scholarly journals Caste-specific gut symbionts contribute to the different adult longevity in the honeybee

2020 ◽  
Author(s):  
Hongfang Wang ◽  
Baohua Xu
Keyword(s):  
Nervous System ◽  
Immune Regulation ◽  
Agricultural Production ◽  
Endocrine System ◽  
Adult Longevity ◽  
Biological Models ◽  
Gut Symbionts ◽  
Queen Bees ◽  
Honeybee Health ◽  
The Relationship

Abstract Background Honeybees are important pollinators, and their health is important to agricultural production and ecosystem. Queen-bees contain same genome as worker-bees, but live longer and healthier than worker-bees; thus, queen and worker pairs are natural biological models for studying longevity. Concerns are increasing regarding the relationship between gut microbes and honeybee health. We compared the hindgut microflora of queen and worker (Apis mellifera carpatica) by sequencing the bacterial 16S DNA, then salvaging the caste-specific microbes using LEfSe analysis and predicting the microbial functions using Tax4Fun, hoping to find potential gut symbionts associated with longevity. Results The hindgut microflora of queens differed from those of worker. Queens had higher abundances of Commensalibacter, Lactobacillus and Bifidobacterium than workers. The dominant microflora in the worker hindguts were Gilliamella (29.37%), Lactobacillus (15.28%), Commensalibacter (13.65%), Snodgrassella (11.56%), Bifidobacterium (6.07%) and Frischella (3.51%). The dominant microflora in the queen hindguts were Commensalibacter (44.89%), Lactobacillus (38.42%), Bifidobacterium (6.74%), Gilliamella (2.44%) and Bombella (2.41%). Queen-specific microbes was Bombella genus, and worker-specific microbes included Snodgrassella alvi, Frischella perrara and Gilliamella apicola. Queen and worker hindgut microbes exhibited diverse functions in lipid metabolism, neurodegenerative diseases, endocrine system, nervous system and immune system; those functions were linked to honeybee fitness and longevity. The queen-specific symbiont, Bombella, was predicted to be involved in host endocrine and immune regulation, which may contribute to queens living longer and healthier than worker bees. Conclusion The supernal Acetobacteraceae (especially Commensalibacter and Bombella), Lactobacillus and Bifidobacterium in the queen-hindgut help the queen bees live longer and healthier than the worker bees. This study may help determine the mechanisms of queen longevity and enable further understanding the positive roles of gut symbionts in honeybee fitness.

scholarly journals Chronic Intestinal Pseudo-Obstruction: Is There a Connection with Gut Microbiota?

2021 ◽  
Vol 9 (12) ◽  
pp. 2549
Author(s):  
Giulia Radocchia ◽  
Bruna Neroni ◽  
Massimiliano Marazzato ◽  
Elena Capuzzo ◽  
Simone Zuccari ◽  
...  
Keyword(s):  
Nervous System ◽  
Treatment Strategies ◽  
Endocrine System ◽  
Clinical Syndrome ◽  
Intestinal Lumen ◽  
Significant Challenge ◽  
Severe Impairment ◽  
Intestinal Pseudo Obstruction ◽  
The Relationship

Chronic intestinal pseudo-obstruction (CIPO) is a rare clinical syndrome characterized by severe impairment of gastrointestinal (GI) motility, and its symptoms are suggestive of partial or complete intestinal obstruction in the absence of any lesion restricting the intestinal lumen. Diagnosis and therapy of CIPO patients still represent a significant challenge for clinicians, despite their efforts to improve diagnostic workup and treatment strategies for this disease. The purpose of this review is to better understand what is currently known about the relationship between CIPO patients and intestinal microbiota, with a focus on the role of the enteric nervous system (ENS) and the intestinal endocrine system (IES) in intestinal motility, underling the importance of further studies to deeply understand the causes of gut motility dysfunction in these patients.

scholarly journals Immunity – a Significant Pathogenic Factor as Well as an Integral Part of the Psychoneuroendocrine-Immune Regulations

