scholarly journals The Prevalence of Malignant Tumors of the Eye and Adnexa (C69)

2020 ◽  
Vol 17 (3) ◽  
pp. 495-501
Author(s):  
V. M. Merabishvili ◽  
E. N. Merabishvili

Malignant tumors of the eye and its adnexa (C69) relates to rare tumors. Until 2011, this group of tumors was not included to the official cancer report in Russia.Purpose: to investigate the incidence of malignant tumors of eye and its adnexa (C69) in the population of St. Petersburg, to consider the dynamics of a complex of analytical indicators. Standard methods of statistical analysis, state reporting materials and data from the St. Petersburg Population Cancer Register were used. Malignant tumors of the eye and its adnexa (С69) were started to be officially registered only from 2011 onwards, however not in full as only Form 7 that allows to calculate morbidity was filled in. Other information could be obtained from the databases of the Population Cancer Registers (PRR), organized in the country in the late 90’s. Each year, more than 1,000 thousand (e.g.1977–2017 year) cases of malignant tumors of eye and its adnexa (С69) are detected in the whole country. In 2011, 925 cases were diagnosed. In Russia, the crude rate of malignant tumors of the eye and its adnexa (С69) has increased from 2011 to 2017 years from 0.65/100,000 in 2011 to 0.73/100,000 in 2017, respectively, +12.3 % (both sexes), standardized, eliminating the difference in the age composition of the population, remained almost unchanged –0.54 0/0000 and 0.53 0/0000. The standardized incidence rate in men of malignant tumors of eye and its adnexa (С69) in 2017 was 0.58 0/0000, women –0.49 0/0000. The state reporting for malignant tumors of eye and its adnexa (С69) does not provide for the distribution of these patients by age, stage and other parameters. State mortality statistics do not provide for the review of the C-69 heading ICD-10. All of this led us to conduct in-depth analysis of the dynamics of morbidity and mortality of eye cancer on the basis of the PRR database of SaintPetersburg. An insignificant increase in the incidence rate of the Russian population of the eye cancer, completely associated with the aging of the population, has been established. Positive increase in the observed and relative survival of patients has been also revealed. 

2019 ◽  
Vol 65 (2) ◽  
pp. 205-219 ◽  
Author(s):  
V. Merabishvili

The mortality rate is one of the most important criteria for assessing the health of the population. However, it is important to use analytical indicators correctly, especially when evaluating time series. The value of the “gross” mortality is closely linked with a specific weight of persons of elderly and senile ages. All international publications (WHO, IARC, territorial cancer registers) assess the dynamics of morbidity and mortality only by standardized indicators that eliminate the difference in the age composition of the compared population groups. In Russia, from 1960 to 2017, the share of people of retirement age has increased more than 2 times. The structure of mortality from malignant tumors has changed dramatically. The paper presents the dynamics of gross and standardized mortality rates from malignant tumors in Russia and in all administrative territories. Shows the real success of the Oncology service. The medium-term interval forecast until 2025 has been calculated.


2021 ◽  
Author(s):  
Chao Yu ◽  
Qiang Yan ◽  
De-Guan Li ◽  
Yi-Gao Wang ◽  
Xiao-Dong Yang ◽  
...  

