scholarly journals Prevalence of iron deficiency anaemia among microcytic anaemic premenopausal patients at tertiary care hospital, Karachi

2020 ◽  
Vol 7 (12) ◽  
pp. 4720
Author(s):  
Ghulam Abbas Memon ◽  
Tooba Jawed Khan ◽  
Shabnam Abbas ◽  
Ghulam Abbas Shaikh ◽  
Nusrat Shah ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Reproductive Age ◽  
Outcome Variable ◽  
Care Hospital ◽  
Age Group ◽  
Microcytic Anaemia ◽  
Deficiency Anaemia ◽  
Civil Hospital ◽  
Increased Risk

Background: Iron deficiency anaemia (IDA) is the prevalent form of anaemia which has become a major public health problem, globally. Women in the reproductive age group (15–49 years of age) are at increased risk, especially in the South Asian population. It is of paramount importance to identify these micronutrient deficiencies in this age group as it adversely affects the birth outcomes, but the mother and the child at risk of morbidity and mortality during pregnancy.  Methods: A cross-sectional study was conducted at Civil Hospital, Karachi for 12 months i.e. October, 2018 to December, 2019. Data was prospectively collected from patients after obtaining written informed consent. 377 patients were included who met the diagnostic criteria. Descriptive statistics were used and qualitative data analysis; mean, standard deviation, frequency, and percentages were respectively calculated. Effect modifiers were controlled through stratification to see the effect of these on the outcome variable. For post-stratification, the chi-square test was applied with a p value of≤0.05.Results: A total of 377 patients with microcytic anaemia were enrolled from Civil Hospital, Karachi. Mean age, duration of anaemia, haemoglobin, height, weight and BMI in our study was 29.28±6.14 years, 1.41±0.26 months, 9.27±0.86 mg/dl, 26.72±1.56 kg/m2, 138±7.28 cm and 78.7±9.87 kg. Out of 377 patients with microcytic anaemia, 144 (38.2%) and 233 (61.8%) had and did not have iron deficiency anaemia.  Conclusions: IDA is frequently found in microcytic anaemia patients. Thus, it is important to screen premenopausal in female patients for iron deficiency presenting with microcytic anaemia to prevent adverse outcomes.  

scholarly journals Prevalence of Iron Deficiency Anaemia among the Reproductive Age Group Women Attending the Unani Hospital, Bangalore, Karnataka, India

2020 ◽  
Author(s):  
Mazharul Islam ◽  
Atiya Khan ◽  
Arish Mohammad Khan Sherwani
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anaemia ◽  
Economic Status ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Age Group ◽  
Cross Sectional ◽  
Deficiency Anaemia ◽  
Reproductive Age Group

Introduction: Iron Deficiency Anaemia (IDA) is the most widespread micronutrient deficiency. Globally, nearly two billion people are affected by anaemia. This disease most often affects children, women of child-bearing age, and pregnant women. Nearly half of the pregnant women in the world are estimated to be anaemic. Its prevalence varies according to region and socio-economic conditions. The majority of those who are anaemic live in developing countries where the problem is exacerbated by limited access to inadequate resources and appropriate treatment. Aim: To find out the prevalence of IDA in the reproductive age group women and its associated factors. Materials and Methods: This hospital based, cross-sectional study was conducted among 400 females, of age group 15-49 years. After obtaining the written informed consent, eligible subjects were inquired about socio-demographic variables, socio-economic status, anthropometric measurements and risk factors. Required investigations were done. All the information was recorded on the semi-structured schedule form. Chi-square/Fisher’s-exact test was used to find the significance of study parameters on categorical scale between two or more groups. Results: Prevalence of IDA was found to be 42% (168/400). Prevalence of IDA was significant with habitat (p=0.0180), exercise (p=0.0004), amount of blood loss during menstruation (p<0.0001), duration of flow during menstruation, (p=0.0020), consumption of fish (p=0.0002), consumption of legumes (p=0.002), consumption of green leafy vegetable (p<0.0001). Conclusion: Results confirmed an increased prevalence of IDA in women of reproductive age group.

