scholarly journals Analysis of Increased Caesarean Delivery in a Tertiary Centre in North Eastern Region of India- A Cross Sectional Observational Study

2019 ◽  
Vol 6 (42) ◽  
pp. 2746-2749
Author(s):  
Salilbindu Chakrabarti ◽  
Jayanta Ray ◽  
Arindam Mallik
Author(s):  
Hari Shankar ◽  
Sobhan Phookan ◽  
Mrigendra Pal Singh ◽  
Ram Suresh Bharti ◽  
Naseem Ahmed ◽  
...  

Abstract Background Malaria elimination requires targeting asymptomatic and low-density Plasmodium infections that largely remain undetected. Therefore we conducted a cross-sectional study to estimate the burden of asymptomatic and low-density Plasmodium infection using conventional and molecular diagnostics. Methods A total of 9118 participants, irrespective of age and sex, were screened for malaria using rapid diagnostic tests (RDTs), microscopy and polymerase chain reaction. Results Among the participants, 707 presented with symptoms and 8411 without symptoms, of which Plasmodium was present in 15.6% (110/707) and 8.1% (681/8411), respectively. Low-density infection was found in 5.1% (145/2818) of participants and 8327 of 9118 were Plasmodium negative. Endemicity was propotional to asymptomatic infections (high endemicity 11.1% [404/3633] vs low endemicity 5.8% [277/4778]; odds ratio [OR] 2.0 [95% confidence interval {CI} 1.7 to 2.4]) but inversely related to low-density infection (high endemicity 3.7% [57/1545] vs low endemicity 6.9% [88/1273]; OR 1.9 [95% CI 1.4 to 2.7]). The spleen rate in children 2–9 y of age was 17.9% (602/3368) and the enlarged spleen index was 1.6. Children between 8 and 14 y showed higher odds for asymptomatic (adjusted OR [aOR] 1.75 [95% CI 1.4 to 2.2]) and low-density infections (aOR 0.63 [95% CI 0.4 to 1.0)] than adults. Conclusions The prevalence of asymptomatic and low-density Plasmodium infection undermines the usefulness of standard diagnostic tools used by health agencies. This necessitates deploying molecular tools in areas where malaria microscopy/RDTs indicate a dearth of infection.


Author(s):  
Chandana Kalita ◽  
Anupam Sarma ◽  
Jagannath Dev Sharma ◽  
Manoj Kalita ◽  
Manigreeva Krishnatreya ◽  
...  

Background: Numerous studies have documented the association of the ABO blood groups with the occurrence of cancers. Aim was to find out an association of ABO blood groups and various cancers in the North Eastern region of India.Methods: The study was a retrospective observational study that included 1000 cases and 1000 controls. The data included the ABO blood typing of the selected cancer sites which were head and neck, esophagus, stomach, breast, cervix, and ovary. Patients who attended blood bank of regional cancer center with requisition for blood transfusion from 2014 to 2016 were included. The control group was healthy blood donors. Chi square test was used to assess the difference among the compared groups. Risk was calculated by regression analysis. P value <0.05 was considered as statistically significant at 95% confidence interval.Results: Out of 1000 cases and 1000 controls, O blood group were seen in 377 (37.7%) and 395 (39.5%) cases and control, respectively. Significant reduced odds ratio (OR) in non O blood groups for head and neck, esophagus, stomach, and breast was observed. In case of carcinoma cervix, OR for B group was 1.5 (P=0.05), and for blood group A OR=2.2 (P=0.02) was seen in carcinoma ovary.Conclusions: In the studied population, patients with O blood group are at an increased risk of developing head and neck, esophagus, stomach, and breast cancers.


BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e018823 ◽  
Author(s):  
Jianlin Zhao ◽  
Nan Shan ◽  
Xiaochang Yang ◽  
Qin Li ◽  
Yinyin Xia ◽  
...  

ObjectivesTo assess the influence of second child intent on the delivery preferences and final delivery modes of nulliparous women, particularly caesarean delivery on maternal request (CDMR), after implementation of China’s two child policy.DesignCross sectional and prospective observational study.SettingA tertiary teaching hospital in Chongqing, China.Participants1000 low risk nulliparous women were initially involved, and were divided into two groups based on their intent on having a second child. 814 women who completed all interviews were analysed.Main outcome measuresPreferred mode of delivery in second trimester and at admission; final delivery mode, CDMR.Results814 women who completed all interviews were analysed, in whom 51.2% intended to have a second child. The preference for caesarean delivery (CD) at the second trimester between the intent and no intent group was 6.2% versus 17.9% (adjusted RR 0.35, 95% CI 0.20 to 0.63) and increased to 24.2% versus 37.3% (adjusted RR 0.65, 95% CI 0.45 to 0.94) at admission, respectively. The overall CD rates between the two groups were 41.0% versus 50.4% (adjusted RR 0.84, 95% CI 0.60 to 1.18), and the CDMR rates were 16.7% versus 29.0% (adjusted RR 0.56, 95% CI 0.37 to 0.86), respectively.ConclusionsWomen who intend to have a second child are less likely to request a CD, and high rates of CD and CDMR in nulliparous women may have decreased after implementation of China’s two child policy.