Abstract Background: Uncut Roux en-Y gastrojejunostomy, recently developed in China is useful in the treatment of distal gastric cancer. This study aims to compare laparoscopic gastric jejunum Uncut Roux-en-Y anastomosis with conventional anastomosis in the surgical treatment of distal gastric malignancy.Methods: A total of 178 cases diagnosed with distal gastric malignant tumors were surgically treated in the First affiliated Hospital of Anhui University of cavity mirrors. In this retrospective study, the clinical data of patients and their follow-up records were analyzed. Out of the 178 cases, 112 cases (uncut group) were the observation group for stomach jejunum Uncut Roux-en-Y anastomosis, the control group for the stomach, 66 cases (conventional group) were for jejunum Roux-en-Y anastomosis and Billroth Ⅰ and Billroth Ⅱ anastomosis. A comparison between the two groups was conducted based on the general situation of the patients, TNM stage, and one-year survival rate. A P-value of less than 0.05 was considered statistically significant (p<0.05), while a P-value of more than 0.05 was considered statistically insignificant (p>0.05).Results: There was no significant difference was reported between the two groups in terms of the general situation and TNM stage. A comparison on postoperative complications between the two groups revealed that the incidence rate of postoperative anastomotic bleeding was 0.9% (1/112), 6.1% (4/66), the incidence rate of alkaline reflux gastritis was 1.8% (2/112), 9.1% (6/66), the incidence rate of anastomotic fistula was 0.0% (0/112), 3.0% (3/66), and the Roux retention syndrome (RSS) incidence rate was 0.9% (1/112), 7.6% (5/66). The observation group significantly lower than the control group, and the difference was statistically significant. The incidence rate of overall complications was at 3.6% (4/112) and 25.8% (17/66), which was significantly lower in the observation group than in the control group, and the difference was statistically significant. Notably, there was no significant difference in 1-year survival rate between the two groups.Conclusion: Laparoscopic gastric jejunal Uncut Roux-en-Y anastomosis significantly reduces the risk of postoperative complications of the digestive tract. Its operation is easy and exhibits an effective curative effect. Moreover, it has a better surgical effect and a promising clinical application prospect compared to conventional gastric jejunal anastomosis.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Andrés Moreno Roca ◽  
Luciana Armijos Acurio ◽  
Ruth Jimbo Sotomayor ◽  
Carlos Céspedes Rivadeneira ◽  
Carlos Rosero Reyes ◽  
...  

Abstract Objectives Pancreatic cancers in most patients in Ecuador are diagnosed at an advanced stage of the disease, which is associated with lower survival. To determine the characteristics and global survival of pancreatic cancer patients in a social security hospital in Ecuador between 2007 and 2017. Methods A retrospective cohort study and a survival analysis were performed using all the available data in the electronic clinical records of patients with a diagnosis of pancreatic cancer in a Hospital of Specialties of Quito-Ecuador between 2007 and 2017. The included patients were those coded according to the ICD 10 between C25.0 and C25.9. Our univariate analysis calculated frequencies, measures of central tendency and dispersion. Through the Kaplan-Meier method we estimated the median time of survival and analyzed the difference in survival time among the different categories of our included variables. These differences were shown through the log rank test. Results A total of 357 patients diagnosed with pancreatic cancer between 2007 and 2017 were included in the study. More than two-thirds (69.9%) of the patients were diagnosed in late stages of the disease. The median survival time for all patients was of 4 months (P25: 2, P75: 8). Conclusions The statistically significant difference of survival time between types of treatment is the most relevant finding in this study, when comparing to all other types of treatments.


Author(s):  
В. М. Мерабишвили ◽  
Д. М. Дубовиченко ◽  
М. Ю. Вальков ◽  
А. М. Щербаков ◽  
Э. Н. Мерабишвили

Рак прямой кишки (РПК) - это злокачественная опухоль дистального отдела толстой кишки эпителиального происхождения. Ежегодно в России регистрируется более 30 тыс. (30 969 в 2018 г.) новых случаев РПК и 16 тыс. (16 151) случаев смерти. Индекс достоверности учета (отношение числа умерших к заболевшим) составляет 0,52 %. РПК относится к локализациям со средним уровнем летальности. В Северо-Западном Федеральном округе зарегистрировано более 3 тыс. первичных случаев РПК (3 285 в 2018 г.). Государственная статистика РПК представляет данные о заболеваемости и смертности населения по трем рубрикам МКБ-10 вместе (С19-21). Детальная разработка данных не только отдельно по каждой рубрике МКБ-10, но и по четвертому знаку возможна только по материалам баз данных раковых регистров. Созданный нами Популяционный раковый регистр Северо-Западного Федерального округа насчитывал на 01.01.2019 г. более 1 млн (1 067 661) случаев злокачественных новообразований (ЗНО), в том числе РПК - 50 745 случаев, или 4,8 %. Удельный вес РПК близок к среднероссийскому - 4,9 %. В работе представлена детальная структура онкологической патологии по РПК. Ведущая роль из трех указанных рубрик принадлежит ЗНО прямой кишки (С20) - 75,4 %; 19,8 % приходится на ЗНО ректосигмоидного отдела (С19) и только 4,7 % на С21 - ЗНО ануса и анального канала. По всем этим рубрикам представлена динамика структуры, которая оказалась достаточно устойчивой. Rectal cancer is a malignant tumor of the distal colon of epithelial origin. Every year, more than 30,000 (30 969 - 2018) new cases of Rectal cancer and 16,000 deaths (16 151) are registered in Russia. The index of reliability of accounting (the ratio of the number of dead to sick) is 0,52 %. Rectal cancer refers to localities with an average mortality rate. In the North-Western Federal district, more than 3 thousand primary cases of Rectal cancer were registered (3285 - 2018). The state statistics of the Rectal cancer provides data on morbidity and mortality in three categories of ICD-10 together (C19-21). Detailed development of data not only separately for each category of ICD-10, but also for the fourth sign is possible only from the data bases of cancer registers. As of 01.01.2019, the Population cancer register of the North-Western Federal district created by us totaled more than 1 million cases of malignant tumors (1 067 661), including Rectal cancer - 50 745 cases, or 4,8 %. The share of the Rectal cancer is close to the national average - 4,9 %. The article presents a detailed structure of cancer pathology in Rectal cancer. The leading role of the 3 specified categories belongs to the rectal malignant tumors (C20) - 75,4 %, 19,8 % falls on the malignant tumors of the rectosigmoid department (C19) and only 4,7 % on the C21 - malignant tumors of the anus and anal canal. For all these categories, the dynamics of the structure is presented, which proved to be quite stable.


