweight were the following: male children (RR=1.34 95% CI: 1.01-1.78) and children from illiterate mothers (RR=2.49, 95% CI: 1.85-3.36), illiterate fathers (RR=1.73, 95% CI: 1.32-2.27), and homemaker mothers (RR=0.28, 95% CI: 0.20-0.38); children whose families were using nonimproved sources of water (RR=2.60, 95% CI: 1.07-6.60); and households having food insecurity (RR=12.97, 95% CI: 3.29-51.18). Similarly, children of illiterate fathers (RR=1.67, 95% CI: 1.41-1.97), children of illiterate mothers (RR=2.32, 95% CI: 1.91-2.83), children of homemaker mothers (RR=0.59, 95% CI: 0.49-0.70), children whose family were using treated water (RR=0.32, 95% CI: 0.15-0.67), and children from food insecure households (RR=10.52, CI: 4.05-27.33) were found to be stunted. After adjustment, children from households consuming nonimproved water were 6 times more likely (OR=6.75; 95% CI: 1.59-28.62) to be wasted. Conclusion. Illiterate mothers, illiterate fathers, mothers engaged in occupation other than household work, and food insecure households were found to be independent predictors of underweight and stunting. Nonimproved source of drinking water was found to be independent predictors of wasting.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Millicent H. Osti ◽  
Oliver Sokana ◽  
Sophie Phelan ◽  
Michael Marks ◽  
Margot J. Whitfeld ◽  
...  

Abstract Background Scabies, a parasitic disease of the skin, is a major public health problem, largely affecting children. Scabies is often complicated by impetigo which can result in serious complications including invasive infections and immune mediated diseases. Scabies and impetigo are reported to have high prevalence in tropical settings including the Solomon Islands. Methods We conducted a cross-sectional prevalence survey at Gizo Primary School in the Western Province of the Solomon Islands in August 2018. The diagnosis of scabies was based on criteria developed by the International Alliance for the Control of Scabies in 2018. Population attributable risk was calculated to determine the effect of scabies on the prevalence of impetigo, and both adjusted and unadjusted risk ratios were calculated to identify differences between sexes and age groups. Results A total of 324 students were assessed (47.5% of those enrolled at the school). The prevalence of scabies was 54.3% (95% confidence interval [CI] 48.7–59.8) and most disease was mild (68.8%). The prevalence was higher in males (63.5%; adjusted risk ratio [ARR] 1.4, 95% CI 1.1–1.7), and in those aged 10–12 years (61.4%; ARR 1.8, 95% CI 1.1–2.9 when compared to those aged 4–6 years). The prevalence of impetigo was 32.1%, with males more likely to be affected (41.7%, ARR 1.7, 95% CI 1.2–2.4) but with no significant differences between age groups. 63.5% of those with impetigo had scabies, corresponding to a population attributable risk of 11.8%. Conclusions There is a very high burden of scabies and impetigo among primary school students in Gizo. There is a critical need for the development and implementation of control programs in areas where scabies is endemic.


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