scholarly journals Impact study of nutritional education as a controlling measure of iron deficiency anemia

2017 ◽  
Vol 4 (11) ◽  
pp. 4057
Author(s):  
Jayanta Saha ◽  
Sahana Mazumder Sen ◽  
Amalendu Samanta
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Control Group ◽  
Age Group ◽  
Deficiency Anaemia ◽  
And Control ◽  
Experimental Group ◽  
Reproductive Age Group

Background: Iron deficiency anaemia is one of the most common nutritional disorders world-wide, especially in India and other developing countries. Young children and women in the reproductive age group are the most vulnerable to iron deficiency anaemia. Part of the reason for this lack of action is the fact that iron deficiency anaemia (IDA) has few overt symptoms. Hence this study have been undertaken to see the impact of nutritional counselling as a controlling measure of IDA.Methods: Rural women of reproductive age group were first screened for anemia and then for IDA. Two groups were formed one experimental group who were given nutritional counselling and another group designated as control group devoid of any such counselling. Baseline haematological indicators were estimated along with dietary surveys in both the groups. Haematological estimation and dietary survey was carried out again after six months and those women in experimental group still found to be anemic were again counselled, the procedure was repeated again at twelve months and at the end of the study that is eighteen months. Data’s were then statistically analysed for finding significant between the groups.Results: Our study showed statistically significant differences in haematological indicators between the experimental and control group at the end of the study. Intake of nutrition also showed statistically significant differences between the experimental and control group at the end of the study.Conclusions: Intervention only with iron and folic supplements is not adequate to tackle iron deficiency anemia problem. Therefore, there is a need to use interventions measures like nutritional education approaches for addressing major preventable causes of anemia. 

scholarly journals The potential effect of iron defortification on iron-deficiency anaemia in the US population

2007 ◽  
Vol 10 (11) ◽  
pp. 1266-1273 ◽  
Author(s):  
Min Tao ◽  
David L Pelletier ◽  
Dennis D Miller
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Potential Effect ◽  
Reproductive Age ◽  
Iron Nutrition ◽  
Deficiency Anaemia ◽  
Adult Men ◽  
The Us ◽  
The Usa

AbstractObjectiveTo quantify the potential effect of iron defortification in the USA on iron-deficiency anaemia (IDA).MethodsMonte Carlo models were built to simulate iron nutrition in the US population. A hypothetical cohort of 15 000 persons from the general population was used in 15-year simulations to compare the prevalence of IDA with and without fortification.ResultsWith iron fortification, the prevalence of IDA was 2.4% for children aged 3–5 years, 5.4% for women aged 20–49 years, and 0.14% for men aged 20–49 years. The corresponding IDA estimates under iron defortification were 4.5%, 8.2% and 0.46%, respectively. Defortification had little effect on the distribution of iron indicators at or above the 50th percentile within each of these three groups and little effect on the distributions of iron indicators among adult men.ConclusionIron defortification is likely to increase IDA among children and women of reproductive age, but is not likely to have meaningful effects on the iron status of men or the majority of women and children.

scholarly journals Systematic review to investigate the safety of induction and augmentation of labour among pregnant women with iron-deficiency anaemia

BMJ Open ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. e021793 ◽  
Author(s):  
Kathryn Bunch ◽  
Nia Roberts ◽  
Marian Knight ◽  
Manisha Nair
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anaemia ◽  
Case Reports ◽  
Case Series ◽  
Severe Anaemia ◽  
Risk Of Bias ◽  
Deficiency Anaemia ◽  
Increased Risk

