scholarly journals THE EFFECTIVENESS OF APHARM A COLOGICAL COMPOUND BASED ON SILATIVIT AND PERCUTANEO US ELECTRONE UROSTIMUL ATION AFTER LASER CURET TAGE IN PATIENTS WITH CHRONIC PERIODONTITIS

2013 ◽  
Vol 9 (1) ◽  
pp. 25-28
Author(s):  
Е. Светлакова ◽  
E. Svetlakova ◽  
Ю. Мандра ◽  
J. Mandra ◽  
Н. Жегалина ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
High Frequency ◽  
Periodontal Diseases ◽  
Frequency Of Occurrence ◽  
Actual Problem ◽  
Dental Lasers ◽  
Percutaneous Electroneurostimulation

<p>Nowadays the treatment of periodontal diseases is an actual problem, that is caused by high frequency of occurrence of periodontopathies. diode dental lasers are nowadays often used for treatment periodontal pockets. Using hydrogel based on silativit and percutaneous electroneurostimulation healing of the wound surfaces.</p><p> </p><p> </p>

Comparative analysis of polymorphic variants of IL-17A and MMP-1 genes with the risk of developing chronic periodontitis in petrochemical workers

2020 ◽  
Vol 60 (10) ◽  
pp. 687-693
Author(s):  
Iskander I. Zaidullin ◽  
Denis O. Karimov ◽  
Lilija K. Karimova ◽  
Milyausha F. Kabirova ◽  
Rasima R. Galimova ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Control Group ◽  
Periodontal Tissues ◽  
Dental Examination ◽  
Number Of Patients ◽  
Increased Risk ◽  
Harmful Substances

The susceptibility to the development and progression of inflammatory periodontal diseases, which depends on genetic and external factors (smoking, stress, oral hygiene), varies widely. In the development of these diseases, an important role is played not only by the presence of periodontal pathogenic microorganisms, but also by the presence of congenital or acquired immunodeficiency, immunoregulatory defects. The immune system plays a key role in the physiological and pathological processes of periodontal tissues. In this regard, IL17, produced by CD4+ Th cells, which has both Pro-inflammatory and protective activity, is of particular interest in the pathogenesis of periodontitis. The aim of study was to identify the relationship between polymorphic loci of the IL-17A (rs2275913) and MMP-1 (rs1799750) genes and clinical manifestations of chronic periodontitis in petrochemical workers. Dental examination was performed in 92 ethylene oxide production workers with chronic periodontitis and 74 patients with chronic periodontitis who did not come into contact with chemical factors (control group). Genotyping of polymorphisms rs2275913 of the IL17A gene and rs1799750 of the MMP1 gene was performed by allele-specific real-time polymerase chain reaction (PCR). Hygienic assessment of the degree of air pollution of the working area with harmful substances was carried out by gas chromatography according to the guidelines for the determination of harmful substances in the air № 5098-89, № 3119-84. When comparing the results of studies of both groups, there were no statistically significant differences in the frequency distributions of allelic variants and genotypes of the IL-17A and MMP-1 genes. The AA/AG genotypes of the IL-17A gene were associated with an increased risk of severe disease compared to the GG genotype in workers in the main group (OR=6.1; 95% CI 1.33-28.5; p=0.021) and in the control group (OR=7.26; 95% CI 1.34-39.25; p=0.016). Carriers of the A allele in the control group increased the risk of severe chronic periodontitis by 2.4 times compared to carriers of the G allele (OR=2.41; 95% CI 1.19-4.87; p=0.014). During the dental examination of employees of the ethylene oxide plant, the clinical course of periodontal diseases was more severe in comparison with the control group, and the number of patients with severe periodontitis was twice as high. It was found that the AA/AG genotypes of the IL-17A gene and the carrier of the A allele are associated with increased susceptibility to the development of severe chronic periodontitis. The association between the MMP-1 gene polymorphism and the risk of severe forms of chronic periodontitis has not been established. A risk factor for the development of inflammatory periodontal diseases in employees of the petrochemical complex is a complex of harmful production factors.

