scholarly journals Prevalence of Metabolic Syndrome and its Related Risk Factors in the City of Oran, Algeria: the ISOR Study

2016 ◽  
Vol 26 (1) ◽  
pp. 99 ◽  
Author(s):  
Leila Houti ◽  
Imane Hamani-Medjaoui ◽  
Sarah A. Lardjam-Hetraf ◽  
Hadjira Ouhaibi-Djellouli ◽  
Saada Chougrani ◽  
...  

<p><strong>Background</strong>: Aging and lifestyle changes had led to an  epidemiological transition, with a significant impact on the incidence of cardiovascular diseases in North Africa. <br /><strong></strong></p><p><strong>Objective</strong>: The aim of this study was to determine the prevalence of metabolic syndrome and its associated factors, which were unknown, among an urban population in Algeria.</p><p><strong>Methods:</strong> During 2007-2009, 787 individuals aged 30-64 years, randomly selected from the list of insured persons residing in the city of Oran, participated in a clinical, anthropometric and biological survey. Participants were classified according to the National Cholesterol Education Program - Adult Treatment Panel (NCEP-ATP) III definition of metabolic syndrome.<br /><strong></strong></p><p><strong>Results</strong>: The prevalence of metabolic syndrome was 20%, higher in women than men (25.9 vs 13.7%; P&lt;.0001). Among the<br />components of the syndrome, the most common risk factors observed in women were a low high-density lipoprotein (HDL) cholesterol concentration (60.4% vs 44.2% in men) and abdominal obesity (46.8% vs 30.1% in men) whereas men displayed more high blood pressure (42.5% vs 34.8% in women). In men, metabolic syndrome was more frequent in married and highly educated participants. In contrast, women with a high level of education and who had an intermediate level of physical activity seemed to be protected.<br /><strong></strong></p><p><strong>Conclusions</strong>: Metabolic syndrome, prevalent in the urban population of North Algeria, is associated with a high proportion of low HDL-cholesterol and abdominal obesity, especially among women. There is a need for prevention strategies involving promotion of physical activity for the whole population and screening for hypertension among men. <em>Ethn Dis</em>. 2016;26(1):99-106; doi:10.18865/ed.26.1.99</p>

2020 ◽  

Background and objective: Managing the decrease in physical function in the elderly is a major task in aging societies globally. Here, we aimed to compare the physical function and metabolic syndrome (MetS) risk factors according to levels of physical activity (PA). Material and methods: We measured PA in 77 elderly Korean men (74.21 ± 6.26 years old) with an accelerometer and recorded body composition, physical function, and MetS-related risk factors. Participants were divided into three groups based on daily moderate-vigorous physical activity (MVPA): low (under 60 min), middle (60-120 min), and high (over 120 min). The groups were compared using a one-way analysis of variance and the Scheffe post hoc test. Odds ratios (OR) were calculated by logistic regression analysis. Results: Significant differences were found between the groups for sedentary behavior time (P < 0.001), light PA (P < 0.05), moderate PA (P < 0.001), vigorous PA (P < 0.05), and total energy expenditure (P < 0.001). The high PA group showed a significantly lower percentage of body fat and fat mass and higher muscle mass than did the low and middle PA groups (P < 0.05). The 6-min walk test was significantly better in the high PA group than in the low and middle PA groups (P < 0.05). Grip strength and the Berg balance scale were also significantly better in the high PA group (P < 0.05). Bone mineral density (BMD) and high-density lipoprotein cholesterol (HDL-C) were significantly higher in the high PA group than in the low PA group (P < 0.05). Systolic blood pressure (SBP) was significantly higher in the middle PA group than in the low PA group (P < 0.05). Participants with more than three MetS criteria showed an OR of 0.09 (95% confidence interval 0.01-0.82) in the high PA group as compared with the low PA group (P < 0.05). Conclusions: Moderate-vigorous physical activity of more than 120 min daily showed better physical function and lower OR of MetS than did lower MVPA levels in elderly Korean men.


Background. Nowadays the importance of lifestyles in the prevention of type 2 diabetes and the metabolic syndrome has been largely accertained. Objective. The purpose of our work is to implement programs that promote a nutritional culture in adolescents and young adults of the La Sabana University. Methods. The methodology entailed, after the corresponding informed consent, taking measures of the triceps and supraescapular skinfolds, waist circumference, body mass index (BMI), lean mass, and fat mass. Fasting blood samples were also taken to quantify cholesterol, triglycerides, high density lipoprotein (HDL) and low density lipoprotein (LDL). Results. The results obtained show that of the 165 students, 10.3% were underweight, 13.93% were overweight and 0.6% were obese. With regards to gender, 4.8% of the men and 9% of the women were overweight, 3% of the men and 7.2% of the women were underweight, and 0.6% of the women were obese. The blood chemistry showed that 30% had hypercholesterolemia, 18% hypertriglyceridemia, 17% reported low HDL levels and 67% reported high LDL levels. Of all the cases studied, 40% are at risk of a metabolic syndrome. 60% claimed not to practice any physical activity - especially women who reported 44.70%. Conclusions. These findings have allowed us at the institution to implement a culture of healthy habits. The have also allowed us to identify students with risk factors for type 2 diabetes and metabolic syndrome. This is why the cardiometabolic monitoring and control based on healthy eating and physical activity are important.