2018 ◽  
pp. 165-173
Author(s):  
F. Vožeh
Keyword(s):  
Nervous System ◽  
Immune System ◽  
Immune Regulation ◽  
Endocrine System ◽  
Short Review ◽  
The Body ◽  
Pathogenic Factor ◽  
Essential Factor ◽  
Detailed Understanding ◽  
Health And Disease

Immunity plays an important role in the reactivity of the organism and, in this context, is an essential factor in the pathogenesis of many diseases. Basically, there is no system or organ in the body, whose dysfunction is not related to immunity consequences. In addition, there are also multisystem diseases simultaneously involving multiple body systems. They are not always caused by weak immunity, but also often by modified immune reactions known as overshooting. The essence of all these diseases is a change in the reactivity of the organism where immunity plays an important role. The immunity as such is then part of the systems of neuroendocrine-immune regulation, which have common mediators and receptors. The establishment of psychoneuroimmunology, a relatively new discipline in neuroscience, contributed to a detailed understanding of these mechanisms between central and peripheral nervous system, the endocrine system and the immune system. This research enabled the uncovering of the nature of stress-diseases and impact of other regulatory disturbances on the function of various body organs and systems of the organism as a whole. The aim of this short review is to show complex interconnections of these relationships to better understand the human health and disease.

Postsynaptic neuronal geometry and synaptic effectiveness

1987 ◽  
Vol 45 ◽  
pp. 690-697
Author(s):  
C.J. Wilson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Synaptic Function ◽  
Postsynaptic Neuron ◽  
Synaptic Inputs ◽  
Partial Analysis ◽  
Postsynaptic Cell ◽  
Neuronal Geometry ◽  
The Relationship ◽  
Complex Scale

Most central nervous system neurons receive synaptic input from hundreds or thousands of other neurons, and the computational function of such neurons results from the interactions of inputs on a large and complex scale. In most situations that have yielded to a partial analysis, the synaptic inputs to a neuron are not alike in function, but rather belong to distinct categories that differ qualitatively in the nature of their effect on the postsynaptic cell, and quantitatively in the strength of their influence. Many factors have been demonstrated to contribute to synaptic function, but one of the simplest and best known of these is the geometry of the postsynaptic neuron. The fundamental nature of the relationship between neuronal shape and synaptic effectiveness was established on theoretical grounds prior to its experimental verification.

Risk assessment of occupational and occupationally conditioned diseases connection to noise when exceeding maximum permissible levels

2019 ◽  
pp. 17-19
Author(s):  
Vladimir A. Fokin ◽  
Dmitrii M. Shlyapnikov ◽  
Svetlana V. Red’ko
Keyword(s):  
Blood Pressure ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
High Blood Pressure ◽  
Noise Exposure ◽  
Physical Factors ◽  
Autonomic Nervous ◽  
Permissible Levels ◽  
The Relationship ◽  
Perm Region

In accordance with the requirements of paragraph 3.2.6 of sanitary rules and norms «Sanitary and epidemiological requirements for physical factors at workplace», in the event of exceeding noise level at workplace above 80 dBA, an employer is obliged to assess the health risk of workers and confirm an acceptable risk to their health. The connection between the incidence of occupational and occupationally conditioned diseases with noise exposure exceeding the maximum permissible levels (80 dBA) was estimated. The assessment was carried out at a food industry enterprise of Perm Region. Assessing the relationship between morbidity and noise exposure is the first step in evaluation of occupational health risks for workers exposed to noise exceeding MAL. If a reliable relationship between morbidity and noise exposure is established, an assessment of occupational risk is conducted. The odds ratio (OR) for diseases characterized by high blood pressure and disorders of autonomic nervous system was <1 (confidence interval CI=0.11–1.61 and CI=0.08–2.78, respectively). The relative risk (RR) for diseases characterized by high blood pressure and disorders of autonomic nervous system was <1. The received data testify absence of connection of morbidity with exposure to industrial noise, calculation of etiological share of responses and levels of risk is not required.

