Effect of MS on pregnancy and the effect of pregnancy on MS patients in Isfahan

Abstract Background Multiple sclerosis is a chronic disease of the central nervous System.Most women with MS are diagnosed during their reproductive ages.This study evaluated the effect of pregnancy on MS and the effect of MS disease on fertility and pregnancy health. Material & methods: A retrospective descriptive-analytic study was conducted on 110 women suffering from MS with a history of pregnancy(between 2007 and 2017years) in Isfahan, Iran.Samples were selected in a census model.Women completed a researcher-constructed questionnaire by telephone.The questionnaire consisted of three parts: demographic information,MS and its symptoms and its treatment, and the third part was related to the reproductive system and the history of pregnancy associated with MS. Data were analyzed by SPSS software version 16 using Chi-square, ANOVA and t-test.Results The mean age of women with MS was 32.4 years.The most common primary symptom was blurred vision(42.7%).In this population,the average number of pregnancies was 1.61,the number of deliveries was 1.35,the number of abortions was 0.24,the history of ectopic pregnancy was 0.01,the number of alive children was 1.36 and the number of dead children was 0.01.The average time of the last MS attack before the pregnancy was 21.36 months. Fatigue(24.5%) was the most common symptom exacerbated during pregnancy. MS symptoms improved in55.0% of subjects in the second trimester.Discussion MS had no effect on the pregnancy status, such as the number of abortions,ectopic pregnancy, alive and dead children and the duration of pregnancy.The symptoms of the disease are improved during pregnancy.Therefore, pregnancy has a protective role against MS.

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Predictors of Tuberculosis in HIV Patients in the Clinic Voluntary Counseling and Testing in Medan City

10.21203/rs.2.15469/v1 ◽

2019 ◽

Author(s):

Rahayu Lubis ◽

Jemadi Jemadi ◽

Surya Utama ◽

Rasmaliah Rasmaliah

Keyword(s):

Tertiary Education ◽

Hiv Patients ◽

Chi Square ◽

Voluntary Counseling ◽

Voluntary Counseling And Testing ◽

Counseling And Testing ◽

Chi Square Test ◽

History Of ◽

Low Bmi ◽

Spss Software

Abstract Background: The incidence of tuberculosis in HIV patients (TB-HIV) w as estimated at 126 per 100,000 in the world. The number of HIV infected patients in Indonesia around 190,000 to 400,00 0 and the prevalence of TB-HIV is 5%. Data TB-HIV still increase s and they are un aware of that until a late stage. Understanding the risk factors of people with TB-HIV co-infection is important to know. This study aims to know the predictors of TB-HIV patients in the clinic voluntary counseling and testing (VCT) in Medan city. Methods: This is a case-control study. The case is TB-HIV patients (aged > 20 years) seen at clinic VCT Medan in 2016. Control is HIV patients without TB (aged > 20 years) seen in the same clinic VCT. The number of cases was 120 and the number of control 120. Data were collected from the medical record. Data were analyzed using the chi-square test in SPSS software. Results: The t otal was 240 patients. The majority were in the age group 31-40 years old (52.9%), male (75.8%), married (71.7%), had tertiary education (85.4%), had employment (89.2%) . Significant factors were CD4 < 500 cells/ml (OR 3.92; 95% CI 2.13-7.22), BMI < 18.5 kg/m2 (OR 5.79; 95% CI 3.25-10.21), had history of TB family (OR 7.9; 95% CI 3.67-18.18), adherence ARV (OR 1.35; 95% CI 1.02-1.79). Conclusions: The predictors of incidence TB-HIV co-infection was low CD4, low BMI, and had a family history of TB. Pay the attention for the nutritional status of TB-HIV patients and provide appropriate nutritional intake needs and adherence ARV.

