scholarly journals The use of a freeze-dried extract of Ligusticum mutellina in a cosmetic cream with potential antioxidant properties

2016 ◽  
Vol 29 (4) ◽  
pp. 155-157
Author(s):  
Baj Tomasz ◽  
Sieniawska Elwira ◽  
Kubiak Bartłomiej ◽  
Partyka Danuta
Keyword(s):  
Phenolic Acids ◽  
Antioxidant Properties ◽  
Polyphenolic Compounds ◽  
Release Profile ◽  
Qualitative Composition ◽  
Active Compounds ◽  
Cream Formulation ◽  
Freeze Dried ◽  
Dried Extract

Abstract The aim of this work was to develop a cream formulation with potential antioxidant properties. Herein, a freeze-dried extract of Ligusticum mutellina was used as a source of active compounds. The proposed qualitative composition of the cream was characterized by a good polyphenolic compounds release profile. Of note, the highest R2adj values were obtained for the Korsmeyer-Peppas and Higuchi models (0.9159 and 0.9226, respectively). These results indicate that a freeze-dried extract of L. mutellina, due to its retained high phenolic acids content, could become a key component in antioxidant creams.

scholarly journals Influence of Production Parameters on the Content of Polyphenolic Compounds in Extruded Porridge Enriched with Chokeberry Fruit (Aronia melanocarpa (Michx.) Elliott)

2019 ◽  
Vol 17 (1) ◽  
pp. 166-176 ◽  
Author(s):  
Tomasz Oniszczuk ◽  
Gabriela Widelska ◽  
Anna Oniszczuk ◽  
Kamila Kasprzak ◽  
Agnieszka Wójtowicz ◽  
...  
Keyword(s):  
Phenolic Acids ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
Extrusion Process ◽  
Polyphenolic Compounds ◽  
Production Parameters ◽  
Aronia Melanocarpa ◽  
Beneficial Impact ◽  
Free Phenolic Acids ◽  
Different Content

AbstractChokeberry fruit (Aronia melanocarpa (Michx.) Elliott) is known for its antioxidant properties and generally beneficial impact on human health. The aim of the research was to produce innovative corn porridge with a different content of chokeberry fruit percentage-wise and to test it to determine the content of polyphenolic compounds, including flavonoids and individual free phenolic acids, and determine the antioxidant properties of analysed extracts. One of the objectives was also to identify the optimum porridge production parameters, including, among other things, the rotational speed of the extruder screw during the extrusion process.Obtained results showed that an increased content of chokeberry fruit in porridge enhances its antioxidant properties, as well the content of polyphenols, flavonoids, and free phenolic acids. The greatest free radicals scavenging activity by all extracts was reported after 10 minutes of the process. The results of the above study demonstrate that extruded porridge enriched with chokeberry fruit have a potential for becoming a good source of natural antioxidants, and the extrusion process at 80 rpm does not degrade the tested active compounds.

scholarly journals Chemical profile and antioxidant activity of Trollius europaeus under the influence of feeding aphids

2018 ◽  
Vol 13 (1) ◽  
pp. 312-318 ◽  
Author(s):  
Ewa Witkowska-Banaszczak ◽  
Dominika Radzikowska ◽  
Karolina Ratajczak
Keyword(s):  
Antioxidant Activity ◽  
Chlorophyll Fluorescence ◽  
Phenolic Acids ◽  
Stress Level ◽  
Biotic Stress ◽  
Polyphenolic Compounds ◽  
Stress Factors ◽  
Chemical Profile ◽  
Active Compounds ◽  
Trollius Europaeus

AbstractThe influence of stress factors on a plant may lead to worse functioning of the plant and the loss of its crop. The effect of Aulacorthum solani feeding on Trollius europaeus with regard to active compounds in the leaves was investigated in the study. The antioxidant activity of the leaves, the material on which the insects fed, was compared with that of the material that was not infested by the aphids. Stress level was evaluated on the basis of such physiological parameters as chlorophyll fluorescence and photosynthesis activity. An increase of 34.5% in the content of polyphenolic compounds, as compared to control, was demonstrated in the material exposed to the biotic stress caused by aphids. The content of phenolic acids was 28% higher while that of flavonoids rose by 25%. The increase in polyphenolic compounds augmented the antioxidant activity of the material.