Author(s):  
В. М. Мерабишвили ◽  
В. К. Гуркало ◽  
Э. Н. Мерабишвили

Рак печени (РП) - тяжелейшая онкопатология. В России смертность превышает число первично-учтенных больных в среднем. Ежегодно в России регистрируют более 8 тыс. (8 810 - в 2018 г.) случаев рака печени и более 10 тыс. (10 018 - в 2018 г.) случаев смерти от этой причины. Использованы стандартные методы медицинской статистики, все зарегистрированные первичные случаи РП в России. Углубленная разработка материала проведена на основе базы данных Популяционного ракового регистра Северо-Западного Федерального округа РФ. Проанализированы данные всего комплекса доступной информации в целом по России. Установлен прирост заболеваемости РП населения России за 18 лет в «грубых» показателях и абсолютных числах на 20% и в стандартизованных - на 1,22%. У женщин отмечено снижение учтенных случаев РП на 4,55%. Смертность населения России в стандартизованных показателях снизилась за 18 лет практически на 3%. Превышение числа умерших над заболевшими от РП существенно возрастает в старших возрастных группах. Индекс достоверности учета (ИДУ) - это отношение абсолютных чисел или «грубых» показателей смертности населения к заболеваемости. Для всех злокачественных новообразований (ЗНО) величина в среднем по России составила 0,47, практически совпадающая со среднеевропейской. ИДУ у мужчин - 0,55, выше расчетных показателей для женщин - 0,40, что в первую очередь связано с более благоприятной структурой заболеваемости женщин ЗНО. Медиана выживаемости первичных больных РП составляет немногим более 3 мес. Пятилетняя выживаемость больных РП даже на ранних стадиях составляет у лиц моложе 60 лет с I стадией - 25,3%, старше 60 лет - только 17,2%, со II стадией - 17,9 и 11% соответственно. Liver cancer is a severe oncopathology. Mortality exceeds the number of primary-accounted patients in Russia on average. Every year in Russia more than eight thousand (8 810 in 2018) cases of liver cancer and more than 10 000 (10 018 in 2018) deaths from this cause are registered. Used Standard methods of medical statistics, all registered primary cases of liver cancer in Russia. In-depth development of the material was carried out on the basis of the database of the Population cancer register of the North-Western Federal district of the Russian Federation. The analysis of the data of the whole complex of available information in Russia as a whole is carried out. In-depth data development was carried out on the basis of the database of the Population cancer register of the North-Western Federal district of the Russian Federation. The increase in the incidence of liver cancer in Russia over 18 years in «rough» indicators and absolute numbers by 20 % and in standardized by 1,22 % was established. In women, there was a decrease in reported cases of liver cancer by 4,55 %. The mortality rate of the Russian population in standardized indicators has decreased by almost 3 % over 18 years. The excess of the number of deaths over those from liver cancer increases significantly in older age groups. The index of reliability of accounting is the ratio of absolute numbers or «rough» indicators of mortality to morbidity. For all malignant tumors, its value on average in Russia was 0,47, almost coinciding with the average European. The index of reliability of accounting for men is 0,55, higher than the calculated indicators for women - 0,40, which is primarily due to a more favorable structure of the incidence of malignant tumors in women. The median survival of primary liver cancer patients is a little more than three months. The fi ve-year survival rate of patients with liver cancer even in the early stages is in the first among persons younger than 60 years - 25,3 %, over 60 years - only 17,2 %, in the second, respectively, 17,9 and 11%.