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Cardiovascular Diseases’ Awareness Among Women in Northern Jordan

Global Journal of Health Science ◽

10.5539/gjhs.v11n3p102 ◽

2019 ◽

Vol 11 (3) ◽

pp. 102

Author(s):

Abdulhakeem M Okour ◽

Rami A Saadeh ◽

Neda Redwan ◽

Muhammad Faizal Bin A. Ghani

Keyword(s):

Risk Factors ◽

Cardiovascular Diseases ◽

Cross Sectional Study ◽

Demographic Information ◽

Cross Sectional ◽

Related Risk ◽

History Of ◽

Treatment Plans ◽

The Mean ◽

Health Objectives

BACKGROUND: Women’s awareness of chronic diseases, including cardiovascular diseases, is the cornerstone in promoting women’s health. Objectives: To examine the relationship of awareness levels about cardiovascular diseases and their related risk factors with demographic information of Jordanian women. METHODS: A cross-sectional study of 18 years and older women. Scores of awareness were computed for each individual and were divided into 4 quartiles. Logistic regression analysis was used to examine the association of demographic information of participants with mean scores of quartiles. ANOVA analysis was used to compare the mean scores of quartiles. RESULTS: A total of 514 women completed the questionnaire, with a mean age of 35.46 (±12.53). Current smokers were 6.2%, and 34.6% had a family history of heart disease. The proportion of diabetes, hypertension, hypercholesterolemia, and overweight/obesity were 15.6%, 19.3%, 14.4%, & 21.6% respectively. The mean score for awareness was 12.87 (+ 3.26). Women who had lower income and who were at younger age were more likely to score low in awareness. CONCLUSION: Women illustrated a fair level of awareness of CVD and its related risk factors. Increasing women awareness of CVD through educational programs, targeted toward women at risk, assists in disease prevention and help to improve treatment plans.

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Improvement of Tinnitus following Tympanoplasty and Tympanomastoidectomy Surgeries in Patients with Chronic Otitis Media

Galen Medical Journal ◽

10.31661/gmj.v5i2.647 ◽

2016 ◽

Vol 5 (2) ◽

pp. 63-69

Author(s):

Masoumeh Saeedi ◽

Mohammad Hossein Khosravi

Keyword(s):

Hearing Loss ◽

Otitis Media ◽

Chronic Otitis Media ◽

Cross Sectional Study ◽

Common Symptom ◽

Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Tinnitus Severity ◽

Spss Software

Background: After otorrhea and hearing loss, Tinnitus is the most common symptom in patients with chronic otitis media (COM). The aim of this study was to evaluate the improvement of tinnitus in COM patients after tympanoplasty and tympanomastoidectomy surgeries. Materials and Methods: This cross-sectional study was conducted on COM patients suffering from Tinnitus referred to Baqiyatallah hospital, Tehran, Iran undergoing tympanoplasty or tympanomastoidectomy surgeries between March 2013 and August 2014. Tinnitus Handicap Inventory (THI) and Visual Analogue Scale (VAS) questionnaires were filled before and two months after surgery by each patient, and considered subjects were compared with each other. Audiometry test was taken from each patient before and two months after surgery. Audiometry results as well as Air-Bone gap were measured and evaluated prior and after surgery. Data were analyzed using SPSS software by ANOVA, sample t-test and Chi-square tests. Results: Eventually, 26 male and 24 female patients with a mean age of 38.62±11.88 years were enrolled. Air conduction at all frequencies was 49.99±17.37 before and 36.98±22.06 after surgery (P<0.001). Severity of tinnitus was 62.92±30.54 before and 30.54±20.08 after surgery based on THI (P<0.001). Also, it was 7.46±1.66 before and 3.5±2.06 after surgery based on VAS evaluations (P<0.001). Tinnitus severity reduction was significantly associated with the improvement of hearing loss and decrement of air-Bone gap (P<0.001). Tinnitus symptoms such as loudness, annoyance, impact on life and perception of Tinnitus significantly reduced after surgery. Moreover, Tympanomastoidectomy was more effective on the improvement of Tinnitus in comparison with Tympanoplasty (P=0.019).Conclusion: It seems that, both tympanomastoidectomy and tympanoplasty surgeries are effective on the improvement of tinnitus in patients with COM; however, Tympanomastoidectom surgery was shown to be more effective.[GMJ.2016;5(2):63-69]

