scholarly journals Tuberculosis in Northeastern Brasil (2001-2016): trend, clinical profile, and prevalence of risk factors and associated comorbidities

2020 ◽  
Vol 66 (9) ◽  
pp. 1196-1202 ◽  
Author(s):  
Alyne Barbosa Brito ◽  
Williany Barbosa de Magalhães ◽  
João Paulo Silva de Paiva ◽  
Thiago Cavalcanti Leal ◽  
Leonardo Feitosa da Silva ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Temporal Trend ◽  
Public Health Problem ◽  
Descriptive Statistics ◽  
Clinical Profile ◽  
Smear Microscopy ◽  
Cure Rate ◽  
Male Population ◽  
Positive Smear

SUMMARY OBJECTIVE: To describe the temporal trend, clinical profile, and the prevalence of risk factors and associated comorbidities in new cases of tuberculosis in the Northeast (2001-2016). METHODS: A prevalence study involving all tuberculosis cases registered in Northeast Brasil, 2001-2016. Data were obtained from the National System of Notification of Disorders. For statistical analysis, the inflection point regression model and descriptive statistics were used. RESULTS: 331,245 cases of tuberculosis were reported. The overall incidence rate decreased from 44.84/100,000 inhabitants (2001) to 30.92/100,000 inhabitants (2016), with a decreasing trend (AAPC: −2.3; p<0.001). The profile was characterized by men (73.53%), age 20-59 years (73.56%), pulmonary tuberculosis (86.37%), positive smear microscopy (54.78%). The main risk factors and comorbidities were: AIDS (4.64%), HIV (12.10%), Diabetes mellitus (5.46%), alcohol (11.63%), institutionalized, (4.31%) and deprived of liberty (2.30%). The cure rate was 70.66% and the abandonment rate was 9.11%. CONCLUSIONS: Even with a reduced incidence, tuberculosis represents a real public health problem in the Northeast region. The profile was characterized by a male population, in economically-active age, lung smear-positive pulmonary presentation, and the risk factors and comorbidities of Aids, TB/HIV co-infection, diabetes mellitus, alcohol consumption, institutionalized and deprived of freedom reflect the complexity of the challenges in facing the disease.

scholarly journals Diabetes mellitus and other cardiovascular risk factors in lower-extremity peripheral artery disease versus coronary artery disease: an analysis of 1,121,359 cases from the nationwide databases

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Mitsuyoshi Takahara ◽  
◽  
Osamu Iida ◽  
Shun Kohsaka ◽  
Yoshimitsu Soga ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Lower Extremity ◽  
Cardiovascular Risk Factors ◽  
Clinical Profile ◽  
Peripheral Artery ◽  
Artery Disease

Abstract Background Lower-extremity peripheral artery disease (LE-PAD) and coronary artery disease (CAD) are both pathologically rooted in atherosclerosis, and their shared clinical features regarding the exposure to cardiovascular risk factors have been emphasized. However, comparative data of the two cardiovascular diseases (CVDs) were so far lacking. The purpose of this study was to directly compare the clinical profile between cases undergoing endovascular therapy (EVT) for LE-PAD and those undergoing percutaneous coronary intervention (PCI). Methods Data were extracted from the nationwide procedural databases of EVT and PCI in Japan (J-EVT and J-PCI) between 2012 and 2017. A total of 1,121,359 cases (103,887 EVT cases for critical limb ischemia [CLI] or intermittent claudication and 1,017,472 PCI cases for acute coronary syndrome [ACS] or stable angina) were analyzed. Heterogeneity in clinical profile between CVDs was evaluated using the C statistic of the logistic regression model for which dependent variable was one CVD versus another, and explanatory variables were clinical profile. When two CVDs were completely discriminated from each other by the developed model, the C statistic (discrimination ability) of the model would be equal to 1, indicating that the two CVDs were completely different in clinical profile. On the other hand, when two CVDs were identical in clinical profile, the developed model would not discriminate them at all, with the C statistic equal to 0.5. Results Mean age was 73.5 ± 9.3 years in LE-PAD patients versus 70.0 ± 11.2 years in CAD patients (P < 0.001). The prevalence of diabetes mellitus and end-stage renal disease was 1.96- and 6.39-times higher in LE-PAD patients than in CAD patients (both P < 0.001). The higher prevalence was observed irrespective of age group. The exposure to other cardiovascular risk factors and the likelihood of cardiovascular risk clustering also varied between the diseases. The between-disease heterogeneity in patient profile was particularly evident between CLI and ACS, with the C statistic equal to 0.833 (95% CI 0.831–0.836). Conclusions The current study, an analysis based on nationwide procedural databases, confirmed that patient profiles were not identical but rather considerably different between clinically significant LE-PAD and CAD warranting revascularization.