scholarly journals Content of Phenolic Compounds and Antioxidant Activity of New Gluten-Free Pasta with the Addition of Chestnut Flour

Molecules ◽  
2019 ◽  
Vol 24 (14) ◽  
pp. 2623 ◽  
Author(s):  
Oniszczuk ◽  
Widelska ◽  
Wójtowicz ◽  
Oniszczuk ◽  
Wojtunik-Kulesza ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Acids ◽  
Unsaturated Fatty Acids ◽  
Antioxidant Properties ◽  
Polyphenolic Compounds ◽  
Field Bean ◽  
Gluten Free ◽  
Total Polyphenols ◽  
Free Phenolic Acids ◽  
Chestnut Flour

Chestnut fruit abounds in carbohydrates, proteins, unsaturated fatty acids, fiber, polyphenolic compounds, as well as vitamins and micronutrients, that are behind the health-promoting properties of this plant. The purpose of the discussed research was to obtain innovative gluten-free pasta from rice and field bean flour enriched with a various addition of chestnut flour. Regarding the studied pasta, the following were determined: the content of free phenolic acids, total polyphenols, and antioxidant properties. Chromatographic analysis (HPLC-ESI-MS/MS (high-performance liquid chromatography-electrospray ionization tandem mass spectrometry)) revealed a wide variety of phenolic acids. In a sample with 20% and higher content of chestnut flour, as many as 13 acids were detected. Isoferulic acid prevailed. The total content of free phenolic acids and total polyphenols increased along with the increasing chestnut content. Moreover, in most cases, the content of individual acids increased with the addition of chestnut flour. Besides, the antioxidant activity was positively correlated with the addition of chestnut fruit flour, the content of free phenolic acids, and total polyphenols. Our research has demonstrated that our innovative gluten-free pasta, with the addition of chestnut flour, has a potential to be a source of polyphenolic compounds, including free phenolic acids, that are valuable for human health.

scholarly journals Antigenotoxic, Anti-photogenotoxic, and Antioxidant Properties of Polyscias filicifolia Shoots Cultivated In Vitro

Molecules ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 1090
Author(s):  
Ramona Figat ◽  
Anita Śliwińska ◽  
Anna Stochmal ◽  
Agata Soluch ◽  
Magdalena Sobczak ◽  
...  
Keyword(s):  
Phenolic Acids ◽  
Antioxidant Properties ◽  
Metabolic Activation ◽  
Biologically Active ◽  
Antimutagenic Activity ◽  
Active Compounds ◽  
Triterpenoid Saponins ◽  
Uva Irradiation ◽  
Wide Range

Traditional medicinal plants are an important source of active compounds with potential antimutagenic activity. Polyscias filicifolia Bailey (Araliaceae) is a South Asian traditional herb used as an adaptogenic and cardiac drug. Extracts of P. filicifolia contain a wide range of biologically active compounds like phenolic acids and triterpenoid saponins. In the present study. antigenotoxic potential of three naturally occurring phenolic acids and extracts of P. filicifolia growing in vitro with the addition of elicitors was evaluated against direct (4-nitroquinoline-N-oxide (4NQO) and mitomycin C (MMC)) and indirect mutagens (2-aminoanthracene (2AA)). The evaluation was made using a bacterial umu-test. Moreover, the ability to prevent photogenotoxicity induced by chlorpromazine (CPZ) under UVA irradiation was measured. The phytochemical profiling of examined extracts revealed the presence of numerous compounds with the prevelance of chlorogenic, caffeic, and ferulic acid derivatives; however, saponin fractions were also determined. The antioxidant potential of extracts strictly correlated with their composition. The tested extracts exhibited high antigenotoxic activity if the assay was performed with 2AA and metabolic activation. Moreover, the extracts slightly decreased the MMC-induced genotoxicity. However, an increase of the genotoxic effect was observed in the assay performed with 4NQO. In addition, photo-antigenotoxic activity was observed. In our study, phenolic acids exhibited lower activity than the extracts.

scholarly journals Application of freeze-dried Yarrowia lipolytica biomass in the synthesis of lipophilic antioxidants

