scholarly journals Identification of risk factors for death from tetanus in Pernambuco, Brazil: a case-control study

2000 ◽  
Vol 42 (6) ◽  
pp. 333-339 ◽  
Author(s):  
Demócrito B. MIRANDA-FILHO ◽  
Ricardo A.A. XIMENES ◽  
Silvya N. BERNARDINO ◽  
Abelardo G. ESCARIÃO
Keyword(s):  
Risk Factors ◽  
Medical Records ◽  
Case Control Study ◽  
Artificial Ventilation ◽  
Case Control ◽  
The State ◽  
University Hospital ◽  
State University ◽  
Neck Stiffness ◽  
Control Study

A case-control study was conducted to identify risk factors for death from tetanus in the State of Pernambuco, Brazil. Information was obtained from medical records of 152 cases and 152 controls, admitted to the tetanus unit in the State University Hospital, in Recife, from 1990 to 1995. Variables were grouped in three different sets. Crude and adjusted odds ratios, p-values and 95% confidence intervals were estimated. Variables selected in the multivariate analysis in each set were controlled for the effect of those selected in the others. All factors related to the disease progression - incubation period, time elapsed between the occurrence of the first tetanus symptom and admission, and period of onset - showed a statistically significant association with death from tetanus. Similarly, signs and/or symptoms occurring on admission or in the following 24 hours (second set): reflex spasms, neck stiffness, respiratory signs/symptoms and respiratory failure requiring artificial ventilation (third set) were associated with death from tetanus even when adjusted for the effect of the others.

Association between Neuroleptics and Venous Thromboembolism: A Case-Control Study.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 2601-2601
Author(s):  
Karine Lacut ◽  
Gregoire Le Gal ◽  
Emmanuel Oger ◽  
Dominique Mottier
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Antipsychotic Drugs ◽  
Case Control Study ◽  
Case Control ◽  
University Hospital ◽  
Number Of Patients ◽  
Increased Risk ◽  
Significant Difference ◽  
Control Study

Abstract Background: Preliminary reports suggest that use of antipsychotic drugs is associated with an increased risk of venous thromboembolism (VTE), but others did not confirm these results. Objective: To evaluate the relationship between antipsychotic drugs and VTE. Design: Case-control study (EDITH) designed to investigate genetic and environmental risk factors of VTE. Setting: Brest University Hospital. Participants: 857 patients consecutively hospitalized for a documented venous thromboembolic event were included between May 2000 and May 2004. Controls were matched on age, sex and the main risk factors of venous thromboembolism (cancer, surgery, pregnancy…). Results: The mean age of patients was 67.7 year. No significant difference was found between cases and controls concerning the main characteristics, except for smocking and body mass index. Among cases, 89 (10.4%) were current users of neuroleptics compared to 35 (4.8%) among controls. Current use of neuroleptics was associated with a significant increased risk of venous thromboembolism (OR = 2.32, 95% CI: 1.55–3.48). Excluding neuroleptics used for non psychiatric disorders, and after adjustment on the main confounding factors, this association remained significant (OR = 3.48, 95% CI: 2.00–6.04). No difference was found between the different chemical categories of neuroleptics, but the number of patients in some groups had limited statistical power to demonstrate significant differences. Biological mechanisms of action have been proposed to explain this relation. Analyses are ongoing for anti-phospholipid antibodies and homocysteine. Conclusion: In this case-control study of hospitalized patients, neuroleptics use was associated with a significant increased risk of venous thromboembolism. These results are concordant with previous reports. Nevertheless, further investigations are needed to explain wich mechanisms may be involved in such association and before use of neuroleptics can be definitely considered as risk factor for venous thromboembolism.

scholarly journals The assessment of risk factors for the Central/East African Genotype of chikungunya virus infections in the state of Kelantan: a case control study in Malaysia

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Ahmad Faudzi Yusoff ◽  
Amal Nasir Mustafa ◽  
Hani Mat Husaain ◽  
Wan Mansor Hamzah ◽  
Apandi Mohd Yusof ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chikungunya Virus ◽  
Case Control Study ◽  
Case Control ◽  
The State ◽  
Virus Infections ◽  
East African ◽  
Control Study

scholarly journals Observations and analysis of risk factors for GDV in a single institution: a case-control study

2020 ◽  
Vol 2 (1) ◽  
pp. 16-40
Author(s):  
Fabrizio di Virgilio ◽  
Emanuela Rabaioli ◽  
Massimo Gualtieri ◽  
Luca Formaggini
Keyword(s):  
Risk Factors ◽  
Medical Records ◽  
Case Control Study ◽  
Case Control ◽  
Evidence Based ◽  
Single Institution ◽  
Referral Centre ◽  
Purebred Dogs ◽  
And Control ◽  
Control Study

