scholarly journals Food-induced anaphylaxis in children up to 3-years-old – preliminary study

2021 ◽  
Vol 49 (3) ◽  
pp. 56-64
Author(s):  
Julia Gawryjołek ◽  
Aneta Krogulska
Keyword(s):  
Food Allergy ◽  
Anaphylactic Reaction ◽  
Skin Lesions ◽  
Common Symptom ◽  
Older Children ◽  
Cardiac Symptoms ◽  
The Mean ◽  
Preliminary Study ◽  
Rice Porridge ◽  
Possible Cause

Introduction and objectives: The aim of this study was to determine the frequency of food-induced anaphylaxis, analyze the symptoms, and triggering factors in a group of youngest children. Also, the study aims to estimate the frequency of anaphylaxis episodes in children in the Kuyavian-Pomeranian Voivodeship region.Methods: Retrospective analysis of medical records of 29 children aged 0–3 years that presented symptoms of food-induced anaphylaxis. Medical charts were reviewed using a collection of documents with the clinical data.Results: The frequency of anaphylaxis was determined to be 0.3% of all hospitalized children aged 0–3 years and 1.9% of children suspected of food allergy. The mean age of an anaphylactic reaction was 12±9 months. The most common symptom was mild-moderate urticaria. The respiratory symptoms were significantly more prevalent in toddlers than in infants (p = 0.148). Cardiac symptoms occurred only in the infant group, i.e., in two (11%) infants. As a possible cause of the symptoms, in 18 (62%) cases, parents most often indicated the consumption of milk or milk-rice porridge. Anaphylaxis as the first manifestation of food-allergy was significantly more prevalent in infants than in older children (p = 0.0002).Conclusions: The incidence of anaphylactic reactions rated at 0.3% of all children hospitalized at this age. The most common symptoms of anaphylactic reaction were skin lesions. The primary cause of allergic reactions was cow’s milk after the first exposure at home. Anaphylaxis has different patterns of symptoms depending on the age of the child.

scholarly journals Impact of a Smart-Ring-Based Feedback System on the Quality of Chest Compressions in Adult Cardiac Arrest: A Randomized Preliminary Study

2021 ◽  
Vol 18 (10) ◽  
pp. 5408
Author(s):  
Chiwon Ahn ◽  
Seungjae Lee ◽  
Jongshill Lee ◽  
Jaehoon Oh ◽  
Yeongtak Song ◽  
...  
Keyword(s):  
Primary Outcome ◽  
Feedback System ◽  
Controlled Study ◽  
Feedback Group ◽  
Compression Depth ◽  
System Usability Scale ◽  
The Mean ◽  
Preliminary Study ◽  
The Ideal

This study aimed to assess the effectiveness of a novel chest compression (CC) smart-ring-based feedback system in a manikin simulation. In this randomized, crossover, controlled study, we evaluated the effect of smart-ring CC feedback on cardiopulmonary resuscitation (CPR). The learnability and usability of the tool were evaluated with the System Usability Scale (SUS). Participants were divided into two groups and each performed CCs with and without feedback 2 weeks apart, using different orders. The primary outcome was compression depth; the proportion of accurate-depth (5–6 cm) CCs, CC rate, and the proportion of complete CCs (≤1 cm of residual leaning) were assessed additionally. The feedback group and the non-feedback group showed significant differences in compression depth (52.1 (46.3–54.8) vs. 47.1 (40.5–49.9) mm, p = 0.021). The proportion of accurate-depth CCs was significantly higher in the interventional than in the control condition (88.7 (30.0–99.1) vs. 22.6 (0.0–58.5%), p = 0.033). The mean SUS score was 83.9 ± 8.7 points. The acceptability ranges were ‘acceptable’, and the adjective rating was ‘excellent’. CCs with smart-ring feedback could help achieve the ideal range of depth during CPR. The smart-ring may be a valuable source of CPR feedback.

scholarly journals How Does the Cause of Infantile Hemiparesis Influence Other Conditioning Factors? A Preliminary Study in a Spanish Population

Children ◽  
2021 ◽  
Vol 8 (5) ◽  
pp. 323
Author(s):  
Rocío Palomo-Carrión ◽  
Rita Pilar Romero-Galisteo ◽  
Helena Romay-Barrero ◽  
Inés Martínez-Galán ◽  
Cristina Lirio-Romero ◽  
...  
Keyword(s):  
Ad Hoc ◽  
Cross Sectional Study ◽  
Motor Dysfunction ◽  
Sensory Loss ◽  
Speech Impairments ◽  
Cross Sectional ◽  
Conditioning Factors ◽  
Age Of Diagnosis ◽  
The Mean ◽  
Preliminary Study

