scholarly journals New Intestinal Schistosomiasis Transmission Foci and Soil-transmitted Helminths Infection After Five Years of Preventive Chemotherapy and Associated Risk Factors Among School-aged Children in Two Districts in Southern Ethiopia

Author(s):  
Zerihun Zerdo ◽  
Hilde Bastiaens ◽  
Sibyl Anthierens ◽  
Fekadu Massebo ◽  
Matewos Masne ◽  
...  

Abstract Background: Preventive chemotherapy (PC), is the main elimination strategy against Soil-Tansmitted Helmenthiasis (STH) and Schistosomiasis (SCH) recommended by the world health organization (WHO), should be strengthened through identification of the remaining SCH transmission foci and evaluating its impact to get lesson. This study was aimed to assess the prevalence of STH/SCH infections, intensity of infections and associated factors among School Age Children (SAC) in two districts, previously not known to be endemic for SCH in Southern Ethiopia, October to December 2019.Methods: Structured interview questionnaire was used to collect data, the record of treatment coverage against STH was reviewed and stool samples collected from 2114 children were diagnosed using Kato-Katz technique. Multilevel logistic regressions were used to assess the association of infections with potential predictors. Results: The reviewed treatment coverage ranges from 92% to 106% in both districts. The prevalence of STH infection was 33.3% with 95% confidence interval (CI) of 31.3% to 35.4%. The intensity of infections was light (93.8%, 99.2% & 92.5%), moderate (4.7%, 0.8% & 7.5%) and heavy (1.5%, 0% & 0%) for hookworm, whipworm and Roundworms respectively. STH infection was higher among male SAC with Adjusted Odds Ratio (AOR) of 1.7; 95%CI: 1.4-2.1); occupation of the household head other than farmer or house wife (AOR=0.6; 95%CI: 0.4-0.9) and with higher wealth index (AOR=0.7; 95%CI: 0.5-0.9) as compared to the poorest one. The prevalence of S.mansoni in Dara Mallo district was 34.5% (95%CI: 31.1-38.1%). Light, moderate and heavy S.mansoni infections were 42.9%, 33.7% and 23.4% respectively. Children from mothers aged 50 or above years were significantly more likely infected by S.mansoni (AOR=5.9; 95%CI: 1.4-27.4) as compared to children from mothers (caretakers) of 34 or lower age.Conclusions: Though high PC coverage were reported, STH remained moderately endemic while S.mansoni became moderate endemic in Dara Mallo, requiring sub-district level mapping and deworming campaign initiations. Evidence based strategies which supplement the existing interventions focusing on the identified factors are important to realize the set targets.

2021 ◽  
Vol 42 (2) ◽  
pp. 394-402
Author(s):  
O.B. Aribodor ◽  
C.E. Okaka ◽  
S.O. Sam-Wobo ◽  
B.C. Okpala ◽  
D.N. Aribodor ◽  
...  

Urinary schistosomiasis is considered a major public health parasitic disease in African communities. Prior to this study, Nsugbe community was not considered endemic for the disease and as such was not involved in Praziquantel-Preventive Chemotherapy (PC). Longitudinal study of 281 consented pupils aged 5-16 years was carried out with aim of determining the status of urinary schistosomiasis. Urinalysis laboratory test strip, urine filtration technique and syndromic diagnosis were used for the confirmation of the presence of haematuria in urine samples, identification of Schistosoma haematobium ova and the confirmation of female genital schistosomiasis (FGS), respectively. Risk factors for urinary schistosomiasis infection were determined using pre-tested structured questionnaire. Data were analyzed using Minitab 17 software and intensity of infection categorized following World Health Organization (WHO) recommendations. Of the 281 pupils, 117 (42%) were males and 164 (58%) were females with mean age of 9 years. At baseline, an overall prevalence of 0.4% (1/281) which was of light intensity was established. At follow-up, an overall prevalence of 2.1% (6/281) which was of both light (16.7%) and heavy infection (83.3%) was established. The result of the clinical examination showed eggs of S. haematobium in and around the vaginal area indicating FGS of a female pupil aged 12 years. This was treated. Identified risk factors for S. haematobium infection in the community include water-contact activities, ignorance, source of water supply among others. The study revealed the need for an all inclusive mass administration of Praziquantel-PC in the study community for effective control and possible elimination.


