scholarly journals Hematological and biochemical studies on hemodylitic patients at the Government General Hospital, Wadi Al-Dawaser

2020 ◽  
Vol 6 (2) ◽  
pp. 31
Author(s):  
Somia A. Nassar ◽  
Zeinb A. Yehia ◽  
Alaa A. Alnami ◽  
Alanood N. Aldosari ◽  
Sara M. Abdullah ◽  
...  
Keyword(s):  
Renal Failure ◽  
General Hospital ◽  
Biochemical Parameters ◽  
Serum Glucose ◽  
The Body ◽  
Dialysis Unit ◽  
Hematological Indices ◽  
Hospital Patients ◽  
Serum Biochemical ◽  
The Government

<p class="abstract"><strong>Background:</strong> Renal failure is a slowly progressive disease of kidney, characterized by low glomerular filtration. One of the most important replacement therapy of renal failure is hemodialysis which helping in the removal of toxic fluids and metabolic end products from the body.</p><p class="abstract"><strong>Methods:</strong> This study was carried out on 43 patients with renal failure in the dialysis unit of Wadi Al-Dawaser General Hospital. Patients were 25 males and 18 females, randomly selected for the study between September and November 2018. Blood samples were obtained from all patients pre and post dialysis for serum biochemical analysis including kidney function test, liver function, lipid profile, glucose, electrolytes, while blood sample with anticoagulants collected pre dialysis for complete blood picture.  </p><p class="abstract"><strong>Results:</strong> The hemogram parameters recorded significant decrease while leuckogram insignificantly increase specially eosinophils, in pre-dialysis patients. Serum biochemical parameters were significantly high pre-dialysis recorded 83.7%, 97.7%, 21% for urea, creatinine and uric acid respectively, while significantly decrease post dialysis. In contrast serum glucose and magnesium levels were significantly high pre and post dialysis. As result of decrease of the erythropoietin production in chronic renal failure patients lower hematological indices, increase the risk of anemia are main results.</p><p class="abstract"><strong>Conclusions:</strong> Dialysis improve the biochemical parameters of serum especially creatinine and urea while glucose and magnesium not improved.</p><p class="abstract"> </p>

Effect of graded levels of nucleotide supplementation on certain serum biochemical parameters in Japanese quails

2016 ◽  
Author(s):  
S. Prakash ◽  
Jyoti Palod ◽  
R. K. Sharma ◽  
S. K. Singh
Keyword(s):  
Biochemical Parameters ◽  
Protein Profile ◽  
Hdl Cholesterol ◽  
Serum Glucose ◽  
Serum Biochemical Parameters ◽  
Treatment Groups ◽  
Japanese Quails ◽  
Randomized Design ◽  
Serum Biochemical ◽  
G Ratio

A trial was conducted for a period of 6 weeks to evaluate the effect of graded levels of nucleotide supplementation on serum biochemical parameters in Japanese quails. In the trial, 3 day old Japanese quail chicks were randomly distributed in completely randomized design into 4 treatment groups each with 3 replicates of 10 Japanese quails. The Japanese quails of treatment groups T1, T2, T3 and T4 were provided feed containing 0, 0.5, 1.0 and 1.5 per cent nucleotide respectively for a period of six weeks. At the end of experiment blood samples were collected for study of serum-biochemical parameters. The results indicated that decreased serum glucose, serum cholesterol and LDL cholesterol and increased HDL cholesterol was noticed in nucleotide supplemented groups at higher levels. Protein profile showed significant improvement in total protein, albumin and globulin while A/G ratio revealed no effect of supplementation. Serum creatinine and SGPT contents showed non-significance whereas, serum uric acid and SGOT contents were significantly (P<0.05) reduced in nucleotide supplemented groups of quails. It is concluded that nucleotide supplementation improves serum biochemical parameters without affecting liver and kidney functions.