2020 ◽  
Author(s):  
Bartłomiej Zieniuk ◽  
Małgorzata Wołoszynowska ◽  
Ewa Białecka-Florjańczyk ◽  
Agata Fabiszewska
Keyword(s):  
Phenolic Acids ◽  
Phenylacetic Acid ◽  
Food Additives ◽  
Antioxidant Properties ◽  
Enzymatic Esterification ◽  
Butyl Esters ◽  
Chemical Structures ◽  
Freeze Dried ◽  
Food Matrices ◽  
Acid Esters

Abstract Objective The aim of the study was to evaluate the possibility of using Y. lipolytica biomass as a whole-cell catalyst in the synthesis of lipophilic antioxidants, with the example of esterification of five phenolic acids with 1-butanol. Results Freeze-dried Y. lipolytica biomass was successfully applied as a biocatalyst in the synthesis of esters of phenylpropanoic acid derivatives with 75–98% conversion. However, in the case of phenylacetic acid derivatives, results below 10% were obtained. The biological activity of phenolic acid esters was strongly associated with their chemical structures. Butyl 3-(4-hydroxyphenyl)propanoate showed an IC50 value of 19 mg/ml (95 mM) and TEAC value of 0.427. Among the compounds tested, butyl esters of 3-(4-hydroxyphenyl)propanoic and 4-hydroxyphenylacetic acids exhibited the highest antifungal activity. Conclusions Lipophilization of phenolic acids achieved by enzymatic esterification creates prospects for using these compounds as food additives with antioxidant properties in lipid-rich food matrices.

scholarly journals Dehydrated at Different Conditions and Powdered Leek as a Concentrate of Biologically Active Substances: Antioxidant Activity and Phenolic Compound Profile

Materials ◽  
2021 ◽  
Vol 14 (20) ◽  
pp. 6127
Author(s):  
Beata Biernacka ◽  
Dariusz Dziki ◽  
Joanna Kozłowska ◽  
Iwona Kowalska ◽  
Agata Soluch
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Acids ◽  
Phenolic Acid ◽  
Antioxidant Properties ◽  
Biologically Active ◽  
Total Phenolic ◽  
Similar Degree ◽  
Allium Porrum ◽  
Drying Temperature ◽  
Freeze Dried

This study aimed to analyze the antioxidant activity, phenolic acid profile, color changes, and chemical composition of dried and powdered leek (Allium porrum). Leek was divided into white shaft (WH) and green shaft (GR) and subjected to drying by different methods—convection drying, vacuum drying, and freeze-drying (FD)—at a temperature of 60 °C. A sample freeze-dried at a temperature of 20 °C was used as control. Analyses of the dried leek samples revealed that GR contained a higher amount of ash, protein, fat, fiber, phenolic acids, and flavonoids, and exhibited higher antioxidant capacity compared to WH. The dominant phenolic acid in WH was p-cumaric acid followed by synapic and protocatechuic acids. GR had a several-fold higher content of phenolic acids than WH, with ferulic acid being dominant (about 85% of the total phenolic content). It was also observed that a higher drying temperature resulted in the degradation of phenolic compounds and reduced the antioxidant properties of leek shafts. Most importantly, FD under a temperature of 60 °C caused a similar degree of degradation of biologically active compounds as air drying. An increase in drying temperature was associated with a slight decrease in the lightness of GR, whereas in the case of WH no significant change in this parameter was observed.

Formulation and Evaluation of Polyherbal Cream Containing Cinnamomum zeylanicum Blume, Glycyrrhiza glabra L and Azadirachta indica A. Juss. Extracts to Topical Use

2020 ◽  
Vol 25 (2) ◽  
pp. 61-71
Author(s):  
Rajendra Gyawali ◽  
Rupesh Kumar Gupta ◽  
Sahana Shrestha ◽  
Rajendra Joshi ◽  
Prem Narayan Paudel
Keyword(s):  
Azadirachta Indica ◽  
Antioxidant Properties ◽  
Flow Property ◽  
Antioxidant Property ◽  
Glycyrrhiza Glabra ◽  
Cinnamomum Zeylanicum ◽  
Cream Formulation ◽  
Glycyrrhiza Glabra L ◽  
Lipid Peroxidase ◽  
Dpph Scavenging

