Prevalence Proportion of Patient with Coronary Heart Disease in Inpatient Room of RSUD Dr. Soetomo Surabaya in 2017

Introduction: Coronary heart disease (CHD) is the most common type of heart disease that causes death. It occurs as a result of hardening of the coronary arteries which supply oxigen-rich blood to the entire heart muscle so that the heart can contract properly. However, many patients neglect the symptoms. Moreover, the risk factor and the comorbides disease worsen the condition. This research aims to study the profile of coronary heart disease patients in the inpatient rooms at Dr. Soetomo General Hospital Surabaya in 2017.Methods: This study was a cross-sectional and retrospective study by assessing patients’ medical record and analyzed descriptively.Results: From total 587, 263 patiens met inclusion criteria, aged between 51-60 years (42.6%) with domination of male (82,13%). %). Risk Factors are into one of the Comorbidities of CHD Patient. There are Risk Factor can be aggravate of CHD Patients. Most of subjects had risk factor hipertension (50,79%), and hypertension with DM (38,7%). Hypertension based on systolic pressure and diastolic pressure obtained that systolic pressure <120 mmhg was 39.6% and diastolic pressure <80 was 37.4%.Conclusion: Most of CHD patients in this study were in age group 51 – 60 years old, male, had risk factor hypertension and DM.

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PREVALENCE OF HYPERTENSION AND TREATMENT OUTCOME IN TERTIARY CARE

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i10.601 ◽

2019 ◽

Vol 3 (1) ◽

Author(s):

Dr. Rajendra Prasad Gupta ◽

Dr. Satish Chandra Arya

Keyword(s):

Blood Pressure ◽

Coronary Heart Disease ◽

Risk Factor ◽

Heart Disease ◽

High Blood Pressure ◽

Resistant Hypertension ◽

Tertiary Care ◽

Hypertensive Crisis ◽

Normal Weight ◽

Age Group

INTRODUCTION: High blood pressure (BP) is ranked as the third most important risk factor for attributable burden of disease in south Asia. Raised blood pressure is a major risk factor for chronic heart disease, stroke, and coronary heart disease. WHO rates hypertension as one of the most important causes of premature death worldwide[i]. In India 57% of all stroke deaths and 24% of all coronary heart disease (CHD) deaths are due to hypertension. Other than coronary heart disease and stroke, complications include peripheral vascular disease, heart failure, renal impairment, retinal hemorrhage, and visual impairment. MATERIAL AND METHODS: Study population was adult patients who had been receiving anti-hypertensive treatment at hospital for at least 6 months. Interviews were conducted with all the participants and the questionnaires were filled. Demographic and anthropometric data were obtained for the patient who includes height and weight, BMI (Body Mass Index), personal medical history was obtained, and diagnosis of hypertension and other co-morbid conditions were recorded. RESULTS: A total of 200 patients were included in this study were observed and traced up to 6 month period of the study. 200 patients were included in the study of which 117 (58.50%) were male and 83 (41.50%) were female. Mean age of male patients was 52 ± 18.29 while in female it was 53 ± 17.88. We have divided our patients into four groups in <20 years only one male patient (0.85%) was having hypertension. In 20 – 39 years age group 16 (13.67%) male and 8 (9.63%) female were observed. In 40 to 59 age group 47 (35.04%) male and 31 (37.35%) female were observed. In >60 age group there were 53(45.30%) male and 44 (53.01%) female were observed. Maximum number of cases were observed in the >60 age group in both the sexes. 46 male (39.32%) and 35(42.17%) female had history of hypertension with Less than 5 years. while 71 (60.68%) male and 48 (57.83%) female had hypertension for more than five years. Out of 117 male 13 (11.11%) were normal weight, 85 (72.65%) were overweight and 19 (16.24%) were obese. In female 4 (4.82%) were normal weight, 69 (85.13%) were overweight and 10 (12.50%) were obese. Hypertension was most prevalent in overweight group in both the sexes. Diabetes was observed in 71 (60.68%) male and 56 (67.47%) female. 46 (39.32%) male and 27(32.53%) of female had myocardial infarction. Before start of the study 68 (58.12%) had controlled blood pressure, 42 (35.90%) had uncontrolled BP, Hypertensive crisis was seen in 5 (4.27%) patients and Resistant hypertension was seen in 2 (1.71%) cases. After study period 58 (49.57%) had controlled blood pressure, 22 (18.80%) had uncontrolled BP, Hypertensive crisis was seen in 2 (1.71%) patients and Resistant hypertension was seen in 1 (0.85%) case. CONCLUSION: Chronic uncontrolled high blood pressure which can be reduced by proper management, counselling and lifestyle modification. Prevalence of hypertension in males was slightly higher than female counterparts .Control of hypertension was more in female patients. Also patient assessment should be improved in order to increase the identification and management of hypertension KEYWORDS: Hypertension, Diabetes, coronary heart disease (CHD), management.