ObjectiveTo conduct a systematic review to investigate the safety of induction and/or augmentation of labour compared with spontaneous-onset normal labour among pregnant women with iron-deficiency anaemia.DesignSystematic review.SettingStudies from all countries, worldwide.PopulationPregnant women with iron-deficiency anaemia at labour and delivery.InterventionAny intervention related to induction and/or augmentation of labour.Outcome measuresPrimary: Postpartum haemorrhage (PPH), heart failure and maternal death. Secondary: Emergency caesarean section, hysterectomy, admission to intensive care unit.MethodWe searched 10 databases, including Medline and Embase, from database inception to 1 October 2018. We included all study designs except cross-sectional studies without a comparator group, case reports, case series, ecological studies, and expert opinion. The searches were conducted by a healthcare librarian and two authors independently screened and reviewed the studies. We used the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approachto ascertain risk of bias and conducted a narrative synthesis.ResultsWe identified 3217 journal articles, 223 conference papers, 45 dissertations and 218 registered trials. Ten articles were included for full-text review and only one was found to fulfil the eligibility criteria. This was a retrospective cohort study from India, which showed that pregnant women with moderate and severe anaemia could have an increased risk of PPH if they underwent induction and/or augmentation of labour, but the evidence was weak (graded as ‘high risk of bias’).ConclusionThe best approach is to prevent anaemia, but a large number of women in low-to-middle-income countries present with severe anaemia during labour. In such women, appropriate peripartum management could prevent complications and death. Our review showed that at present we do not know if induction and augmentation of labour is safe in pregnant women with iron-deficiency anaemia and further research is required.PROSPERO registration numberCRD42015032421.

scholarly journals Effectiveness of a Nutritional Education Intervention Focussed on Iron among School Children in National Capital Region and Mumbai

2021 ◽  
Author(s):  
Richa Bharti ◽  
Ankita Marwaha ◽  
Teena Badshah ◽  
Rupali Sengupta ◽  
Bhavna Barmi ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
School Children ◽  
Iron Deficiency Anaemia ◽  
Iron Absorption ◽  
Age Group ◽  
Nutritional Education ◽  
Post Intervention ◽  
Deficiency Anaemia ◽  
Alternate Hypothesis

Introduction: Anaemia is a major health problem in India. Various studies mention poor nutrition knowledge and education as main factors of malnutrition. Aim: This study aims at assessing the effect of nutritional education on iron among school children. Materials and Methods: A cross-sectional interventional study to improve nutrition literacy in schools was undertaken from April 2018 to February 2019. The outreach platform used was Eat Right School program by Food Safety and Standards Authority of India (FSSAI). A study tool employed was data collection using self-developed questionnaire for pre and post-intervention knowledge assessment. School children from Delhi NCR and Mumbai participated in this study. Knowledge intervention was done on 5 key elements related to iron including role, sources, iron deficiency anaemia, iron absorption and knowledge of fortification. Chi-squared test (α=0.05) was applied for comparison. Results: It was found that 54% (n=18,626) of school children studied were in the age group 11-14 years. From 27355 participants who reported the gender, 58.1% (n=15899) were boys and 41.9% (n=11456) girls. Comparison of pre and post-intervention assessment revealed that percentage of students knowing importance/role of iron increased from 27.30% to 59.50%, iron deficiency anaemia from 34.03% to 59.85%, sources of iron from 25.20% to 51.70%, iron absorption from 36.00% to 61.2% and knowledge of fortification from 55.4% to 76.9%. Thus, significant shift (p≤0.001) in all the parameters was observed; improvement in scores ranged from 21.5% to 32.20% with highest increase seen in understanding the role of iron. Conclusion: Results of the study reject the null hypothesis leading to acceptance of alternate hypothesis. The alternate hypothesis highlights the role of nutrition education in improving the nutritional literacy of school children in the area of iron and iron deficiency anaemia. Results of the current study increased the knowledge of children on all parameters related to iron education module. Thus, nutritional literacy is imperative in improving nutritional status and adolescent age-group is the window of opportunity to correct it.

scholarly journals Comparative study of efficacy and safety of parenteral iron sucrose versus ferric carboxymaltose in treatment of postpartum iron deficiency anaemia

