Episodic memory recognition of the hippocampus using a deep learning method

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Takashi Kuremoto
Keyword(s):  
Deep Learning ◽  
Episodic Memory ◽  
Male Rat ◽  
Support Vector ◽  
Female Rat ◽  
Ca1 Neurons ◽  
Episodic Memories ◽  
Deep Learning Model ◽  
The Brain ◽  
Planning Action

Hippocampus plays an important role in processing episodic memory. The different patterns of multi-unit activity (MUA) of CA1 neurons in hippocampus corresponds to the different high order functions of the brain such as memory, association, planning, action decision, etc. In this paper, a deep learning model, which is a composition of convolutional neural network (CNN) and support vector machine (SVM), is adopted to classify 4 kinds of episodic memories of a male rat: restraint stress (restraint), contact with a female rat (female), contact with a male rat (male), and contact with a novel object (object). In addition, the characteristic patterns of the different events occurred in CA1 neurons are specified by the feature explanation of CNN using Grad-CAM. As the result, this study suggests that it is available to recognize episodic memories by MUA signals and vice versa.

scholarly journals PlncRNA-HDeep: plant long noncoding RNA prediction using hybrid deep learning based on two encoding styles

2021 ◽  
Vol 22 (S3) ◽  
Author(s):  
Jun Meng ◽  
Qiang Kang ◽  
Zheng Chang ◽  
Yushi Luan
Keyword(s):  
Deep Learning ◽  
Noncoding Rna ◽  
Nearest Neighbor ◽  
Short Term Memory ◽  
Biological Activities ◽  
Support Vector ◽  
Multiple Perspectives ◽  
K Nearest Neighbor ◽  
Rna Sequences ◽  
Deep Learning Model

Abstract Background Long noncoding RNAs (lncRNAs) play an important role in regulating biological activities and their prediction is significant for exploring biological processes. Long short-term memory (LSTM) and convolutional neural network (CNN) can automatically extract and learn the abstract information from the encoded RNA sequences to avoid complex feature engineering. An ensemble model learns the information from multiple perspectives and shows better performance than a single model. It is feasible and interesting that the RNA sequence is considered as sentence and image to train LSTM and CNN respectively, and then the trained models are hybridized to predict lncRNAs. Up to present, there are various predictors for lncRNAs, but few of them are proposed for plant. A reliable and powerful predictor for plant lncRNAs is necessary. Results To boost the performance of predicting lncRNAs, this paper proposes a hybrid deep learning model based on two encoding styles (PlncRNA-HDeep), which does not require prior knowledge and only uses RNA sequences to train the models for predicting plant lncRNAs. It not only learns the diversified information from RNA sequences encoded by p-nucleotide and one-hot encodings, but also takes advantages of lncRNA-LSTM proposed in our previous study and CNN. The parameters are adjusted and three hybrid strategies are tested to maximize its performance. Experiment results show that PlncRNA-HDeep is more effective than lncRNA-LSTM and CNN and obtains 97.9% sensitivity, 95.1% precision, 96.5% accuracy and 96.5% F1 score on Zea mays dataset which are better than those of several shallow machine learning methods (support vector machine, random forest, k-nearest neighbor, decision tree, naive Bayes and logistic regression) and some existing tools (CNCI, PLEK, CPC2, LncADeep and lncRNAnet). Conclusions PlncRNA-HDeep is feasible and obtains the credible predictive results. It may also provide valuable references for other related research.

scholarly journals A Hybrid Prognostics Deep Learning Model for Remaining Useful Life Prediction

Electronics ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 39
Author(s):  
Zhiyuan Xie ◽  
Shichang Du ◽  
Jun Lv ◽  
Yafei Deng ◽  
Shiyao Jia
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Learning Model ◽  
Recurrent Network ◽  
Remaining Useful Life ◽  
Support Vector ◽  
Second Phase ◽  
Learning Methods ◽  
Useful Life ◽  
Deep Learning Model