1993 ◽  
Vol 162 (4) ◽  
pp. 463-466 ◽  
Author(s):  
Julian Stern ◽  
Michael Murphy ◽  
Christopher Bass

A postal questionnaire was sent to 195 senior British psychiatrists who were asked about their attitudes towards the DSM-III-R diagnosis of somatisation disorder (SD) and the ICD-10 diagnosis of multiple somatisation disorder. Of the 148 respondents, 98 (66%) had experience of liaison psychiatry, and these psychiatrists used the diagnosis significantly more often than those without liaison sessions. More than half the respondents perceived SD as both a personality disorder and a mental state disorder, although 27% thought that patients with SD had an undiagnosed physical disease. The marked discrepancy between British and North American psychiatrists in diagnostic practices was perceived to be a consequence of both the difference in health care systems and the interest shown in the disorder by North American psychiatrists, rather than a reflection of genuine differences in prevalence.


Author(s):  
A. V. Kudryavtseva ◽  
S. S. Bagnenko ◽  
I. I. Dzidzawa ◽  
I. S. Zheleznyak ◽  
G. E. Trufanov ◽  
...  

Aim. To evaluate the capabilities of CT and MRI in the assessment of resectable and potentially resectable pancreatic tumors.Materials and methods. From 2015 to 2020 CT and MRI examination of the abdomen was performed in 220 patients with pancreatic ductal adenocarcinoma. The average age of the patients was 54.6 ± 9.9 years. 198 (90%) patients had a tumor of the pancreas head, 22 (10%) patients had a tumor of the body or tail of the organ. 110 (50%) people were recognized as inoperable. The results of examination of 88 (40%) patients were subjected to in-depth analysis.Results. Eighty eight patients were assessed for tumor resectability. In 36 (40.9%) cases, the neoplasm was recognized as resectable, and the standard resection was performed. In 52 (59.1%) cases, the tumor was determined as borderline resectable; extended gastropancreatoduodenal resection was performed.The usefulness of CT was shown in assessing the features of the variable vascular anatomy of the hepatopancreatobiliary area, determining the nature of the involvement of key vessels in the pathological process and lesions of the pancreas as a whole. The importance of using multiphase CT scanning is demonstrated and emphasized. The advantages of the MRI are indicated, including examples of the effective use of diffusion-weighted images.Conclusion. Multiphase MDCT and MRI with dynamic contrast enhancement are the leading methods of radiological diagnosis of malignant tumors of the pancreas and effectively complement each other.


2019 ◽  
Vol 6 (2) ◽  
pp. 76-78
Author(s):  
Pardis Soltanpoor ◽  
Faranak Behnaz ◽  
Hamidreza Azizi Faresani ◽  
Afsoun Seddighi ◽  
Maede Karimian

Chordomas rare low grade slow-growing malignant tumors with an incidence rate of 1 in 100000 individuals.32% of chordomas occur in the clivus. Diagnosing Clival chordomas could be challenging due to their rare prevalence, insidious onset, and tendency to involve anywhere throughout the craniospinal column. Treating these tumors can also present as a challenge due to their proximity to vital structures and high recurrence rate. We present a case of massive recurrent Clival chordoma in a 27-year-old patient and discuss the anesthetic considerations in such cases.


Author(s):  
Mehul S. Raval

The chapter presents an application of reversible data hiding for the authentication of image travelling over a hostile and insecure communication channel. The reversible data resides in the image and tracks any changes done to it on a communication channel. The extraction of data and any modification to its structure reveals changes in the image. This allows the use of data hiding for forensic purpose. The reversible data hiding provides an additional advantage along with active forensics. The image regains original form after removal of the embedded data. However, reversible data hiding is an interplay between the image quality and watermarking capacity. The chapter presents the generic framework for data hiding and discusses its special case reversible data hiding. It presents capacity-behavior analysis of the difference expansion scheme. It performs in-depth analysis on the type of predictor and its impact on the capacity of the reversible data hiding scheme. Finally, the chapter presents a case study to showcase the use of reversible data hiding for image authentication.


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