2021 ◽  
Vol 11 (1) ◽  
pp. 100
Author(s):  
Ganesh N. Dakhle ◽  
Mrunalini V. Kalikar ◽  
Rujuta P. Fuke ◽  
Anisha S. Parmarthi ◽  
Mrunalini K. Chokhandre
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Iron Deficiency Anaemia ◽  
Maximum Dose ◽  
Iron Sucrose ◽  
Ferric Carboxymaltose ◽  
Care Hospital ◽  
Deficiency Anaemia ◽  
Iron Stores ◽  
Parenteral Iron

Background: Postpartum anaemia often leads to multiple clinical complications in mother as well as infant and iron supplementation with parenteral iron is the preferred treatment modality. The present study was planned to compare the efficacy and tolerability of IV iron sucrose and IV ferric carboxymaltose in treatment of postpartum iron deficiency anaemia.Methods: This randomized, parallel, open label, prospective 4-weeks study was conducted from June 2019 to December 2020 in women with postpartum anaemia admitted to obstetrics and gynaecology inpatient department of a tertiary care hospital. Women with postpartum iron deficiency anaemia (N=60) were randomly divided into two groups; receiving Injection iron sucrose (N=30, maximum dose 500 mg) or Injection ferric carboxymaltose (N=30, maximum dose 500 mg). Change in haemoglobin and serum ferritin levels from baseline to the end of 2 and 4 weeks of treatment were evaluated.Results: The results showed early, sustained and significant increase in the haemoglobin levels in both the groups. However, the difference was not significant between groups (p=0.2). Evaluation of replenishment of iron stores (serum ferritin) showed improvement in both the groups, however in FCM group the rise was found to be significant (p<0.05).Conclusions: FCM in a lower dose of 500mg was found to be safe and effective in significantly improving haemoglobin concentration as well as in replenishing iron stores in patients with postpartum anaemia.

scholarly journals Prevalence and spectrum of iron deficiency anaemia in heart failure patients

2019 ◽  
Vol 7 (1) ◽  
pp. 132
Author(s):  
Gaurav Mohan ◽  
Gurinder Mohan ◽  
Manish Chandey ◽  
Avneet Kaur ◽  
Trimaan Singh Sikand ◽  
...  
Keyword(s):  
Heart Failure ◽  
Iron Deficiency ◽  
Serum Ferritin ◽  
Iron Deficiency Anaemia ◽  
Large Scale ◽  
Binding Capacity ◽  
Tertiary Care ◽  
Transferrin Saturation ◽  
Care Hospital ◽  
Deficiency Anaemia

Background: To study the prevalence and pattern of iron deficiency (ID)in heart failure (HF) patients with or without anaemia.Methods: This is a single-centre observational study, conducted at a tertiary care hospital of Punjab. Patients were selected based on validated clinical criteria-Framingham criteria. The iron parameters were done during the study including serum iron, serum ferritin, total iron binding capacity, and transferrin saturation (TSAT), to diagnose iron deficiency anaemia. Anaemia was defined as haemoglobin (Hb) < 13g/dl in males and <12 g/dL in females, based on WHO definition. Absolute iron deficiency is defined as serum ferritin < 100 mg/L and functional ID was defined as normal serum ferritin (100–300 mg/L) with low TSAT (<20%).Results: A total of 120 patients of Heart Failure (54% males and 46% females) were studied. Most of the patients were of high-functional NYHA class (Class IV NYHA n=45). Iron Deficiency was present in 60% patients with 31.66% patients having absolute and 28.33% patients having functional ID. Nearly one-fifth of the patients were having ID but without anemia, signifying importance of workup of Iron deficiency other than haemoglobin levels.Conclusions: Study highlights the neglected burden of ID in HF patients in India. This study suggests further large-scale studies to better characterize this easily treatable condition and considering routine testing in future Indian guidelines.

scholarly journals Nutrition Knowledge is Associated With the Consumption of Iron Rich Foods: A Survey Among Pregnant Women From a Rural District in Northern Ghana

2021 ◽  
Vol 14 ◽  
pp. 117863882110394
Author(s):  
Nhyira Yaw Adjei-Banuah ◽  
Victor Abugah Aduah ◽  
Shamsu-Deen Ziblim ◽  
Martin Amogre Ayanore ◽  
Anthony Amalba ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anaemia ◽  
Nutrition Knowledge ◽  
The Body ◽  
Rural District ◽  
Leafy Vegetables ◽  
Health Concern ◽  
Deficiency Anaemia ◽  
Increased Risk