Remaining Useful Life (RUL) prediction is significant in indicating the health status of the sophisticated equipment, and it requires historical data because of its complexity. The number and complexity of such environmental parameters as vibration and temperature can cause non-linear states of data, making prediction tremendously difficult. Conventional machine learning models such as support vector machine (SVM), random forest, and back propagation neural network (BPNN), however, have limited capacity to predict accurately. In this paper, a two-phase deep-learning-model attention-convolutional forget-gate recurrent network (AM-ConvFGRNET) for RUL prediction is proposed. The first phase, forget-gate convolutional recurrent network (ConvFGRNET) is proposed based on a one-dimensional analog long short-term memory (LSTM), which removes all the gates except the forget gate and uses chrono-initialized biases. The second phase is the attention mechanism, which ensures the model to extract more specific features for generating an output, compensating the drawbacks of the FGRNET that it is a black box model and improving the interpretability. The performance and effectiveness of AM-ConvFGRNET for RUL prediction is validated by comparing it with other machine learning methods and deep learning methods on the Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) dataset and a dataset of ball screw experiment.

scholarly journals Precision Measurement for Industry 4.0 Standards towards Solid Waste Classification through Enhanced Imaging Sensors and Deep Learning Model

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Leow Wei Qin ◽  
Muneer Ahmad ◽  
Ihsan Ali ◽  
Rafia Mumtaz ◽  
Syed Mohammad Hassan Zaidi ◽  
...  
Keyword(s):  
Deep Learning ◽  
Solid Waste ◽  
Precision Measurement ◽  
Mobile Applications ◽  
Industry 4.0 ◽  
Learning Model ◽  
Edge Computing ◽  
Support Vector ◽  
Waste Classification ◽  
Deep Learning Model

Achievement of precision measurement is highly desired in a current industrial revolution where a significant increase in living standards increased municipal solid waste. The current industry 4.0 standards require accurate and efficient edge computing sensors towards solid waste classification. Thus, if waste is not managed properly, it would bring about an adverse impact on health, the economy, and the global environment. All stakeholders need to realize their roles and responsibilities for solid waste generation and recycling. To ensure recycling can be successful, the waste should be correctly and efficiently separated. The performance of edge computing devices is directly proportional to computational complexity in the context of nonorganic waste classification. Existing research on waste classification was done using CNN architecture, e.g., AlexNet, which contains about 62,378,344 parameters, and over 729 million floating operations (FLOPs) are required to classify a single image. As a result, it is too heavy and not suitable for computing applications that require inexpensive computational complexities. This research proposes an enhanced lightweight deep learning model for solid waste classification developed using MobileNetV2, efficient for lightweight applications including edge computing devices and other mobile applications. The proposed model outperforms the existing similar models achieving an accuracy of 82.48% and 83.46% with Softmax and support vector machine (SVM) classifiers, respectively. Although MobileNetV2 may provide a lower accuracy if compared to CNN architecture which is larger and heavier, the accuracy is still comparable, and it is more practical for edge computing devices and mobile applications.

scholarly journals The Diagnosis of Alzheimer’s Disease: An Ensemble Approach

2020 ◽  
Author(s):  
Jingyan Qiu ◽  
Linjian Li ◽  
Yida Liu ◽  
Yingjun Ou ◽  
Yubei Lin
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Deep Learning ◽  
Large Scale ◽  
Early Stage ◽  
Training Transfer ◽  
Detection And Diagnosis ◽  
Magnetic Resonance Imaging Mri ◽  
Deep Learning Model ◽  
The Brain

Alzheimer’s disease (AD) is one of the most common forms of dementia. The early stage of the disease is defined as Mild Cognitive Impairment (MCI). Recent research results have shown the prospect of combining Magnetic Resonance Imaging (MRI) scanning of the brain and deep learning to diagnose AD. However, the CNN deep learning model requires a large scale of samples for training. Transfer learning is the key to enable a model with high accuracy by using limited data for training. In this paper, DenseNet and Inception V4, which were pre-trained on the ImageNet dataset to obtain initialization values of weights, are, respectively, used for the graphic classification task. The ensemble method is employed to enhance the effectiveness and efficiency of the classification models and the result of different models are eventually processed through probability-based fusion. Our experiments were completely conducted on the Alzheimer’s Disease Neuroimaging Initiative (ADNI) public dataset. Only the ternary classification is made due to a higher demand for medical detection and diagnosis. The accuracies of AD/MCI/Normal Control (NC) of different models are estimated in this paper. The results of the experiments showed that the accuracies of the method achieved a maximum of 92.65%, which is a remarkable outcome compared with the accuracies of the state-of-the-art methods.

scholarly journals Improved Deep Feature Learning by Synchronization Measurements for Multi-Channel EEG Emotion Recognition

