scholarly journals Pathogenesis, Diagnosis and Possible Therapeutic Options for COVID-19

Author(s):  
Md. Asad Ullah ◽  
Yusha Araf ◽  
Bishajit Sarkar ◽  
Abu Tayab Moin ◽  
Riyan Al Islam Reshad ◽  
...  

The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread so rapidly and severely affected the people of almost every country in the world. The highly contagious nature of this virus makes it difficult to take control of the present pandemic situation. With no specific treatment available, the coronavirus disease 2019 (COVID-19) presents a threat to people of all ages including the elderly people and people with other medical complications as a vulnerable group to this disease. Better understanding of viral pathogenesis, appropriate preventive measures, early diagnosis and supportive treatments of the infected patients are now the general solutions to fight against this viral transmission. But, as an emerging disease, most about it remains still poorly understood. This article holds an overview on the origin and structure, pathogenesis, diagnosis and possible therapeutic options for the causative agent, SARS-CoV-2 and disease, COVID-19. However, few therapeutic options, laboratory experiments and other strategies proposed here need to be further clinically tested.

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 171-174
Author(s):  
Tarare Toshida ◽  
Chaple Jagruti

The covid-19 resulted in broad range of spread throughout the world in which India has also became a prey of it and in this situation the means of media is extensively inϑluencing the mentality of the people. Media always played a role of loop between society and sources of information. In this epidemic also media is playing a vital role in shaping the reaction in ϑirst place for both good and ill by providing important facts regarding symptoms of Corona virus, preventive measures against the virus and also how to deal with any suspect of disease to overcome covid-19. On the other hand, there are endless people who spread endless rumours overs social media and are adversely affecting life of people but we always count on media because they provide us with valuable answers to our questions, facts and everything in need. Media always remains on top of the line when it comes to stop the out spread of rumours which are surely dangerous kind of information for society. So on our side we should react fairly and maturely to handle the situation to keep it in the favour of humanity and help government not only to ϑight this pandemic but also the info emic.


Author(s):  
Novita Sari ◽  
M. Saputra ◽  
Aswin Aswin ◽  
Avitha P ◽  
Mega C

Covid-19 merupakan penyakit pernapasan akut yang disebabkan oleh virus corona jenis baru. Penyakit ini pertama kali merebak di Wuhan, Cina lalu menyebar hampir ke seluruh dunia dan menyebabkan pandemi global. Penyakit ini menyerang semua golongan, dewasa, lansia, maupun anak-anak. Semua lapisan masyarakat dari mulai dewasa hingga anak-anak perlu mendapatkan edukasi yang mudah dipahami mengenai Covid19 dan cara-cara pencegahannya. Hal ini yang menjadi dasar dilaksanakannya praktek kerja pengabdian masyarakat IIB Darmajaya. Tujuan kegiatan ini adalah untuk ikut aktif dalam upaya pencegahan virus Covid-19 dengan memberikan sosialisasi tentang Covid-19 dan upaya pencegahannya melalui pembagian APD dan juga pembagian tempat cuci tangan kepada masyarakat Kelurahan Pinang Jaya, Kecamatan Kemiling, Kota Bandar Lampung. Kegiatan ini dilakukan bermitra dengan masyarakat Kelurahan Pinang Jaya . metode yang dipergunakan adalah dengan cara penyuluhan dan sosialisasi tentang pencegahan Covid-19, pengadaan  sarana prasarana pencegahan Covid 19. Hasil dari pengabdian ini adalah masyarakat dapat memahami lebih jauh mengenai virus Covid 19 ini sehingga masyarakat dapat turut serta melakukan upaya pencegahan penularan Covid-19 dimulai dari diri mereka masing-masing. Kata Kunci: Pengabdian, Covid-19, Pandemik, Sosialisasi, Edukasi ABSTRACT Covid-19 is an acute respiratory disease caused by a new type of corona virus. This disease first broke out in Wuhan, China then spread almost throughout the world and caused a global pandemic. This disease attacks all groups, adults, the elderly, and children. All levels of society from adults to children need to get education that is easy to understand about Covid19 and ways to prevent it. This is the basis for implementing IIB Darmajaya community service work practices. The purpose of this activity is to actively participate in efforts to prevent the Covid-19 virus by providing socialization about Covid-19 and prevention efforts through the distribution of PPE and also the distribution of hand washing facilities to the people of Pinang Jaya Village, Kemiling District, Bandar Lampung City. This activity is carried out in partnership with the people of Pinang Jaya Village. The method used is by means of counseling and socialization about the prevention of Covid-19, the provision of infrastructure for preventing Covid-19. of themselves. Keywords: Community Service, Covid-19, Pandemic, Socialization, Education


2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Rajeesh Kumar N.V. ◽  
Arun M. ◽  
Baraneetharan E. ◽  
Stanly Jaya Prakash J. ◽  
Kanchana A. ◽  
...  

