scholarly journals Contamination of the urban environment with excrements of companion animals as an underestimated source of Staphylococcus species posing a threat to public health

2020 ◽  
Vol 68 (1) ◽  
pp. 12-19
Author(s):  
Aleksandra Trościańczyk ◽  
Aneta Nowakiewicz ◽  
Sebastian Gnat ◽  
Magdalena Wójcik ◽  
Sylwia Wdowiak-Wróbel ◽  
...  
Keyword(s):  
Public Health ◽  
Gastrointestinal Tract ◽  
Urban Space ◽  
Potential Risk ◽  
Companion Animals ◽  
Individual Resistance ◽  
Phenotypic Resistance ◽  
Restriction Sites ◽  
High Level ◽  
Genotypic Characteristics

AbstractThe aim of the study was to assess the incidence, resistance, virulence, and genotypic characteristics of Staphylococcus spp. residing in the gastrointestinal tract of dogs and cats, as a group of animals causing potential contamination of the urban space. A high percentage of strains resistant to penicillin (58%), oxacillin (9%) and tetracycline (60%) were found. All isolates resistant to penicillin, kanamycin, or chloramphenicol carried genes responsible for individual resistance (blaZ, aph(3′)-IIIa, and cat (pC194)/cat (pC223), respectively. The mecA gene was detected in 45% of the oxacillin-resistant Staphylococcus pseudintermedius strains. The amplification of DNA fragments surrounding rare restriction sites analysis demonstrated high heterogeneity of genotypic profiles correlating with phenotypic resistance profiles. Multilocus sequence typing analysis classified the methicillin-resistant S. pseudintermedius strains as ST71, ST890, and the totally new ST1047. The presence of a high level of resistance among Staphylococcus strains may suggest a potential risk of transfer of these bacteria between companion animals and humans.

Developmental Disorders in Canada

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Sarah Palmeter
Keyword(s):  
Public Health ◽  
Developmental Disorders ◽  
Health Agency ◽  
The Public ◽  
Age Of Diagnosis ◽  
High Level ◽  
Project Objectives ◽  
Disability Severity ◽  
Occupational Function ◽  
Improve Health

In the completion of my practicum at the Public Health Agency of Canada (PHAC) this summer, I worked to develop a surveillance knowledge product to support the national surveillance of developmental disorders. This project used Statistics Canada’s 2017 Canadian Survey on Disability to investigate the burden of developmental disorders in Canada. Developmental disorders are conditions with onset in the developmental period. They are associated with developmental deficits and impairments of personal, social, academic, and occupational function. The project objectives are to estimate the prevalence of developmental disorders in Canadians 15 years of age or older, overall and by age and sex, as well as report on the age of diagnosis, disability severity, and disability co-occurrence in those with developmental disorders. The majority of the analysis has been completed and preliminary results completed, which cannot be released prior to PHAC publication. Although not highly prevalent, developmental disorders are associated with a high level of disability in young Canadians. Early detection and interventions have been shown to improve health and social outcomes among affected individuals. Understanding the burden of developmental disorders in Canada is essential to the development of public health policies and services.

ANTICYTOKINE ACTIVITY OF THE PROTOZOA BLASTOCYSTIS SPP

2020 ◽  
pp. 44-48
Author(s):  
Bugero N.V. ◽  
Ilyina N.A. ◽  
Aleksandrova S.M.
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Ulcer Disease ◽  
Cytokine Balance ◽  
High Prevalence ◽  
Blastocystis Spp ◽  
High Level ◽  
Eukaryotic Organisms ◽  
High Degree