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Knowledge about juvenile idiopathic arthritis-associated uveitis: more frequent reminders are associated with higher patient and family uveitis knowledge

Pediatric Rheumatology ◽

10.1186/s12969-021-00639-6 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Ashley M. Cooper ◽

Elaine R. Flanagan ◽

Tova Ronis ◽

Baruch Goldberg ◽

Ashley K. Sherman ◽

...

Keyword(s):

Juvenile Idiopathic Arthritis ◽

Pediatric Rheumatology ◽

Knowledge Score ◽

Demographic Variables ◽

Chi Square ◽

Rheumatology Clinic ◽

History Of ◽

The Mean ◽

Eye Exams

Abstract Background Chronic anterior uveitis is a sight-threatening complication of juvenile idiopathic arthritis (JIA) and a primary contributor to long-term morbidity in people with JIA. Levels of knowledge about uveitis among JIA patients and their parents are unknown. A survey of JIA patients and parents was conducted to assess knowledge about uveitis complications and recommended screening. Methods A survey was developed consisting of six demographic questions, six arthritis/uveitis history questions, and nine uveitis knowledge questions. The survey was administered to JIA patients age 14 and older and parents of patients with JIA at three pediatric rheumatology practices and online through the Patients, Advocates, and Rheumatology Teams Network for Research and Service (PARTNERS) network. ANOVA, chi-square and Fisher’s exact tests were used to look for relationships between survey questions and demographic variables. Results Thirty-three patients and 111 parents completed the survey. Overall, 17.4% reported a history of uveitis, and 89.6% had heard of uveitis. The mean composite knowledge score was 6.46 ± 2.6 out of 9. Patients and parents with a history of uveitis had higher composite knowledge scores than their counterparts without a uveitis history (p = 0.01 and p < 0.01, respectively). Parents whose rheumatologist reminded them about eye exams at every visit had higher knowledge of the risk of blindness (p = 0.04), the risk for uveitis when arthritis is controlled (p = 0.02), the need for ongoing eye exams when off of medications (p = 0.01), and had a higher overall score (p = 0.02) than those who were reminded at some visits or not at all. Conclusions JIA patients and parents report variable levels of knowledge regarding uveitis complications and recommended screening. Frequent discussion between the rheumatology provider and family about uveitis screening is associated with higher uveitis knowledge. Incorporating detailed and frequent education about uveitis into rheumatology clinic appointments may improve early uveitis detection and visual outcomes.

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LO35: Improving the precision of emergency physicians diagnosis of stroke and TIA

CJEM ◽

10.1017/cem.2018.97 ◽

2018 ◽

Vol 20 (S1) ◽

pp. S19-S19

Author(s):

M. A. Cortel ◽

M. Sharma ◽

A. LeBlanc ◽

K. Abdulaziz ◽

J. J. Perry

Keyword(s):