Fungus Spaeropsis Malorum peck. One of the currant stalk drying agents

2020 ◽  
Vol 62 ◽  
pp. 172-178
Author(s):  
S. E. Golovin
Keyword(s):  
Causative Agent ◽  
High Frequency ◽  
Frequency Of Occurrence ◽  
Ribes Nigrum ◽  
Black Currant ◽  
Causative Agents ◽  
Pear Trees ◽  
Red Currant

The article highlights the results of research carried out in 2019-2020 to study the reasons for the drying out of the stems of black currant (Ribes nigrum L.), red currant (Ribes rubrum L.) and golden currant (Ribes aureum L.). As a result of research, the fungus Sphaeropsis malorum Peck. in the first in Russia it was revealed from the drying stems of three types of black currants, red currants and golden currants. This  pathogen inhabited currant stems together with fungi from the genus Cytospora spp., causative agents of stem drying. On red currants, it was established that S. malorum was the main causative agent of branch drying, as indicated by the high frequency of occurrence (75.0-83.3 %) of this fungus on the affected stems, compared with species from the genus Cytospora spp. (16.7-33.3 %) and Phomopsis ribesia (25.0 %). Due to the fact that the cultivation of currants in the immediate vicinity of apple and pear trees leads to infection of plants with the fungus S. malorum, it is necessary to avoid planting currants in the vicinity of fruit-bearing seed gardens.

Ultrastructural Changes of Candida albicans Species Induced by the Presence of Sodium Diclofenac

2017 ◽  
Vol 68 (11) ◽  
pp. 2566-2569 ◽  
Author(s):  
Elena Rusu ◽  
Ionela Sarbu ◽  
Magdalena Mitache ◽  
Horatiu Moldovan ◽  
Carmen Ioana Biris ◽  
...  
Keyword(s):  
Candida Albicans ◽  
High Frequency ◽  
Fungal Infections ◽  
Diagnostic Methods ◽  
Ultrastructural Changes ◽  
Frequency Of Occurrence ◽  
Medical Treatments ◽  
Sodium Diclofenac ◽  
Cell Wall Disruption ◽  
Candidiasis Treatment

The high frequency of occurrence of candidiasis as well as high mortality of patients with immunosuppression cause a tendency toward better understanding of Candida albicans species virulence factors and developing sensitive and specific diagnostic methods, and appropriate strategies of candidiasis treatment. In recent decades the incidence of fungal infections has alarming increases because of advanced medical treatments. In this study was analyzed possible ultrastructural changes of the species C. albicans cells following treatment with sodium diclofenac at various concentrations. Following treatment of C. albicans cells with sodium diclofenac 1 mM and 2 mM changes in the plasmalemma can be noticed, changes in the density of cell wall, disruption and necrotic appearance of the cytoplasm.

Comparative evaluation of genotoxic effect in subjects with chronic periodontitis with and without type 2 diabetes mellitus

2019 ◽  
Vol 11 (1) ◽  
pp. 29-36
Author(s):  
Dr.Smruti Lulla ◽  
Dr.Amita Mali ◽  
Dr. AashwiinMiglani ◽  
Dr. VidyaDodwad ◽  
Dr. SachinMangalekar ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Dna Damage ◽  
Type 2 Diabetes Mellitus ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Genotoxic Effect ◽  
Micronucleus Frequency ◽  
Group A