Purpose Many investigations are going on in monitoring, contact tracing, predicting and diagnosing the COVID-19 disease and many virologists are urgently seeking to create a vaccine as early as possible. Even though there is no specific treatment for the pandemic disease, the world is now struggling to control the spread by implementing the lockdown worldwide and giving awareness to the people to wear masks and use sanitizers. The new technologies, including the Internet of things (IoT), are gaining global attention towards the increasing technical support in health-care systems, particularly in predicting, detecting, preventing and monitoring of most of the infectious diseases. Similarly, it also helps in fighting against COVID-19 by monitoring, contract tracing and detecting the COVID-19 pandemic by connection with the IoT-based smart solutions. IoT is the interconnected Web of smart devices, sensors, actuators and data, which are collected in the raw form and transmitted through the internet. The purpose of this paper is to propose the concept to detect and monitor the asymptotic patients using IoT-based sensors. Design/methodology/approach In recent days, the surge of the COVID-19 contagion has infected all over the world and it has ruined our day-to-day life. The extraordinary eruption of this pandemic virus placed the World Health Organization (WHO) in a hazardous position. The impact of this contagious virus and scarcity among the people has forced the world to get into complete lockdown, as the number of laboratory-confirmed cases is increasing in millions all over the world as per the records of the government. Findings COVID-19 patients are either symptomatic or asymptotic. Symptomatic patients have symptoms such as fever, cough and difficulty in breathing. But patients are also asymptotic, which is very difficult to detect and monitor by isolating them. Originality/value Asymptotic patients are very hazardous because without knowing that they are infected, they might spread the infection to others, also asymptotic patients might be having very serious lung damage. So, earlier prediction and monitoring of asymptotic patients are mandatory to save their life and prevent them from spreading.


Author(s):  
Garima Kaushik ◽  
Shaney Mantri ◽  
Shrishti Kaushik ◽  
Dhananjay Kalbande ◽  
B. N. Chaudhari

AbstractCOVID-19 has created an interesting discourse among the people of the world particularly regarding preventive measures of infectious diseases. In this paper, the authors forecast the spread of the Coronavirus outbreak and study how the reduction of transmission rates influences its decline. The paper makes use of the SIR (Susceptible Infected Recovered) Model which is a deterministic model used in the field of epidemiology-based on differential equations derived from sections of the population. The Basic Reproduction Number (Ro) represents the criticality of the epidemic in numeric terms. Forecasting an epidemic provides insights about the geographic spreading of the disease and the case incidences required to better inform intervention strategists about situations that may occur during the outbreak. Through this research paper, the authors wish to provide an insight into the impact of control measures on the pandemic. By drawing a comparison of three countries and their quarantine measures, observations on the decline of the outbreak are made. Authors intend to guide the intervention strategies of under-resourced countries like India and aid in the overall containment of the outbreak.


2021 ◽  
Author(s):  
AINUN CAHYA

A sense of nationalism is very important for the young generation of Indonesia to become a developed nation, a modern nation, a safe nation, and a peaceful, just and prosperous nation in the midst of globalization that increasingly challenges the Indonesian state. As a nation and a state in the midst of other nations in the world, a high national identity is needed from its citizens, especially among the young generation of Indonesia. The spirit of nationalism is still needed by the existence of the Indonesian people and the state. High nationalism from citizens or the younger generation will create positive and best behavior for the nation and state. In the current era of globalization, there are factors that cause the waning of the spirit of nationalism among the younger generation. This can be seen from several benchmarks, namely the lack of youth understanding of cultural values. Teenagers are now more likely to follow western culture which is very far in comparison with the norms and customs of the Indonesian nation, The main cause of the fading spirit of nationalism and nationality from the next generation of the nation is mainly due to the wrong and uneducational examples shown by the older generation or the elderly who tend to prioritize interests individuals and groups rather than prioritizing the interests of the nation and the people. This research method uses quantitative methods with data collection using literature studies based on the sources read.


Author(s):  
Inese Stepule

Due to social and economic changes in society, a person's ability to adapt to changing living conditions has diminished. If a person cannot adapt himself, the people around him, especially family members, suffer from this. These sufferings include such shortcomings as violence, trauma, sexual exploitation of children, etc. The study deals with temporary protection against domestic violence. The topic is relevant, since domestic violence is one of the main public health problems. Every year, a large number of people suffer from domestic violence throughout the world. Unfortunately in Latvia compared to other countries of the European Union, domestic violence is a very big problem. Not only women, but also children, the elderly, as well as men, suffer from domestic violence.