Emergency Physicians ◽

Chi Square ◽

Significant Discrepancy ◽

Backward Elimination ◽

History Of ◽

The Mean ◽

High Index Of Suspicion ◽

Univariate Analyses ◽

Prevention Clinic ◽

Peripheral Vertigo

Introduction: Studies suggest that there is a significant discrepancy between emergency physicians diagnosis of TIA and confirmation by neurologists. The objectives of our study were to identify factors associated with neurologists confirmation of TIA in patients referred from the emergency department. Methods: Data were obtained from a prospective cohort study across more than 8 university-affiliated Canadian hospitals from 2006-2017 of adult patients diagnosed with a TIA or non-disabling stroke in the ED. Patients presenting after 1 week of symptom onset, receiving TPA as part of a stroke code, with a GCS<15 at baseline, and without a neurology assessment within 90 days were excluded. Univariate analyses were performed with t-tests or chi-square tests as indicated. Multivariate analysis with backward elimination was performed to identify unique predictors of TIA confirmation. Results: Of 8,669 patients diagnosed with TIA in the ED, 7,836 (90%) were assessed by neurology. The mean age of patients was 68.2 years and 71.1% presented with their first ever TIA. The rate of confirmation of TIA by neurology was 56%. The most common alternate diagnoses included migraines (26%), peripheral vertigo (10%), syncope (6%), and seizure (4%). The 3 strongest predictors of confirmation of TIA were infarct on imaging (OR 2.31, 2.03-2.63), history of weakness (OR 2.19, 1.95-2.48), and history of language disturbance (OR 2.05, 1.79-2.34). The 3 strongest predictors of an alternate diagnosis were syncope (OR 0.51, 0.39-0.67), history of bilateral weakness (or 0.51, 0.31-0.84), and confusion (OR 0.57, 0.48-0.67). Conclusion: The rate of TIA confirmation by neurology in our study was 56%. Emergency physicians should have a high index of suspicion of TIA in patients with history of weakness and language disturbance, and should resist referring to a stroke prevention clinic, patients with syncope, bilateral findings, or confusion.

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Detection Of Antichlamydial Antibody in Patients With Ectopic Pregnancy and Normal Pregnancy

Kurdistan Journal of Applied Research ◽

10.24017/science.2020.ichms2020.18 ◽

2020 ◽

pp. 160-167

Author(s):

Srwa Jamal Murad

Keyword(s):

Chlamydia Trachomatis ◽

Pregnant Women ◽

Ectopic Pregnancy ◽

Teaching Hospital ◽

Normal Pregnancy ◽

Chlamydia Infection ◽

Pelvic Surgery ◽

P Value ◽

History Of ◽

The Mean

Aim of the current research is to assess the Chlamydia Trachomatis infection role in the development of early pregnancy complication including ectopic pregnancy and miscarriage in Sulaimanyia Maternity Teaching Hospital. It is a comparative study conducted in Gynecology Clinic and Emergency department of Sulaimanyia Maternity Teaching Hospital during the period from 1st of September 2018 to 31st of March 2019. The study groups included of 70 pregnant women; the first group included 35 ectopic pregnant women and the second group included 35 normal pregnant women that both groups had been selected randomly. Pregnant women with history of ectopic pregnancies, women used intrauterine device, in vitro fertilization, assisted reproduction and history of pelvic surgery. Blood sample (2 ml venous blood) collected to test for antibodies level for Chlamydia Trachomatis by Alegria test system for both studied groups and patients with ectopic pregnancy detected by beta human chorionic gonadotropin and ultrasound scanning. The collected data analyzed by SPSS program and for compare between means of two variables independent sample t-test was used while for comparison of categorical variables Chi square test was used with considering ≤ 0.05 P-value as significant level. The results shows that the mean age of normal pregnancy were (28.3±4.6) group compared with mean age ectopic pregnancy (29.5±4.9) group. The mean IgG (6.3±5.1) of patients with ectopic pregnancy was found to be significantly higher than mean IgG (2.8±1.1) for normal pregnant patients (P-value 0.01) and IgM mean (4.5±2.4) of patients with ectopic pregnancy was significantly higher than mean IgM (1.6±1.2) for normal pregnant patients with P-value 0.01. In conclusion, infection of Chlamydia Trachomatis has a significant relationship with the development of ectopic pregnancy therefor screening and treatment of Chlamydia infection may reduce ectopic pregnancy rate with low cost

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Orthodontic Treatment Need in Bangladeshi Young Adults Evaluated Through Dental Aesthetic Index

Bangladesh Journal of Orthodontics and Dentofacial Orthopedics ◽

10.3329/bjodfo.v3i2.24003 ◽

2015 ◽

Vol 3 (2) ◽

pp. 1-8

Author(s):

Kajol Chandra Paul ◽

Md Zakir Hossain

Keyword(s):