scholarly journals Risk Factors for Diabetes Type 2 Development. Comparison of 6 Major Risk Factors Prevalence Between Newly Diagnosed Diabetes Patients from Bihor County and the Population with Normal Glucose Tolerance from Predatorr Study

2018 ◽  
Vol 15 (3) ◽  
pp. 33-38
Author(s):  
Vesa Cosmin Mihai ◽  
Popa Amorin Remus
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Healthy Lifestyle ◽  
Public Health Problem ◽  
Diabetes Type 2 ◽  
Normal Glucose Tolerance ◽  
Newly Diagnosed ◽  
Modifiable Factors

AbstractDiabetes mellitus represents a public health problem because of its growing prevalence and the enormous costs for its treatment and complications. There are numerous risk factors for diabetes mellitus development but the most important ones are the modifiable factors. In Bihor County the prevalence of obesity and sedentary behaviour in the population of newly diagnosed patients are increased compared to their prevalence in the population without diabetes. Promotion of healthy eating habits and increased physical effort are the most important measures to prevent diabetes mellitus type 2, which accounts for 90-95% of total diabetes cases. Public health programs that bring together physicians, nutritionists, teachers and target groups (children, young people, obese and overweight people)must be initiated in general population from an early age and maintained in order to promote the adherence to a healthy lifestyle.

scholarly journals Prevalence and Subtype Distribution of Blastocystis Infection in Patients with Diabetes Mellitus in Thailand

2020 ◽  
Vol 17 (23) ◽  
pp. 8877
Author(s):  
Noppon Popruk ◽  
Satakamol Prasongwattana ◽  
Aongart Mahittikorn ◽  
Attakorn Palasuwan ◽  
Supaluk Popruk ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Public Health Problem ◽  
Binary Logistic Regression ◽  
Small Subunit ◽  
Rrna Gene ◽  
Global Public Health ◽  
Blastocystis Infection ◽  
Nested Polymerase Chain Reaction ◽  
Potential Risk Factors

Diabetes mellitus (DM) is a major global public health problem with an increasing prevalence. DM increases the risk of infections caused by bacteria, fungi, viruses, and parasites. We examined the prevalence, subtypes, and risk factors of Blastocystis infection in patients with and without DM in central Thailand. Stool samples and questionnaires were obtained from 130 people in the DM group and 100 people in the non-DM group. Blastocystis infection was identified via a nested polymerase chain reaction and subtyped via sequencing of the partial small-subunit ribosomal RNA (SSU rRNA) gene. Analysis of potential risk factors was conducted via binary logistic regression. The overall prevalence of Blastocystis infection was 10.8%, including rates of 9% and 12.3% in the non-DM and DM groups, respectively. The most prevalent subtype was ST3, followed by ST1, and ST4. Factors that potentially increased the risk of Blastocystis infection include patients being >65 years old, the presence of DM, a DM duration of ≥10 years, a low level of education, and animal ownership. In conclusion, this is the first study of Blastocystis infection in DM, and a high prevalence was found among this population. Therefore, health education promoting sanitation and hygiene is necessary to reduce and prevent infection in the community.

scholarly journals Influence of cardiovascular risk factors on the occurrence of foot risk, prior to the complementary study with infrared thermography

2019 ◽  
Vol 18 (3) ◽  
pp. 35-57
Author(s):  
Álvaro Astasio Picado ◽  
Elena Escamilla Martínez ◽  
Beatriz Gómez Martín
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
At Risk ◽  
Infrared Thermography ◽  
Diabetic Foot ◽  
Public Health Problem ◽  
Control Group ◽  
Cross Sectional ◽  
Factores De Riesgo ◽  
And Control

