Relationship between habits and precancerous lesions of the oral cavity – a clinicopathological study

2021 ◽  
Vol 6 (1) ◽  
pp. 254-259
Author(s):  
Dr. Ajay Kumar Yadlapalli ◽  
◽  
Dr. B Krishna Santosh ◽  
Dr. Dwarampudi S K Reddy ◽  
Dr. Panda Veeranjaneyulu ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Clinical Presentation ◽  
Precancerous Lesions ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Premalignant Lesions ◽  
Cross Sectional ◽  
Oral Cancers ◽  
Reticular Pattern ◽  
Oral Malignancy

Introduction: Oral cancers account for 3% of total malignancies. A research was conducted to findthe incidence, age, and sex distribution, clinical presentation, and the relationship between habitsand various premalignant lesions of the oral cavity. Methods: It was a hospital-based observationaland cross-sectional study, conducted in GSL Medical College, Rajamahendravaram from October2015 to April 2017. Individuals aged > 18 years, with leukoplakia, erythroplakia, blanched mucosawith or without fibrous bands and /or trismus suggestive of oral submucous fibrosis, bilateral whitishlesions with a reticular pattern suggestive of lichen planus, and ulcer against sharp tooth denturesuggestive of traumatic dental ulcers were taken. Individuals with frank oral malignancy, those withterminal diseases, those who did not submit informed consent were not considered. Results: Themajority of patients (33.33%) were aged between 51 – 60 years, belong (62.75%) to lowersocioeconomic status. Leukoplakia (64.7%) was a common clinical presentation. Most (49.02%) ofthe study patients presented with a burning sensation. When addictions were considered, 86.27% ofpatients were smokers, 23.53% were addicted to alcohol. Conclusion: Leukoplakia was thecommonest (64.71%) premalignant lesion, 51 – 60 years was the common age group. Premalignantlesions were most commonly seen among males, most of the study participants belong to low andmiddle socio-economic groups with a rural background. Diabetes mellitus was the most commoncomorbidity associated with premalignant lesions.

scholarly journals Epidemiological profile of oral cancers in Benin

2020 ◽  
Vol 6 (2) ◽  
pp. 234
Author(s):  
Spéro H. Raoul Hounkpatin ◽  
Fatiou Alabi Bouraima ◽  
Marius Claude Flatin ◽  
Marie-Claire Balle ◽  
Luc Valere C. Brun
Keyword(s):  
Oral Cavity ◽  
Oral Cavity Cancer ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Malignant Tumours ◽  
Cross Sectional ◽  
Oral Cancers ◽  
Health Authorities ◽  
Epidemiological Profile ◽  
Common Histological Type

<p class="abstract"><strong>Background:</strong> The objective of the study was to study the epidemiological profile of malignant tumours of the oral cavity in Benin from January 2009 to 31 December 2014.</p><p class="abstract"><strong>Methods:</strong> This was a descriptive cross-sectional study that examined cancers of the oral cavity collected in the registers of the 5 anatomy and pathology laboratories in Benin as well as the only hospital in the country that sends its requests for histological examinations abroad.  </p><p class="abstract"><strong>Results:</strong> With a rate of 19.8%, oral cavity cancer was the most frequent cancer localization in the ENT, head and neck sphere in Benin. The most frequent sites of cancers in the oral cavity were the palate (32.2%) followed by the tongue (25.4%) and the inner face of the cheeks (16.9%). The average age of the patients was 53.18±20.60 years with extremes of 1 year and 90 years. The sex ratio was 0.90. Squamous cell carcinoma was the most common histological type with 67.80%.</p><p class="abstract"><strong>Conclusions:</strong> Cancer of the oral cavity must be a priority for health authorities in Benin. Research must be initiated to determine the factors that contribute to it.</p>

scholarly journals Clinical profile and oral sub mucous fibrosis

2017 ◽  
Vol 5 (1) ◽  
pp. 5-7
Author(s):  
Rishi Bhatta ◽  
M. Pyakurel
Keyword(s):  
Oral Cavity ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Betel Quid ◽  
Cross Sectional ◽  
Medical College ◽  
Dependent Relationship ◽  
Submucous Fibrosis ◽  
Dose Dependent

