scholarly journals Physical Exercises By Giving Glutathione for Changes of Leukocytes, Neutrophils, and Lymphocytes Amounts

2020 ◽  
Vol 9 (2) ◽  
pp. 137-141
Author(s):  
Tuty Yanuarti ◽  
Sugiharto Sugiharto
Keyword(s):  
Physical Exercise ◽  
The Body ◽  
Control Group ◽  
Profile Measurement ◽  
Control Group Design ◽  
Group Design ◽  
The Third ◽  
Physical Exercises ◽  
Randomized Control ◽  
Age Range

Physical exercise changes the antibody endurance of each person. This study aims to determine in depth changes in the number of leukocytes, neutrophils, and lymphocytes using physical exercise after being given glutathione. The method used experimentally using a posttest randomized control group design. The study was conducted in three groups where each group consisting of men and women who are in the age range of 20-30 years. Each group consisted of 10 people (n), K1 was given a placebo, K2 was given glutathione 54 mg / kg BW, K3 given 108 mg / kg BW. All treatments are given intraperitoneally twice a day until the third day. Maximum physical exercise is swimming. On the third day after 3 hours of treatment (placebo or glutathione), then participants take a leukocyte profile measurement. The findings show that the number of leukocytes: K2> K1; P = 0.005; K2 - K3; P = 0.168; - K3; P 0.105, neutrophils: Kl, K2 and K3 are not different, even though K2 is highest, lymphocyte: K2> K1; P = 0.003, K1 - K3 and K2 - K3 is not different even though K2 is highest. The conclusion of this study is the number of leukocytes and lymphocytes treated with glutathione 54 mg / kg BW (K2) is significantly higher than K1 after strenuous physical exercise. Thus, the content of glutathione must be balanced with the body’s needs so that the body is healthy and is able to do the heavy activities.

scholarly journals Pengaruh pemberian vitamin E terhadap kadar neutrofil setelah latihan fisik

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Kristo Warong ◽  
Damajanty H.C. Pangemanan ◽  
Joice N.A. Engka
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Physical Exercise ◽  
Tissue Injury ◽  
The Body ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Test Control

Absract: Physical exercise can improve and maintain physical fitness. However, physical exercise can lead to oxidative stress that can reduce the activity of antioxidants. Vitamin E is a fat-soluble antioxidant that could free radicals in the body. Neutrophils play an active role in the process of phagocytosis of bacteria and other microorganisms the damaged tissue caused by tissue injury. This study was aimed to obtain the effect of vitamin E on neutrophil count after physical exercise. This was a field experimental study with a pre post test control group design. Data were analyzed with the Mann Whitney U (α = 0.05). The physical exercise was playing futsal for 60 minutes. Respondents were 30 male respondents divided into 2 groups: treatment and control groups. The levels of neutrophils were examined after physical exercise and after the administration of vitamin E 400 IU for seven days. Data analysis of the effect of vitamin E on neutrophil level after physical exercise showed a p value of 0.031. Conclusion: Vitamin E influenced the levels of neutrophils after physical exercise.Keywords: physical exercise, oxidative stress, vitamin E, neutrophil Abstrak: Latihan fisik merupakan aktivitas yang dilakukan seseorang untuk meningkatkan atau memelihara kebugaran tubuh. Latihan fisik dapat menimbulkan stres oksidatif sehingga dapat menurunkan aktivitas antioksidan. Vitamin E merupakan antioksidan yang larut dalam lemak dan berfungsi untuk mengurangi radikal bebas yang terdapat dalam tubuh. Neutrofil berperan aktif dalam proses fagositosis bakteri, mikroorganisme, dan membersihkan sisa jaringan rusak yang disebabkan oleh cedera jaringan. Penelitian ini bertujuan untuk mengetahui pengaruh vitamin E terhadap kadar neutrofil setelah latihan fisik. Jenis penelitian ialah eksperimental lapangan dengan pre post test control group design. Untuk menguji signifikansi penelitian digunakan uji Mann Whitney U (α = 0,05). Latihan fisik berupa olahraga futsal selama 60 menit dilakukan oleh 30 responden laki-laki yang dibagi dalam 2 kelompok yaitu perlakuan dan kontrol. Kadar neutrofil diukur setelah latihan fisik dan setelah pemberian vitamin E 400 IU selama 7 hari. Hasil statistik menunjukkan terdapat pengaruh bermakna dari vitamin E pada kelompok perlakuan (p=0,031). Simpulan: Terdapat pengaruh vitamin E terhadap kadar neutrofil setelah latihan fisik. Kata kunci: latihan fisik, stres oksidatif, vitamin E, neutrofil

scholarly journals Pengaruh Pembatasan Asupan Makan Wanita Obesitas Pre-Menopause Terhadap Kadar Trigliserida Dan Status Resistensi Insulin