Young Adults ◽

Orthodontic Treatment ◽

Age Groups ◽

Cross Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Treatment Need ◽

Chi Square Test ◽

History Of ◽

The Mean

Aim : The objectives of this study were to evaluate the severity of malocclusion and orthodontic treatment need in Bangladeshi young adults by using the Dental Aesthetic Index (DAI).Methods: This cross-sectional study was conducted at Government and private college of Dhaka and Netrokona, Bangladesh. A total of 405 students (from 17 to 25 years old) were selected by convenience sampling. Students wearing orthodontic appliance or reporting a history of orthodontic treatment were excluded from the study. Clinical examinations were conducted using the Dental Aesthetic Index (DAI). The chi-square test (x2) was used to compare malocclusion severity. The analysis of variance (ANOVA) test was used to compare the changes in DAI scores and the mean DAI scores between various age groups. The t test was used to compare the mean DAI scores between sex groups.Results: 405 college students were examined, 305(75.3%) were boys and 100(24.7%) were girls. Most of the students 277(68.4%) had DAI scores ? 25 with no or little malocclusion requiring slight or no orthodontic treatment, 76(18.8%) had DAI score of 26-30 with definite malocclusion requiring elective orthodontic treatment, 34(8.4%) had DAI score of 31-35 with severe type of malocclusion requiring highly desirable orthodontic treatment, 18(4.4%) had DAI score ? 36 with very severe or handicapping malocclusion requiring mandatory orthodontic treatment.Conclusion: The majority of the students in our study (68.4%) required no or little treatment; (12.8%) had definite malocclusion requiring definite orthodontic treatment.Ban J Orthod & Dentofac Orthop, April 2013; Vol-3, No.2

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Relationship between atopic manifestations, family history of atopic disease and cord blood IgE levels in children

Paediatrica Indonesiana ◽

10.14238/pi47.6.2007.278-82 ◽

2007 ◽

Vol 47 (6) ◽

pp. 278

Author(s):

Tisnasari Hafsah ◽

Myrna Soepriadi ◽

Budi Setiabudiawan ◽

Herry Garna

Keyword(s):

Family History ◽

Cord Blood ◽

Atopic Disease ◽

Mean Value ◽

Inclusion Criteria ◽

Chi Square ◽

The Past ◽

History Of ◽

The Mean ◽

The Relationship

Background The incidence of atopic disease tends to increaseover the past few decades and its morbidity interferes with thequality of life and health. Prediction of the disease is importantfor early prevention.Objective To evaluate the relationship between atopicmanifestations, family history (FH) of atopic disease and cordblood IgE (CB-IgE) levels.Methods We conducted an analytic observational study withcohort retrospective design on children with an average age of 3years whose CB-IgE had been measured at delivery inKiaracondong Primary Health Care during October–December2004. Manifestations of atopic disease were recorded using ISAACquestionaire for allergy. Chi-square, Mann-Whitney test, andlogistic regression analysis were used for analysis.Results Cord blood IgE was measured on 124 children after birth.Only 94 children (76%) fulfilled the inclusion criteria. Atopicdisease was found in 17 children (18%), consisting of 8 childrenwith atopic dermatitis, 4 with allergic rhinitis, and 5 suffered fromboth. There were significant differences in the mean value of CB-IgE (Z M-W =4.60; P<0.001) and FH (x 2 =19.059; P<0.001)between atopic and non atopic children. Cut off point of the CB-IgE concentration was 1.4 IU/mL (77.7%). The highest probabilityfor atopic manifestations was found in children who had highCB-IgE and positive FH (P=45%). Relative risk of children withhigh CB-IgE level in positive FH group was 3.636 (95% CI0.943;14.016).Conclusion CB-IgE level and family history of atopic disease arerisk factors for the development of atopic manifestation.