In addition to the classical pathogens, which are well understood and well identified, new pathogens with the potential to spread epidemiologically are being identified. Some of these little-known organisms are the simplest Blastocystis spp. blastocystostosis. The clinical significance of Blastocystis spp. and its pathogenicity are still under discussion. This parasite belongs to a group of single-celled eukaryotic organisms living in the colon of the human intestine. Blastocystis spp. is known to be found both in people with reduced immune status and in individuals without any clinical manifestation. It has been established that a sufficiently high degree of invasiveness is observed in persons with gastrointestinal tract diseases, dermatosis, allergic reactions, in patients with carriers of the human immunodeficiency virus, etc. Possessing persistence factors, protozoa blastocysts contribute to the inactivation of host defensive mechanisms, providing a stable anthogonistic effect. In recent years, many works have been devoted to the characteristics of the persistent properties of Blastocystis spr., however, individual properties of blastocysts, in particular, anticytokine activity (ACA), have not yet been studied. In this regard, the work studied the anticytokine activity of microorganisms isolated from healthy subjects and patients with gastrointestinal tract diseases. A high prevalence of the studied characteristic in the subjects was shown. The expression of anticytokine activity in the obtained isolates of blastocysts was the highest in the group of persons with gastric ulcer disease, which decreased in the order of duodenal ulcer, chronic cholecystitis, chronic gastritis, etc. The data obtained in this work on the high level of ACA expression in blastocyst isolates obtained from individuals with gastrointestinal diseases as compared with the control group enables to conclude that their exometabolites may influence the local cytokine balance [1], which supports the inflammatory process.

scholarly journals Vaccination knowledge, attitudes and practices in patients with HIV: a cross-sectional survey

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S Rousset ◽  
G Voglino ◽  
E Boietti ◽  
A Corradi ◽  
M R Gualano ◽  
...  
Keyword(s):  
Public Health ◽  
Infectious Diseases ◽  
Health System ◽  
Vaccination Coverage ◽  
Public Health System ◽  
Cross Sectional Survey ◽  
Hiv Patients ◽  
Cross Sectional ◽  
Contagion Risk ◽  
High Level

Abstract Background Infectious diseases are more common and severe in patients with HIV, which show different response to vaccines and a diminished protection. It is therefore very important to assess knowledge and attitudes towards vaccination in people with HIV, since precise vaccination coverage and vaccine hesitancy are not well established in this subgroup of patients. Methods A sample of 119 patients with HIV completed a cross-sectional survey. Patients were recruited during their routine medical examination at the infectious diseases clinic in Turin. The survey explored these main areas: demographics and history of HIV infection, vaccination history, attitudes towards vaccination, confidence in the public health system, contagion risk and disease seriousness perception. In this preliminary phase descriptive analysis were conducted. Results Preliminary data show that mean age of the participants was 49.51 years, 80% were males. The median of HIV infection duration was 10 years, while the median of the lymphocyte count was 762.50 cells/mm3. The disease with the highest vaccination coverage was tetanus (88.7%), considered a serious or very serious disease by 85.6% of the participants, despite low or very low contagion risk perception (84.1%). The disease with the lowest vaccination coverage was Herpes Zoster (7.3%), despite high or very high seriousness perception (70%). Furthermore, 99.1% of the participants showed high or very high confidence toward public health system professionals, and the majority of them (59.5%) stated that vaccines are more useful for the community than for the single person. Conclusions Vaccination coverage is still not fully satisfactory regarding diseases considered infrequent or mild. Considering the high level of confidence toward the public health system that has emerged, it is necessary to implement informative and operative strategies about vaccination for European HIV patients, which are particularly at risk regarding infectious diseases. Key messages Vaccination coverage and risk perception in HIV patients is not satisfactory for many diseases and an effort to implement informative strategies in Europe is needed. The role of vaccination in preventing infectious diseases in HIV patients should be recognized and strengthened by relying on the high level of confidence toward European public health systems.

scholarly journals Spatial and Statistical Analysis of Urban Poverty for Sustainable City Development

2021 ◽  
Vol 13 (2) ◽  
pp. 858
Author(s):  
Wojciech Kisiała ◽  
Izabela Rącka
Keyword(s):  
Urban Space ◽  
Social Inequalities ◽  
Urban Poverty ◽  
Sustainable Urban Development ◽  
Social Aspect ◽  
City Development ◽  
Residential Properties ◽  
City Structure ◽  
High Level ◽  
The Impact

