scholarly journals Anthropogenic Transformation of the Vegetation in the Immediate Vicinity of the Settlement Complex at Poganowo (Mrągowo Lakeland, Ne Poland)

2015 ◽  
Vol 32 (1) ◽  
pp. 19-29 ◽  
Author(s):  
Marta Szal ◽  
Mirosława Kupryjanowicz ◽  
Mariusz Wyczółkowski

Abstract The results of pollen, non-pollen palynomorph and microcharcoal particle analyses of deposits from a small pond in north eastern Poland are presented. The study focused on human-induced vegetation changes that occurred in a close vicinity of the settlement complex at Poganowo during the Middle Ages (ca 10th-16th centuries). We distinguished three phases of human impact. First and third phases correspond to intensified settlement activity. The second phase was a period when human activity decreased and woodland regeneration took place. The high incidence of the parasitic fungus Kretzschmaria deusta in a local forest stand during the third phase was simultaneous with numerous spores of coprophilous fungi (Sordaria-type and Cercophora-type). We consider that Kretzschmaria deusta inhabited the roots and bases of tree trunks damaged by digging and grazing animals.

2020 ◽  
Vol 5 (1) ◽  
pp. 234-243
Author(s):  
Kamal Azmi Abd. Rahman ◽  
Indriaty Ismail

Miskawayh is an important figure in the development of Islamic ethical philosophy. The synthesis between Greek philosophy and Islamic knowledge which he developed in the Middle Ages is considered a significant innovation in the formation of Islamic ethical philosophy. Miskawayh’s scholarship can be seen in his career commitment and in academic circles during his stay in his hometown Rayy and Baghdad. Though Miskawayh’s biography has been widely presented, his biographical narrative in this study is needed to ascertain his life changes based on different phases of his life. Therefore, this qualitative study will discuss the biography of Miskawayh. A biographical narrative analysis of Miskawayh found four major phases in his life. The first phase (up until the age of about 20) was when he obtained basic Islamic knowledge and studied chemistry. The second phase was between 956 AD and 963 AD in Baghdad. During that period of time, he was involved in the discussion of philosophy and dealing with moral issues. The third phase was in 963 AD in Rayy, Iran, where he dedicated his time studying various themes of writing and teaching. The fourth phase was between 976 AD and 1030 AD, at the age of 44 until his death at the age of 96 in Iṣfahān, Iran. During this phase, he was active in philosophical writings and refining ethics. Due to the breadth of Miskawayh’s knowledge and experience, his writings on ethics have been influential, especially his magnum opus entitled Tahdhīb al-Akhlāq that has received a substantial amount of attention from the Islamic and Western scholars to this day. This work written to the end of Miskawayh’s life proved his scholarly interest in philosophy, self-development, and career. ABSTRAK  Miskawayh merupakan seorang tokoh penting dalam perkembangan ilmu falsafah akhlak. Sintesis falsafah Yunani dengan ilmu Islam yang telah dilakukan oleh beliau pada abad pertengahan dianggap sebagai suatu inovasi yang signifikan dalam pembentukan ilmu akhlak Islam. Kesarjanaan Miskawayh boleh dilihat melalui komitmennya terhadap kerjaya dan dunia akademik sepanjang beliau berada di Rayy, Iran kota kelahirannya dan juga ketika berada di Baghdad. Walaupun biografi Miskawayh telah banyak dibentangkan, naratif biografi beliau di dalam kajian ini diperlukan bagi mengenal pasti perubahan hidup Miskawayh berdasarkan kepada fasa kehidupannya yang berbeza. Oleh itu, kajian berbentuk kualitatif ini akan membahaskan tentang biografi Miskawayh. Analisis naratif terhadap biografi tersebut mendapati bahawa Miskawayh telah melalui empat fasa penting dalam kehidupannya. Fasa pertama (sehingga usiannya kira-kira 20 tahun) ialah ketika beliau mendapatkan ilmu asas Islam dan mempelajari tentang ilmu kimia. Fasa kedua ialah antara 956 sehingga 963 Masihi di Baghdad. Ketika ini beliau terlibat dengan perbincangan falsafah dan berhadapan dengan masalah akhlak. Fasa ketiga pula ialah pada tahun 963 Masihi di Rayy, Iran di mana beliau telah mendedikasikan masanya untuk menelaah pelbagai tema penulisan dan mengajar. Fasa yang keempat ialah pada 976 Masihi iaitu ketika usianya mencecah 44 tahun sehingga beliau meninggal dunia pada 1030 Masihi pada usia 96 tahun di Iṣfahān, Iran. Pada fasa ini, beliau aktif dalam penulisan falsafah dan melakukan mujahadah dalam akhlak. Oleh kerana keluasan ilmu dan pengalaman yang telah dilalui oleh Miskawayh dalam empat fasa ini, penulisan beliau tentang akhlak terutamanya di dalam magnum opus yang bertajuk Tahdhīb al-Akhlāq menjadi sebuah karya yang berpengaruh dan mendapat perhatian pengkaji Islam dan Barat sehingga kini. Karya yang telah ditulis di penghujung hayat Miskawayh ini telah membuktikan kesarjanaan beliau dalam ilmu falsafah, hal pembangunan kendiri serta kerjaya.  


