scholarly journals Bronchopulmonary Dysplasia: a Modern View on Course and Outcomes

2016 ◽  
Vol 13 (4) ◽  
pp. 367-372 ◽  
Author(s):  
K. A. Kazakova

The studying of various courses and outcomes of bronchopulmonary dysplasia is an important direction of modern pediatric research. Researchers of different profiles have an interest in the issue not only due to the recent publication of results obtained after 50-yearlong observations which occurred since the disease has been described for the first time, but also due to the successes of functional diagnostics and the improvements made in visualizing structural lesions in the lungs. The review describes the modern concepts concerning the course of bronchopulmonary dysplasia, as well as the factors affecting the disease outcomes.

2021 ◽  
Vol 11 ◽  
Author(s):  
Saboor Ahmad ◽  
Shahmshad Ahmed Khan ◽  
Khalid Ali Khan ◽  
Jianke Li

Hypopharyngeal glands (HGs) are the most important organ of hymenopterans which play critical roles for the insect physiology. In honey bees, HGs are paired structures located bilaterally in the head, in front of the brain between compound eyes. Each gland is composed of thousands of secretory units connecting to secretory duct in worker bees. To better understand the recent progress made in understanding the structure and function of these glands, we here review the ontogeny of HGs, and the factors affecting the morphology, physiology, and molecular basis of the functionality of the glands. We also review the morphogenesis of HGs in the pupal and adult stages, and the secretory role of the glands across the ages for the first time. Furthermore, recent transcriptome, proteome, and phosphoproteome analyses have elucidated the potential mechanisms driving the HGs development and functionality. This adds a comprehensive novel knowledge of the development and physiology of HGs in honey bees over time, which may be helpful for future research investigations.


2020 ◽  
Vol 54 (2) ◽  
pp. 497-513 ◽  
Author(s):  
L. N. Beldiman ◽  
I. N. Urbanavichene ◽  
V. E. Fedosov ◽  
E. Yu. Kuzmina

We studied in detail a moss-lichen component of Shokalsky Island vegetation for the first time and identified 79 species of mosses and 54 species and 2 subspecies of lichens and lichenicolous fungi. All species of mosses and 23 species and 2 subspecies of lichens and lichenicolous fungi are recorded for the first time for the island. The study is based on collections made in South West part of the island, in arctic tundra. We also explored the participation of the mosses and lichens in the main types of plant communities and the species distribution in 10 ecotopes. The paper describes the noteworthy findings (Abrothallus parmeliarum, Aongstroemia longipes, Arthonia peltigerea, Caloplaca caesiorufella, Catillaria stereocaulorum, Ceratodon heterophyllus, Lecanora leptacinella, Sphagnum concinnum, S. olafii) and features of bryo- and lichenoflora of Shokalsky Island.


1998 ◽  
Vol 18 (1) ◽  
pp. 121-137 ◽  
Author(s):  
Pamela I. Erickson

In 1995, the Latina adolescent birth rate surpassed that of African Americans for the first time. This article investigates cultural and social factors affecting the initiation of sexual intercourse among Latina adolescent mothers in Los Angeles. The data are from life history interviews with forty young mothers and their partners conducted in 1994 to 1997. Results suggest that sexual intercourse is initiated within the context of the couple's developing relationship, and that the course of relationships is highly scripted. Men pressure for sex and women resist. Women should be ignorant about sex, but control access to intercourse. Sex is never discussed. Thus, it is unexpected, and contraception other than withdrawal is not used. This script places young Latinas at enormous risk for pregnancy and STDs.


Author(s):  
Matteo Marchioro ◽  
Massimo Faccoli

AbstractThe Walnut Twig Beetle (WTB), Pityophthorus juglandis Blackman, is a small bark beetle native to Mexico and Southwestern USA recorded for the first time in Europe (NE Italy) in 2013. WTB attacks walnut (Juglans spp.) and wingnut trees (Pterocarya spp.) and is the vector of Geosmithia morbida Kolarík et al., a pathogen causing the thousand cankers disease (TCD). WTB and TCD represent a serious threat for walnut orchards in Europe. Spatiotemporal data of the WTB-TCD infestations recorded from an 8-year-long (2013–2020) monitoring conducted in 106 walnut orchards of NE Italy were used to develop a model in order to analyze: (i) the effective dispersal capacity of WTB, (ii) the factors affecting dispersal and (iii) the colonization risk of healthy walnut orchards. We registered a mean annual dispersal of 9.4 km, with peaks of about 40 km. Pest dispersal is affected by distance of suitable hosts from the nearest infested site, number of walnut orchards in the surroundings (both infested and healthy), orchard size and walnut species in the orchard. Using the model, it was also possible to calculate the colonization risk of a specific walnut orchard according to its characteristics showing, for instance, that a medium-size (5,000 trees) black walnut orchard located at 25 km from the nearest infested orchard has an infestation risk of about 50% of probability.