Introducción: La Diabetes Mellitus es un problema de salud pública. El Pie diabético es una degeneración de la estructura vascular de los pies, cuyos pacientes presentan problemas neurológicos, necesarios de identificar en el menor tiempo posible. Objetivo: El objetivo del estudio es analizar la influencia de los factores de riesgo en la aparición del pie de riesgo, como datos complementarios al estudio mediante termografía infrarroja. Método: Se plantea un estudio descriptivo, transversal y observacional sobre una muestra de 479 sujetos encuadrados en dos grupos, grupo casos (personas con diabetes) y grupo control (personas sin diabetes). El grupo casos compuesto de un total de 277 personas, con una edad media de 63.41 años, [138 hombres (49.8%) y 139 mujeres (50.2%)]. De igual modo para el grupo control, el número consistió en 202 usuarios, con una edad media de 61.92 años, [ 99 hombres (49%) y 103 mujeres (51%)]. La toma de imágenes se ha llevado a cabo con la cámara FLIR E60bx® (FLIR® Company, Boston, USA). El análisis estadístico de los datos obtenidos se ha realizado utilizando el paquete estadístico IBM SPSS Statistics 22.Conclusión: Se puede concluir afirmando que el estudio de los diferentes factores de riesgo es clave en el diagnóstico del pie de riesgo. Se puede establecer con rotundidad que la edad es un condicionante evidente, ya que las edades avanzadas se corresponden con un IMC y perímetro abdominal mayor. Unido al análisis mediante termografía infrarroja en la evaluación del pie de riesgo es útil para el diagnóstico y prevención de zonas comprometidas del pie, evitando así el desencadenante evidente en los daños propios de un pie diabético. Introduction: Diabetes mellitus is a public health problem. The diabetic foot is a degeneration of the vascular structure of the feet, whose patients present neurological problems that need to be identified in the shortest possible time.Objective: The study's objective was to analyse the influence of risk factors in the appearance of the foot at risk as complementary data to the infrared thermography study.Method: A descriptive, cross-sectional, and observational study was proposed for a sample of 479 subjects corresponding to two groups – cases (subjects with diabetes) and control (subjects without diabetes). The cases group comprised 277 subjects, mean age 63.41 years, 138 men (49.8%) and 139 women (50.2%). The control group comprised 202 subjects, mean age 61.92 years, 99 men (49%) and 103 women (51%). Images were taken with an FLIR E60bx® camera (FLIR® Company, Boston, USA). The statistical analysis of the data was carried out using the IBM SPSS Statistics 22 statistical package.Conclusion: It can be concluded that the study of the different risk factors is key to the diagnosis of the foot at risk. It was solidly established that age evidently conditions the risk, since advanced ages corresponded to greater BMI and waist circumference. This type of study, together with the analysis by infrared thermography, is useful for the diagnosis and prevention of compromised areas of the foot, thus avoiding the obvious triggering of the damage typical of a diabetic foot.

scholarly journals CLINICAL SIGNIFICANCE AND RISK FACTORS OF DYSTOCIA

2020 ◽  
Vol 20 (2) ◽  
pp. 37-41
Author(s):  
O.V. Grishchenko ◽  
S. S. Mamedova
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Genital Tract ◽  
Odds Ratio ◽  
Gestational Hypertension ◽  
Clinical Importance ◽  
Descriptive Statistics ◽  
Reproductive Age ◽  
Pregnancy And Childbirth ◽  
Therapeutic Measures

Reducing adverse events in labour is one of key tasks of obstetrics at present. Abnormalities in labour, and in particular, dystocia, require further in-depth investigation and coordinated interprofessional effort. The purpose of this study was to determine the risk factors for dystocia in a full-term monocyesis with foetal presentation. We carried out a clinical and statistical analysis of pregnancy and childbirth histories of 550 women at the Kharkiv Municipal Perinatal Centre for 2018-2019 depending on the presence of dystocia by applying descriptive statistics and the odds ratio (OR) methods. Results. The most important factors for dystorcia with OR > 5.0 include diabetes mellitus (OR - 10.023; 95% CI 3.083-32.578), burdened gynecological history (OR - 7.385; 95% CI 2.671 - 20.423), foetus-pelvic imbalances (OR - 6.399; 95% CI 1.506 - 27.180) first birth (OR - 5.878; 95% CI 3.139 - 11.009) and the presence of infectious diseases of the genital tract (OR - 5.071; 95% CI 1.847 - 13.925). The value for preeclampsia was slightly lower (OR - 4.467; 95% CI 1.585 - 12.586). All other indicators had an OR < 3.0, including gestational hypertension (OR - 2.882; 95% CI 1.388 - 6.071), obesity (OR - 2.360; 95% CI 1.118 - 4.98) large foetus (OR - 2.242; 95% CI 1.069 - 4,704) late reproductive age (OR - 2.075; 95% CI 1.144 - 3.765) and the presence of cardiovascular disease (OR - 2.040; 95% CI 1.009 - 4.124). A comprehensive assessment of risk factors is of great clinical importance for predicting dystocia and making decisions about the need for preventive and therapeutic measures.