2013 ◽  
Vol 5 (1) ◽  
Author(s):  
Abdul Hasan Saragih

This classroom research was conducted on the autocad instructions to the first grade of mechinary class of SMK Negeri 1 Stabat aiming at : (1) improving the student’ archievementon autocad instructional to the student of mechinary architecture class of SMK Negeri 1 Stabat, (2) applying Quantum Learning Model to the students of mechinary class of SMK Negeri 1 Stabat, arising the positive response to autocad subject by applying Quantum Learning Model of the students of mechinary class of SMK Negeri 1 Stabat. The result shows that (1) by applying quantum learning model, the students’ achievement improves significantly. The improvement ofthe achievement of the 34 students is very satisfactory; on the first phase, 27 students passed (70.59%), 10 students failed (29.41%). On the second phase 27 students (79.41%) passed and 7 students (20.59%) failed. On the third phase 30 students (88.24%) passed and 4 students (11.76%) failed. The application of quantum learning model in SMK Negeri 1 Stabat proved satisfying. This was visible from the activeness of the students from phase 1 to 3. The activeness average of the students was 74.31% on phase 1,81.35% on phase 2, and 83.63% on phase 3. (3) The application of the quantum learning model on teaching autocad was very positively welcome by the students of mechinary class of SMK Negeri 1 Stabat. On phase 1 the improvement was 81.53% . It improved to 86.15% on phase 3. Therefore, The improvement ofstudent’ response can be categorized good.


2020 ◽  
Author(s):  
Adriana Klein ◽  
Roseli de Deus Lopes ◽  
Rodrigo Suigh

BACKGROUND EasySeating is a mobile health (mHealth) app that supports the prescription of wheelchair and postural support devices (WPSD). It can be used by occupational therapists (OT) and physiotherapists (PT) who prescribe WPSD. The app offers a standardization of the prescription procedure, showing images, metrics and details that guide the prescriber to decide on the best equipment. It was developed with an iterative mixed-methods evaluation approach. Objective: The aim of this study was to investigate the processes involved in the prescription of WPSD and to propose, develop and evaluate a mHealth to support OT and PT prescribers. OBJECTIVE The aim of this study was to investigate the processes involved in the prescription of WPSD and to propose, develop and evaluate a mHealth to support OT and PT prescribers. METHODS This study was divided into three phases and was carried out as an iterative process composed of user consulting/testing (using a mixed-methods evaluation approach), system (re)design and software development. The first phase consisted of the collection of qualitative and quantitative data to map and understand the users requirements and of the development of the first prototype (v1) of the app. This data collection was performed through semi-structured interviews with 14 OT and PT prescribers, 5 specialized technicians and 5 WPSD users. The second phase aimed at improving the overall functionality of the app and consisted in the development, test and evaluation of the prototypes v1, v2, v3 and v4. A total of 59 prescribers tested and evaluated these prototypes by means of open interviews, semi-structured questionnaires and focus groups. The third phase focused in the usability aspects of the app. It consisted in the development and test of the prototype v5. Eight technology specialists assessed its usability through heuristics evaluation. RESULTS Data collected in phase one indicated there is a lack of standardization on the prescription of postural support devices (PSD). A divergent nomenclature for the PSDs was also found and classified in eight categories. These information guided the development of the first prototype of the EasySeating app. Phase two results pointed that the prescribers value the insertion of the app into their clinical practice, as it accelerates and increases the quality of the evaluation process and improves the organization of the prescription information. Significant suggestions for the improvement of the app were given during the users tests, including the use of images to represent the PSDs. The usability tests from the third phase revealed two strong issues that must be solved: the need of greater feedback and failures in the persistence of the input data. CONCLUSIONS This study demonstrated that there is a lack of systematization of the WPSD prescription process. The evaluation of the developed EasySeating app demonstrated that there is a potential to standardize, integrate and organize the WPSD prescription information, supporting and facilitating the decision making process of the prescribers. CLINICALTRIAL This study was approved by the Research Ethics Board of the Universidade de São Paulo (registered protocol n°53929516.6.0000.0065) URL - http://plataformabrasil.saude.gov.br/login.jsf