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Diabetes Mellitus in Patients with Coronary Heart Disease

Medicine Today ◽

10.3329/medtoday.v25i2.17923 ◽

2014 ◽

Vol 25 (2) ◽

pp. 67-68

Author(s):

Chaklader Md Kamal Jinnah ◽

Md Aminul Haque Khan ◽

Golam Morshed Molla ◽

Md Rezwanur Rahman ◽

M Iqbal Arslan

Keyword(s):

Diabetes Mellitus ◽

Coronary Heart Disease ◽

Risk Factor ◽

Heart Disease ◽

Premature Death ◽

Developed Countries ◽

Cross Sectional Study ◽

Modifiable Risk Factor ◽

Cross Sectional ◽

Medicine Today

Coronary heart disease is the most common form of heart disease and single most important cause of premature death in developed countries. It is estimated that coronary heart disease will become the major cause of death in all regions of the world by 2020. There are several modifiable risk factors of coronary heart disease. Among those diabetes mellitus is one major modifiable risk factor. So we designed this study to see the frequency of diabetes mellitus in patients with coronary heart disease in three tertiary hospitals in Bangladesh with an objective to see the frequency of diabetes mellitus in patients with coronary heart disease. This observational cross-sectional study was conducted in the department of Biochemistry of Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2006 to June 2007. The study was done among 300 purposively selected diagnosed patients of coronary heart disease of both sexes. Diabetes mellitus was diagnosed according to WHO criteria. In this study we found that 23.7% of study subjects had diabetes mellitus. From this study, it can be concluded that the prevalence of diabetes (an important modifiable risk factor) is high in coronary heart disease patients. DOI: http://dx.doi.org/10.3329/medtoday.v25i2.17923 Medicine Today 2013 Vol.25(2): 67-68

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Smoking Is a Risk Factor of Coronary Heart Disease through HDL-C in Chinese T2DM Patients: A Mediation Analysis

Journal of Healthcare Engineering ◽

10.1155/2020/8876812 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8

Author(s):

Ru Tang ◽

Shanshan Yang ◽

Weiguo Liu ◽

Bo Yang ◽

Shuang Wang ◽

...

Keyword(s):

Coronary Heart Disease ◽

Logistic Regression ◽

Regression Analysis ◽

Risk Factor ◽

Heart Disease ◽

Logistic Regression Analysis ◽

Mediation Analysis ◽

Smoking Status ◽

Density Lipoprotein ◽

Cross Sectional

Objective. To investigate associations between smoking and cardiovascular and cerebrovascular complications in type 2 diabetes mellitus (T2DM) patients. Methods. This is a cross-sectional study. Of 971 T2DM patients aged 14–93 years old in this study, 182 had ever smoked and 789 never smoked. Propensity score matching (PSM) reduced the confounding bias between groups. Logistic regression analysis was performed on matched data to evaluate coronary heart disease (CHD) and stroke risk. In addition, the mediation analysis was conducted among smoking exposure, HDL-C, and CHD. Results. A total of 139 pairs of patients who had never and ever smoked were matched. Logistic regression analysis showed that compared with patients who never smoked, those who smoked > 20 cigarettes per day (CPD) had a higher risk of CHD (odds ratio [OR]: 3.09, 95% confidence interval [CI]: 1.21–7.89). Additionally, after adjusting for age, sex, origin, occupation, smoking status, body mass index, waist circumference, and diabetes duration, the OR for CHD with >20 years of cumulative smoking (pack-years) was 2.21 (95% CI: 1.05–4.65). Furthermore, we observed a significant dose-response relationship between CPD and lower high-density lipoprotein cholesterol (HDL-C) (P<0.001). Moreover, the mediation analysis showed that the indirect effect mediated by HDL-C accounted for 86% (effect = 0.0187, 95% CI: 0.0100–0.0316). Conclusions. Smoking may be a risk factor for CHD in T2DM patients. T2DM patients should stop smoking or reduce the CPD to prevent the onset of CHD. Moreover, to prevent CHD complications, monitoring HDL-C levels in T2DM patients who smoke may be necessary.