Bioavailability and preliminary toxicity evaluations of alumina nanoparticles in vivo after oral exposure

2012 ◽  
Vol 1 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Sheng-Tao Yang ◽  
Tiancheng Wang ◽  
Erya Dong ◽  
Xin-Xin Chen ◽  
Kun Xiang ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
The Body ◽  
Alumina Nanoparticles ◽  
Oral Exposure ◽  
Alumina Powder ◽  
Essential Trace Elements ◽  
Body Weights ◽  
Serum Biochemical ◽  
Low Toxicity

Abstract Alumina nanoparticles (NPs) are among the most important nanomaterials and are widely used in diverse areas. In this study, we evaluated the bioavailability and toxicity of alumina NPs in mice after oral exposure, compared with traditional alumina powder. Our results indicated that negligible alumina NPs were absorbed post-exposure and alumina NPs did not influence the balance of essential trace elements, including Fe, Cu and Zn. Preliminary toxicological evaluations suggested that alumina NPs were of low toxicity. The body weights were similar among the mice exposed to alumina NPs, alumina powder and 0.9% NaCl aqueous solution. The low toxicity was also indicated by the unchanged serum biochemical parameters. The implications related to the ongoing safety evaluations and applications of alumina NPs are discussed.

scholarly journals Comparative study of some Serum Biochemical parameters of cattle and sheep of the marshes in the south of Iraq

2010 ◽  
Vol 9 (2) ◽  
pp. 78 ◽  
Author(s):  
Kh. G. Al-Fartosi, Y. J. Talib, and Sh. Ali
Keyword(s):  
Biochemical Parameters ◽  
Serum Levels ◽  
Serum Glucose ◽  
The South ◽  
Male And Female ◽  
Significant Difference ◽  
Serum Biochemical ◽  
South Of Iraq ◽  
Female Cattle ◽  
Cattle And Sheep

This study includes the normal values of biochemical parameters of cattle and sheep lived in Marshes of the south of Iraq. The serum levels of glucose, urea, creatinine, cholesterol, triglyceride, total protein, albumin, globulin, calcium(ca), potassium(k), Aspartate aminotransferase(AST), Alanine aminotransferase (ALT), Alkaline phosphatase ( ALP) and Lactate dehydrogenase (LDH) were determined.T he results showed there are nonsignificant differences in all parameters of male cattle compared with a female, except the serum glucose which decreased significantly in male compared with female. There is a significant increase in cholesterol and potassium of male sheep compared with a female, whereas the other parameters did not show a significant difference (p<0.05) between them. also, the results indicated a significant increase in TG, cholesterol, AST, ALK, and LDH of male and female cattle compared with male and female sheep. There were no significant differences in other parameters.

scholarly journals Influence of modern treatment regimens on serum biochemical parameters in piglets with gastroenteritis

2020 ◽  
Vol 11 (1) ◽  
pp. 67-73
Author(s):  
B. O. Lukashchuk ◽  
L. G. Slivinska ◽  
A. R. Shcherbatyy ◽  
H. O. Zinko ◽  
B. V. Gutyj
Keyword(s):  
Biochemical Parameters ◽  
Serum Alkaline Phosphatase ◽  
Positive Influence ◽  
Serum Glucose ◽  
Serum Total Bilirubin ◽  
Weaned Piglets ◽  
Treatment Regimens ◽  
Cell Structures ◽  
Pig Farm ◽  
Serum Biochemical

The article presents analyses of biochemical parameters of blood serum in weaned piglets with non-contagious gastroenteritis and after their treatment with a probiotic (live spores of Bacillus cereus var. toyoi; silicic acid; calcium carbonate) and a phytobiotic (natural extracts of Oreganum vulgare, Cinnamomun cassia and Capsicum annuum; hydrogenated rapeseed oil) as part of the basic ration in combination with antibiotic (10% solution of enrofloxacin hydrochloride) on a modern pig farm. In animals of the experimental groups with gastroenteritis we established hypoproteinemia, hypoalbuminemia, hypoglycemia, hypoureaemia, hypercreatininemia, hyperbilirubinemia and increase of enzyme activity compared to parameters of clinically healthy piglets. The study established that the use of probiotics and phytobiotics for weaned piglets had a positive influence on protein synthesis function of the liver, as indicated by the normalization of serum total protein and albumins. Also, we found a positive influence of probiotics and phytobiotics on intensity of protein metabolism, as indicated by an increase of serum urea to the level of clinically healthy piglets. Use of phytobiotics for piglets had a positive influence on the process of gluconeogenesis in their body, which is indicated by the normalization of serum glucose to the level of clinically healthy piglets. Also, the use of probiotics and phytobiotics had a positive influence on the pigment-forming function of the liver, as indicated by the reduction of serum total bilirubin to the level of clinically healthy piglets. The use of probiotics and phytobiotics reduced activity of serum alanine and aspartate aminotransferases in the piglets of the experimental groups, indicating the stabilization of hepatocytes’ cell structures (mitochondrial and cytosolic). The study established positive influence of probiotics and phytobiotics on the functioning of the liver and biliary tract, as indicated by decreased activity of serum alkaline phosphatase and gamaglutamiltranspeptidase to the level of clinically healthy piglets. So, addition of probiotics and phytobiotics to mixed fodder up to 45 days of age, normalizes functioning of the kidneys and liver in weaned piglets with gastroenteritis.