2019 ◽  
Vol 29 (2) ◽  
pp. 104-125

Three phases in Foucault’s examination of authorship and free speech were essential to him throughout his life. They can be linked to such texts as the three lectures “What is an Author?” (first phase), “What is Critique?,” and “What is Revolution?” (second phase), and the two lecture courses, “Fearless Speech,” and “The Courage of Truth” (third phase). Initially, Foucault merely describes the founders of discursivity (hence, “superauthors”), among whom he reckoned only Marx and Freud, as the sole alternative to his own conceptualization of the author function, which is exhibited en masse in contemporary society. He then modifies his views on superauthorship by making Kant the paradigm and by linking his own concept of free speech to a Kan-tian critical attitude. However, Foucault claims only the half of Kant’s philosophical legacy that is related to the study of the ontology of the self.The article advances the hypothesis that the sovereign power of speech, which can be found in Marx and Heidegger and in generally in the concept of “superauthorship,” becomes unacceptable for Foucault. During the third phase, the danger of a tyrannical use of free speech compels Foucault to make a number of fruitful but questionable choices in his work. He focuses on a single aspect of free speech in which a speaker is in a weaker position and therefore has to overcome his fear in order to tell the truth. Foucault associates this kind of free speech with the ancient Greek notion of parrhesia, which according to his interpretation means “fearless speech”; however, this reading is not always supported by the ancient Greek sources. Foucault’s deliberations bring him to the radical conclusion that free speech transforms into performative “aesthetics of existence.” Foucault’s main motivation for pursuing this line of thought all through his life was to investigate his own abilities and powers as an author


Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1007
Author(s):  
Jiří Gregor ◽  
Kateřina Radilová ◽  
Jiří Brynda ◽  
Jindřich Fanfrlík ◽  
Jan Konvalinka ◽  
...  

Influenza A virus (IAV) encodes a polymerase composed of three subunits: PA, with endonuclease activity, PB1 with polymerase activity and PB2 with host RNA five-prime cap binding site. Their cooperation and stepwise activation include a process called cap-snatching, which is a crucial step in the IAV life cycle. Reproduction of IAV can be blocked by disrupting the interaction between the PB2 domain and the five-prime cap. An inhibitor of this interaction called pimodivir (VX-787) recently entered the third phase of clinical trial; however, several mutations in PB2 that cause resistance to pimodivir were observed. First major mutation, F404Y, causing resistance was identified during preclinical testing, next the mutation M431I was identified in patients during the second phase of clinical trials. The mutation H357N was identified during testing of IAV strains at Centers for Disease Control and Prevention. We set out to provide a structural and thermodynamic analysis of the interactions between cap-binding domain of PB2 wild-type and PB2 variants bearing these mutations and pimodivir. Here we present four crystal structures of PB2-WT, PB2-F404Y, PB2-M431I and PB2-H357N in complex with pimodivir. We have thermodynamically analysed all PB2 variants and proposed the effect of these mutations on thermodynamic parameters of these interactions and pimodivir resistance development. These data will contribute to understanding the effect of these missense mutations to the resistance development and help to design next generation inhibitors.


2021 ◽  
Vol 13 (01) ◽  
pp. 35-41
Author(s):  
Sunyarn Niempoog ◽  
Kiat Witoonchart ◽  
Woraphon Jaroenporn

AbstractModern hand surgery in Thailand started after the end of World War II. It is divided into 4 phases. In the initial phase (1950-1965), the surgery of the hand was mainly performed by general surgeons. In 1965-1975, which was the second phase, many plastic surgeons and orthopaedic surgeons graduated from foreign countries and came back to Thailand. They played a vital role in the treatment of the surgery of the hand and set up hand units in many centers. They also contributed to the establishment of the “Thai Society for Surgery of the Hand,” which still continues to operate. In the third phase (1975-2000), there was a dramatic development of microsurgery because of the rapid economic expansion. There were many replantation, free tissue transfers, and brachial plexus surgeries in traffic and factory-related accidents. The first hand-fellow training program began in 1993. In the fourth phase (since 2000), the number of hand injuries from factory-related accidents began declining. But the injury from traffic accidents had been increasing both in severity and number. Moreover, the diseases of hand that relate to aging and degeneration had been on the rise. Thai hand surgeons have been using several state-of-the-art technologies such as arthroscopic and endoscopic surgery. They are continuing to invent innovations, generating international publications, and frequently being invited as speakers in foreign countries.