Infantile hemiparesis may be associated with significant morbidity and may have a profound impact on a child’s physical and social development. Infantile hemiparesis is associated with motor dysfunction as well as additional neurologic impairments, including sensory loss, mental retardation, epilepsy, and vision, hearing, or speech impairments. The objective of this study was to analyze the association between the cause of infantile hemiparesis and birth (gestational age), age of diagnosis, and associated disorders present in children with infantile hemiparesis aged 0 to 3 years. An observational and cross-sectional study was performed. A simple and anonymous questionnaire was created ad hoc for parents of children diagnosed with infantile hemiparesis aged between 0 and 3 years about the situation regarding the diagnosis of hemiparesis, birth, cause of hemiparesis, and presence of other associated disorders. Perinatal stroke (60.1%) was the most common cause of hemiparesis, and the most typical associated disorder was epilepsy (34.2%), with the second largest percentage in this dimension corresponding to an absence of associated disorders (20.7%). The most frequent birth was “no premature” (74.1%). The mean age of diagnosis of infantile hemiparesis was registered at 8 months (IQR: 0–36). Knowing the possible association between different conditioning factors and the cause of infantile hemiparesis facilitates the prevention of severe sequelae in children and family, implementing an early comprehensive therapeutic approach in children with infantile hemiparesis.

scholarly journals Handling Associated with Drenching Does Not Impact Survival and General Health of Low Birth Weight Piglets

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 404
Author(s):  
Kevin Van Tichelen ◽  
Sara Prims ◽  
Miriam Ayuso ◽  
Céline Van Kerschaver ◽  
Mario Vandaele ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Significant Risk ◽  
Skin Lesions ◽  
Additional Stress ◽  
Bioactive Substances ◽  
Blood Samples ◽  
Panel Test ◽  
Esterified Fatty Acids ◽  
The Mean

The increase in litter sizes in recent years has resulted in more low birth weight (LBW) piglets, accompanied by a higher mortality. A potential intervention to overcome this is drenching bioactive substances. However, if the act of drenching provokes additional stress in LBW piglets, it might counteract the supplement’s effect and be detrimental for the piglet’s survival. To study the effect of the drenching act, piglets from 67 sows were weighed within 4 h after birth. The mean litter birth weight (MLBW) and standard deviation (SD) were calculated. LBW piglets (n = 76) were defined as weighing between (MLBW-1*SD) and (MLBW-2.5*SD). They were randomly allocated to two treatments: “sham” (conducting the act of drenching by inserting an empty 2.5 mL syringe in the mouth during 20 s, once a day, d1 till d7; n = 37) or “no treatment” (no handling; n = 39). On day 1, 3, 9, 24 and 38, piglets were weighed and scored for skin lesions. Blood samples were collected on day 9 and 38 and analyzed to determine glucose, non-esterified fatty acids (NEFA), urea, immunoglobulin G (IgG), insulin-like growth factor 1 (IGF-1) and a standard blood panel test. There was no difference between sham drenched and untreated piglets regarding any of the parameters. In conclusion, this study showed that drenching does not impose a significant risk to LBW piglets and can be applied safely during the first 7 days after birth.

scholarly journals Feasibility of balloon-based endobiliary radiofrequency ablation under cholangioscopy guidance in a swine model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tadahisa Inoue ◽  
Hiromu Kutsumi ◽  
Mayu Ibusuki ◽  
Masashi Yoneda
Keyword(s):  
Radiofrequency Ablation ◽  
Adverse Events ◽  
Swine Model ◽  
Biliary Strictures ◽  
Tissue Samples ◽  
Ablation Area ◽  
Mucosal Changes ◽  
The Mean ◽  
Preliminary Study

AbstractAlthough endobiliary radiofrequency ablation (RFA) has demonstrated considerable potential for the treatment of biliary strictures, conventional catheter RFA has several limitations. This study aimed to evaluate the feasibility of a novel cholangioscopy (CS)-guided balloon-based RFA procedure in vivo using a swine model. CS-guided balloon-RFA was performed under endoscopic retrograde cholangiography guidance at target temperatures of 60 ℃ or 70 ℃, which were maintained for 60 s. We evaluated the technical feasibility, adverse events, and histological effects associated with the procedure. Twelve sites were ablated in seven miniature pigs. The CS-guided balloon-RFA procedure was technically successful in all cases without any hindrance. Mucosal changes could be detected during RFA, and the ablation area was identified on CS. Necropsy was performed in four pigs on the same day as the procedure: the tissue samples showed coagulative necrosis, and the entire internal circumference of the bile duct was uniformly ablated. The mean lengths of the ablation area in the samples ablated at 60 °C and 70 °C were 20.64 and 22.18 mm, respectively, while the mean depths were 3.46 and 5.07 mm, respectively. The other three pigs were reared and euthanized and autopsied 35 days after the procedure. The site to be ablated had replaced the granulation tissue and fibrotic changes. No adverse events were observed in any case. CS-guided balloon-RFA appears to be a promising option for treating biliary strictures. This preliminary study could pave the way for the evaluation of this procedure in future human clinical trials.