Objectives: Oral submucous fibrosis (OSMF) is an insidious precancerous disease mostly seen in the Southeast Asia. This paper aims to study on clinical profile of patients with OSMFMaterial and Methods: This cross sectional study was done in department of ENT and HNS, Nepalgunj Medical College and Teaching Hospital. In outpatient department patients with OSMF were ask to fill up a questionnaire that included identification of patient, occupation, their symptoms and habit of taking betel quid or paan, gutkha, etc. Oral cavity was examined and lesion along with its extent and severity was noted. Intra lesional steroid and antioxidant and physiotherapy were main stay of treatment.Results: There were total 136 patients (98 male and 38 female) from 15th Dec 2013 to 15th Jan 2015. Age of patient ranged from 16 years to 53 years and average being 25.6years. Most common preparation taken was gutkha 131(96.3%) followed by betel nut, betel quid etc. Only 24(17.6%) were taking these preparations for less than 1 year. Common presenting complaints were difficulty in opening mouth followed by burning sensation and dryness of mouth. Clinically, the extent of fibrous band was found to be more commonly involving soft palate, pillars and buccal mucosa. Isolated involvement of different region of oropharynx or oral cavity was less common. Correlation of grade of trismus and average duration of taking these different preparations was highly significant. (p=0.008)Conclusions: Oral submucous fibrosis is commonly associated with intake of gutkha having dose dependent relationship with trismus. Further studies are required why only a small fraction of those using betel quid develop the disease.  

scholarly journals Oral cancer awareness among students from Mumbai University

2018 ◽  
Vol 7 (7) ◽  
pp. 1215
Author(s):  
Dnyanesh Limaye ◽  
Gauri Bhatkhande ◽  
Shweta Sabu ◽  
Aashvi Jain ◽  
Poorva Taskar ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Undergraduate Curriculum ◽  
Cross Sectional Study ◽  
Good Knowledge ◽  
Cancer Awareness ◽  
Cross Sectional ◽  
Oral Cancers ◽  
Almost All

Background: Oral cancer is among the top three types of cancers in India. Severe alcoholism, use of tobacco in the form of cigarettes, smokeless tobacco, and betel nut chewing are the most common risk factors for oral cancer. Often individuals with pre cancer even notice the alterations, such as reduced mouth opening in oral submucous fibrosis (OSMF), but they are not aware about the causes and consequences of these changes. Awareness about causes and features of oral cancers can be very helpful in prevention, control and early diagnosis of oral cancer.Methods: A cross-sectional study was carried out among students from Mumbai University, India during May-June 2017. Five hundred students were approached to participate in the study of which 400 agreed to participate. Pretested questionnaire was distributed and collected data was analyzed using IBM SPSS version 23.Results: There were 199 (49%) males and 201 (50%) females in the study and response rate was (80%). Respondents had good knowledge about oral cancer. Seventy four percent (268/362) respondents correctly identified smoking, and tobacco chewing as possible causes of oral cancer. Almost all (96%; 348/362) respondents correctly responded that oral cancer does not spread from person to person through touch or speaking. Seventy two percent (260/362) respondents believed that oral cancer is curable. Significantly higher number of male (98%) compared to female participants answered correctly to questions regarding spread of disease and occurrence of oral cancer in AIDS patients.Conclusions: Participants showed good knowledge about oral cancer. Female participants showed lesser knowledge compared to male counterparts. Details about oral cancer should be incorporated in the undergraduate curriculum and periodic awareness programs should be organized for students.

scholarly journals Gambaran Kebiasaan Menyirih dan Lesi Mukosa Mulut pada Mahasiswa Papua Di Manado

e-GIGI ◽  
2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Dame R. Marbun
Keyword(s):  
Oral Submucous Fibrosis ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Driving Factor ◽  
Sectional Study ◽  
Cross Sectional ◽  
Slaked Lime ◽  
Oral Mucosal Lesions ◽  
Submucous Fibrosis ◽  
Mucosal Lesions