Objective To evaluate/ determine the risk factors for dogs presented with Gastric Dilation- Volvulus (GDV) to a referral veterinary centre and to compare the results with those currently reported in veterinary literature. Materials and Methods The observational case-control study comprised a population of 215 dogs that attended the referral centre between 2000 and 2018. Medical records were searched for GDV and those matching the criteria were manually reviewed. A questionnaire was completed by the owners of the dogs involved in the study (both case and control populations) in order to gain further information that could be considered relevant to GDVs. In particular, information included the dogs’ behaviour and the dogs daily activities. Results The study included 115 cases of GDV and 115 controls. Out of the GDV dogs 13% (15/115) were small breed dogs and the remaining 87% (100/115) either large or giant breeds. The following risk factors for developing a GDV have been identified: Purebred dogs over 3 years old and either large of giant breeds, weighing > 30 kg. Foreign body ingestion, diarrhoea, and grass consumption were also associated to increase the likelihood in developing GDV. Behavioural temperament was not associated with developing GDV. Clinical Significance The findings support previously identified risk factors in the development of GDV, but characteristics related to the dogs temperament warrant further investigation. Knowledge of these results will further allow clinicians to make evidence‐based recommendations to owners in attempting to prevent GDV in dogs. Furthermore this paper confirms that the risk of GDV in certain breeds and in certain conditions is always high and that GDV is still an extremely current disease.

scholarly journals Behavioural, Nutritional and Genetic Risk Factors of Colorectal Cancers in Morocco: Protocol for a Multicentre Case-Control Study

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 197s-197s
Author(s):  
K. El Rhazi ◽  
I. Huybrechts ◽  
M. Mint Sidi Deoula ◽  
K. El Kinany ◽  
R. Bakkali ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Dietary Habits ◽  
Energy Requirement ◽  
Case Control ◽  
University Hospital ◽  
Control Group ◽  
Cancer Risk Factors ◽  
Moroccan Population ◽  
Control Study

Background: Colorectal cancer (CRC) is the third most common cancer in men and the second in women worldwide and its risk factors are complex. Genetic and environmental factors are strongly involved including lifestyle and eating habits. In Morocco, the number of new CRC cases is increasing. In parallel, cancer risk factors and behaviors of the Moroccan population are changing due to profound societal and technical changes. Aim: To that end we designed a multicenter case control study that aimed to evaluate the relationship between dietary habits, physical activity, genetics factors and the risk of CRC in Moroccan population. Methods: This case control study was conducted between January 2009 and February 2017 in 5 major University Hospital Centers in Morocco (Fez, Rabat, Oujda, Casablanca and Marrakech). Cases were matched with controls by age (±5 years), sex and center. Participants completed a face-to-face questionnaire on sociodemographic data, lifestyle, family history of CRC and no steroidal anti-inflammatory drugs. In addition, participants completed a semiquantitative food-frequency questionnaire (FFQ) was developed to assess food intake in the Morocco population. Pathology tumor samples were collected for 200 cases. For genetic data analysis, DNAs were extracted by manually scraping tissue from unstained slides. To assess the strength of the association between characteristics and the risk of CRC, odds ratios (OR) with 95% confidence intervals were estimated by conditional regression models. All statistical analyses were done using SPSS v20. Results: In total, 3032 pairs (1516 cases and 1516 controls) were recruited. Excluded participants (case/control) were unspecified primitive cancer (7 pairs), participants with missing dietary data (26 pairs) and participants with the lowest and highest 1% of the distribution of the ratio between energy intake and energy requirement (30 pairs). All together, 2906 cases and controls were recruited during the study period. Both cases and controls did not differ significantly with respect to sex 50.7% were women and 49.3% were men ( P = 0.51), the center that recruited the most was Rabat, followed by Casablanca, Oujda, Fez, and finally Marrakech ( P = 1.00). For marital status, being married was most frequent for both cases and controls (76.3% vs 77.0%) ( P = 0.36), alcohol consumption was higher in cases than controls (2.4% vs 1.7%) ( P = 0.12). However, participants in the control group were significantly more moderately active (58.4% vs 52.1%) and more likely to be never smoker (83.8% vs 77.6%). Conclusion: This study is the first large one that has described the risk factors of CRC in Morocco and in North Africa. It gives for the first time results about these risk factors which are drawn directly from this target population. Preventive recommendations could, therefore, be reviewed and adapted to these populations accordingly.

scholarly journals Faktor risiko kematian akibat dengue di RSUP Dr. Sardjito Yogyakarta

2018 ◽  
Vol 34 (1) ◽  
pp. 1
Author(s):  
Ruri Trisasri ◽  
Eggi Arguni ◽  
Riris Andono Ahmad
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Dengue Hemorrhagic Fever ◽  
Medical Records ◽  
Family Income ◽  
Case Control Study ◽  
Hemorrhagic Fever ◽  
Case Control ◽  
Probability Of Death ◽  
Control Study