scholarly journals Prevalence, Risk Factors, and Fetomaternal Outcomes of Gestational Diabetes Mellitus in Kuwait: A Cross-Sectional Study

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Zainab Groof ◽  
Ghadeer Garashi ◽  
Hamid Husain ◽  
Shaikhah Owayed ◽  
Shaima AlBader ◽  
...  
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Sectional Study ◽  
Cross Sectional

Objective. Gestational diabetes mellitus (GDM) is a growing global public health problem that can have short- and long-term health consequences for the mother and the child. Despite its criticalness, many countries still do not have the epidemiological data which could guide them in responding to the problem. Due to the lack of knowledge on GDM and the fact that diabetes and obesity are high in Kuwait, this study sought to estimate the prevalence of GDM and determine its risk factors and outcomes. Methods. This cross-sectional study enrolled 947 mothers living in Kuwait, who had given birth within the previous four years. Participants were recruited from primary health care clinics and public hospitals. GDM status was self-reported by the mother. Associations between exposures and outcomes were evaluated using logistic regression, and adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were estimated. Results. Of the 868 mothers with no prior history of diabetes mellitus, 109 (12.6%, 95% CI: 10.4, 14.8) reported having been given a GDM diagnosis during their last pregnancy. The prevalence of GDM increased with maternal age and prepregnancy body mass index. GDM was positively associated with caesarean section delivery (aOR=1.76, 95% CI: 1.17, 2.66) and fetal macrosomia (aOR=2.36, 95% CI: 1.14, 4.89). Conclusion. GDM is prevalent in Kuwait and is associated with poor maternal, fetal, and neonatal outcomes. To date, GDM has received little attention, and there is a need for more research to identify and respond to individual and public health implications of GDM in Kuwait.

scholarly journals Prevalence and risk factors of pulmonary tuberculosis among people living with diabetes mellitus at the National Referral Hospital, Thimphu, Bhutan

2021 ◽  
Vol 7 (1) ◽  
pp. 24-28
Author(s):  
Wangchuk Wangchuk ◽  
Pem Chuki ◽  
Kinley Dorji ◽  
Tshering Dhendup ◽  
Nidup Dorji
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Pulmonary Tuberculosis ◽  
Median Duration ◽  
Referral Hospital ◽  
Sputum Smear ◽  
Smear Microscopy ◽  
Positive Symptoms ◽  
Good Glycemic Control ◽  
National Referral Hospital

Introduction: Diabetes mellitus (DM) is increasing the risk of pulmonary tuberculosis (PTB) with concern over the convergence of these two diseases. Although screening for PTB among people with DM has been recommended by WHO, it has not been implemented in Bhutan yet. Objective: The aim of this study was to determine the prevalence and risk factors of PTB among people living with DM at the National Referral Hospital (NRH), Thimphu, Bhutan. Methods: This was a cross-sectional study conducted from 1st June – 9th October 2018. All 343 consenting DM patients were screened for PTB using the WHO recommended questionnaire and those with TB positive symptoms were tested for active PTB using sputum smear microscopy and Gene-Xpert. A descriptive statistical analysis was performed using SPSS 21. Results: The prevalence of PTB among people living with DM was 0.87% (95% CI: 0.20-2.50).The mean age was 54.95 (± 13.2 years) and all were DM type II. The median duration of diabetes was 4 years (range of 0.1-40 years), an average level of HbA1c 7.47 (± 2.6), and median duration on DM medication was 4 years (range of 0.1-40 years) with the majority (88.9%) on oral hypoglycemic drugs. Good glycemic control (HbA1c< 7) was achieved by 39.4% of individuals. PTB risk factors included PTB positive symptoms (7.0%), prior PTB history (5.5%) and recent contact with PTB patient (5.0%). Additional known PTB risk factors were smoking (7.6%), alcohol use (4.1%) and low body mass index (1.5%). Conclusions: Although the prevalence PTB was low, health education, proper case management and risk based screening for PTB among DM is recommended.