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Apolipoprotein E as Risk Factor for Coronary Heart Disease

Indonesian Journal of Biotechnology ◽

10.22146/ijbiotech.7867 ◽

2015 ◽

Vol 18 (1) ◽

pp. 42

Author(s):

Pramudji Hastuti ◽

Abdul Salam M. Sofro ◽

Ahmad Husain Asdie ◽

Ahmad Hamim Sadewa

Keyword(s):

Coronary Heart Disease ◽

Risk Factor ◽

Heart Disease ◽

Apolipoprotein E ◽

Allelic Variation ◽

Gene Carrier ◽

Cross Sectional ◽

Key Words Apolipoprotein E ◽

Apoe Ε4 ◽

Apo E

Allelic variation of apolipoprotein E (apo E) has been shown to infl uence the concentrations of total cholesterol and low density lipoprotein cholesterol (LDL-C) and considered to play a role as one of risk factors for coronary heart disease (CHD). The aim of this study was to examine the relationship between Apo E polymorphism and the risk of CHD. Blood samples were collected from 33 CHD patients in Dr. Sardjito Hospital Yogyakarta, and 38 apparently healthy control individuals in a cross sectional study. The common allelic variants of ApoE were screened employing polymerase chain reaction and restriction fragment length polymorphism. The results obtained were analyzed by t-test and signifi cantly different if p <0.05 and risk factor was calculated by odd ratio. Frequency of ApoE ε2, ε2 and ε4 alleles in CHD patients were 12.1%, 69.7% and 18.2% while in controls were 18.4%, 72.4% and 9.2% respectively. Dyslipidemia condition was a strongrisk factor for CHD. By controlling lipid profi le and applying multifactorial statistic analysis, it was shown that ε4 gene carrier was the risk factor for CHD, but not in triglyceride level, whereas ε2 carrier gene was not the risk factor for CHD. Dislipidemia was the risk factor for CHD and ApoE ε4 gene carrier was the risk factor for CHD. Key words: apolipoprotein E, ApoE ε4 gene carrier, coronary heart disease, dyslipidemia.

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Association of Central Obesity and Waist/Hip Circumference With Dislipidemia

World Nutrition Journal ◽

10.25220/wnj.v01i2.0004 ◽

2018 ◽

Vol 1 (2) ◽

pp. 18

Author(s):

Husnah Husnah

Keyword(s):

Chronic Kidney Disease ◽

Coronary Heart Disease ◽

Risk Factor ◽

Heart Disease ◽

Central Obesity ◽

Spearman Correlation ◽

Hip Circumference ◽

Cross Sectional ◽

Low Hdl ◽

Lipid Metabolic Disorder

Dislipidemia is a lipid metabolic disorder which marked by raised of total cholestrol ratio, LDL, and Trigliserida also reduction HDL ratio. Dislipidemia is risk factor of coronary heart disease, arterio sklerosis, acute miokard infark, Diabetes Melitis, Hipertension, and Chronic Kidney Disease. The aim of this study is knowing the association of central obesity and RLPP with dislipidemia in interna policlinic patient at RSUD Meuraxa. The design of the study is analytic observational with cross sectional approach. Sampling was conduct with purposive sampling with 64 samples. Rate the central obesity and RLPP with measurement while dislipidemia gained from patients registration book formed in laboratorium result. The result was based on age the biggest portion was more than 45 years old (78,1 %) , women more dominant (70,35 %) with central obesity (76,6%) and high RLPP (85,5%). High cholestrol 56,3 %, high LDL 78,1%, high Trigliserida 59,4 and low HDL 62,5%. The result of spearman correlation there was association between of central obesity with dislipidemia P = 0,046 and and RLPP with dislipidemia P = 0.029. We can conclude that there was association between central obesity and RLPP with Dislipidemia.Key words : Dislipidemia, Central Obesity, Waist/Hip Circumference, RLPP

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Alterations of postural and Valsalva responses in coronary heart disease

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1977.233.6.h694 ◽

1977 ◽

Vol 233 (6) ◽

pp. H694-H699 ◽

Cited By ~ 1

Author(s):

F. E. Tristani ◽

D. G. Kamper ◽

D. J. McDermott ◽

B. J. Peters ◽

J. J. Smith

Keyword(s):