2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Nancy Cruz-Ortiz ◽  
Rodrigo J. Gonzalez ◽  
Kim A. Lindblade ◽  
Frank O. Richards ◽  
Mauricio Sauerbrey ◽  
...  

In Latin America, onchocerciasis is targeted for elimination by 2012 through twice-yearly mass treatment of the eligible population with ivermectin. In Guatemala, two of the four historical endemic foci have demonstrated elimination of transmission, following World Health Organization guidelines. Using established guidelines ophthalmological, serological, and entomological evaluations were conducted in 2007-8 to determine the transmission status of onchocerciasis in the Huehuetenango focus. The prevalence ofOnchocerca volvulusmicrofilariae in the anterior segment of the eye in 365 residents was 0% (95% confidence interval [CI] 0–0.8%), the prevalence of infection ofO. volvulusinSimulium ochraceumamong 8252 flies collected between November 2007 and April 2008 was 0% (95% CI 0–0.02%), and the prevalence of antibodies to a recombinantO. volvulusantigen in 3118 school age children was 0% (95% CI 0–0.1%). These results showed transmission interruption; thus, in 2009 mass treatment was halted and posttreatment surveillance began. To verify for potential recrudescence an entomological evaluation (from December 2010 to April 2011) was conducted during the 2nd and 3rd year of posttreatment surveillance. A total of 4587S. ochraceumwere collected, and the prevalence of infection ofO. volvuluswas 0% (95% CI 0–0.04%). Transmission of onchocerciasis in the Huehuetenango focus has been eliminated.


2019 ◽  
Vol 10 (2) ◽  
pp. 33-36
Author(s):  
Vera L. Gritsinskaya ◽  
Valeria P. Novikova

Anthropometric evaluation is an essential feature of pediatric evaluation. Different countries use different approaches in pediatric growth assessment. The article presents a comparative analysis of the body length (BL) indicators of modern school-age children in St. Petersburg with regional standards (1991) and international standards (WHO Growth Reference 2007). Anthropometric evaluation was conducted among 6207 children aged 7 to 17 years; the median, standard deviation and centile distribution of the BL values of school-age children were determined. We found that the values of BL of modern school-age children are higher than that their peers had thirty years ago; in boys, the maximum difference is found during the pubertal growth spurt; Non-parametric and parametric indicators of BL in senior pupils of St. Petersburg are higher than in the standards of the World Health Organization; in junior schoolchildren no difference was found. The data we obtained create the prerequisites for the development of modern regional standards for growth assessment of children and school-age children in St. Petersburg and their practical use for pediatric examinations.


2021 ◽  
Vol 15 (5) ◽  
pp. e0009444
Author(s):  
Ryan E. Wiegand ◽  
W. Evan Secor ◽  
Fiona M. Fleming ◽  
Michael D. French ◽  
Charles H. King ◽  
...  