Aims: The aim of the study was to compare the genotoxic effect by assessing the micronucleus frequency (MNF), as a biomarker for DNA damage, in subjects with chronic periodontitis with and without type 2 Diabetes Mellitus. Methods and Material: For the study, a total of 65 subjects were take and divided into three groups. Group A included 30 subjects with Generalised Chronic Periodontitis, Group Bincluded 30 Subjects with Chronic Periodontitis with type 2 diabetes mellitus and Group C included 5 systemically and periodontally healthy subjects. Periodontal clinical examination was carried out. A slide was prepared using the blood sample collected from the subjects which was fixed in 5% geimsa solution and was observed under the microscope. Later the scoring of micronuclei was done. Statistical analysis used: Descriptive and inferential statistical analyses were carried out in the present study. Analysis of Variance (ANOVA) was used to find the significance of study parameters and test the equality of three or more means of more than two groups. Tukey’s post hoc analysis was used to compare parameters of each and every group. Results: The mean score of the micronuclei observed in group A, B and C were 10.23, 14.87 and 1 respectively i.e. group B showed significantly greater damage than other two groups. Conclusions: It was concluded that the score of micronucleus frequency may be considered as an important biomarker of genotoxic damage that is DNA damage in subjects with chronic localised as well as systemic diseases like type 2 diabetes, as well as Periodontal diseases.

scholarly journals Correlation of ABO Blood Groups and Rh Factor with The Severity of Generalized Chronic Periodontitis: Across Sectional Study in Riyadh, Saudi Arabia

2019 ◽  
Vol 7 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Diana Mostafa ◽  
Essam I. Elkhatat ◽  
Pradeep Koppolu ◽  
Muna Mahgoub ◽  
Esam Dhaifullah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Blood Group ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group I

BACKGROUND: The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases. AIM: Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor. METHODS: A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever). RESULTS: The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive. CONCLUSION: Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.

scholarly journals Seasonal variation on diet of juvenile Elops saurus Linnaeus, 1766 (Ladyfish) in the Parnaiba River Delta

2020 ◽  
Vol 32 ◽  
Author(s):  
Tatiane Araujo Santos ◽  
Thamires Souza Gonçalves ◽  
Patricia Silva do Nascimento ◽  
Cézar Augusto Freire Fernandes ◽  
Francisca Edna de Andrade Cunha
Keyword(s):  
High Frequency ◽  
Rainy Season ◽  
Stomach Contents ◽  
Dry Season ◽  
River Delta ◽  
Frequency Of Occurrence ◽  
Relative Importance ◽  
Dry Period ◽  
Food Items ◽  
Importance Index

Abstract: Aim Identify seasonal variations in the diet of juvenile living in the estuary of the Parnaíba River Delta. Methods Food items were identified through analysis of stomach contents, and later submitted to analysis by regular methods for Frequency of Occurrence (FO), Frequency Numerical (FN), Gravimetric Frequency (FW) and Relative Importance Index (IRI). Results Juvenile diet of Elops saurus that inhabit the lagoons in the Parnaíba delta was composed in order decreasing of importance by Osteichthyes (Teleostei), Insecta and Crustacea in addition to Polychaeta and Nematoda. It was also observed a high frequency of occurrence of fragments of plastics in the diet. In the rainy season, 17 items were recorded in the diet, whereas in the dry season only 7 items were present. Relative Importance Index showed high presence of the Teleostei fish (69.93%) on diet of E. saurus during the rainy season, whereas during the dry period the insects of the families Corixidae (43.25%) and Dysticidae (39.16%). Conclusions With the study it was possible to identify that juvenile are piscivorous in the rainy season when there is a higher availability of prey in the environment and insectivores in the dry season when it reduces the supply of food, indicating feeding flexibility to environmental alterations.