Introduction: Iron deficiency anaemia is an international public health concern and pregnant women are at an increased risk. We investigated the consumption of iron rich foods and associated factors among pregnant women in a rural district from Ghana. Methods: Following a cross-sectional design, dietary intake of iron rich foods was obtained from 252 pregnant women using a 24-hour recall food check list. Nutrition knowledge, attitudes and socio-demographic characteristics were also assessed. Findings: Participants had a mean (SD) knowledge score of 54.66 (22.74)%. About 73% of the participants had heard about iron-deficiency anaemia. Only 16.3% of the participants knew foods that help the body to absorb and use iron while 9.1% knew beverages that decrease iron absorption. About 71% of the participants ate fish and/or seafood while 67.1% of them ate green leafy vegetables. Only 4.4% of the participants ate organ meat, and 29% took flesh meat. Only 22.4% of the study participants usually drank coffee or tea while 78.2% ate vitamin C-rich foods. With regards to attitudes, 88.5% of the participants perceived anaemia to be a serious disease. Nutrition knowledge was significantly associated with the consumption of iron rich foods (β = .02; 95% CI = 0.01-0.02). Conclusion: Nutrition knowledge may be an important determinant of the consumption of iron rich foods among pregnant women making it necessary for healthcare providers to continue to provide nutrition education to pregnant women during routine antenatal care.

"A clinical study to assess efficacy of rasapachaka kashaya in rasapradoshaja vyadhi - panduroga (iron deficiency anaemia) in females in reproductive age."

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
Sonal Lohiya
Keyword(s):  
Clinical Study ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Modern Science ◽  
Reproductive Age ◽  
Muscle Cramp ◽  
Deficiency Anaemia ◽  
Blood Indices ◽  
Significant Difference ◽  
Loss Of Appetite

Background: Pandu is a Rasa Pradoshaja Vyadhi described by Acharya Charaka. Pandu causes extreme debility as it is dominated by the symptoms like Palpitation, Fatigue, Dyspnoea on exertion etc, due to the vitiation of Rasa and Rakta Dhatu, which are the essential factors for nourishment of body. There is a correlation of Pandu with Anaemia of Modern science. Females in reproductive age are more susceptible for Iron Deficiency Anaemia due to regular menstrual flow and dietary inadequacies and ultimately suffer complications in pregnancy as well in delivery. The present clinical study was conducted to assess efficacy of Rasapachaka Kashaya in Rasapradoshaja Vyadhi - Panduroga (Iron Deficiency Anaemia) in females in reproductive age. Methods: Total 30 female patients of Panduroga in the age group 18-45 years were selected randomly. The study subjects were given Rasapachaka Kashaya in the dose of 1 gm twice a day after meals. Total study duration was of 90 days and assessment was done before initiation of study and at the end of every month. Results: The relief in symptom scores such as Panduta (Pallor), Hrutspandan (Palpitation), Shunakshikut (Periorbital oedema), Daurbalya (Weakness), Hatanal (Loss of Appetite), Arohanayas (Exhaustion during climbing), Pindikodveshta (Calf muscle cramp), Aruchi (Anorexia), Shrama (fatigue), Bhrama (giddiness) and Nidralu (Sleepiness) symptom was statistically significant (p < 0.01). Statistically significant difference was observed in objective parameters such as Haemoglobin level and RBC count (p < 0.05 and < 0.001 respectively) also in PCV and MCMC after 3 months of treatment. No significant improvement was noticed in blood indices such as MCV and MCH. WBC count found to be improved to significant level whereas ESR showed decline to statistically significant level. No significant change in Platelet count was seen over a period of three months, i. e. completion of treatment. Conclusion: The Rasapachaka Kashaya is found to be effective in the management of Rasapradoshaja Vyadhi– Panduroga in females in reproductive age.

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