Heart Rate ◽

Coronary Heart Disease ◽

Heart Disease ◽

Diastolic Pressure ◽

Valsalva Maneuver ◽

Systolic Pressure ◽

Impedance Method ◽

Normal Male ◽

Control Subjects ◽

Coronary Patients

Patients in congestive heart failure are known to have altered autonomic responses to circulatory stress. In this study, two different age groups of male coronary heart disease (CHD) patients, not in failure, as well as normal male subjects, underwent standard 20-min 70 degrees head-up tilt and Valsalva tests. Responses were monitored by noninvasive methods and cardiac output was estamated with a transthoracic impedance method. During tilt, the CHD patients and control subjects had similar heart rate and diastolic pressure responses. However, the CHD patients had a greater decline in pulse pressure during tilt, mainly due to a decrease in systolic pressure. CHD patients had lesser declines in stroke volume and cardiac index and lesser increases in total vascular resistance than did control subjects. In the Valsalva, the heart rate phase increments (and decrements) from control and rate increments (and decrements) between successive phases were less in the coronary patients. The results indicate that coronary patients, not in failure, have diminished circulatory responses to the tilt and Valsalva maneuver and suggest that these tests may be useful functional indices of cardiovascular capability in coronary disease.

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Dietary intake of Indians living in the metropolitan area of Durban

Public Health Nutrition ◽

10.1017/s1368980099000075 ◽

1999 ◽

Vol 2 (1) ◽

pp. 55-60 ◽

Cited By ~ 9

Author(s):

P Wolmarans ◽

YK Seedat ◽

FGH Mayet ◽

G Joubert ◽

E Wentzel

Keyword(s):

Coronary Heart Disease ◽

Risk Factor ◽

Heart Disease ◽

Energy Intake ◽

Metropolitan Area ◽

Low Density Lipoprotein ◽

Age Groups ◽

Dietary Cholesterol ◽

Density Lipoprotein ◽

Cross Sectional

AbstractObjective:To report on energy and nutrient intakes, as a risk factor for coronary heart disease in Indian South Africans.Design:Cross-sectional dietary study as part of a coronary heart disease survey.Setting:Metropolitan area of Durban, South Africa.Subjects:Free-living Indian men (n = 406) and women (n = 370) 15–69 years of age.Methodology:Dietary data were collected by three interviewers using a 24-h dietary recall and expressed as median intakes of macronutrients.Results:Results reported a low energy intake and the percentage of energy derived from total fat varied between 32.3 and 34.9% in men and between 33.1 and 36.1% in women. The energy intake to basal metabolic rate (EI: BMR) ratios were low for all age groups suggesting potential under-reporting. Intake of polyunsaturated fatty acids was high, more than 10% of energy, with a median polyunsaturated to saturated fatty acid ratio (P: S ratio) that varied between 1.38 and 1.96 for the various age and sex groups. Dietary cholesterol varied between 66 and 117 mg per 4.2 MJ in men and between 76 and 109 mg per 4.2 MJ in women. Dietary fibre intakes were low and varied between 8.0 and 11.0 g per 4.2 MJ in men and between 7.6 and 9.6 g per 4.2 MJ in women.Conclusions:The dietary P:S ratios were high and the effect of such a high P:S ratio on the oxidation of low density lipoprotein in this population, with a high prevalence of coronary heart disease (CHD), should be investigated as a possible risk factor for CHD.

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Korelasi antara Kadar Kolesterol Total dengan Jumlah Monosit pada Pasien Penyakit Jantung Koroner

Berkala Kedokteran ◽

10.20527/jbk.v12i1.361 ◽

2016 ◽

Vol 12 (1) ◽

pp. 95

Author(s):

Fransiska Anggriani Salim ◽

Miftahul Arifin ◽

Asnawati Asnawati

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Total Cholesterol ◽

Causes Of Death ◽

Pearson Correlation ◽

Inclusion Criteria ◽

Cross Sectional ◽

Cholesterol Levels ◽

The World ◽

Pearson Correlation Test

Abstract: Coronary heart disease (CHD) is one of three leading causes of death in the world. CHD is a disease resulting from narrowing or blockage of the arteries that supply blood to the heart muscle. Total cholesterol and monocytes play an important role in the process of atherosclerosis that causes CHD. This study aimed to analyze the correlation between total cholesterol levels and monocytes count in patients with CHD in RSUD Ulin Banjarmasin in August 2014 to May 2015. This study use observational analytic study with cross-sectional approach. 92 samples selected according to the inclusion criteria. The results showed the average of total cholesterol levels and monocytes count are 198.41 mg/dL and 0.58 thousand/uL. The analysis with Pearson correlation test and give a result r=0.033 and p=0.758. The conclusion is there is a very weak, not significant and positive correlation between total cholesterol levels and monocytes count in patients with CHD. Keywords: total cholesterol, monocytes, coronary heart disease Abstrak: Penyakit jantung koroner (PJK) merupakan satu dari tiga penyebab utama kematian di dunia. PJK adalah penyakit yang timbul akibat penyempitan atau penyumbatan arteri yang memasok aliran darah ke otot jantung. Kolesterol total dan monosit berperan penting dalam proses aterosklerosis yang menyebabkan PJK. Penelitian ini bertujuan untuk menganalisis korelasi antara kadar kolesterol total dengan jumlah monosit pada pasien penyakit jantung koroner di RSUD Ulin Banjarmasin periode Agustus 2014-Mei 2015. Penelitian ini adalah penelitian observasional analitik dengan pendekatan cross-sectional. 92 sampel dipilih sesuai kriteria inklusi. Hasil penelitian menunjukkan rata-rata kadar kolesterol total dan jumlah monosit sebesar 198,41 mg/dL dan 0,58 ribu/uL. Kemudian dilakukan análisis dengan uji korelasi Pearson dan didapatkan nilai r=0,033 dan p=0,758. Berdasarkan penelitian yang dilakukan dapat diambil kesimpulan bahwa terdapat korelasi yang sangat lemah, tidak signifikan dan searah antara kadar kolesterol total dengan jumlah monosit pada pasien PJK. Kata-kata kunci: kolesterol total, monosit, penyakit jantung koroner