scholarly journals CHRONIC KIDNEY DISEASE

2018 ◽  
Vol 25 (06) ◽  
pp. 887-891
Author(s):  
Tanveer Fatima ◽  
Aurangzeb Afzal ◽  
Sania Ashraf
Keyword(s):  
Renal Failure ◽  
The Body ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Waste Products ◽  
Dialysis Unit ◽  
Complex Procedure ◽  
Back Ache ◽  
Life Threatening ◽  
Stage Renal Disease

Introduction: Hemodialysis is a process of removal of waste products andtoxic substances from the body using an extracorporeal system. During the procedure, lotsof hemodynamic and metabolic changes occur in the body as a result of which patientsundergoing hemodialysis may suffer from complications both acutely during or just after dialysisas well as in long term. Objective: To determine the frequencies of various acute intradialyticcomplications in our hemodialysis patients. Study Design: Cross sectional survey. Setting:Lahore General Hospital, Lahore. Period: 3 months from May 2017 to July 2017. Method:End stage renal disease patients on regular hemodialysis in the dialysis unit of a tertiary carehospital. A total of 81 patients were included in the study. Patients with acute renal failure andacute on chronic renal failure were excluded from the survey. Results: Common complicationsobserved in our studied population included muscle cramps (70.7%), post dialysis fatigue(57.3%), back ache (56.1%), intradialytic shivering (57.3%), hypoglycemia (21.4%), hypotension(37.8%), hypertension (8.5%), headache (13.4%), vomiting (13.4%) and anaphylaxis in 2.4%.Conclusion: Hemodialysis is a complex procedure and can cause many complications mostof which are not life threatening. With proper monitoring and immediate treatment thesecomplications can be overcome without causing interruption in hemodialysis.

DOMINAN FACTORS RELATED TO QUALITY OF LIFE OF PATIENTS WITH END STAGE RENAL FAILURE UNDERGOING HEMODIALYSIS AT TABANAN GENERAL HOSPITAL

2018 ◽  
Vol 2 (2) ◽  
pp. 195
Author(s):  
Anselmus Aristo Parut ◽  
I Gusti Ayu Puja Astuti Dewi
Keyword(s):  
Quality Of Life ◽  
Renal Failure ◽  
General Hospital ◽  
Hemodialysis Patients ◽  
The Body ◽  
Dominant Factor ◽  
Life Questionnaire ◽  
End Stage Renal Failure ◽  
End Stage

Background : Renal failure is a clinical condition which irreversible reduction in renal function and need hemodialysis as replacement for kidney function. Hemodialysis is a dialysis that perform outsite the body. Indonesian Association Of Nephrology (Pernerfi) stated that new hemodialysis and active hemodialysis patients in Indonesia since 2007-2018 increased, 14.644 new hemodialysis patients and 7.276 active hemodialysis patients.Method : This is a descriptive analysis study with cross-sectional design and multiple logistic regression to identify dominant factor related to quality of life hemodialysis patients. Location of this research was Tabanan General Hospital. The sampling technique was nonprability sampling with total population were 166 patients. Data collected using insomnia questionnaire, family support questionnaire, quality if life questionnaire and complication observation form. Result : The result showed that, higher OR found in intra hemodialysis variabel (OR:180,917), which mean that intra hemodialysis complication is a dominan factor related to quality of life hemodialysis patients. Patients who had complication were more likely to have low quality of life. Further study are needed to identify factors related to intra hemodialysis complications.  Keywords : Dominan factors, intra hemodialysis complications, quality if life, end stage renal failure, hemodialysis.  