2017 ◽  
Vol 52 (3) ◽  
pp. 377-398 ◽  
Author(s):  
John Coakley

This article explores the value of a specific model of norm replacement in accounting for the circumstances leading to Ireland’s Good Friday agreement (1998), which formally and finally settled the long-running territorial dispute between Ireland and the United Kingdom (UK). Drawing on the theoretical literature, it identifies three phases in this process. First, from the creation of the Irish Free State in 1922 until the civil unrest in Northern Ireland peaked in 1972 the irredentist norm was substantially unchallenged. It was embedded in the 1937 constitution, which defined the national territory as extending over the whole island of Ireland – including Northern Ireland, a part of the UK. The second phase, from about 1972 to 1998, was one of norm competition. The irredentist norm was severely challenged by new political realities in Northern Ireland, and was potentially destabilising for the state itself. It was increasingly challenged by an alternative ‘consent’ norm, one embracing in effect the geopolitical status quo. The third phase, from 1998 onwards, was one of consolidation of the new norm, now written into the Irish constitution to replace the wording of 1937. The article suggests that this model plays a valuable role in accounting for the changing status of the Irish border, but also that the Irish experience has implications for the broad shape of the model.


Author(s):  
Fernanda Berchelli Girão Miranda ◽  
Alessandra Mazzo ◽  
Gerson Alves Pereira-Junior

ABSTRACT Objective: to build and validate competency frameworks to be developed in the training of nurses for the care of adult patients in situations of emergency with a focus on airway, breathing and circulation approach. Method: this is a descriptive and methodological study that took place in three phases: the first phase consisted in a literature review and a workshop involving seven experts for the creation of the competency frameworks; in the second phase, 15 experts selected through the Snowball Technique and Delphi Technique participated in the face and content validation, with analysis of the content of the suggestions and calculation of the Content Validation Index to assess the agreement on the representativeness of each item; in the third phase, 13 experts participated in the final agreement of the presented material. Results: the majority of the experts were nurses, with graduation and professional experience in the theme of the study. Competency frameworks were developed and validated for the training of nurses in the airway, breathing and circulation approach. Conclusion: the study made it possible to build and validate competency frameworks. We highlight its originality and potentialities to guide teachers and researchers in an efficient and objective way in the practical development of skills involved in the subject approached.


Kybernetes ◽  
2018 ◽  
Vol 47 (8) ◽  
pp. 1664-1686 ◽  
Author(s):  
Cihan Çetinkaya ◽  
Mehmet Kabak ◽  
Mehmet Erbaş ◽  
Eren Özceylan

Purpose The aim of this study is to evaluate the potential geographic locations for ecotourism activities and to select the best one among alternatives. Design/methodology/approach The proposed model consists of four sequential phases. In the first phase, different geographic criteria are determined based on existing literature, and data are gathered using GIS. On equal criteria weighing, alternative locations are determined using GIS in the second phase. In the third phase, the identified criteria are weighted using analytical hierarchy process (AHP) by various stakeholders of potential ecotourism sites. In the fourth phase, the PROMETHEE method is applied to determine the best alternative based on the weighted criteria. Findings A framework including four sequential steps is proposed. Using real data from the Black Sea region in Turkey, the authors test the applicability of the evaluation approach and compare the best alternative obtained by the proposed method for nine cities in the region. Consequently, west of Sinop, east of Artvin and south of the Black Sea region are determined as very suitable locations for ecotourism. Research limitations/implications The first limitation of the study is considered the number of included criteria. Another limitation is the use of deterministic parameters that do not cope with uncertainty. Further research can be conducted for determining the optimum locations for different types of tourism, e.g. religion tourism, hunting tourism and golf tourism, for effective tourism planning. Practical implications The proposed approach can be applied to all area that cover the considered criteria. The approach has been tested in the Black Sea region (nine cities) in Turkey. Social implications Using the proposed approach, decision-makers can determine locations where environmentally responsible travel to natural areas to enjoy and appreciate nature that promotes conservation have a low visitor impact and provide for beneficially active socioeconomic involvement of local individuals. Originality/value To the best knowledge of the authors, this is the first study which applies a GIS-based multi-criteria decision-making approach for ecotourism site selection.


Author(s):  
Elīna Akmane ◽  
Kristīne Mārtinsone ◽  
Zane Krieķe ◽  
Viktorija Perepjolkina ◽  
Agnese Drunka ◽  
...  

The aim of this research was to develop multiscale questionnaire of professional identity (PI) and to test its psychometric properties. This research was conducted in 3 phases. During the first phase a scoping review, a focus group discussion, and a rapid literature review were conducted to identify the criteria of PI. Survey items were constructed and assessed in the second phase. The data were collected, and the psychometric properties were examined in the third phase. The survey was completed by 239 psychological help providers in Latvia (psychiatrists (n = 13), nurses (n = 37), psychotherapists (n = 8), art therapists (n = 45), psychologists (n = 55), psychotherapy specialists (n = 28) and social workers (n = 53)) aged between 22 and 80 years (M = 45.8; SD = 10.6) of which 95% women (n = 227) and 5% men (n = 12). As a result, 8 factors structure was confirmed (k = 38). Overall, it can be concluded that the survey examines a unified phenomenon, and the items are internally consistent on all scales (α = .715 - .873). The development of this questionnaire is an important step towards the research of PI.   


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