Alcoholic extracts of medicinal plants Cinnamomum zeylanicum Blume, Glycyrrhiza glabra L, and Azadirachta indica A. Juss were subjected to the evaluation of antioxidant properties and combined for the cream formulation. The antioxidant property was determined by using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay and inhibition of lipid peroxidase assays. The cream formulation was designed using Minitab software and a central composite design was used to study the effect of dependent variables, steric acid and cetyl alcohol on the response variables such as, viscosity, pH, and spreadability. The phytochemical screening of extracts showed the presence of tannin, phenol, flavonoids, saponins, and alkaloids. Antioxidant properties of the extracts and their relative composition were found variable. Composition F3 (C. zeylanicum Blume: G. glabra L: A. indica A. Juss; 01: 02: 01) possessed the highest antioxidant capacity compared to other ratios. The cream prepared from this composition was found stable for pH, viscosity as well as antioxidant activity under normal condition (25) and accelerated condition (40 ). The cream with DPPH scavenging activity of 93.86 % at 15 µg/mL (IC50 8.58±0.30) and lipid peroxidase assay 90.93 % at 200 µg/mL (IC50 72.30±0.60) with pH 5.50 was found with a non-Newtonian positive thixotropic flow property. Parameters like pH, viscosity, and spreadability of the cream were within the acceptance range, and found stable and permeable

HPLC Screening of Bioactives Compounds and Antioxidant Capacity of Different Hypericum Species

2018 ◽  
Vol 69 (2) ◽  
pp. 305-309 ◽  
Author(s):  
Daniela Gitea ◽  
Simona Vicas ◽  
Manuel Alexandru Gitea ◽  
Sebastian Nemeth ◽  
Delia Mirela Tit ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Methanol Extract ◽  
Antioxidant Properties ◽  
Polyphenolic Compounds ◽  
The Other ◽  
The North ◽  
Western Area ◽  
North Western ◽  
Hypericum Species ◽  
Biological Actions

Our study compares the content in polyphenolic compounds and hypericin, in four species of Hypericum - H. perforatum L., H. maculatum Cr., H. hirsutum L., H. tetrapterum Fr. (syn. Hypericumacutum Mnch.) harvested from spontaneous flora in the north-western area of Transylvania, Romania. These species represent an important source of such compounds with different biological actions. After making the extracts, they were subjected to HPLC-SM analysis. The presence of rutoside in the largest amount (462.82 mg %) in the H. perforatum extract was observed, this containing most of the flavonoid heterosides. For the species H. maculatum, the presence in a much higher amount of the hyperoside (976.36 mg %) is characteristic compared to the other species. Quercetol is the best represented of the flavonoid aglycons, its concentration being the highest in H. hirsutum (659.66 mg %). The hypericin content ranges from 0.2171 g % in the H. tetrapterum extract, to 0.0314 g % in the methanol extract of H. maculatum.The highest antioxidant properties measured by FRAP method were recorded in the case of H. perforatum and H. maculatum.

Flavones and Their Analogues as Bioactive Compounds – An Overview

2019 ◽  
Vol 16 (4) ◽  
pp. 377-391 ◽  
Author(s):  
B.S. Jayashree ◽  
H. Venkatachalam ◽  
Sanchari Basu Mallik
Keyword(s):  
Biological Activity ◽  
Free Radical ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Cost Effective ◽  
Free Radical Scavenging ◽  
Polyphenolic Compounds ◽  
Pharmacological Activities ◽  
Poor Solubility

Flavonoids constitute a large group of polyphenolic compounds that are known to have antioxidant properties, through their free radical scavenging abilities. They possess a chromone (γ- benzopyrone) moiety, responsible for eliciting many pharmacological activities. Even though, natural flavonoids are highly potent, owing to their poor solubility, they are less used. Therefore, attempts have been made to improve their stability, solubility, efficacy and kinetics by introducing various substituents on the flavone ring. For nearly the last two decades, flavones were synthesized in our laboratory by simple, convenient and cost-effective methods, with the knowledge of both synthetic and semi-synthetic chemistry. In this direction, it was considered worthwhile to present an overview on the synthesized flavonoids. This review creates a platform for highlighting various modifications done on the flavone system along with their biological activity.

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