Background World Health Organization (WHO) guidelines for measuring global progress in schistosomiasis control classify individuals with Schistosoma spp. infections based on the concentration of excreted eggs. We assessed the associations between WHO infection intensity categories and morbidity prevalence for selected S. haematobium and S. mansoni morbidities in school-age children. Methodology A total of 22,488 children aged 6–15 years from monitoring and evaluation cohorts in Burkina Faso, Mali, Niger, Uganda, Tanzania, and Zambia from 2003–2008 were analyzed using Bayesian logistic regression. Models were utilized to evaluate associations between intensity categories and the prevalence of any urinary bladder lesion, any upper urinary tract lesion, microhematuria, and pain while urinating (for S. haematobium) and irregular hepatic ultrasound image pattern (C-F), enlarged portal vein, laboratory-confirmed diarrhea, and self-reported diarrhea (for S. mansoni) across participants with infection and morbidity data. Principal findings S. haematobium infection intensity categories possessed consistent morbidity prevalence across surveys for multiple morbidities and participants with light infections had elevated morbidity levels, compared to negative participants. Conversely, S. mansoni infection intensity categories lacked association with prevalence of the morbidity measures assessed. Conclusions/significance Current status infection intensity categories for S. haematobium were associated with morbidity levels in school-age children, suggesting urogenital schistosomiasis morbidity can be predicted by an individual’s intensity category. Conversely, S. mansoni infection intensity categories were not consistently indicative of childhood morbidity at baseline or during the first two years of a preventive chemotherapy control program.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yilma Chisha ◽  
Zerihun Zerdo ◽  
Mekuria Asnakew ◽  
Chuchu Churko ◽  
Manaye Yihune ◽  
...  

Abstract Background World Health Organization estimated that 779 million people are at risk of getting schistosomiasis (SCH) and 240 million people were infected worldwide. SCH due to Schistosoma mansoni (S. mansoni) is a wide public health problem in Ethiopia. The aim of the survey was to quantify national and district disaggregated treatment coverage status for SCH and compare validated coverage with the one reported. Methods Community based cross-sectional survey was conducted in April 2019 among households with school age children (SAC) 5–14 years in seven purposively selected districts of the country. Segments to be surveyed were randomly selected and households to be interviewed from each segment were determined using systematic sampling technique. A total of 3378 households visited and 5679 SAC (5–14 years) were interviewed. Results Overall reported treatment coverage of Praziquantel (PZQ) against SCH was 4286 (75.5%). Males were 27% more likely to swallow the drug (AOR = 1.27; 95% CI: 1.09, 1.47) than females. SAC with age 10–14 years were 45% more likely to swallow the drug compared with their counter parts (5–9 years), (AOR =1.45; 95% CI: 1.25, 1.69). There is statistically significant association between PZQ swallowing status with school enrollment. (AOR = 20.90, 95% CI: 17.41, 25.08). Swallowing status of PZQ against SCH significantly higher for SAC treated in districts applied integrated treatment approach (87.5%) compared with SAC treated in vertical treatment approach (72.5%); P-value < 0.001. SACs were asked for reasons for not taking the drug and the main reported reason for not swallowing PZQ in the present study was none attending of the school. Conclusions Over all treatment coverage of PZQ against SCH in the present study was 75.5%. Although it is in accordance with WHO recommendation for Ethiopia, national programmatic improvements are necessary to achieve higher coverage in the future. To increase treatment coverage for PZQ against SCH in Ethiopia, school based training should target all schools. Moreover, mobilization, sensitization and implementation of the community wide treatment need to be improved.


2017 ◽  
Vol 1 (2) ◽  
pp. 308 ◽  
Author(s):  
Christoph Lange ◽  
Anna M. Mandalakas ◽  
Barbara Kalsdorf ◽  
Claudia M. Denkinger ◽  
Martina Sester

Despite global efforts to control tuberculosis (TB) the estimated number of people who developed TB worldwide increased to an all-time record of more than 10 million in 2015. The goal of the World Health Organization (WHO) to reduce the global incidence of TB to less than 100 cases per million by 2035, cannot be reached unless TB prevention is markedly improved. There is a need for an improved vaccine that better protects individuals who are exposed to Mycobacterium tuberculosis from infection and active disease compared to the current M. bovis Bacille Calmette Guérin (BCG) vaccine. In the absence of such a vaccine, prevention relies on infection control measures and preventive chemotherapy for people with latent infection with M. tuberculosis (LTBI), who have the highest risk of progression to active TB. During the past decade, interferon-γ release assays (IGRAs) have increasingly replaced the tuberculin skin test as screening tools for the diagnosis of LTBI in countries with a low incidence of TB. Despite recent WHO guidelines on the management of LTBI, the definition of groups at risk for TB remains controversial, and the role of IGRAs for TB prevention in low-incidence countries remains uncertain. We reviewed the scientific literature and provide recommendations for the use of IGRAs for LTBI diagnosis in low-incidence countries. These recommendations are based on the number of patients needing treatment in order to prevent one case of TB. As the positive predictive value of IGRAs for the development of TB is sub-optimal, research must focus on the identification of alternative biomarkers that offer better predictive ability in order to substantially reduce the number needing treatment while improving the prevention of TB and improving the effectiveness of targeted preventive chemotherapy.


