8 The Near Future of the Long Term: A Bricoleur’s World

2020 ◽  
pp. 206-214
Keyword(s):  
2017 ◽  
Vol 7 (2) ◽  
pp. 207-230 ◽  
Author(s):  
Mustafa Murat Yucesahin ◽  
Ibrahim Sirkeci

Syrian crisis resulted in at least 6.1 million externally displaced people 983,876 of whom are in Europe while the rest are in neighbouring countries in the region. Turkey, due to its geographical proximity and substantial land borders with the country, has been the most popular destination for those fleeing Syria since April 2011. Especially after 2012, a sharp increase in the number of Syrian refugees arriving in Turkey was witnessed. This has triggered an exponential growth in academic and public interest in Syrian population. Numerous reports mostly based on non-representative sample surveys have been disseminated whilst authoritative robust analyses remained absent. This study aims to fill this gap by offering a comprehensive demographic analysis of the Syrian population. We focus on the demographic differences (from 1950s to 2015) and demographic trends (from 2015 to 2100) in medium to long term, based on data from World Population Prospects (WPP). We offer a comparative picture to underline potential changes and convergences between populations in Syria, Turkey, Germany, and the United Kingdom. We frame our discussion here with reference to the demographic transition theory to help understanding the implications for movers and non-movers in receiving countries in the near future.


2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Masaki Nio ◽  
Motoshi Wada ◽  
Hideyuki Sasaki ◽  
Hiromu Tanaka ◽  
Masatoshi Hashimoto ◽  
...  

Abstract Background Although cancer occurrence following surgery for biliary atresia has gradually increased, the development of cholangiocarcinoma in a native liver survivor of biliary atresia is extremely rare. Case presentation A 3-month-old female patient with the correctable type of biliary atresia underwent a cystoduodenostomy. At 16 years of age, she underwent multiple surgeries including lysis of intestinal adhesions, ileostomy, and gastrojejunostomy at another hospital. At 54 years of age, she underwent lithotomy at the porta hepatis, resection of the residual cystic bile duct with gallbladder, and hepaticojejunostomy in Roux-en-Y fashion. As she approached the age of 63, her computed tomography scan showed no liver tumors. In the following year, she developed cholangiocarcinoma at the porta hepatis and underwent chemotherapy. However, the cancer progressed, and she died before she reached the age of 64 years. Conclusions Cholangiocarcinoma is extremely rare in patients with biliary atresia. However, physicians should follow up patients with biliary atresia as closely as possible, as malignant tumors secondary to biliary atresia may increase in number in the near future because of the growing number of long-term survivors with biliary atresia.


1993 ◽  
Vol 5 (1) ◽  
pp. 29-38 ◽  
Author(s):  
FA Van Assche

Major progress has been made in the knowledge and management of diabetes and pregnancy. However diabetes in pregnancy remains an important medical complication, with implications for mother and child in both the short and the long term. There are still controversies concerning the diagnostic criteria of gestational diabetes and concerning the best strategry for the treatment of this disorder. There is even less agreement about whether gestational diabetes is a pathological condition. The perinatal mortality in gestational diabetes has recently become as low as that in the general population. This has led to the conclusion that gestational diabetes is no more than a variant of metabolic adaptation during pregnancy. However, fetal hyperinsulinism is present in gestational diabetes, resulting in macrosomia, neonatal complications and most probably long term consequences. Improvements in the care of the preexisting insulin-dependent pregnant diabetic have been achieved but further progress in understanding the underlying mechanisms and in preventing and treating the disease are important goals for the near future.


Blood ◽  
2014 ◽  
Vol 124 (3) ◽  
pp. 363-373 ◽  
Author(s):  
Shernan G. Holtan ◽  
Marcelo Pasquini ◽  
Daniel J. Weisdorf

Abstract Over the past 5 years, many novel approaches to early diagnosis, prevention, and treatment of acute graft-versus-host disease (aGVHD) have been translated from the bench to the bedside. In this review, we highlight recent discoveries in the context of current aGVHD care. The most significant innovations that have already reached the clinic are prophylaxis strategies based upon a refinement of our understanding of key sensors, effectors, suppressors of the immune alloreactive response, and the resultant tissue damage from the aGVHD inflammatory cascade. In the near future, aGVHD prevention and treatment will likely involve multiple modalities, including small molecules regulating immunologic checkpoints, enhancement of suppressor cytokines and cellular subsets, modulation of the microbiota, graft manipulation, and other donor-based prophylaxis strategies. Despite long-term efforts, major challenges in treatment of established aGVHD still remain. Resolution of inflammation and facilitation of rapid immune reconstitution in those with only a limited response to corticosteroids is a research arena that remains rife with opportunity and urgent clinical need.