2020 ◽  
Vol 9 (1) ◽  
pp. 18
Author(s):  
Fika Shafiana Nadia ◽  
Desti Ambar Wati ◽  
Muflihah Isnawati ◽  
Muhammad Sulchan ◽  
Diana Nur Afifah
Keyword(s):  
Insulin Resistance ◽  
The Body ◽  
Control Group ◽  
Obese Women ◽  
Control Group Design ◽  
Group Design ◽  
Paired Samples ◽  
Significant Difference ◽  
Before And After ◽  
Randomized Control

Penelitian ini bertujuan untuk mengetahui pengaruh pembatasan makanan terhadap kadar trigliserida dan status resistensi insulin pada wanita obesitas pre-menopause dengan menggambarkan karakteristik responden berdasarkan usia dan aktivitas fisik. Rancangan penelitian pre-post randomized control group design pada 20 orang wanita obesitas pre-menopause yang diberikan perlakuan pembatasan asupan makan isokalori 30 kkal/kgBB/hari. Uji Indeks Massa Tubuh atau IMT, asupan makan, kadar trigliserida dan status resistensi insulin sebelum dan sesudah perlakuan dilakukan dengan menggunakan uji paired samples test. Hasil penelitian menunjukkan bahwa terdapat perbedaan signifikan terhadap IMT; asupan energi; asupan protein; asupan lemak; kadar trigliserida, dan status resistensi insulin namun tidak terdapat perbedaan signifikan terhadap asupan karbohidrat sebelum dan sesudah perlakuan. Kesimpulannya, pembatasan asupan berpengaruh terhadap penurunan kadar trigliserida dan status resistensi insulin.Restriction effect on Eating Intake of Pre-Menopausal Obese Women against Triglyceride Levels dan Insulin Resistance StatusAbstractThis study aims to determine the influence of food restriction on triglyceride levels and insulin resistance status in pre-menopause obese women by describing the characteristics of respondents based on age and physical activity. Pre-post randomized control group design was used as experimental study using 20 pre-menopause obese women. The participants received the restriction of their intake as 30 kcal/kgW/day. The Body Mass Index or BMI, food intake, triglyceride levels and insulin resistance were tested before dan after the treatment using test paired samples test. The results showed that there was significant differences on BMI; energy intake; protein intake; fat intake; triglyceride levels, dan insulin-resistance status but there was no significant difference on carbohydrate intake at before and after treatment. The study concluded that intake restriction resulted in the decrement of triglyceride levels and insulin resistance status.

scholarly journals Efektivitas Ekstrak Bawang Merah (Allium ascalonicum L) Terhadap Penurunan Suhu Tubuh Anak dengan Demam Pasca Imunisasi DPT Pentabio

2021 ◽  
Vol 11 (1) ◽  
pp. 6
Author(s):  
Setiawandari Setiawandari ◽  
Eka Deviany Widyawaty
Keyword(s):  
Body Temperature ◽  
Hepatitis B ◽  
The Body ◽  
Control Group ◽  
P Value ◽  
Type B ◽  
Control Group Design ◽  
Group Design ◽  
Influenza Type ◽  
Post Test