Application of Plant-Based Preparations in a Comprehensive Treatment of Inflammatory Periodontal Diseases

2021 ◽  
Vol 6 (5) ◽  
pp. 38-44
Author(s):  
O. D. Saliuk ◽  
◽  
P. H. Gerasimchuk ◽  
L. O. Zaitsev ◽  
I. I. Samoilenko ◽  
...  
Keyword(s):  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
The Body ◽  
Comprehensive Treatment ◽  
Complex Treatment ◽  
Medicinal Products ◽  
Actual Problem ◽  
Periodontal Tissues ◽  
Wide Range ◽  
Anti Inflammatory

In this article the review of foreign and domestic literary sources, which are devoted to the actual problem of modern dentistry – the treatment of inflammatory diseases of periodontal tissues: gingivitis and periodontitis are presented. The complex approach to their treatment involves the appointment of a significant amount of pharmacotherapeutic drugs. Therapeutic failures and iatrogenic complications have led to the fact that today the interests of doctors and population to medicinal products significantly increased. The purpose of the study is to analyze the data of scientific literature on the use of plant-based medicinal products for the treatment of periodontal inflammatory diseases over the past 10 years. Materials and methods. Comprehensive and systematic analysis of literature. Review and discussion. The analysis of information sources on the use of plant-based medicinal products in dentistry both independently and in the composition of medical and prophylactic means has established that the modern assortment of plant-based preparations in the pharmaceutical market of Ukraine to a certain extent is limited. The emergence of new plant-based species that have been tested in conditions of experimental pathology and require an evidence-based clinical base is noted. The composition of plant-based preparations used for the treatment of inflammatory periodontal diseases include vitamins, biologically active substances, glycosides, alkaloids, in connection with a wide range of action: antiseptic, anti-inflammatory, regenerating, hemostatic, antioxidative. The data on plant-based preparations that are most often used such as chamomile extracts, calendula, hypericum, plantain, kalanchoe, aloe, eucalyptus, milfoil, nettle, calamus and plant-based species are summarized. The medicinal agents considered are mainly recommended for local treatment of periodontal diseases in the form of dental care means, mouth rinse, gel, chewing gum, herbal liquer. It is known that the complex treatment of periodontal diseases includes a general influence on the body. The properties of green tea with its wide range of actions are investigated. With antioxidant properties, it can be a healthy alternative for controlling destructive changes in periodontal diseases. Attention is drawn to the proposed unique natural complex “Resverazin” due to a wide range of pharmacological action, low toxicity and relative safety. The drug produces antioxidant, anti-inflammatory, immune stimulating, vasodilative, neuroprotective action. Conclusion. Based on the literature analysis, it can be concluded that the accumulated experimental and clinical data on the therapeutic properties of plants prove perspective of their use in the complex treatment of inflammatory periodontal diseases. Future studies are mandatory for further confirmation of the effectiveness of these medicinal plants

PATIENT SELECTION FOR THE LASER TREATMENT BY ESTIMATION OF THE THERAPEUTIC FAILURE PROBABILITY OF SURGICAL TREATMENT

2021 ◽  
pp. 122-128
Author(s):  
Vyrmaskin S.I. ◽  
Trunin D.A. ◽  
Afanasev V.V.
Keyword(s):  
Surgical Treatment ◽  
Periodontal Diseases ◽  
Exponential Model ◽  
Multidimensional Analysis ◽  
Traditional Use ◽  
Dental Instruments ◽  
Probability Estimates ◽  
End Of Treatment ◽  
Dental Lasers ◽  
High Degree

The study is dedicated to the study of inflammatory and destructive periodontal diseases. Predicting the probability of a favorable outcome or treatment failure is one of the most important doctor’s tasks when choosing a particular method. This problem could not be solved without using a large amount of data characterizing the patient's condition at a particular point in time. The empirical approach to this problem depends largely on individual experience and does not imply obtaining any formalized (numerical) probability estimates of successful or, on the contrary, unsuccessful end of treatment. Correct and effective using of dental lasers in clinical practice requires knowledge of their effects on tissues of the oral cavity. Each type of laser has its properties that are used to solve clinical cases. Laser radiation requires an approach that is significantly different from the traditional use of dental instruments. To determine lasers therapeutic indications for the treatment of inflammatory and destructive periodontal diseases, we applied biometric approaches to the development of mathematical models using multidimensional analysis, allowing to obtain qualitative assessments for optimization of method and treatment strategy selection. The development of predictive models was carried out in several stages. Each of the generally accepted dental signs characterizing periodontal disease could not be a reliable criterion for the effectiveness or ineffectiveness of surgical treatment. Comprehensive assessment using a logistic (exponential) model of the probability of a particular treatment outcome with a high degree statistical reliability makes it possible to select patients for whom treatment with laser technologies is recommended.