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Hubungan Kadar Kolesterol Total Dan Hipertensi Dengan Kejadian Penyakit Jantung Koroner DI RSUD dr. Soedarso Pontianak

Jurnal Laboratorium Khatulistiwa ◽

10.30602/jlk.v1i2.144 ◽

2018 ◽

Vol 1 (2) ◽

pp. 99

Author(s):

Laila Kamila ◽

Maulidiyah Salim

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Total Cholesterol ◽

Blood Vessels ◽

Public Hospital ◽

Sampling Technique ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Purposive Sampling

Abstract: Coronary heart is a disease that offense to blood vessels and heart attack due to constriction of blood vessels. A high level of cholesterol in blood or exceeds the normal limit can form sediment in wall of blodd vessels which cause blood vessels constriction or blockage. This research object to determine whether there is a correlation between cholesterol level total and hypertension with coronary heart disease in patients who hospitalized in Regional Public Hospital of dr. Soedarso Pontianak. This study was used cross sectional design, purposive sampling technique, it gained 50 people as samples. The measurement of blood pressure was done in heart poly and cholesterol total level in clinic laboratory of Regional Public Hospital of dr. Soedarso by using enzymatic CHOD-PAP method. It can be obtained that 10 people had hypertension and 40 people did not.the average of total cholesterol was 224 mg/dl. Maximum value of total cholesterol was 224 mg/dl and 152 mg/dl as minimum value. Data has been analyzed by using statistical test, Chi-Square, to determine the correlation of total cholesterol wit coronary heart disease, obtained p value=0,024 (less than α=0,05). Correlation of hypertension and coronary heart disease gained p value=0,923 (more than α=0,05), it can be concluded that total cholesterol correlated with coronary heart disease, and there was not a correlation between hypertension and coronary heart disease.Abstrak: Jantung koroner adalah penyakit yang menyerang pembuluh darah dan serangan jantung, karena penyempitan pada pembuluh darah. Kadar kolesterol yang tinggi dalam darah melebihi normal dapat membentuk endapan pada dinding pembuluh darah sehingga menyebabkan penyempitan dan tersumbatnya pembuluh darah. Penelitian ini bertujuan untuk mengetahui hubungan kadar kolesterol total dan hipertensi dengan penyakit jantung koroner pada pasien di RSUD dr. Soedarso Pontianak. Disain penelitian ini menggunakan cross sectional, teknik pengambilan sampel yaitu purposive sampling, didapat jumlah sampel 50 orang. Pengukuran Tensi Darah dilakukan di poli Jantung dan pemeriksaan kadar kolesterol total di laboratorium klinik RSUD dr. Soedarso Pontianak dengan metode enzimatik CHOD-PAP. Hasil penelitian didapatkan 10 orang mengalami hipertensi dan 40 orang non hipertensi. Rata-rata kadar kolesterol total 224 mg/ dl. Nilai maksimum kadar kolesterol total yaitu 224 mg/dl dan nilai minimum yaitu 152 mg/dl. Analisa data dengan uji statistik Chi-square untuk mengetahui hubungan kolesterol total dengan penyakit jantung koroner didapatkan nilai p = 0,024 (lebih kecil dari α 0,05). Uji hubungan hipertensi dengan penyakit jantung koroner didapat nilai p = 0,923 (lebih besar dari α 0,05), dapat disimpulkan terdapat hubungan kadar kolesterol total dengan penyakit jantung koroner dan tidak ada hubungan hipertensi dengan penyakit jantung koroner.

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