The immunizations that must be given to children include the Diphtheria Pertussis Tetatus-Hepatitis B-Hemophilus Influenza type B vaccine or better known as Pentabio DPT. The DTwP / HB / HiB vaccine is given to babies in 3 doses at 1 month intervals. This immunization caused a systemic reaction, one of which was a fever of 0.85% in the first 30 minutes and increased to 14.03% on the day after immunization. The purpose of this study was to determine the effectiveness of shallots (Allium ascalonicum L) in reducing the body temperature of feverish children after Pentabio DPT immunization. This type of research was quasi-experimental study, with pre and post test with control group design. The sample in this study were babies who received DPT immunization as many as 20 respondents. DPT Pentabio immunization was given a dose of 0.5 ml in the intervention group and the control group. The statistical test used was the T test. The results showed that there was a significant effect of shallots on in reducing the body temperature of feverish children after Pentabio DPT immunization, with a p-value of 0.000. Keywords: shallots; body temperature; fever; Pentabio DPT immunization ABSTRAK Imunisasi yang wajib diberikan kepada anak-anak diantaranya adalah vaksin Diphtheria Pertusis Tetatus-Hepatitis B-Hemophilus Influenza type B atau lebih dikenal dengan DPT Pentabio. Vaksin DTwP/HB/HiB diberikan kepada bayi sebanyak 3 dosis dengan interval 1 bulan. Imunisasi ini menimbulkan reaksi sistemik salah satunya berupa demam 0,85% pada 30 menit pertama dan meningkat menjadi 14,03% pada satu hari pasca imunisasi. Tujuan dari penelitian ini adalah mengetahui efektifitas bawang merah (Allium ascalonicum L) terhadap penurunan suhu tubuh anak demam pasca imunisasi DPT Pentabio. Jenis penelitian quasi eksperimen dengan pre and post test with control group design. Sampel pada penelitian ini adalah bayi yang mendapat imunisasi DPT sebanyak 20 orang responden. Pemberian imunisasi DPT PENTABIO Pentabio dosis 0,5 ml pada kelompok intervensi dan kelompok kontrol. Uji statistik yang digunakan adalah Uji T. Hasil penelitian menunjukkan ada pengaruh yang signifikan dari bawang merah dalam menurunkan suhu tubuh anak demam pasca imunisasi DPT Pentabio, dengan p-value 0,000. Kata kunci: bawang merah; suhu tubuh; demam; imunisasi DPT Pentabio

scholarly journals Efektivitas Klinis Ofloksasin Topikal Dibanding Ciprofloksasin Oral Pada Terapi Otitis Media Supuratif Kronik Aktif

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Deasy Mediawaty ◽  
Pujo Widodo ◽  
Dian Ayu Ruspita
Keyword(s):  
World Health Organization ◽  
Otitis Media ◽  
Randomized Control Trial ◽  
World Health ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Randomized Control ◽  
Health Organization ◽  
Per Oral

Latar belakang : Otitis media kronik atau sering disebut Otitis Media Supuratif Kronik (OMSK) adalah otitis media yang berlangsung > 12 minggu. Prevalensi OMSK di seluruh dunia sebanyak 65-330 juta dan 60% di antaranya menderita kurang pendengaran yang signifikan. Angka kejadian OMSK aktif mencapai 3,8% dari pasien THT-KL. Gejala OMSK aktif berupa banyaknya discaj, kurang pendengaran, nyeri, pusing berputar, telinga tidak nyaman. Tanda OMSK aktif berupa discaj di liang telinga, perforasi membran timpani, dan gangguan pendengaran. World Health Organization (WHO) mencanangkan strategi untuk mengatasi OMSK secara serius berkaitan dengan komplikasi yang dapat disebabkan. Pilihan terapi medikamentosa yang tepat diperlukan untuk mengatasi OMSK aktif. Ofloksasin topikal dan ciprofloksasin oral adalah antibiotik golongan fluorokuinolon yang banyak digunakan. Efektivitas diantaranya dibuktikan dengan perbaikan gejala dan tanda klinis. Tujuan : Membuktikan efektifitas ofloksasin topikal, ciprofloksasin oral dan efektifitas ofloksasin topikal dibanding ciprofloksasin oral terhadap perbaikan gejala dan tanda klinis. Metode :  Penelitian intervensi dengan rancangan pretest and posttest control group design, randomized control trial Klinik THT-KL BKIM Semarang pada bulan Juni-Agustus 2016. Penderita OMSK aktif dilakukan anamnesis lalu dilakukan pemeriksaan fisik dan pemeriksaan pendengaran dilanjutkan randomisasi. Penderita diberi ofloksasin topikal 10 tetes/12 jam atau ciprofloksasin tablet 500 mg/12 jam per oral. Hari ke 4, 10 dan 14 setelah terapi penderita kontrol. Analisis uji komparatif menggunakan uji parametrik dan non parametrik. Hasil : Jumlah subyek penelitian 108 orang ; ofloksasin topikal 54 orang (50%) dan ciprofloksasin oral 54 orang  (50 %). Gejala dan tanda klinis setelah terapi lebih rendah dibanding sebelum terapi pada kelompok ofloksasin topikal dan ciprofloksasin oral dengan nilai kemaknaan p < 0,05. Gejala klinis kelompok ofloksasin lebih baik dibanding ciproloksasin secara bermakna (p<0,05). Tanda klinis kedua kelompok terdapat perbedaan yang tidak bermakna (p>0,05). Simpulan : Ofloksasin topikal dan ciprofloksasin oral terbukti efektif memperbaiki gejala dan tanda klinis penderita OMSK aktif. Ofloksasin topikal efektif memperbaiki gejala klinis dibandingkan ciprofloksasin oral. Kata kunci : Otitis media supuratif kronik, ofloksasin, ciprofloksasin, gejala dan tanda klinis