2021 ◽  
Vol 9 (T4) ◽  
pp. 212-217
Author(s):  
Mundakir Mundakir ◽  
Asri Asri ◽  
SG Winata

BACKGROUND: Tuberculosis (TB) is major community health problem in Indonesia. The World Health Organization report in 2017 shows that 6.4 million new TB cases were officially notified to national authorities, worldwide. Indonesia has 842,0000 cases and places it as the country with the third highest number in the world. The national program Directly Observed treatment, short-course started since 2014 has not able to handle TB cases comprehensively. Communities have important role in TB management. AIM: The aim of this study was to explore the existed condition of TB management and control. METHODS: A descriptive qualitative study was conducted in Tandes Sub-district, which is an endemic area for TB and has the highest incident in Surabaya. Semi-structured interview was conducted to 13 participants who consist of sub-urban TB task force, community health volunteer, Community Health Nurses, and sub-district officer. RESULTS: Result reveal six themes: Altruism as intentional caring factor, in adequate number of staff, the need to improve training skill, insufficient of resources, limited of financial support, and social support. CONCLUSION: To be effective program, community-based TB management need to be improve in the availability of budget, staff, training, and resources while maintaining the ongoing work of TB task force team. Community-based TB program is one of the activities whose efficiency was reliable for handling TB.


2021 ◽  
Vol 16 (2) ◽  
Author(s):  
Maria Paola Maurelli ◽  
Paola Pepe ◽  
Antonio Montresor ◽  
Denise Mupfasoni ◽  
Martina Nocerino ◽  
...  

Soil-transmitted helminth (STH) infections are among the most common neglected tropical diseases worldwide causing high morbidity and mortality rates in endemic areas. Preventive chemotherapy (PC) programmes and health education are recommended by the World Health Organization (WHO) to reduce the impact of STH in endemic countries. Following our role as WHO collaborating centre (WHO CC ITA-116), we have developed a WebGIS and a dataset to support PC programmes to monitor the impact of STH control. This vHealth presentation shows the potentiality of these tools in improving communication among WHO’s regional and country offices, Ministries of Health, pharmaceutical industries and other partners.


Partner Abuse ◽  
2021 ◽  
pp. PA-D-20-00006
Author(s):  
Naeem Akram

Domestic violence exists in every country, irrespective of the culture, ethnicity, age, income, and education of the women. World Health Organization (WHO) has estimated that approximately 35% of women worldwide had experienced sexual or physical violence. The present study has attempted to analyze the role of different socioeconomic indicators on the prevalence of domestic violence. In this regard, data of Pakistan Demographic and Health Survey (PDHS) 2017–2018 has been used and logit models have been estimated. It has been found that women married below the age of 18; living in rural areas; have more children; whose mothers experienced violence; feared their husbands; with little to or no autonomy in decision-making; had a bank account; married outside of the family; and had not inherited any land or property were significantly more vulnerable victims of domestic violence. It has been found that women’s education, education of her husband, and exposure to media by creating awareness may protect women from domestic violence. Furthermore, working women are more likely to face domestic violence, but women who have started working before marriage are significantly less vulnerable victims of domestic violence. However, the age of women herself, the age of husband, age of household head and wealth of household, living in the nucleus or joint family, receiving any support from Benazir Income Support Program (BISP) have no significant role in determining the domestic violence in Pakistan.