Ceftriaxone Associated Biliary Sludge in Children - A Study in Bangabandhu Sheikh Mujib Medical University

2014 ◽  
Vol 37 (3) ◽  
pp. 142-145 ◽  
Author(s):  
M Kabir Alam ◽  
ASM Baslul Karim ◽  
Mosha Hafsa Kabir ◽  
Syed Saimul Huque ◽  
M Samsuzzaman
Keyword(s):  
Child Health ◽  
Side Effect ◽  
Normal Group ◽  
Older Children ◽  
Sludge Formation ◽  
Biliary Sludge ◽  
Paediatric Department ◽  
The Mean ◽  
Medical University ◽  
Higher Doses

Background: Ceftriaxone is known to induce reversible precipitations, called billiary sludge or pseudolithiasis in the gall bladder.Objective: The aim of this study was to investigate the frequency of biliary sludge and factors that contribute to this side effect in children. Methodology: This study was conducted on 50 consecutive children who were admitted at paediatric department of Bangabandhu Sheikh Mujib Medical University (BSMMU) for different illness and who received ceftriaxone in different dosage and duration. Ultraso-nography of hepatobiliary system was done before and at the end of therapy. Children who developed biliary sludge, a third ultrasonography was done after one month. Results: Biliary sludge was found in 4 (08%) of 50 children which resolved within 30 days of cessation of therapy. The mean dose and duration of ceftriaxone in these four children were 92.5±9.6 mg/kg/day and 8.0±2.0 days respectively while it was 78.5±5.2 mg/kg/day and 6.1±1.2 days respectively rest 46 children who did not develop biliary sludge (p<0.05). The mean age of children in sludge formation group was 8.3±2.1 years while it was 5.6±1.6 years in the normal group (p<0.05). Conclusion: Biliary sludge was found in older children who got higher doses of ceftriaxone for a longer period and it was reversible in all the studied children. DOI: http://dx.doi.org/10.3329/bjch.v37i3.18617 Bangladesh J Child Health 2013; Vol.37(3): 142-145

scholarly journals Pseudotumor cerebri in childhood and adolescence: data from a specialized service

2018 ◽  
Vol 76 (11) ◽  
pp. 751-755 ◽  
Author(s):  
Gabriela G. M. Balbi ◽  
Sandro L. Matas ◽  
Claudio A. Len ◽  
Melissa M. Fraga ◽  
Iggor O. Sousa ◽  
...  
Keyword(s):  
Rheumatic Disease ◽  
Disease Onset ◽  
Pseudotumor Cerebri ◽  
Tertiary Hospital ◽  
Outpatient Clinics ◽  
Childhood And Adolescence ◽  
Common Symptom ◽  
Medical Reports ◽  
Specialized Service ◽  
The Mean

ABSTRACT Objective: To report cases of children and adolescents diagnosed with pseudotumor cerebri associated or not with rheumatic disease. Methods: This was a retrospective study based on medical reports of 29 patients, up to 18 years of age and diagnosed with pseudotumor cerebri, followed up in the Pediatric Rheumatology and Neurology outpatient clinics of a tertiary hospital, until December 2016. Results: Among the 29 patients diagnosed with pseudotumor cerebri, 51.7% were girls and the mean age at the disease onset was 12.3 years. In 18 patients (62%) where an etiology was found, four were associated with a rheumatic disease. The most common symptom was headache (69%) and acetazolamide was the most used medication (69%). Two patients developed blindness and 10 are still being followed up. Conclusion: Although rare, pseudotumor cerebri should be considered in children with headaches, especially in patients with rheumatic disease.

scholarly journals Why do some people search for their files much more than others? A preliminary study

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ofer Bergman ◽  
Tamar Israeli ◽  
Yael Benn
Keyword(s):  
Verbal Memory ◽  
Design Methodology ◽  
Demographic Data ◽  
Future Research ◽  
Visuospatial Memory ◽  
Content Type ◽  
Logical Memory ◽  
The Mean ◽  
Preliminary Study ◽  
People Search