2020 ◽  
Vol 7 (11) ◽  
pp. 3620
Author(s):  
Madhur Anand ◽  
Noor Topno ◽  
Ranendra Hajong ◽  
Anoop J. Baruah ◽  
Donkupar Khongwar ◽  
...  

Background: Ascaris lumbricoides is the largest intestinal nematode parasite of humans. This study describes different presentations and management patterns of gastrointestinal and hepato-pancreato-biliary ascariasis presenting to a tertiary centre of North-eastern India.Methods: This was a prospective observational study aimed to study the presentations and management patterns of Ascaris related surgical diseases including intestinal obstruction, pancreatitis and cholangitis in a tertiary centre of Northeast India. All consenting cases of gastrointestinal and hepato-pancreato- biliary ascariasis admitted in our hospital were included.Results: Ninty patients with Ascaris sequeale were included, which included biliary ascariasis without cholangitis: 36, pancreatitis: 30, cholangitis: 18 and sub-acute intestinal obstruction: 6. Ultrasound was the most useful diagnostic investigation followed by stool examination and endoscopy. Hepato-pancreato-biliary ascariasis was managed conservatively and the progress monitored with sonography. The surgical management choledocho-duodenostomy was done for three patients having biliary ascariasis with unresolving obstructive jaundice and recurrent cholangitis on conservative management and 6 patients underwent therapeutic endoscopic worm removal. There were no deaths. No patient needed ICU care.Conclusions: Sonography can be helpful in diagnosing the presence of worms, its complications and in evaluating response to treatment. Hepato-pancreato-biliary ascariasis can be managed conservatively for majority of the patients.


2021 ◽  
Vol 3 (3) ◽  
Author(s):  
Nagwa Ibrahim ◽  
Asma Almuhsin ◽  
Raghad Alkhattabi ◽  
Maryam Almulaifi ◽  
Ali Alrumaih

Introduction: COVID-19 pandemic impacted all countries negatively. Regulatory bodies in Saudi Arabia and worldwide set a firm policies and guidelines to protect their nationals and residents from the virus. Pharmacists play a major role in health care. This study aims to assess pharmacists prospective and general health wellbeing during COVID-19 pandemic in Saudi Arabia. Methods: We conducted a cross sectional observational study using a quantitative survey-based methodology. Data was collected from May to July 2020. Results: We were able to enrol 381 pharmacists working in different practice settings as governmental hospitals, healthcare centers, private hospitals and community pharmacies. The acceptable knowledge level score is 13 (60%) that has been reached by about 37% of participants. Male and female had similar scores. Level of knowledge among regions was variable, southern region scored the least with a mean score of 12.89 ± 3.91 and eastern region scored the highest level with a mean score of 15.07 ± 2.86. There was a significant correlation between knowledge level, region of residency and level of experience. The maximum total awareness score was 7, the mean score was 5.18 ± 1.65. There was a statistically significant correlation between awareness level and the region of residency variable. The general health questions section included 9 questions. The minimum score was 9, the maximum was 36 and the mean score was 17.51 ± 7.34. The higher the score indicate the worsening of the general health. There is a strong correlation between gender, experience and the general health wellbeing. Men had better general health compared to women p<0.001 and participants with range of experience 6-10 years had a lower level of general health. Conclusion: COVID-19 still has a negative impact worldwide. Maintaining awareness and education is essential to keep the protective measures as possible. In addition, there is a need to address the impact of COVID-19 on pharmacist's mental health to act accordingly.


2020 ◽  
Vol 2 (4) ◽  
Author(s):  
N Thilly ◽  
O Pereira ◽  
J Schouten ◽  
M E J L Hulscher ◽  
C Pulcini