scholarly journals PENGARUH PEMBERIAN PISANG KEPOK (Musa Paradisiaca Forma Typical) TERHADAP KADAR TRIGLISERIDA TIKUS SPRAGUE DAWLEY PRA SINDROM METABOLIK

2015 ◽  
Vol 4 (4) ◽  
pp. 585-592
Author(s):  
Rusdaina Rusdaina ◽  
Ahmad Syauqy
Keyword(s):  
T Test ◽  
Control Group ◽  
Sprague Dawley ◽  
Control Group Design ◽  
Group Design ◽  
Musa Paradisiaca ◽  
Randomized Control ◽  
Paired T Test

Latar Belakang : Prevalensi pra sindrom metabolik meningkat di negara maju dan berkembang. Faktor risiko pra sindrom metabolik salah satunya ialah hipertrigliseridemia. Serat prebiotik seperti inulin dan pati resisten mampu menurunkan kadar trigliserida. Inulin dan pati resisten terdapat dalam buah pisang seperti pisang kepok (Musa paradisiaca forma typical). Penelitian ini bertujuan untuk mengkaji pengaruh pisang kepok (Musa paradisiaca forma typical) terhadap kadar trigliserida tikus Sprague Dawley pra sindrom metabolik.Metode : Penelitian ini merupakan true experimental dengan pre-posttest randomized control group design yang menggunakan 28 ekor tikus jantan Sprague Dawley. Pengelompokan dilakukan secara acak menjadi 4 kelompok: kelompok K(-) (hanya diberi pakan standar), K(+) (diberi pakan standar dan induksi STZ), P1 dan P2 (diberi pakan standar, induksi STZ dan pisang kepok (Musa paradisiaca forma typical) dengan dosis masing-masing 4,5 dan 9 gram selama 3 minggu). Data dianalisis dengan paired t-test dan Kruskal Wallis.Hasil : Pisang kepok (Musa paradisiaca forma typical) dengan dosis masing-masing 4,5 dan 9 gram dapat menurunkan kadar serum trigliserida dari 83,6 ± 9,70 mg/dl menjadi 66,2 ± 4,85 mg/dl dan 79,2 ± 6,76 mg/dl menjadi 47,2 ± 4,42 mg/dl, secara berturut-turut (p<0,05). Perubahan kadar trigliserida pada kelompok K(-), K(+), P1 dan P2, secara berturut-turut 1 (p=0,001); 12 (p=0,005);  -17,4 (p=0,007); dan -31,99 (p=0,000).Simpulan : Pemberian pisang kepok (Musa paradisiaca forma typical) dengan dosis 9 g/200 g BB tikus/hr mampu menurunkan kadar serum trigliserida lebih tinggi (p=0,000) sekitar 40,4%.

PENGARUH MENGKONSUMSI GULA AREN (Arenga pinnata) SEBELUM OLAHRAGA TERHADAP DAYA TAHAN OTOT

2019 ◽  
Vol 1 (1) ◽  
pp. 20
Author(s):  
Cecep Muhammad Alawi ◽  
Hamidie Ronald Daniel Ray
Keyword(s):  
Physical Exercise ◽  
Significant Influence ◽  
The Body ◽  
Control Group ◽  
Muscular Endurance ◽  
Control Group Design ◽  
Squat Jump ◽  
Jump Test ◽  
Significant Difference ◽  
Palm Sugar