PurposePrevious research has repeatedly shown that people only search for files in a small minority of cases when they do not remember the file's location. The current study aimed to examine whether there is a group of hyper-searchers who search significantly more than others. Based on previous neurocognitive studies, this study aims to hypothesize that if such a group exists, they will have superior verbal memory and reduced visuospatial memory.Design/methodology/approachIn total, 65 participants completed a questionnaire estimating their search percentages, as well as reporting demographic data. Verbal memory was measured using the Wechsler logical memory test, and visuospatial memory was assessed using an online card memory game.FindingsHyper-searchers were defined as participants with search percentage of over one standard deviation (SD) above the mean. The average search percentage of the seven participants who met this criterion was 51% (SD = 14%), over five times more than the other participants (M = 10%, SD = 9%). Similar results were obtained by re-analyzing data from four previous papers (N = 1,252). The results further confirmed the hypothesis that hyper-searchers have significantly better verbal memory than other participants, possibly making searching easier and more successful for them. Lastly, the search percentage was positively predicted by verbal memory scores and negatively predicted by visuospatial memory scores. Explanations and future research are discussed.Originality/valueThis preliminary study is the first to introduce the concept of hyper-searchers, demonstrate its existence and study its causes.

scholarly journals Effect of MS on pregnancy and the effect of pregnancy on MS patients in Isfahan

2020 ◽  
Author(s):  
Freshteh Ashtari ◽  
Fatemeh Mokhtari ◽  
Mohammad Soudavi ◽  
Homa Saadat ◽  
Mahboubeh Valiani
Keyword(s):  
Ectopic Pregnancy ◽  
Protective Role ◽  
Common Symptom ◽  
Demographic Information ◽  
Blurred Vision ◽  
Chi Square ◽  
Pregnancy Status ◽  
History Of ◽  
The Mean ◽  
Spss Software

Abstract Background Multiple sclerosis is a chronic disease of the central nervous System.Most women with MS are diagnosed during their reproductive ages.This study evaluated the effect of pregnancy on MS and the effect of MS disease on fertility and pregnancy health. Material & methods: A retrospective descriptive-analytic study was conducted on 110 women suffering from MS with a history of pregnancy(between 2007 and 2017years) in Isfahan, Iran.Samples were selected in a census model.Women completed a researcher-constructed questionnaire by telephone.The questionnaire consisted of three parts: demographic information,MS and its symptoms and its treatment, and the third part was related to the reproductive system and the history of pregnancy associated with MS. Data were analyzed by SPSS software version 16 using Chi-square, ANOVA and t-test.Results The mean age of women with MS was 32.4 years.The most common primary symptom was blurred vision(42.7%).In this population,the average number of pregnancies was 1.61,the number of deliveries was 1.35,the number of abortions was 0.24,the history of ectopic pregnancy was 0.01,the number of alive children was 1.36 and the number of dead children was 0.01.The average time of the last MS attack before the pregnancy was 21.36 months. Fatigue(24.5%) was the most common symptom exacerbated during pregnancy. MS symptoms improved in55.0% of subjects in the second trimester.Discussion MS had no effect on the pregnancy status, such as the number of abortions,ectopic pregnancy, alive and dead children and the duration of pregnancy.The symptoms of the disease are improved during pregnancy.Therefore, pregnancy has a protective role against MS.

scholarly journals Oral and Skin Lesions Among Yemeni Khat Abusers While Chewing and After Quitting：Crosse-Sectional Survey

2021 ◽  
Author(s):  
Rowida A. Albarmaqi ◽  
Yi-Qun Kuang ◽  
Yu-Ye Li ◽  
Noha Saleh Gholais
Keyword(s):  
Standard Deviation ◽  
Dental Health ◽  
Skin Lesions ◽  
Routine Practice ◽  
Cross Sectional ◽  
Khat Chewing ◽  
Skin Symptoms ◽  
Significant Difference ◽  
The Mean ◽  
Symptoms And Signs

Abstract Background: Khat chewing is a routine practice in Yemen. Associations between Khat chewing and various adverse oral-dental health conditions have been recorded, however, adverse skin health evidence is still lacking. Objective: To investigate the difference between oral and skin symptoms and signs while chewing Khat and after quitting chewing among Yemeni khat abusers. Method: A descriptive cross-sectional study was conducted on a sample of 300 Yemeni Khat ex-chewer participants in china. Khat chewing status data, a range of oral and skin symptoms and signs, and other pertinent variables were collected using self-administered questionnaires by WeChat. The mean differences between oral and skin symptoms and signs while chewing Khat and after quitting chewing were investigated using the Paired Samples t-test. Result: Of the 300 Yemeni who participated in the study, 255(85%) were men and 45(15%) were women. The oral symptoms and signs mean while chewing was 0.26, 0.022 (standard deviation [SD], whereas that after quitting chewing Khat was 0.10 (mean), 0.269 (standard deviation [SD], t (12.00), P=0.00. The skin symptoms and signs mean while chewing was 0.13, 0.28 (standard deviation [SD], whereas that after quitting chewing Khat was M=0.06, 0.21(standard deviation [SD], t (9.407), P=0.00. Conclusions: There is a statistically significant difference between the mean oral and skin symptoms and signs while chewing and after quitting, whereas long-term Khat chewing negatively affects oral and skin health.

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