scholarly journals Diabetes Mellitus Gestacional com ênfase nas Gestantes de Alto Risco / Gestational Diabetes Mellitus with an emphasis on High-Risk Pregnant Women

2021 ◽  
Vol 15 (58) ◽  
pp. 278-291
Author(s):  
Ana Luiza Almeida da Silva ◽  
Ana Paula Silveira Santos ◽  
Simei Gleide Silva Matos ◽  
Matheus Santos Marques
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
High Risk ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Public Health Problem ◽  
High Risk Pregnancy ◽  
Mortality Factors ◽  
Risk Pregnancy

Resumo: Considerando o Diabetes Mellitus um problema de saúde pública e sendo um dos principais fatores de morbimortalidade no Brasil, torna-se relevante destacar o aumento de casos ocorridos do DMG em gestantes de alto risco. Esta pesquisa teve por objetivo: investigar o perfil clínico do diabetes mellitus gestacional (DMG) e como o mesmo pode levar a uma gravidez de alto risco, sua associação aos fatores de riscos e suas principais complicações. Quanto à metodologia é exclusivamente de caráter bibliográfico. Foi feita uma pesquisa de revisão bibliográfica, a qual utilizou fontes de internet, onde foram aplicados critérios de inclusão e exclusão, chegando a um total de 12 artigos selecionados. A partir desses artigos, a pesquisa verificou que os fatores de riscos associados ao DMG e suas complicações, fazem correlação com a gravidez de alto risco. Assim, se faz necessário o rastreamento e monitoramento, a prevenção, o diagnóstico e tratamento do DMG tanto para a mãe quanto para o feto. Logo é fundamental a atuação do farmacêutico na equipe multidisciplinar, pois contribui desde a gestão, aquisição até a dispensação eficiente dos medicamentos auxiliando de forma a reduzir os riscos, promovendo atenção, cuidado e uma saúde de qualidade às gestantes. Palavras Chave: Diabetes Mellitus. Diabetes Mellitus Gestacional. Gravidez de Alto Risco. Abstract: Considering Diabetes Mellitus a public health problem and one of the main morbidity and mortality factors in Brazil, it is relevant to highlight the increase in cases of GDM in high-risk pregnant women. This research aimed to: investigate the clinical profile of gestacional diabetes mellitus (GDM) and how it can lead to a high-risk pregnancy, its association with risk factors and its main complications. As for the methodology, it is exclusively bibliographic in nature. A bibliographic review research was carried out, using internet  sources,  where inclusion   and exclusion  criteria   were applied, reaching a total of  12 selected articles. From these articles, the research found that the risk factors associated with GDM and its complications are correlated with high-risk pregnancy. Thus, it is necessary the tracking and monitoring, prevention, diagnosis and treatment of GDM for both mother and fetus. Therefore, the role of the pharmacist in the multidisciplinary team is essential, as he contributes from the management, acquisition to the efficient dispensing of medicines, helping to reduce risks, promoting attention, care and quality health for pregnant women. Keywords: Diabetes Mellitus. Gestational Diabetes Mellitus. High-risk Pregnancy.

scholarly journals Influence of Race in the Association of Diabetes and Heart Failure

2018 ◽  
Vol 12 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Hou Tee Lu ◽  
Rusli Bin Nordin ◽  
Aizai Azan Bin Abdul Rahim ◽  
◽  
◽  
...  
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Heart Failure ◽  
Racial Differences ◽  
Race And Ethnicity ◽  
Public Health Problem ◽  
Racial Groups ◽  
Global Public Health ◽  
Readmission Rates

Heart failure is a global public health problem with high mortality and readmission rates. Race and ethnicity are useful concepts when attempting to understand differential health risks and health disparities. With cardiovascular diseases accounting for most deaths globally, eliminating racial disparities in cardiac care has become a new challenge in cardiology. Significant racial differences exist in patients with heart failure. African American patients in the US have a significantly higher incidence of heart failure, lower ejection fraction and are younger at presentation compared to White, Hispanic and Chinese American patients. These findings are explained by a higher burden of risk factors such as diabetes mellitus, hypertension, obesity and lower household incomes among African Americans. The authors believe that these findings are applicable to other racial groups across the globe. The prevalence of predisposing risk factors probably has a stronger influence on the incidence of heart failure than the racial factor alone. The interaction between race and diabetes mellitus has important public health implications for the management and prevention of heart failure.

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