1976 ◽  
Vol 21 (3) ◽  
pp. 139-148 ◽  
Author(s):  
C. D. Marsden

The treatment of Parkinson's disease today is complex, time-consuming, but rewarding. The introduction of levodopa has not cured the disease, but has provided the most powerful therapy available yet. Its use is limited by side effects and careful titration to optimum dosage, often in combination with other drugs, is required. Despite best therapy, some patients never respond, and others begin to lose benefit after some years of therapy. New problems, such as the ‘on-off’ effect have appeared with long-term treatment, and require careful adjustment of dosage. As with any replacement therapy, a balance between sub-optimal benefit and side effects has to be discovered and maintained by careful and frequent review. New approaches to treatment may offer further improvement in the near future.


1998 ◽  
Vol 4 (4) ◽  
pp. 188-196 ◽  
Author(s):  
Gethin Morgan ◽  
Carole Buckley ◽  
Mike Nowers

The clinical assessment and management of suicide risk depends primarily on face to face contact with the individual who presents the risk, and aims to predict behaviour in the very near future. Whether or not clinical intervention prevents suicide depends a great deal on the clinician's skill in reaching out to the individual patient. This poses a dilemma, because much of what has been written about predicting suicide has been based on averaged data concerning long-term outcome in large cohorts of patients.


2017 ◽  
Author(s):  
Jason T. Wright ◽  
Michael P. Oman-Reagan

We discuss how visions for the futures of humanity in space and SETI are intertwined, and are shaped by prior work in the fields and by science fiction. This appears in the language used in the fields, and in the sometimes implicit assumptions made in discussions of them. We give examples from articulations of the so-called Fermi Paradox, discussions of the settlement of the Solar System (in the near future) and the Galaxy (in the far future), and METI. We argue that science fiction, especially the campy variety, is a significant contributor to the ‘giggle factor’ that hinders serious discussion and funding for SETI and Solar System settlement projects. We argue that humanity's long-term future in space will be shaped by our short-term visions for who goes there and how. Because of the way they entered the fields, we recommend avoiding the term ‘colony’ and its cognates when discussing the settlement of space, as well as other terms with similar pedigrees. We offer examples of science fiction and other writing that broaden and challenge our visions of human futures in space and SETI. In an appendix, we use an analogy with the well-funded and relatively uncontroversial searches for the dark matter particle to argue that SETI's lack of funding in the national science portfolio is primarily a problem of perception, not inherent merit.Also on arXiv: https://arxiv.org/abs/1708.05318Please cite this version:Wright, Jason T., and Michael P. Oman-Reagan. “Visions of Human Futures in Space and SETI.” International Journal of Astrobiology, 2017, 1–12. doi:10.1017/S1473550417000222.


2017 ◽  
Author(s):  
Homayoun Fathollahzadeh ◽  
Fabio Kaczala ◽  
Amit Bhatnagar ◽  
William Hogland

The main dilemma of contaminated sediments has been the proper management with reduced environmental footprints. Furthermore, by considering the fact that global warming and climate change may complicate the choice of management options, finding appropriate solutions become extremely critical. In the present work, mining of contaminated sediments to recover valuable constituents such as metals and nutrients is proposed as sustainable strategy, both through enhancing resilience of ecosystem and remediation. Contaminated sediments in the Oskarshamn harbor, southeast of Sweden were collected and analyzed through a modified sequential extraction in order to evaluate the feasibility of metals recovery. The results have shown that among different metals present in the sediments, Cu and Pb can be initially considered as economically feasible to recover. The shifting in the concept of dredging and further remediation of contaminated sediments towards sediment mining and recover of valuable metals can be considered in the near future as a sustainable strategy to tackle contaminated harbor/ports areas. However, it must be highlighted that short and long-term environmental impacts related to such activities should be addressed.


2021 ◽  
pp. 1-27
Author(s):  
Yichen Bao ◽  
Kai Liu ◽  
Quan Zheng ◽  
Lulu Yao ◽  
Yufu Xu

Abstract Pickering emulsion is a new type of stable emulsion made by ultra-fine solid particles instead of traditional surfactants as stabilizers, which has received widespread attention in recent years. The preparation methods of stator-rotor homogenization, high-pressure homogenization, and ultrasonic emulsification were compared with others in this work. The main factors affecting the stability of Pickering emulsion are the surface humidity of the solid particles, the polarity of the oil phase, and the oil-water ratio. These factors could affect the nature of the solid particles, the preparation process of Pickering emulsion and the external environment. Consequently, the long-term stability of Pickering emulsion is still a challenge. The tribological investigations of Pickering emulsion were summarized, and the multifunctional Pickering emulsion shows superior prospects for tribological applications. Moreover, the latest development of Pickering emulsion offers a new strategy for smart lubrication in the near future.


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