Purpose:We examined risk factors of dengue hemorrhagic fever death in Sardjito hospital. Method: We conducted case control study from patient medical records and interview with parents. Results: We found 29 deaths and 58 survived. The probability of death in obesity children was 6.29 times higher than non obesity children and the probability of death in children with prolonged shock was 12.14 times higher than children without prolonged shock. Other variables were family occupation, family income, residential zones, transportation, treatment financing, accuracy of diagnosis in previous health facilities, and fluid resuscitation before being referred has no significant relationship with dengue mortality. Conclusion: Obesity and prolonged shock were risk factors of dengue hemorrhagic fever death in children. Improve education to parents about high risk of shock syndrome among patients, especially for obesity children. Further studies related to social determinants in dengue hemorrhagic fever death are also necessary.

scholarly journals Commuting Accidents among Non-Physician Staff of a Large University Hospital Center from 2012 to 2016: A Case-Control Study

2020 ◽  
Vol 17 (9) ◽  
pp. 2982
Author(s):  
Alexandre Ponsin ◽  
Emmanuel Fort ◽  
Martine Hours ◽  
Barbara Charbotel ◽  
Marie-Agnès Denis
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
University Hospital ◽  
Multiple Model ◽  
Work Related ◽  
Increased Risk ◽  
Gender And Age ◽  
Control Study

Road risks (commuting and on-duty accidents) have been responsible for 44% of work-related fatalities compensated by the French system of Social Security in 2012 and still represented 37% in 2018. Our objective was to assess risk factors for commuting accidents among the non-physician staff in a French university hospital. We conducted a case-control study of commuting accidents from 2012 to 2016. Cases were identified and controls were randomly selected from the hospital’s personnel file with matches by year of the accident, gender and age. Risk factors were assessed using conditional logistic regression analysis. An increased risk was observed for 2 × 8 hour shifts, crude OR = 1.40 (95% CI = 1.05–1.86) compared to daytime schedules, but not confirmed in the multiple model. Being a duty officer and not working the day before the accident were associated with increased risk of accidents with adjusted OR = 1.9 (95% CI = 1.1; 3.3) and OR = 1.5, (95% CI = 1.1; 2.1), respectively. The risk increased as the distance between home and work increased, such as adjusted OR = 2.2 (95% CI = 1.4; 3.4) for a distance of >3.6 to 9 km, OR = 2.6, (95% CI = 1.7; 4.0) for a distance of >9 km to 19 km, and OR = 4.2, (95% CI = 2.8; 6.2) for >19 km vs. <3.6 km. The distance between home and work, not working the day before the accident, and certain categories of personnel were related to commuting accidents.

Risk Factors for Nosocomial Bacteremia in a Large Spanish Teaching Hospital: A Case-Control Study

1991 ◽  
Vol 12 (3) ◽  
pp. 150-156 ◽  
Author(s):  
Antoni Trilla ◽  
Josep M. Gatell ◽  
Josep Mensa ◽  
Xavier Latorre ◽  
Manuel Almela ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Strong Support ◽  
Case Control ◽  
Control Measures ◽  
University Hospital ◽  
Stepwise Logistic Regression ◽  
Infection Control Measures ◽  
Nosocomial Bacteremia ◽  
Control Study

AbstractObjective:Identify independent risk factors associated with the development of nosocomial bacteremia.Design:Exploratory, unmatched, case-control study.Setting:A 970-bed Spanish university hospital.Patients:All non-neutropenic adult patients with nosocomial bacteremia admitted during a 12-month period were eligible as cases. All adult non-neutropenic patients without nosocomial bacteremia were eligible as controls.Results:The incidence of bacteremia in the study population was 6.9/1000 admissions/ year. One hundred eighty cases and 180 controls were analyzed. Multivariate analysis (stepwise logistic regression techniques) identified seven risk factors independently associated with nosocomial bacteremia: age above 65 years; prior admission (within six months) to the hospital; underlying diseases that were ultimately or rapidly fatal; indwelling urethral catheter in place for more than three days; intravenous central lines or peripheral venous lines (if in place for more than four days); “high-risk surgery” (i.e., lower abdominal, cardiac or thoracic); and admission to an intensive care unit.Conclusions:Although five variables are not modifiable, the remaining two relate to the use and duration of devices. Our data give strong support for the value of testing strict guidelines for limiting vascular catheters and evaluating the need for prolonged urethral catheterization. If effective infection control measures are identified, we could target hospital-wide surveillance to patients whose risk factors are amenable to intervention.

Sign in / Sign up

Export Citation Format

Share Document