Two kinds of carbohydrates that are used with the body as energy, is blood glucose and muscular glycogen. Savings glycogen in muscular is one of the factors that is affecting muscular endurance when physical exercise. The aim of this study is to find out the significant influence of consuming palm sugar to muscular endurance before physical exercise. The method that is used in this study is to experiment with design pretest-posttest control group design. Total of sample of this study is 18 trained mans that is divided into three groups. The first experiment group is given palm sugar that is dissolved in water, the second experiment group is given sugar that is dissolved in water, and the control group is given mineral water. The instrument of this study is used push up test, sit up test, and squat jump test to measures the upper muscular endurance, middle, and bottom. All of the samples have done pretest and posttest in different day. When posttest, all of the sample is consumed beverage based on the treatment 30 minutes before do the posttest. Data analysis by Paired Sample t-test and continued by One Way ANOVA to see the influence and comparison between groups. The result of this study has showed that there is a significant difference, the raising of muscular endurance is proved by the score (sig) 0.00>0.05, which the highest increasing is the palm sugar group. Therefore, it could be concluded that there is a significant influence of consuming palm sugar to muscular endurance before physical exercise.

scholarly journals PEMBERIAN TERAPI MURATTAL AL-QURAN TERHADAP KUALITAS TIDUR IBU HAMIL PRIMIGRAVIDA TRIMESTER III

2021 ◽  
Vol 7 (2) ◽  
pp. 287-294
Author(s):  
Noviyanti Noviyanti ◽  
Rahmi Rahmi ◽  
Ratna Dewi ◽  
Nurdahliana Nurdahliana
Keyword(s):  
Treatment Group ◽  
Sleep Quality ◽  
Pregnant Women ◽  
Wilcoxon Test ◽  
Control Group ◽  
Third Trimester ◽  
Control Group Design ◽  
Group Design ◽  
The Third

GIVING MURATTAL AL-QURAN THERAPY ON QUALITY TRIMESTER PRIMARY PREGNANT MOTHER'S SLEEP III Background : Expecting mothers experienced different discomforts which were frequently felt in the third trimester, a waiting period in which the pregnant mothers started to be alert of delivering a baby. These discomforts resulted in disturbance of activities of the expectants. Sleep problem was mostly occured during this trimester which might decrease sleep quality. To overcome the complaint, there should be a way to increase sleep quality of the pregnant women. One of them is Murattal Qur'an.Purpose : This study was aimed at finding out the effect of Murattal Qur'an on third semester toward sleep quality of the pregnants.Methods : This research belonged to a quasi-experimental with a pretest-posttest control group design. The population in this study were all pregnant women in the third trimester primigravida in the working area of the Kuta Baro Health Center, Aceh Besar. The sample was 40 pregnant women who were divided into the control group and the treatment group. The treatment group listened to the Murattal Quran chapter Ar-Rahman on Android for 7 nights before going to bed. Data was  analysed by using the Wilcoxon test because the data were not normally distributed.Results : The obtained significant value (p) of  the treatment group of before and after  therapy was  0.000 lower than 0.05 (p=0.000 <0.05)Conclusion : There is an effect of giving Murattal Al-Quran therapy in the third trimester primigravida on the quality of mother's sleep.Suggestion : It hoped that it increased the active role of Midwives to provide information to pregnant women about the way to overcome the sleep disorders of   the third trimester pregnant women was by by listening to the murattal Quran. Keywords: Murattal Al-Quran, Sleep Quality, Primigravida, Third Trimester.ABSTRAK Latar Belakang :  Ketidaknyamanan yang dirasakan oleh ibu hamil paling sering dirasakan saat trimester III. Trimester III merupakan masa menunggu kelahiran bayinya. Ketidaknyamanan yang dirasakan ibu mengakibatkan aktivitas sehari-hari ibu hamil menjadi terganggu. Gangguan tidur merupakan Keluhan yang paling sering terjadi pada ibu hamil trimester III. Gangguan ini menyebabkan kualitas tidur ibu menurun. Salah satu cara pendekatan untuk meningkatkan kualitas tidur ibu hamil adalah mendengarkan lantunan ayat Al-Quran.Tujuan : Mengetahui pengaruh pemberian terapi murattal Al-Quran pada primigravida trimester III terhadap kualitas tidur ibu.Metode : Jenis penelitian adalah quasi-eksperimen dengan pendekatan pretest-posttest control group design. Populasi adalah primigravida trimester III di wilayah kerja Puskesmas Kuta Baro Kabupaten Aceh Besar. Jumlah sampel 40 ibu hamil yang dibagi menjadi kelompok kontrol dan kelompok perlakuan. Kelompok perlakuan mendengarkan murattal Al-Quran surah Ar-Rahman dengan menggunakan HP Android selama 7 malam sebelum tidur. Analisa data menggunakan Uji Wilcoxon karena data berdistribusi tidak normal.Hasil :  Nilai signifikan pada kelompok perlakuan terhadap kualitas tidur ibu sebelum dan sesudah diberikan terapi adalah p = 0,000 lebih kecil dari nilai 0,05.Kesimpulan : Terdapat pengaruh pemberian terapi murattal Al-Quran pada primigravida trimester III terhadap kualitas tidur ibu.Saran : Meningkatkan peran aktif bidan dalam memberikan informasi kepada ibu hamil tentang asuhan ketidaknyaman ibu hamil trimester III yaitu masalah gangguan tidur dengan mendengarkan murattal Al-Quran.  Kata Kunci: Murattal Al-Quran, Kualitas tidur, Primigravida, Trimester III. 