scholarly journals Sexual Maturity Promotes Yolk Precursor Synthesis and Follicle Development in Hens via Liver-Blood-Ovary Signal Axis

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2348
Author(s):  
Zhifu Cui ◽  
Felix Kwame Amevor ◽  
Qian Feng ◽  
Xincheng Kang ◽  
Weizhen Song ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Fatty Acid Synthase ◽  
Density Lipoprotein ◽  
Reproductive Hormones ◽  
The Body ◽  
Low Density ◽  
Serum Biochemical Parameters ◽  
Functional Changes ◽  
Precursor Synthesis ◽  
Serum Biochemical

Several reproductive hormones were reported to be involved in regulating egg yolk precursor synthesis in chickens; however, the mechanism that shows how the liver-blood-ovary signal axis works in relation to age changes has not been reported yet. Therefore, in this study, we observe the morphology and histology of the liver and ovary and determine the serum biochemical parameters and the expression abundance of the critical genes from d90 to 153. Results show that the body weight and liver weight were significantly increased from d132, while the ovary weight increased from d139. Aside from the increase in weight, other distinct changes such as the liver color and an increased deposition of large amounts of yolk precursors into the ovarian follicles were observed. On d139, we observed small fatty vacuoles in the hepatocytes. The results of serum biochemical parameters showed a significant increase in the estradiol (E2) level, first on d125, and then it reached its peak on d132. Meanwhile, the levels of follicle-stimulating hormone (FSH) increased initially and then remained at a high level from d146 to d153, while the levels of luteinizing hormone (LH) increased significantly on d132 and reached the top level on d153. Moreover, the levels of lecithin (LEC), vitellogenin (VTG), very low density lipoprotein y (VLDLy), triglyceride (TG), and total cholesterol (TC) were significantly increased at d125 and were close from d146 to d153. The mRNA and protein expression of estrogen receptor-alpha (ER-α) and E2 levels in the liver and serum, respectively, showed similar changes. Moreover, with reference to an increase in serum E2 level, the mRNA expression of genes related to yolk precursor synthesis (very low density apolipoprotein-II, ApoVLDL-II) and vitellogenin-II (VTG-II), lipogenesis (fatty acid synthase, FAS), and lipid transport (microsomal triglyceride transport protein, MTTP) in the liver showed up-regulation. These results suggest that the correlation between liver-blood-ovary alliances regulate the transport and exchange of synthetic substances to ensure synchronous development and functional coordination between the liver and ovary. We also found that E2 is an activator that is regulated by FSH, which induces histological and functional changes in the hepatocytes through the ER-α pathway.

scholarly journals Біохімічні зміни в сироватці крові свиней хворих на трихуроз

2015 ◽  
pp. 124-126
Author(s):  
В. В. Мельничук ◽  
О. С. Назаренко ◽  
С. І. Назаренко
Keyword(s):  
Blood Serum ◽  
Biochemical Parameters ◽  
Total Bilirubin ◽  
Smooth Muscles ◽  
Liver Parenchyma ◽  
Pathological Process ◽  
The Body ◽  
Indirect Bilirubin ◽  
Serum Biochemical ◽  
The Impact

Наведені результати гематологічних дослідженьщодо визначення впливу збудника трихурозу свинейна біохімічні показники сироватки крові інвазованихтварин. Встановлено, що паразитування трихурисівв організмі поросят призводить до достовірногозниження вмісту загального білка, альбумінів і зрос-тання вмісту загального білірубіну, непрямого біліру-біну й активності ферментів у сироватці крові.Отримані дані свідчать про залучення у патологіч-ний процес паренхіми печінки, серцевого м'яза і гла-денької мускулатури кишечника. The results of hematological studies to determine the impact of the pathogen of trichurosis of pigs on blood serum biochemical parameters infested animals are presented. We established that trichurises’ parasites in the body of pigs leads to a significant reduction of total protein, albumin and increase of total bilirubin, indirect bilirubin and enzyme activity in blood serum. These data suggest about involvement of liver parenchyma in the pathological process, cardiac muscle and smooth muscles of the intestine.

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