Author(s):  
Jos Twisk ◽  
Isabel Ferreira

The incidence of morbidity and mortality related to CVD is rather low in a paediatric population. Studies investigating the relationship between physical activity, physical fitness, and cardiovascular health in children and adolescents are therefore mostly limited to CVD risk factors as outcome measures. For this reason, this chapter will focus on the association of physical activity and physical fitness with CVD risk factors in children and adolescents. These risk factors can be divided into the so-called traditional CVD risk factors; that is, lipoproteins [total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides (TG)], blood pressure, body fatness, and diabetes, and ‘new’ CVD risk factors; that is, other lipoproteins [lipoprotein(a) (Lp(a)), apolipoprotein (apo)B, and apoA-1], coagulation and inflammation markers [fibrinogen, C-reactive protein (CRP)], homocysteine, and heart rate variability.


2015 ◽  
Vol 12 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Aristides M. Machado-Rodrigues ◽  
Neiva Leite ◽  
Manuel J. Coelho e Silva ◽  
João Valente-dos-Santos ◽  
Raul A. Martins ◽  
...  

Background:Associations of metabolic syndrome (MetS) with lifestyle behaviors in youth is potentially important for identifying subgroups at risk and encourage interventions. This study evaluates the associations among the clustering of metabolic risk factors and moderate-to-vigorous physical activity (MVPA) in youth.Methods:The sample comprised 522 girls and 402 boys (N = 924) aged 11 to 17 years. Height, weight, waist circumference (WC), fasting glucose, high-density lipoprotein cholesterol, triglycerides, and blood pressures were measured. Cardiorespiratory fitness (CRF) was assessed using the 20-m shuttle run test. MVPA was estimated with a 3-day diary. Outcome variables were statistically normalized and expressed as z scores. A clustered metabolic risk score was computed as the mean of z scores. Multiple linear regression was used to test associations between metabolic risk and MVPA by sex, adjusted for age, WC, and CRF.Results:After adjustment for potential confounders, MVPA was inversely associated with the clustering of metabolic risk factors in girls, but not in boys; in addition, after adjusting for WC, the statistical model of that relationship was substantially improved in girls.Conclusion:MVPA was independently associated with increased risk of MetS in girls. Additional efforts are needed to encourage research with different analytical approach and standardization of criteria for MetS in youth.


2021 ◽  
Vol 8 ◽  
Author(s):  
A. Bestavashvili Afina ◽  
S. Glazachev Oleg ◽  
A. Bestavashvili Alexander ◽  
Dhif Ines ◽  
Suvorov Alexander Yu ◽  
...  

Background: Patients with metabolic syndrome (MS) tend to suffer from comorbidities, and are often simultaneously affected by obesity, dysglycemia, hypertension, and dyslipidemia. This syndrome can be reversed if it is timely diagnosed and treated with a combination of risk factors-reducing lifestyle changes and a tailored pharmacological plan. Interval hypoxic-hyperoxic training (IHHT) has been shown as an effective program in reducing cardiovascular risk factors in patients with MS even in the absence of exercise. However, the influence of IHHT on the lipid profile and inflammation in this clinical population remains relatively unknown.Methods: A prospective, single-center, randomized controlled trial was conducted on 65 (33 men) patients with MS aged 29–74 years, who were randomly allocated to the IHHT or control (sham) experimental groups. The IHHT group completed a 3-week, 5 days/week intermittent exposure to hypoxia and hyperoxia. The control (sham) group followed the same protocol but was breathing room air instead. The primary endpoints were the lipid profile (concentrations of total cholesterol [TC], low-density lipoprotein [LDL], high-density lipoprotein [HDL], and triglycerides [TG]) and the inflammatory factors such as high-sensitivity C-reactive protein (hs-CRP), galectin-3, heat shock proteins (Hsp70). The secondary endpoints were alanine aminotransferase (ALT), aspartate aminotransferase (AST), N-terminal pro-hormone of brain natriuretic peptide level (NTproBNP), transforming growth factor beta-1 (TGF-beta1), heart-type fatty acid-binding protein (H-FABP), and nitric oxide synthase 2 (NOS2).Results: There were no differences between the two groups but the different baseline values have affected these results. The IHHT group demonstrated pre-post decrease in total cholesterol (p = 0.001), LDL (p = 0.001), and TG levels (p = 0.001). We have also found a decrease in the CRP-hs (p = 0.015) and Hsp70 (p = 0.006) in IHHT-group after intervention, and a significant decrease in pre-post (delta) differences of NTproBNP (p &lt; 0.0001) in the IHHT group compared to the control group. In addition, the patients of the IHHT group showed a statistically significant decrease in pre-post differences of ALT and AST levels in comparison with the control group (p = 0.001). No significant IHHT complications or serious adverse events were observed.Conclusions: The IHHT appears to improve lipid profile and anti-inflammatory status. It is a safe, well-tolerated procedure, and could be recommended as an auxiliary treatment in patients suffering from MS, however, the experiment results were limited by the baseline group differences.Clinical Trial Registration:ClinicalTrials.gov, identifier [NCT04791397]. Evaluation of the effect of IHHT on vascular stiffness and elasticity of the liver tissue in patients with MS.