One of the main pillars of sustainable urban development at the local scale is to control the social aspect of urban equality of socio-economic systems. A number of studies confirm that poverty in urban space is accompanied by negative phenomena, such as high unemployment, social pathologies, increased crime rate, or the high level of the decapitalization of space, including the poor condition of housing and municipal infrastructure. However, there is a gap in defining the relation between urban poverty and city structure to control and preferably minimize social inequalities. The aim of the study was to empirically verify the impact of the location of residential properties in relation to poverty-stricken areas in the city. The research covered the housing market in one Polish city (Kalisz) in the years 2006–2018. By applying GIS technologies, we identified the location of each property in relation to poverty areas. The data was subjected to regression analysis, with the use of the hedonic approach based on exponential models. The analysis of data allowed us to conclude that location in a poorer area does affect the prices of new flats, which is not only a contribution to the development of science, but is also information that could be used by developers or property valuers to establish the prices of flats, as well as city managers to avoid pauperization of urban districts.

scholarly journals Snus and snus-like nicotine products moving across Nordic borders: Can laws protect young people?

2021 ◽  
pp. 145507252199570
Author(s):  
Marjut Salokannel ◽  
Eeva Ollila
Keyword(s):  
Public Health ◽  
Young People ◽  
Health Impact ◽  
The Public ◽  
European Court ◽  
Wide Availability ◽  
Personal Use ◽  
Health Studies ◽  
High Level ◽  
The Eu

Background: Use of snus and snus-like nicotine products is increasing, in particular among young people, in several Nordic countries and Estonia, while snus is legally on the market only in Sweden and Norway. Snus is available in a great variety of tastes and packaging particularly catering for young users. Recently, strong snus-resembling nicotine pouches have emerged on the market. This research investigates the regulatory means to counteract this development. Methods: European Union (EU) and national tobacco control legislation, case law of the European Court of Justice (CJEU) and relevant public health studies are analysed. Results: The research finds that the judgement of the CJEU relating to the sale of snus on Finnish ferries has not been enforced. Permitted large traveller imports for personal use have contributed to wide availability of snus in Finland. Even if the legislation in Sweden is in conformity with the exemption it obtained in the Accession Treaty, the public health impact of snus use for young people in its neighbouring countries has become considerable. Nicotine pouches, -which are not regarded as medical products in terms of medicine legislation, lack harmonised EU-wide regulation. Controlling smuggling across open borders is challenging. Conclusions: The legislation at the EU and national levels should be able to protect young people from new tobacco and nicotine products. It is urgent to harmonise regulation relating to new tobacco and nicotine products taking as a base a high level of protection of health as required in the Treaty on the Functioning of the EU.

Public health risk analysis of European bat lyssavirus infection in The Netherlands

2008 ◽  
Vol 137 (6) ◽  
pp. 803-809 ◽  
Author(s):  
K. TAKUMI ◽  
P. H. C. LINA ◽  
W. H. M. VAN DER POEL ◽  
J. A. KRAMPS ◽  
J. W. B. VAN DER GIESSEN
Keyword(s):  
Public Health ◽  
Risk Analysis ◽  
The Netherlands ◽  
Health Risk ◽  
Companion Animals ◽  
Public Health Risk ◽  
Northern Half ◽  
Viral Particles ◽  
Bat Rabies ◽  
Eptesicus Serotinus

SUMMARYWe present the frequency and the nature of contact incidents of the Serotine bat,Eptesicus serotinus, with humans and with companion animals (specifically cats and dogs), in The Netherlands between 2000 and 2005. Out of 17 bats in bite contact with humans, five tested positive for European bat lyssavirus (EBLV) type 1a. Cats had the most numerous contacts with bats (49 times) but a relatively low number of these bats were EBLV positive (six times). We estimated that the average incidence of human bat rabies infection might be between once per year and once per 700 years, depending mainly on the number of infectious viral particles in bat saliva. The risk of bat rabies is higher between April and October, and in the northern half of the country. This is the first study in Europe describing the risk of human bat rabies after bat contact incidents.

scholarly journals Does the possession of virulence factor genes mean that those genes will be active?