Emik ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 144-159
Author(s):  
Astry Ayu Praharsini

In 2020 all countries in the world are busy with a pandemic caused by the Covid-19 Virus. Indonesia is one of the countries whose citizens have been infected with Covid-19 since March 2020 and its spread is fast. Symptoms of being infected with Covid-19 are cough, fever, shortness of breath, anosmia and muscle aches, but in some cases, a person who is exposed to Covid-19 does not even show symptoms at all. Covid-19 can attack various ages ranging from children to the elderly, gender, including pregnant women. Pregnant women are stated to be very vulnerable to contracting Covid-19 with various other diseases, the fear of fetal growth and development cannot be separated from the mother's worries during the Covid-19 pandemic. This article deals with how pregnant women prevent being infected with Covid-19 and how they treat themselves when infected with Covid-19.  This research was conducted in the city of Makassar. The informants involved in this study consisted of 10 pregnant women who are varied on the basis of age (between 19 and 26 years, gestational age (between 12 and 32 weeks) and occupation (seven housewives, a celebgram, a pharmacist, and a nurse). Data was collected usingthe combination of interview and observation. In this study, it was found that the positive impacts of Covid-19 pandemic for pregnant women that their togetherness with members of the family becomes more intensive because they spend more time at home, they are more concerned about personal and family hygiene, they are more physically and mentally healthy, and they become more creative in using their free time. While the negative impact of Covid-19 for pregnant women is that they experience anxiety during the Covid-19 period. However, those who have a better understanding of Covid-19 tend to be positive in dealing with it. Although the efforts made by pregnant women in relation to prevention and treatment are similar but not the same, in preventive efforts, pregnant women are more likely to combine physical activity and various intakes related to efforts to maintain immunity. Meanwhile, in curative efforts, pregnant women limit the duration of physical activity and are more routine in carrying out healing efforts. The difference in nutritional intake also lies in vitamin supplements. In preventive efforts the consumption of supplements is not so ignored and focused on the food consumed, while in a curative effort, they tend to balance food intake and supplements to maintain immunity and accelerate recovery. It is argued in this article that despite the fact pregnant women are vulnerable group, they do not have their own specific treatment either to prevent or to treat them in relation to Covid-19.


2021 ◽  
Vol 14 (2) ◽  
pp. 1-8
Author(s):  
Indranil Chakravorty

India is going through its second surge of COVID-19 pandemic caught off-guard, after it declared rather publicly that India had vanquished the enemy in September 2020. In the last 2 weeks of April 2021, India has beaten several world records for new cases and deaths by official estimates. The real numbers are likely to much higher as the testing and reporting infrastructure remains in shambles. The triple whammy of mass gatherings, lack of administrative and infrastructure preparedness and low vaccination is probably to blame. The humanitarian catastrophe that is played out so visually in heart-wrenching stories across the interconnected digital world is of scrambling for oxygen, scarcity of hospital beds, lack of medication and the incessant burying or cremating of the dead. The desperation in the eyes of the people as they queue outside of locked hospital gates, the oxygen cylinders supplying minutes of life to patients in cars or auto-rickshaws as they wait is heartbreaking. For members of the Indian diaspora, these pictures hurt deep and one is bound to feel helpless. Yet through all this, there is hope. The Gurudwara’s with their oxygen langars, the elderly vacating beds for the younger and often sicker patients, the journalists who are using every social media access to request essential oxygen and drugs, the volunteers who ferry, bury and burn the abandoned dead are testimony of the good that exists in humanity. The world is rising to the call of India including efforts by the Indian diaspora. There are lessons to be learnt but first, let us help and heal.


Author(s):  
Akash Dutt Dubey ◽  
Shreya Tripathi

With almost one third of the world on a lockdown, the corporates and the offices have now rapidly shifted to working from home. Since no specific treatment has been suggested by any medical institution so far, World Health Organization has recommended that the only possible solution to be safe is to self-isolate and stay home. Due to this, the world has come to a screeching halt and the businesses have to be shifted to remote work. Work-from-Home is a very new experience for most of us and hence the perception of the people ranges from being very excited to very hopeless. This study aims to examine the sentiments of the people regarding Work-from-Home concept by analysing twitter activities posted on social media. Total 100,000 tweets were analysed for this study. Results indicate that Work-from-Home concept was taken positively by the people. The emotions associated with most of the tweets were of trust and anticipation indicating that this concept is being welcomed by the people.


Author(s):  
Soumi Banerjee ◽  
Swapnil Shinde ◽  
Anita Patil

Coronavirus has affected China massively. This creates dread among the peoples in the world. Cyber criminals tend to take advantage of fear through malicious activities. Cyber criminals generate a phishing and spam campaign to trick the people in the name of Coronavirus. According to current analysis, the criminals hide malware behind different documents that are shared for creating awareness for the people regarding Coronavirus. Kaspersky technologies discovered that such documents contain viruses, trojans, worms, etc. (malwares) that can infect other files on victims' systems and corrupt or encrypt them. In this chapter, the nature, behavior, and types of different malware and their impacts are analyzed. An analysis is performed on how attackers' attacks using that malware to misuse the victim's data and what the techniques used to perform the attack are. In this chapter, an experimental analysis is performed to detect these attacks, and also measures and guidelines are proposed to prevent these types of attacks.


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