2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
F. Sharifi ◽  
S. N. Mousavinasab ◽  
M. Saeini ◽  
M. Dinmohammadi

Objectives. We determine the prevalence of the metabolic syndrome in an urban population of Zanjan, a province located to the west of Tehran.Methods. Randomly selected adults>20 years were studied using stratified sampling. Target study sample was 2941 (1396 males and 1545 females). Metabolic syndrome was diagnosed using Adult Treatment Panel-III (ATP-III) guidelines when any three of the following were present: central obesity, raised triglycerides≥150 mg/dl, low high-density lipoprotein (HDL) cholesterol, blood pressure≥130/≥85 mm Hg, and diabetes or fasting plasma glucose (FPG)≥100 mg/dl.Results. Metabolic syndrome was present in 697 (23.7%) subjects (CI 95%:22%–25%,P= .001), prevalence was 23.1% in men and 24.4% in women (P: .4). The prevalence increased from 7.5% in the population younger than 30 y to 45.6% in ages more than 50 years. Low HDL was the most common metabolic abnormality in both sexes. Most of those with metabolic syndrome had three components of the syndrome (75.6%), 170 subjects (24.4%) had four and none had five components simultaneously. The prevalence of obesity (BMI≥30 kg/m2), hypercholesterolemia (≥200 mg/dl) and high LDL cholesterol (≥130 mg/dl) was greater in the metabolic syndrome group than normal subjects (P= .00).Conclusions. There is a high prevalence of metabolic syndrome in this urban population of the northern west of Iran. Focus of cardiovascular prevention should be undertaken in this area.


Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3415
Author(s):  
Sangwon Chung ◽  
Min-Yu Chung ◽  
Hyo-Kyoung Choi ◽  
Jae Ho Park ◽  
Jin-Taek Hwang ◽  
...  

Few studies have examined the relationship of protein intake by food source with metabolic syndrome in Korean adults, even though animal food intake has increased. This study examined the association between plant and animal protein intake and metabolic syndrome among middle-aged Korean adults. A total of 13,485 subjects aged 30–64 years were selected from the 2013–2018 Korea National Health and Nutrition Examination Survey. Protein intake was assessed using 24-h dietary recall data and divided into quintiles. Men had a higher percentage of energy intake from animal protein (7.4%) than plant protein (6.9%). Men in the highest quintile group of animal protein intake had a higher prevalence of abdominal obesity (OR: 1.30, 95% CI: 1.00–1.70), reduced high-density lipoprotein cholesterol (HDL-C) (OR: 1.43, 95% CI: 1.07–1.90), and elevated fasting glucose (OR: 1.32, 95% CI: 1.01–1.74), after adjusting for covariates. Furthermore, stronger associations of animal protein intake with abdominal obesity were shown in men who consumed less than estimated energy requirements (OR: 1.60, 95% CI: 1.11–2.31). Plant protein intake was negatively associated with increased blood pressure in men. Neither animal nor plant protein intakes were significantly associated with any of the metabolic syndrome risk factors in women. The results imply that lower animal protein intake may be a beneficial factor for metabolic syndrome management in middle-aged Korean men.


2020 ◽  
Vol 3 (1) ◽  
pp. 11-17
Author(s):  
Limor Ben-Yacov ◽  
Pearl Ainembabazi ◽  
Aliza Hannah Stark ◽  
Samuel Kizito ◽  
Silver Bahendeka