Complexity ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-15 ◽  
Author(s):  
Hao Chao ◽  
Liang Dong ◽  
Yongli Liu ◽  
Baoyun Lu
Keyword(s):  
Deep Learning ◽  
Emotion Recognition ◽  
Affective Computing ◽  
Learning Model ◽  
Support Vector ◽  
Eeg Signals ◽  
Global Synchronization ◽  
Spatial Characteristics ◽  
Maximal Information Coefficient ◽  
Deep Learning Model

Emotion recognition based on multichannel electroencephalogram (EEG) signals is a key research area in the field of affective computing. Traditional methods extract EEG features from each channel based on extensive domain knowledge and ignore the spatial characteristics and global synchronization information across all channels. This paper proposes a global feature extraction method that encapsulates the multichannel EEG signals into gray images. The maximal information coefficient (MIC) for all channels was first measured. Subsequently, an MIC matrix was constructed according to the electrode arrangement rules and represented by an MIC gray image. Finally, a deep learning model designed with two principal component analysis convolutional layers and a nonlinear transformation operation extracted the spatial characteristics and global interchannel synchronization features from the constructed feature images, which were then input to support vector machines to perform the emotion recognition tasks. Experiments were conducted on the benchmark dataset for emotion analysis using EEG, physiological, and video signals. The experimental results demonstrated that the global synchronization features and spatial characteristics are beneficial for recognizing emotions and the proposed deep learning model effectively mines and utilizes the two salient features.

A Study on Brain Tumor Detection and Segmentation Using Deep Learning Techniques

2020 ◽  
Vol 17 (4) ◽  
pp. 1925-1930
Author(s):  
Ambeshwar Kumar ◽  
R. Manikandan ◽  
Robbi Rahim
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Deep Learning ◽  
Brain Tumor ◽  
Tumor Detection ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Learning Techniques ◽  
Convolution Algorithm ◽  
The Brain

It’s a new era technology in the field of medical engineering giving awareness about the various healthcare features. Deep learning is a part of machine learning, it is capable of handling high dimensional data and is efficient in concentrating on the right features. Tumor is an unbelievably complex disease: a multifaceted cell has more than hundred billion cells; each cell acquires mutation exclusively. Detection of tumor particles in experiment is easily done by MRI or CT. Brain tumors can also be detected by MRI, however, deep learning techniques give a better approach to segment the brain tumor images. Deep Learning models are imprecisely encouraged by information handling and communication designs in biological nervous system. Classification plays an significant role in brain tumor detection. Neural network is creating a well-organized rule for classification. To accomplish medical image data, neural network is trained to use the Convolution algorithm. Multilayer perceptron is intended for identification of a image. In this study article, the brain images are categorized into two types: normal and abnormal. This article emphasize the importance of classification and feature selection approach for predicting the brain tumor. This classification is done by machine learning techniques like Artificial Neural Networks, Support Vector Machine and Deep Neural Network. It could be noted that more than one technique can be applied for the segmentation of tumor. The several samples of brain tumor images are classified using deep learning algorithms, convolution neural network and multi-layer perceptron.

scholarly journals The Impact of Emotional Music on Active ROI in Patients with Depression Based on Deep Learning: A Task-State fMRI Study

2019 ◽  
Vol 2019 ◽  
pp. 1-14
Author(s):  
Renzhou Gui ◽  
Tongjie Chen ◽  
Han Nie
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Correlation Matrix ◽  
Nearest Neighbor ◽  
Learning Model ◽  
Fmri Data ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
The Impact ◽  
Deep Learning Model

With the continuous development of science, more and more research results have proved that machine learning is capable of diagnosing and studying the major depressive disorder (MDD) in the brain. We propose a deep learning network with multibranch and local residual feedback, for four different types of functional magnetic resonance imaging (fMRI) data produced by depressed patients and control people under the condition of listening to positive- and negative-emotions music. We use the large convolution kernel of the same size as the correlation matrix to match the features and obtain the results of feature matching of 264 regions of interest (ROIs). Firstly, four-dimensional fMRI data are used to generate the two-dimensional correlation matrix of one person’s brain based on ROIs and then processed by the threshold value which is selected according to the characteristics of complex network and small-world network. After that, the deep learning model in this paper is compared with support vector machine (SVM), logistic regression (LR), k-nearest neighbor (kNN), a common deep neural network (DNN), and a deep convolutional neural network (CNN) for classification. Finally, we further calculate the matched ROIs from the intermediate results of our deep learning model which can help related fields further explore the pathogeny of depression patients.

scholarly journals SmartFall: A Smartwatch-Based Fall Detection System Using Deep Learning

Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3363 ◽  
Author(s):  
Taylor Mauldin ◽  
Marc Canby ◽  
Vangelis Metsis ◽  
Anne Ngu ◽  
Coralys Rivera
Keyword(s):  
Support Vector Machine ◽  
Deep Learning ◽  
Naive Bayes ◽  
Fall Detection ◽  
Learning Model ◽  
Naïve Bayes ◽  
Sensor Data ◽  
Support Vector ◽  
Accelerometer Data ◽  
Deep Learning Model

This paper presents SmartFall, an Android app that uses accelerometer data collected from a commodity-based smartwatch Internet of Things (IoT) device to detect falls. The smartwatch is paired with a smartphone that runs the SmartFall application, which performs the computation necessary for the prediction of falls in real time without incurring latency in communicating with a cloud server, while also preserving data privacy. We experimented with both traditional (Support Vector Machine and Naive Bayes) and non-traditional (Deep Learning) machine learning algorithms for the creation of fall detection models using three different fall datasets (Smartwatch, Notch, Farseeing). Our results show that a Deep Learning model for fall detection generally outperforms more traditional models across the three datasets. This is attributed to the Deep Learning model’s ability to automatically learn subtle features from the raw accelerometer data that are not available to Naive Bayes and Support Vector Machine, which are restricted to learning from a small set of extracted features manually specified. Furthermore, the Deep Learning model exhibits a better ability to generalize to new users when predicting falls, an important quality of any model that is to be successful in the real world. We also present a three-layer open IoT system architecture used in SmartFall, which can be easily adapted for the collection and analysis of other sensor data modalities (e.g., heart rate, skin temperature, walking patterns) that enables remote monitoring of a subject’s wellbeing.

scholarly journals A Deep Learning Model for Data-Driven Discovery of Functional Connectivity

Algorithms ◽  
2021 ◽  
Vol 14 (3) ◽  
pp. 75
Author(s):  
Usman Mahmood ◽  
Zening Fu ◽  
Vince D. Calhoun ◽  
Sergey Plis
Keyword(s):  
Deep Learning ◽  
Functional Connectivity ◽  
State Of The Art ◽  
Weighted Graph ◽  
Brain Regions ◽  
Classification Performance ◽  
Class Discrimination ◽  
Post Hoc ◽  
Deep Learning Model ◽  
The Brain

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of functional magnetic resonance imaging (fMRI) correlation matrix. However, most of the work with the FC depends on the way the connectivity is computed, and it further depends on the manual post-hoc analysis of the FC matrices. In this work, we propose a deep learning architecture BrainGNN that learns the connectivity structure as part of learning to classify subjects. It simultaneously applies a graphical neural network to this learned graph and learns to select a sparse subset of brain regions important to the prediction task. We demonstrate that the model’s state-of-the-art classification performance on a schizophrenia fMRI dataset and demonstrate how introspection leads to disorder relevant findings. The graphs that are learned by the model exhibit strong class discrimination and the sparse subset of relevant regions are consistent with the schizophrenia literature.

scholarly journals A Deep Learning-Based Approach for Detection of Dementia from Brain Mri

2021 ◽  
Vol 23 (07) ◽  
pp. 516-529
Author(s):  
Reshma L ◽  
◽  
Sai Priya Nalluri ◽  
Priya R Sankpal ◽  
◽  
...  
Keyword(s):  
Deep Learning ◽  
Brain Mri ◽  
Brain Magnetic Resonance Imaging ◽  
Support Vector ◽  
Imaging Data ◽  
Diagnosis Of Dementia ◽  
User Friendly ◽  
Clustering Pattern ◽  
Medical Analysis ◽  
The Brain

In this paper, a user-friendly system has been developed which will provide the result of medical analysis of digital images like magnetization resonance of image scan of the brain for detection and classification of dementia. The small structural differences in the brain can slowly and gradually become a major disease like dementia. The progression of dementia can be slowed when identified early. Hence, this paper aims at developing a robust system for classification and identifying dementia at the earliest. The method used in this paper for initial disclosure and diagnosis of dementia is deep learning since it can give important results in a shorter period of time. Deep Learning methods such as K-means clustering, Pattern Recognition, and Multi-class Support Vector Machine (SVM) have been used to classify different stages of dementia. The goal of this study is to provide a user interface for deep learning-based dementia classification using brain magnetic resonance imaging data. The results show that the created method has an accuracy of 96% and may be utilized to detect people who have dementia or are in the early stages of dementia.

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