scholarly journals Pengaruh Pemberian Susu Coklat Terhadap Kadar F2Isoprostan pada Siswa di Pusat Pendidikan dan Latihan Olahraga Pelajar (PPLP) Sumatera Barat

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Dezi Ilham ◽  
Afriwardi Afriwardi ◽  
Eti Yerizel
Keyword(s):  
Free Radicals ◽  
Treatment Group ◽  
Physical Exercise ◽  
T Test ◽  
The Body ◽  
Control Group ◽  
Milk Chocolate ◽  
Control Group Design ◽  
Paired Sample ◽  
Before And After

Abstrak Latihan fisik yang berlebihan dapat meningkatkan produksi radikal bebas di dalam tubuh. Peningkatan radikalbebas ini kalau tidak dinetralisasi oleh antioksidan di dalam tubuh, maka terjadilah stres oksidatif yang dapatmenyebabkan terjadinya peroksidasi lipid, sehingga menghasilkan produk senyawa F2-isoprostan yang dapatberdampak terhadap berbagai masalah kesehatan. Tujuan penelitian ini adalah untuk menentukan pengaruhpemberian susu coklat terhadap kadar F2-isoprostan. Penelitian ini merupakan eksperimental pre and post test controlgrup design terhadap 36 siswa atlet, yang memenuhi kriteria inklusi dan ekslusi. Subjek dibagi dua kelompok yaituyang diberikan perlakuan susu coklat dan kontrol susu putih. Susu diminum setelah latihan fisik rutin atlet sebanyaksatu kali sehari selama 15 hari. Kadar F2-isoprostan dinilai sebelum dan sesudah secara ELISA. Data dianalisisdengan paired sample t-Test, bermakna bila p<0,05. Hasil penelitian didapatkan rerata kadar F2-isoprostan sebelumperlakuan pada kelompok susu coklat adalah 65,98±14,61 pg/ml dan sesudah perlakuan adalah 45,55±13,74 pg/ml.Rerata kadar F2-isoprostan sebelum perlakuan pada kelompok kontrol susu putih adalah 54,24±20,44 pg/ml dansesudah perlakuan adalah 48,80±20,23 pg/ml. Kesimpulan yang diperoleh ada pengaruh yang bermakna dari reratakadar F2-isoprostan sebelum dan sesudah perlakuan baik pada kelompok perlakuan susu coklat dan kelompok kontrolsusu putih.Kata kunci: latihan fisik, radikal bebas, F2-isoprostan, susu coklatAbstract Excessive physical exercise can increase the production of free radicals in the body. The increase in freeradicals if not neutralized by antioxidants in the body and it caused oxidative stress which can cause lipid peroxidation,resulting in F2-isoprostane product compounds that can affect a variety of health problems. The objective of this studywas to determine the influence of milk chocolate on F2-isoprostane levels. This study was an experimental pre andpost test control group design to the 36 student athletes, who meet the inclusion and exclusion criteria. The subjectswere divided in two groups: the treatment given milk chocolate and white milk is given control, drunk after a routinephysical exercise athlete, once a day for 15 days. F2-isoprostane levels were assessed before (pre) and after (post) byELISA, the data were analyzed by Paired Sample t-Test, significant if p <0.05. The results showed average levels ofF2-isoprostane before treatment group was 65.98 ± chocolate milk 14.61 pg / ml and after treatment was 45.55 ±13.74 pg / ml. Average F2-isoprostane levels before treatment in the control group was 54.24 ± white milk 20.44 pg /ml and after treatment was 48.80 ± 20.23 pg / ml. There is a significant influence on the mean levels of F2-isoprostaneboth before and after treatment in the treatment group and the control group of milk chocolate and white milkKeywords: physical exercise, free radicals, f2-isoprostane, milk chocolate

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