Background and aimsIn sub-Saharan Africa, infectious diseases are still the leading causes of mortality; however, this may soon be surpassed by non-communicable illnesses, namely hypertension, diabetes and cardiovascular disease. This study determined the prevalence and patterns of metabolic syndrome and cardio-risk factors in men and women in rural Uganda.MethodsA household-based, cross-sectional survey was carried out following the WHO STEP-wise approach to surveillance. It included demographic and lifestyle questionnaires, anthropometric measurements and biochemical analyses. Of the 200 randomly recruited participants, 183 successfully completed two steps of the study and 161 provided blood samples.ResultsData were collected from 183 adults, aged 18–69 years; 62% were female. Based on the National Cholesterol Education Program-Adult Treatment Panel-III criteria, the prevalence of metabolic syndrome was 19.1% (95% CI 14.0 to 22.5). Elevated fasting plasma glucose was observed in 14.2% (95% CI 9.1 to 19.3) of participants, hypertriglyceridaemia in 16.9% (95% CI 12.1 to 23.1); hypertension in 36.1% (95% CI 29.0 to 43.0) and 52.5% (95% CI 45.2 to 59.6) had low HDL (high-density lipoprotein) cholesterol. Abdominal obesity was found in 24.6% (95% CI 18.8 to 31.4) of participants. Sex disparities were significant for several risk factors. Females had significantly higher prevalence of abdominal obesity (38.6% vs 1.5% in males, p=0.001) and twice the rates of low HDL (65.8% vs 30.4%, p=0.001). Men tended to have higher but not significant rates of hypertension (42.0% vs 32.5%) and smoked significantly more than women (49.3% vs 21.1%, p<0.001). Alcohol consumption was also higher in men (55.1% vs 18.4%, p<0.001) and quantities consumed were approximately three times greater than in females (p<0.001).ConclusionMetabolic syndrome exists at worrying rates in the rural Ugandan population. Sex disparities are evident in risk factor prevalence, reflecting physiological variables and deeply entrenched cultural and lifestyle norms.


2016 ◽  
Vol 4 (1) ◽  
pp. 25
Author(s):  
Fila Fatmisua Chrisna ◽  
Santi Martini

Stroke is one of non-communicable diseases and affected by many risk factors. Some stroke risk factors have in common with the metabolic syndrome criteria, such as abdominal obesity, glucose intolerance, decreased HDL cholesterol, elevated triglyceride levels, and insulin resistance. The goals to analyze the relationship between the metabolic syndrome with the incidence of stroke. This research is analytic by using case-control design. The case groups were hospitalized patients of stroke and undergoing inpatient in dr. M. Soewandhie Surabaya. The case groups were 32 peoples and control group 32 peoples were selected at random. The variables studied were age, sex, metabolic syndrome, the first criteria, the second criteria of metabolic syndrome, and the third criteria of metabolic syndrome. The results showed that the majority of stroke patients in the age range 51-75 years (78%). Results of Chi-Square test indicates a significant relationship between the metabolic syndrome criteria first (abdominal obesity, triglycerides, and HDL cholesterol levels) p = 0,01 OR = 6,82 (95% CI = 1,23 to 68,17 ) and the second criteria of metabolic syndrome (HDL cholesterol, blood pressure, and fasting glucose levels) p= 0,007 OR = 5,80 (95% CI = 1,30 to 35,15) with the incidence of stroke. While for the third criteria of metabolic syndrome (fasting glucose levels, abdominal obesity, triglyceride  levels) there was no significant relationship to the incidence of stroke. It is expected for people, especially over the age of 35 years can do a lipid profile and circle abdominal measurements to detect of   metabolic syndrome and the risk of stroke.Keywords: Metabolic Syndrome, Stroke, Abdominal Obesity, Triglyceride, HDL


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Bita Bijari ◽  
Toba Kazemi ◽  
Adib Movahedi ◽  
Mahmoud Zardast ◽  
Reyhane Hoshyar

Background: High-density lipoprotein cholesterol (HDL-C) as an invaluable predictor is used to determine the risk of heart diseases and evaluate the effectiveness of lipid-lowering therapies. Objectives: In this study, we aimed to investigate the association between HDL cholesterol level and some cardiovascular risk factors in the patients referring to the Heart Clinic of Birjand, Iran, during 2016 - 2017. Methods: In this cross-sectional study, 410 patients referring to the Heart Clinic of Birjand, Iran, during 2016 - 2017 were selected. Then using a questionnaire, complete demographic and biochemical data were collected and statistically analyzed for assessing the effects of some lifestyle factors such as the diet and physical activity on the serum level of HDL. Finally, all the results were analyzed by SPSS software (version 15). Results: In our study, the majority of dyslipidemic people had low levels of HDL (58.8%). Most of the participants were in a poor health condition according to BMI and physical activity, in a moderate health status in terms of smoking and cholesterol and fasting blood glucose (FBS) levels, and finally in the ideal health group in terms of the diet and blood pressure. The HDL level was significantly associated with physical activity, FBS, BMI, and blood pressure (P < 0.05). Conclusions: Considering the association between persistent cardiovascular risk factors and HDL cholesterol level, encouraging people to adopt a healthy lifestyle can help prevent cardiac diseases.


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