Kebiasaan menyirih telah dilakukan sejak dahulu kala di Indonesia, khususnya pada suku Papua. Banyak anggapan masyarakat bahwa menyirih dapat menguatkan gigi geligi dan menghambat terjadinya karies, namun dibalik dampak positif dari menyirih ini, ada juga dampak negatifnya berupa timbulnya lesi pada mukosa yang melapisi rongga mulut.Tujuan penelitian ini yaitu untuk memperoleh gambaran kebiasaan menyirih pada mahasiswa Papua di Kota Manado, mencakup: tujuan menyirih, bahan campuran menyirih, lamanya kebiasaan menyirih, frekuensi menyirih, dan faktor pendorong kebiasaan menyirih serta untuk mengetahui gambaran lesi mukosa mulut pada mahasiswa Papua di Kota Manado.Jenis penelitian ini yaitu penelitian desktiptif dengan pendekatan cross-sectional study. Teknik pengambilan sampel yang digunakan ialah total sampling dengan jumlah sampel 30 orang. Dari 30 subjek yang diperiksa, sebagian besar merupakan wanita, usia 17-27 tahun. Lamanya menyirih terbanyak 6-10 tahun, dengan frekuensi terbanyak 1-3 kali sehari, bahan campuran menyirih yang paling banyak digunakan ialah campuran sirih, pinang dan kapur. Faktor pendorong utama menyirih yakni karena keinginan sendiri, dimana tujuan menyirih terbanyak yakni agar gigi menjadi kuat dan sehat. Dari 30 subjek ada 29 orang (96,66%) memiliki lesi dalam rongga mulutnya. Lesi yang diduga sebagai Oral Submucous Fibrosis yakni sebanyak 90% dan lesi yang diduga sebagai Betel Chewers Mucosa sebanyak 6,66%.Kata kunci: Kebiasaan menyirih, lesi mukosa mulut, Oral Submucous Fibrosis, Betel Chewer’s MucosaABSTRACTBetel chewing as a habit has been done since a long time ago in Indonesia, especially in Papua. There are some public perceptions that betel chewing can strengthen teeth and prevent caries. But, behind the positive effect of betel chewing, there are negative effects too, such as the onset of lesions in the oral mucosa.The purpose of this research is to get an overview of betel chewing habit on Papuan students in Manado, including the purpose of betel chewing, the complete material of betel chewing, duration of betel chewing, frequency of betel chewing, the driving factor of betel chewing, and to get an overview on oral mucosal lesions on Papuan students in Manado.The type of this research is descriptive research with a cross - sectional study. The sampling technique is total sampling with a sample size of 30 people. The 30 examined subjects, mostly women with age ranging from 17-27 years. The most length of chewing from 6-10 years, with the highest frequency of chewing 1-3 times a day, the average mixture of betel commonly used is betel, areca nut and slaked lime. The major driving factor in betel chewing is their own desire and the most common purpose is to get a strong and healthy teeth. 29 of 30 subjects (96,66%) have lesions in the oral cavity. In 90% of the sample, expected as Oral Submucous Fibrosis and in 6,66% expected as Betel Chewer’s Mucosa.Keyword: Betel chewing habit, oral mucosal lesions, Oral Submucous Fibrosis, Betel Chewer’s Mucosa

scholarly journals Maxillofacial injuries among Brazilian children and adolescents victims of traffic accidents

2015 ◽  
Vol 63 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Laís Gonzaga de FARIAS ◽  
Rebeca Valeska Soares PEREIRA ◽  
Lorenna Mendes Temóteo BRANDT ◽  
Thaliny Batista Sarmento de OLIVEIRA ◽  
Alidianne Fábia Cabral XAVIER ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Children And Adolescents ◽  
Traffic Accidents ◽  
Young Male ◽  
Cross Sectional Study ◽  
Body Region ◽  
Maxillofacial Injuries ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

OBJECTIVE: To analyze the prevalence of morbidity due to traffic accidents in children and adolescents and its relationship with maxillofacial injuries in the city of Campina Grande, Paraíba, Brazil. METHODS: This cross-sectional study analyzed 533 forensic reports of individuals aged 0-19 years, victims of external causes in Campina Grande, Brazil, in 2013. Data were collected through a form containing variables sex, age, day of week, time, type of traffic accident, injured body region, presence of fractures, maxillofacial and oral cavity injuries. The Statistical Package for Social Sciences software (SPSS) was used for data analysis. Prevalence ratios and confidence intervals at 95% were estimated with the chi-square test. RESULTS: There was predominance of males (75.0%) aged 15-19 years (65.0%), with association between sex and occurrence of traffic accidents (p <0.001). The afternoon shift recorded 36.7% of cases of accidents involving motorcyclists (55.0%). In 25.0% of cases, there were injuries on the head and 26.7% on the face. Head and face injuries were observed in 10.0% of patients, while maxillofacial and oral cavity injuries were present in 21.7% and 6.7%, respectively. There was an association between occurrence of accident and face injuries (p = 0.009). CONCLUSION: Traffic accidents affect mostly young male individuals, causing multiple injuries in different body areas, including maxillofacial and oral cavity injuries.

scholarly journals Habit-associated salivary pH changes in oral submucous fibrosis-A controlled cross-sectional study

2015 ◽  
Vol 19 (2) ◽  
pp. 175 ◽  
Author(s):  
Mandana Donoghue ◽  
PraveenS Basandi ◽  
H Adarsh ◽  
GS Madhushankari ◽  
M Selvamani ◽  
...  
Keyword(s):  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Ph Changes ◽  
Salivary Ph ◽  
Submucous Fibrosis

scholarly journals High prevalent human papillomavirus infections of the oral cavity of asymptomatic HIV-positive men