scholarly journals Minibars in the Centers of Normal Galaxies

1996 ◽  
Vol 157 ◽  
pp. 207-211
Author(s):  
A. V. Zasov ◽  
O. K. Sil’chenko
Keyword(s):  
High Frequency ◽  
Spiral Galaxies ◽  
Velocity Fields ◽  
Frequency Of Occurrence ◽  
Gas Velocity ◽  
Ionized Gas ◽  
Normal Galaxies ◽  
Normal Spiral

AbstractAnalysis of ionized gas velocity fields in the circumnuclear regions of 13 normal spiral galaxies has shown that about half of them reveal a discrepancy between the kinematical axis at R < 2″ and the photometric or kinematical axes of the outer regions. This result indicates a high frequency of occurrence of non-axisymmetric gravitational potentials in the inner few hundred parsecs of galaxies. The possible nature of these minibars is discussed.

scholarly journals Salivary Melatonin and the Severity of Attachment Loss: A Case-Control Study

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Leila Golpasand-Hagh ◽  
Faramarz Zakavi ◽  
Arash Daraeighadikolaei ◽  
Akram Ahangarpour ◽  
Sara Hajati ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Healthy Subjects ◽  
Type I Collagen ◽  
Periodontal Diseases ◽  
Protective Role ◽  
Enzyme Linked Immunosorbent Assay ◽  
Blood Levels ◽  
Melatonin Level ◽  
Type I ◽  
Salivary Melatonin

Background. Melatonin (MT: N-acetyl-5-methoxytryptamine) is a neuroendocrine hormone secreted mainly by the pineal gland in the brain. MT is produced with a circadian rhythm characterized by elevated blood levels during the night. In healthy individuals, maximal secretion of MT occurs between midnight and 2:00 am, whereas the minimal production occurs during the day. MT can be determined by repeated measurement of plasma or salivary MT or urine sulfatoxy-melatonin. Melatonin has powerful antioxidant effects, has an immunomodulatory role, stimulates the synthesis of type I collagen fibers, and promotes bone formation. Melatonin is also secreted in the saliva, although its role in the mouth is not known well. The purpose of this study was to examine the correlation between salivary melatonin level and periodontal diseases. Methods. Fifty subjects by mean age of 40.44±6.38 years were equally divided into 5 groups: 10 healthy subjects, 10 subjects with gingivitis, 10 subjects with localized moderate chronic periodontitis, 10 subjects with generalized moderate chronic periodontitis, and 10 subjects with generalized severe chronic periodontitis. Saliva samples were collected from all the subjects and melatonin levels were determined using an enzyme-linked immunosorbent assay. Two-way and one-way ANOVA and Tukey test were used to analyze relationships among variables. Results. Healthy subjects had significantly higher salivary melatonin level (5.29±0.50 pg/mL) compared to patients with gingivitis (4.35±0.30 pg/mL) (P<0.001). The difference between salivary melatonin level in patients with gingivitis and periodontitis was significant (P<0.001). Level of melatonin in patients with generalized severe chronic periodontitis (3.39±0.10 pg/mL) was significantly lower than that in other groups (P<0.01). Conclusions. This study determined that salivary melatonin level in patients with periodontal diseases is lower than that in healthy subjects. Consequently we conclude that there is a negative correlation between melatonin level and the severity of disease, suggesting that melatonin might have a protective role against periodontal diseases, although further research is required to validate this hypothesis.

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