2009 ◽  
Vol 7 (S1) ◽  
pp. S19-S28 ◽  
Author(s):  
Stephen C. Edberg
Keyword(s):  
Public Health ◽  
Gastrointestinal Tract ◽  
Virulence Factors ◽  
Alimentary Tract ◽  
The Body ◽  
Normal Flora ◽  
Mucosal Surfaces ◽  
Stomach Acid ◽  
Specific Receptors ◽  
Virulence Factor Genes

There are a number of relationships the host can establish with the microbes we ingest. For the vast majority of microbes, they have a short-lived liaison with the human host. Either they are destroyed by the stomach acid or bile, or can not establish even a temporary residency in the gastrointestinal tract. Early in life the mucosal surfaces of the body establishes a resident, and generally stable, normal flora. These normal flora microbes, the majority of which are bacteria, have specific receptors for specific areas of the alimentary tract. If the foreign microbe can establish residency, it then may transiently or permanently become part of the normal flora. However, in order to produce disease, it must possess an additional set of virulence factors. While some of these are known, many are not. Those that are known include enzymes, such as protease, lipase, and esterase. Accordingly, VFAR may not be associated with human disease and its presence or absence has no public health meaning.

scholarly journals Molecular survey of mcr1 and mcr2 plasmid mediated colistin resistance genes in Escherichia coli isolates of animal origin in Iran

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Kayhan Ilbeigi ◽  
Mahdi Askari Badouei ◽  
Hossein Vaezi ◽  
Hassan Zaheri ◽  
Sina Aghasharif ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Resistance Genes ◽  
Companion Animals ◽  
Multidrug Resistant ◽  
Animal Origin ◽  
Colistin Resistance ◽  
E Coli ◽  
High Level ◽  
Farming Industry

Abstract Objectives The emergence of colistin-resistant Enterobacteriaceae from human and animal sources is one of the major public health concerns as colistin is the last-resort antibiotic for treating infections caused by multidrug-resistant Gram-negative bacteria. We aimed to determine the prevalence of the prototype widespread colistin resistance genes (mcr-1 and mcr-2) among commensal and pathogenic Escherichia coli strains isolated from food-producing and companion animals in Iran. Results A total of 607 E. coli isolates which were previously collected from different animal sources between 2008 and 2016 used to uncover the possible presence of plasmid-mediated colistin resistance genes (mcr-1 and mcr-2) by PCR. Overall, our results could not confirm the presence of any mcr-1 or mcr-2 positive E. coli among the studied isolates. It is concluded that despite the important role of food-producing animals in transferring the antibiotic resistance, they were not the main source for carriage of mcr-1 and mcr-2 in Iran until 2016. This study suggests that the other mcr variants (mcr-3 to mcr-9) might be responsible for conferring colistin resistance in animal isolates in Iran. The possible linkage between pig farming industry and high level of mcr carriage in some countries needs to be clarified in future prospective studies.

PUBLIC HEALTH, NURSING, MEDICAL SOCIAL WORK

PEDIATRICS ◽  
1957 ◽  
Vol 20 (6) ◽  
pp. 1095-1096
Keyword(s):  
Public Health ◽  
Health Service ◽  
Birth Rate ◽  
Public Health Service ◽  
Vital Statistics ◽  
Medical Social Work ◽  
National Office ◽  
Health Nursing ◽  
High Level ◽  
Monthly Variations

AS PART of its Monthly Vital Statistics Report, the National Office of Vital Statistics of the U. S. Public Health Service publishes each year an estimate of the most important statistical indices of the previous year. In the March 12, 1957 issue of the Report, Vol. 5, No. 13, Part 1, the annual summary of provisional vital statistics for the year is presented. Monthly variations for the four major indices, Births, Deaths, Marriages, and Infant Mortality, are shown in Figure 1, [See FIG. 1. in Source Pdf.] which compares the data for 1956 with 1955. It is to be noted that the data are provisional and subject to connection. Previous experience, however, indicates little likelihood of more than very minor changes. Births in 1956 climbed to another recordbreaking high with registered births reaching 4,168,000, on a rate of 24.9 pen 1,000 population. Addition of an estimate for unregistered births raises the total to 4,220,000, or a rate of 25.2. The birth rate has maintained a consistently high level for more than a decade, having achieved a high point of 26.6 in 1947. As in previous years, highest rates centered in the south, lowest in the northeastern areas of the country. Deaths in 1956 totaled 1,565,000, a rate of 9.4 per 1,000 population, slightly higher than the rate of 9.3 in 1955 and the low of 9.2 reached in 1954.

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