Abstract Background We previously developed proxy indicators (PIs) that can be used to estimate the appropriateness of medications used for infectious diseases (in particular antibiotics) in primary care, based on routine reimbursement data that do not include clinical indications. Objectives To: (i) select the PIs that are relevant for children and estimate current appropriateness of medications used for infectious diseases by French paediatricians and its variability while using these PIs; (ii) assess the clinimetric properties of these PIs using a large regional reimbursement database; and (iii) compare performance scores for each PI between paediatricians and GPs in the paediatric population. Methods For all individuals living in north-eastern France, a cross-sectional observational study was performed analysing National Health Insurance data (available at prescriber and patient levels) regarding antibiotics prescribed by their paediatricians in 2017. We measured performance scores of the PIs, and we tested their clinimetric properties, i.e. measurability, applicability and room for improvement. Results We included 116 paediatricians who prescribed a total of 44 146 antibiotic treatments in 2017. For all four selected PIs (seasonal variation of total antibiotic use, amoxicillin/second-line antibiotics ratio, co-prescription of anti-inflammatory drugs and antibiotics), we found large variations between paediatricians. Regarding clinimetric properties, all PIs were measurable and applicable, and showed high improvement potential. Performance scores did not differ between these 116 paediatricians and 3087 GPs. Conclusions This set of four proxy indicators might be used to estimate appropriateness of prescribing in children in an automated way within antibiotic stewardship programmes.


2009 ◽  
Vol 12 (12) ◽  
pp. 2428-2437 ◽  
Author(s):  
Pierre Valeix ◽  
Patrice Faure ◽  
Sandrine Péneau ◽  
Carla Estaquio ◽  
Serge Hercberg ◽  
...  

AbstractObjectiveTo assess dietary iodine intakes among adults and to investigate the relationships of dietary, lifestyle, demographic and geographical characteristics with dietary iodine status. Adequacy of iodine intakes was also assessed.DesignCross-sectional study. Linear regression analyses and logistic regression modelling were used to determine correlates of iodine intakes. Usual iodine mean intake was calculated by averaging six 24 h dietary records completed over a 2-year period.SubjectsFemales aged 35–60 years (n 2962) and males aged 45–60 years (n 2117) living in France and who participated in the SU.VI.MAX study.ResultsIodine intakes ranged from 30·0 to 446·3 μg/d. The median iodine intake was 150·7 μg/d for males and 131·4 μg/d for females. High-level (97·5th percentile) intakes were 273·4 μg/d for males and 245·0 μg/d for females. Overall, 8·5 % of males and 20·3 % of females had intakes <100 μg/d (P < 0·001). Alcohol drinkers and smokers tended to have lower iodine intakes than abstainers or non-smokers. Regular physical activity and both intermediate and high education levels were associated with a lower risk of iodine intake of <150 μg/d. For both males and females there were significant overall regional differences (P < 0·001) in multivariate-adjusted iodine intakes, with higher adjusted iodine intakes in Brittany and Normandy than in the north-eastern region.ConclusionsOur data show a borderline low iodine intake in this middle-aged French population. However, differences in iodine intakes may contribute to explaining only a small part of the effects of sex and age on thyroid disease incidence.


2021 ◽  
Vol 8 (1) ◽  
pp. 165-169
Author(s):  
SM Abdullah ◽  
Uday Kumar Mohanta

A cross sectional study was conducted to estimate the prevalence and identify possible risk factors (season, sex) of Schistosoma in three north-eastern districts of Bangladesh namely Mymensingh, Sunamganj, Kishoreganj. Mesenteric sample of cattle from different slaughter houses were collected and examined for helminths which were identified as Schistosoma on accordance with Soulbsy, 1965. Total 67 (55.83%) out of 120 randomly selected samples were found positive for schistosomiasis. Cattle of Kishoreganj were mostly infected (67.50%), followed by Sunamganj (55.00%) and Mymensingh (45.00%). Regarding seasonal prevalence, samples collected during winter (63.33%) were more infected than summer (48.33%). Moreover, 58.69% of male and 46.42% of female were found infected. In conclusion, relatively high prevalence was recorded in the study areas based on the results obtained. Hence, control measures against schistosomiasis must be designed. Res. Agric., Livest. Fish.8(1): 165-169, April 2021


Author(s):  
Rikrak Ch Marak ◽  
T. Achouba Singh

Background: The disease is endemic in many parts of India, especially in the North- Eastern region. A study was done on head of the family’s knowledge, attitude and practice regarding malaria and long-lasting insecticidal bed nets and to determine the association between socio-demographic profile and knowledge and attitude.Methods: A cross-sectional study was conducted in the communities from 3 subcentres namely Pearsonmun, Thingkhangpai and Soipum under Saikot PHC, Churachandpur district of Manipur. House to house survey was carried out and only those who are eligible were interviewed using structured questionnaire. Random sampling and PPS was carried out to select the households head. SPSS was used for analysis.Results: Total of 289 heads of the family was interviewed. The total adequate knowledge score was 30.6% and only 26.3% had favourable attitude towards malaria and long-lasting insecticidal bed nets. There was significant association between marital status, educational qualification, occupation and monthly income with adequacy of knowledge. There was significant association between religion and attitude.Conclusions: Majority of the participants still lacks knowledge and attitude towards the malaria and long-lasting insecticidal nets (LLIN). IEC and awareness campaign should be carried out intensively and further study to be done to see the improvement of knowledge. 


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