2010 ◽  
Vol 4 (4) ◽  
pp. 1894
Author(s):  
Eliana Peres Rocha ◽  
Maria José Clapis ◽  
Christianne Alves Pereira Calheiros

ABSTRACTObjective: to identify the profile of nursing professionals providing care to pregnant women in maternity Alfenas-MG. Method: this is about a descriptive cross sectional study from quantitative approach. All nursing professionals (24) who worked in the care of patients participated in this study. Data collection was performed during the period from June to September 2008 using a structured interview. This study was conducted according to ethical principles of research and approved by the Ethics in Research of Universidade Federal de Alfenas/MG, under protocol number3087.001016/2008-98. Results: there was a lack of midwife in the team, keeping workload of 49.17 hours/week, 91.6% being female. As the professional category, the prevailing mid-level professionals with informal training and monitoring at work those with greater experience in the area. Conclusion it is understood that these professionals are not qualified for the obstetric care according to criteria of World Health Organization (WHO), highlighting the need for qualification of this team that assists women in maternity Alfenas, Minas Gerais. Descriptors: nursing; obstetric nursing; delivery; professional competence; qualified attention. RESUMOObjetivo: identificar o perfil dos profissionais de enfermagem que atendem as parturientes em maternidades de Alfenas-MG. Método: estudo descritivo de corte transversal com abordagem metodológica quantitativa. Participaram deste estudo todos os profissionais de enfermagem (24) que atuam na assistência às parturientes. A coleta de dados foi realizada no período de junho a setembro de 2008, utilizando-se um roteiro de entrevista. Este estudo foi conduzido segundo os preceitos éticos da pesquisa e aprovado pelo Comitê de Ética em Pesquisa da Universidade Federal de Alfenas/MG, sob o protocolo nº 23087.001016/2008-98. Resultados: verificou-se a ausência de enfermeira obstétrica na equipe, mantendo carga horária de trabalho de 49,17 horas/semana, sendo 91,6 % do sexo feminino . Quanto à categoria profissional, prevalecem os profissionais de nível médio com treinamento informal e acompanhamento durante o trabalho; os quais possuem maior experiência na área. Conclusão entende-se que esses profissionais não estão qualificados para o atendimento obstétrico segundo os critérios da Organização Mundial de Saúde (OMS), evidenciando-se a necessidade de qualificação dessa equipe que atende as mulheres nas maternidades de Alfenas, Minas Gerais. Descritores: enfermagem; enfermagem obstétrica; parto; competência profissional; equipe de enfermagem.RESUMENObjetivo: identificar el perfil de los profesionales de enfermería que atienden a mujeres embarazadas en la maternidad Alfenas-MG. Método: estudio descriptivo transversal de enfoque cuantitativo. Participaron en este estudio, todos los profesionales de enfermería (24) que trabajan en el cuidado de los pacientes. Los datos fueron recolectados durante el período de junio a septiembre de 2008 utilizando una entrevista estructurada. Este estudio se realizó de acuerdo con los principios éticos de la investigación y aprobado por la Ética en la Investigación de la Universidad Federal de Alfenas - MG, en el marco del Protocolo 23087.001016/2008-98. Resultados Hubo una falta de matrona en el equipo, manteniendo la carga de trabajo de 49,17 horas a la semana, el 91,6% de ser mujer. A medida que la categoría profesional, la vigente de nivel medio profesionales con la formación informal y la supervisión en el trabajo, quienes tienen mayor experiencia en el área. Conclusión: se entiende que estos profesionales no están calificados para la atención obstétrica de acuerdo con los criterios de la Organización Mundial de la Salud (OMS), destacando la necesidad de calificación de este equipo que ayuda a las mujeres en la maternidad Alfenas, Minas Gerais. Descriptores: enfermería; enfermería obstétrica; entrega; competencia profesional. 


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