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P01-51-Impulsivity and decision making measured in cocaine addicts in France

European Psychiatry ◽

10.1016/s0924-9338(11)71762-x ◽

2011 ◽

Vol 26 (S2) ◽

pp. 51-51

Author(s):

X. He ◽

V. Bloch ◽

G. Brousse ◽

F. Vorspan ◽

J.-P. Lépine

Keyword(s):

Decision Making ◽

Iowa Gambling Task ◽

Gambling Task ◽

Clinical Factors ◽

Chi Square ◽

Cocaine Use ◽

Cocaine Craving ◽

The Usa ◽

History Of ◽

The Mean

IntroductionImpulsivity and decision making are impaired in cocaine addicts. However, most studies were performed in the USA.ObjectivesTo assess impulsivity and decision making in a sample of French cocaine addicts.MethodsSubjects40 current cocaine addicts and 21 control subjects with no history of drug abuse were compared using the Barratt Impulsiveness Scale (BIS) and Iowa Gambling Task (IGT). Subjects from the cocaine addicted group were evaluated for cocaine craving with the Obessive Compulsive Cocaine Scale (OCCS), and for their pattern of use. Statistical analysis: The mean scores of impulsivity and decision making were compared in the two groups (Mann-Whitney U test). In the group of 40 cocaine addicts, clinical factors that could be associated with high impulsivity and poor decision making scores were tested (Spearman’ s rho, Chi-square and Mann-Whitney U tests).ResultCompared to controls, cocaine addicts had a higher impulsivity score (BIS: 72 ± 11 vs 57 ± 8, U = 138, p < .001) and had more disadvantageous choices on the decision making test (IGT) (advantageous minus disadvantageous choices -4 ± 19 vs 24 ± 35, U = 234, p = .005). There was a significant correlation between high impulsivity scores on the BIS and high cocaine craving as well as heavy cocaine use (more than 4 times a week). No correlation was found between poor decision making and high craving or frequent cocaine use.DiscussionThe discrepancy between impulsivity and poor decision making in cocaine addicts is discussed.

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SARS-CoV-2 Infection in a Spanish Cohort of CKD-5D Patients: Prevalence, Clinical Presentation, Outcomes, and De-Isolation Results

Blood Purification ◽

10.1159/000510557 ◽

2020 ◽

pp. 1-8

Author(s):

José Jesús Broseta ◽

Diana Rodríguez-Espinosa ◽

Elena Cuadrado ◽

Elena Guillén-Olmos ◽

Evelyn Hermida ◽

...

Keyword(s):

Health Resources ◽

Maintenance Hemodialysis ◽

Common Symptom ◽

Time To Death ◽

Reactive Protein ◽

Increased Risk ◽

Discharged Patients ◽

History Of ◽

The Mean ◽

Mean Time

Introduction: COVID-19 is a highly contagious disease that has easily spread worldwide. Outpatient maintenance hemodialysis seems to entail an increased risk of contagion, and previous reports inform of increased mortality among this population. Methods: We retrospectively analyzed clinical and laboratory parameters, outcomes, and management once discharged of CKD-5D patients infected with SARS-CoV-2 from our health area. Results: Out of the 429 CKD-5D population, 36 were diagnosed with SARS-CoV-2 infection (8%): 34 on in-center hemodialysis and 2 on peritoneal dialysis. Five were asymptomatic. The most common symptom was fever (70%), followed by dyspnea and cough. History of cardiovascular disease and elevation of LDH and C-reactive protein during admission were associated with higher mortality. Thirteen patients died (36%), 8 patients were admitted to an ICU, and survival was low (38%) among the latter. The mean time to death was 12 days. Most discharged patients got negative rRT-PCR in nasopharyngeal swabs within 26 days of diagnosis. However, there is a portion of cured patients that continue to have positive results even more than 2 months after the initial presentation. Conclusions: Patients on dialysis have an increased mortality risk if infected with SARS-CoV-2. Preventive measures have proven useful. Thus, proper ones, such as universal screening of the population and isolation when required, need to be generalized. Better de-isolation criteria are necessary to ensure an appropriate use of public health resources.

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