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Rocío Méndez-Martínez ◽  
Silvia Maldonado-Frías ◽  
Salvador Vázquez-Vega ◽  
Yanink Caro-Vega ◽  
José Guadalupe Rendón-Maldonado ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Oral Cavity ◽  
Anal Canal ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Oral Infections ◽  
Immunodeficiency Virus ◽  
High Prevalence ◽  
Sex With Men ◽  
High Risk Hpv

Abstract Background Incidence of anal and oral infections with Human Papillomavirus (HPV) is increasing, particularly among Human Immunodeficiency Virus-positive (HIV+) men. HPV type 16 has exhibited the highest incidence and only limited data is available on other prevalent types, variants of HPV16, as well as associated factors. We were interested in identifying prevalent HPV types, variants of type 16, as well as factors associated with HPV16 infections in the oral cavity of HIV+ men who have sex with men (MSM). Methods A cross-sectional study of oral cavity samples from HIV+ MSM, that in a previous study were identified as positive for HPV16 in the anal canal. Cells from the oral cavity (102 samples, paired with 102 from the anal canal of same patient) were used to extract DNA and detect HPV infections using INNO-LiPA HPV Genotyping Extra II, and PCR. From these, 80 samples (paired, 40 anal and 40 oral) were used to identify variants of type 16 by sequencing. Statistical differences were estimated by the X2 test, and p values equal to or less than 0.05 were considered significant. SPSS ver. Twenty-four statistical software (IBM Corp) was used. Results We found a high prevalence of High-Risk HPV (HR-HPV) and Low-Risk HPV (LR-HPV). Patients were positive in the oral cavity for HR types; 16, 39 and 18 (80.4, 61.8 and 52.9% respectively) and LR types 11 and 6 (53.9 and 34.3% respectively). Surprisingly, only European variants of type 16 were found in the oral cavity, although American Asian (22.5%) and African (2.5%) variants were identified in the anal canal. The analysis showed that CD4 counts could be the most important risk factor associated with HR-HPV infections in the oral cavity, anal canal or both anatomical regions. The risk of infection of the oral cavity with type 18 increased in men diagnosed with HIV for more than 6 years. Conclusions Prevalence of both HR and LR HPV’s in the oral cavity of Mexican HIV+ MSM is very high. The fact that only European variants of HPV16 were found in the oral cavity suggest a possible tropism not previously described.

scholarly journals Histopathology of Cutaneous Leishmaniasis Caused by Leishmania donovani in Sri Lanka

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Harshima Wijesinghe ◽  
Nayana Gunathilaka ◽  
Saveen Semege ◽  
Nishantha Pathirana ◽  
Nuwani Manamperi ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Cutaneous Leishmaniasis ◽  
Leishmania Donovani ◽  
Clinical Presentation ◽  
Cross Sectional Study ◽  
Causative Organism ◽  
Variable Intensity ◽  
Cross Sectional ◽  
The North ◽  
Parasitic Load

Cutaneous leishmaniasis (CL) is a neglected tropical disease that is gaining importance in Sri Lanka and internationally. The clinical presentation, pathology, and method of parasite elimination in CL vary according to the species. Leishmania donovani is the causative organism for leishmaniasis in Sri Lanka. This collaborative cross-sectional study describes the clinicopathological features of cutaneous leishmaniasis among personnel of the tri-forces serving in the North and East of the country. The histology of fifty cases of CL confirmed by at least two methods (slit skin smear, lesion aspirate, tissue impression, and histology) was reviewed. The parasitic load was assessed semiquantitatively. The histological features were correlated with the clinical presentation and organism load. The majority (89.8%; n=44) presented with a single lesion mostly located in the upper limb (69.4%). The lesion types included papule (34.7%), nodule (32.7%), and an ulcer (30.6%). The evolution time of lesions averaged 31.55 weeks. Epidermal changes were observed in 49 of the biopsies and included hyperkeratosis (90.0%; n=45), acanthosis (44.0%; n=22), atrophy (34.0%; n=17), and interface change (66%; n=33). Dermal changes were seen in all cases and were characterized by a lymphohistioplasmacytic inflammatory infiltrate of variable intensity with ill-formed granuloma in 19 cases (38%) and well-formed epithelioid granulomas in 22 cases (44%). Focal necrosis was present in 20% (n=10). Leishmania amastigote forms were observed in 88% (n=44). Transepidermal elimination (P=0.025), granuloma (P=0.027) formation, and type of lesion (P=0.034) were significantly associated with the organism load. Granuloma formation was associated with a reduction in organism load, indicating that the macrophage activation played an important role in the control of the organism.

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