2019 ◽  
Vol 946 ◽  
pp. 380-385
Author(s):  
Boris A. Chaplygin ◽  
Viacheslav V. Shirokov ◽  
Tat'yana A. Lisovskaya ◽  
Roman A. Lisovskiy

The strength of abrasive wheels is one of the key factors affecting the performance of abrasive machining. The paper discusses ways to improve the strength of abrasive wheels. The stress-state mathematical model presented herein is a generalization of the existing models. It is used herein to find for the first time that there are numerous optimal combinations of the elastic modulus and reinforcing material density, which result in the same minimum value of the objective function. It is found out that increasing the radius of the reinforcing component while also optimizing the mechanical properties of its material may increase the permissible breaking speed of the wheel several times. We herein present a regression equation and a nomogram for finding the optimal combination of control factors. Conventional methods for testing the mechanical properties of materials, which have been proven reliable for testing metals and alloys, are not as reliable for testing abrasive materials, as the test results they generate are not sufficiently stable or accurate. We therefore propose an alternative method that does not require any special equipment or special studies.


2006 ◽  
Vol 27 (5) ◽  
pp. 1859-1867 ◽  
Author(s):  
Ritu Kulshreshtha ◽  
Manuela Ferracin ◽  
Sylwia E. Wojcik ◽  
Ramiro Garzon ◽  
Hansjuerg Alder ◽  
...  

ABSTRACT Recent research has identified critical roles for microRNAs in a large number of cellular processes, including tumorigenic transformation. While significant progress has been made towards understanding the mechanisms of gene regulation by microRNAs, much less is known about factors affecting the expression of these noncoding transcripts. Here, we demonstrate for the first time a functional link between hypoxia, a well-documented tumor microenvironment factor, and microRNA expression. Microarray-based expression profiles revealed that a specific spectrum of microRNAs (including miR-23, -24, -26, -27, -103, -107, -181, -210, and -213) is induced in response to low oxygen, at least some via a hypoxia-inducible-factor-dependent mechanism. Select members of this group (miR-26, -107, and -210) decrease proapoptotic signaling in a hypoxic environment, suggesting an impact of these transcripts on tumor formation. Interestingly, the vast majority of hypoxia-induced microRNAs are also overexpressed in a variety of human tumors.


2012 ◽  
Vol 6 ◽  
pp. CMC.S8976 ◽  
Author(s):  
Yousif Ahmad ◽  
Gregory Y.H. Lip

Atrial fibrillation is the commonest arrhythmia worldwide and is a growing problem. AF is responsible for 25% of all strokes, and these patients suffer greater mortality and disability. Warfarin has traditionally been the only successful therapy for stroke prevention, but its limitations have resulted in underutilisation. Major progress has been made in AF research, leading to improved management strategies. Better risk stratification permits identification of truly low-risk patients who do not require anticoagulation and we are able to simplify ourevaluation of a patient's bleeding risk. The advent of novel anticoagulants means warfarin is no longer the only choice for stroke prophylaxis. These drugs circumvent many of warfarin's inconveniences, but only long-term study and use will conclusively demonstrate how they compare to warfarin. The landscape of stroke prevention in AF has changed with effective alternatives to warfarin available for the first time in 60 years—but each new option brings new considerations.


2016 ◽  
Vol 11 (3) ◽  
pp. 119 ◽  
Author(s):  
Abdullah AL-Mutairi ◽  
Muna Saeid

The attempt is made in this study to identify students’ motives and reasons behind enrolling in a MBA program offered by universities operating in Kuwait. It also explores criterion used to select the program. To achieve these objectives, data were collected through a well-designed and structured questionnaire and pre-testing was carried out to examine the efficiency of the instrument. The study showed that the main reasons behind selecting the MBA program by students are to satisfy their personal concerns and improve their knowledge and skills. Moreover, the students used program alumni and campus visit as main sources of information followed by friends’ suggestions and university websites. When evaluating the MBA programs, the students cited overseas accreditation as the most used criteria followed by faculty reputation, institution reputation and admission requirements.


1988 ◽  
Vol 135 ◽  
Author(s):  
M. O. Manasreh ◽  
D. O. Pederson ◽  
T. S. Aurora

AbstractMeasurements of the ultrasonic attenuation and velocity have been made in solid electrolytes with fluorite structure, PbF2, BaF2, and CdF2, from room temperature to temperature at or above the diffuse solid electrolyte transition temperature, Tc. The ultrasonic attenuation peaks observed in this class of materials are associated only with the ionic conductivity saturation rather than in combination with crystallographic phase transition found in many other solid electrolytes. The relaxation rates and Arrhenius activation energies for anion motion above the transition temperature were obtained from the temperature dependence of the ultrasonic attenuation and the theory of local site fluctuations. The ultrasonic attenuation peaks observed for the first time in CdF2was used to define the diffuse transition temperature in this material. An Anomalous peak is also observed in the linear thermal expansion coefficient of PbF2.


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