The Relationship between the Development of Human Capital and the Agricultural Economy in Rural Areas

2020 ◽  
pp. 61-65
Author(s):  
B.A. Voronin ◽  
◽  
I.P. Chupina ◽  
Ya.V. Voronina ◽  
◽  
...  
Keyword(s):  
Human Capital ◽  
Rural Areas ◽  
Agricultural Production ◽  
Agricultural Sector ◽  
Real Life ◽  
Standard View ◽  
Household Factors ◽  
Economic Transformations ◽  
The Relationship

The article discusses a non-standard view of the formation of human capital for work in organizations of the agricultural sector of the economy, in the context of modern socio-economic transformations. In the classical sense, human capital for agriculture should be formed and developed in rural areas. But in real life, this is not always the case, because there are many factors that prevent the classical solution of this problem. First, the demographic factor affects, second, social and household factors, and third, in many rural areas there are no working agricultural organizations where qualified agricultural specialists can work. All these and other circumstances actualize the problem of the quality of human capital in rural areas in relation to the development of agricultural production.

Population - an element of agricultural development in Serbia

Stanovnistvo ◽  
1999 ◽  
Vol 37 (1-4) ◽  
pp. 141-161
Author(s):  
Marina Todorovic ◽  
Gordana Vojkovic
Keyword(s):  
Agricultural Production ◽  
Regional Differences ◽  
Agricultural Development ◽  
Historical Review ◽  
Working Population ◽  
Theoretical Level ◽  
Level Of Education ◽  
Agricultural Producer ◽  
The Impact ◽  
The Relationship

The author begins by discussing the relationship between agriculture and population at a theoretical level, proceeds with a historical review of changes in the role and significance of an individual as agricultural producer, and finally, analyzes population as an element (potentials - limitations) of agricultural development in Serbia. The overall production results, and particularly the propensity to technical and technological innovation, as well as the ability to adapt to the changed conditions are, as we know well, crucially dependent on the structure of the working population. Hence, the author discusses regional differences in agricultural population by age, sex, level of education and productivity to provide a clear illustration of the impact of this element (indicator) on the population as the factor of agricultural production. The results show significant macroregional differences by this element with respect to the average for Serbia.

New concepts on the structure of the neuronal networks: The miniaturization and hierarchical organization of the central nervous system*

1984 ◽  
Vol 4 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Luigi F. Agnati ◽  
Kjell Fuxe
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuronal Networks ◽  
Hierarchical Organization ◽  
Memory Storage ◽  
Information Handling ◽  
New Concepts ◽  
The Central Nervous System ◽  
Local Circuits ◽  
The Relationship

The hypothesis is introduced that miniaturization of neuronal circuits in the central nervous system and the hierarchical organization of the various levels, where information handling can take place, may be the key to understand the enormous capability of the human brain to store engrams as well as its astonishing capacity to reconstruct and organize engrams and thus to perform highly sophisticated integrations. The concept is also proposed that in order to understand the relationship between the structural and functional plasticity of the central nervous system it is necessary to postulate the existence of memory storage at the network level, at the local circuit level, at the synaptic level, at the membrane level, and finally at the molecular level. Thus, memory organization is similar to the hierarchical organization of the various levels, where information handling takes place in the nervous system. In addition, each higher level plays a role in the reconstruction and organization of the engrams stored at lower levels. Thus, the trace of the functionally stored memory (i.e. its reconstruction and organization at various levels of storage) will depend not only on the chemicophysical changes in the membranes of the local circuits but also on the organization of the local circuits themselves and their associated neuronal networks.

scholarly journals Eco-Efficiency and Human Capital Efficiency: Example of Small- and Medium-Sized Family Farms in Selected European Countries

2021 ◽  
Vol 13 (12) ◽  
pp. 6846
Author(s):  
Jan Polcyn
Keyword(s):  
Human Capital ◽  
Agricultural Production ◽  
Efficiency Index ◽  
European Countries ◽  
Family Farms ◽  
Work Hour ◽  
Capital Efficiency ◽  
Environmental Measures ◽  
The Relationship ◽  
Economic Measure

Small- and medium-sized family farms are places to live and sources of income for about half of the population. The aim of this analysis was to determine the relationship between eco-efficiency and human capital efficiency on small- and medium-sized family farms. The analysis was carried out using an economic measure (value of agricultural production per work hour calculated per hectare) and two synthetic measures (human capital and environmental measures). The synthetic measures were determined using the TOPSIS-CRITIC method by defining weights for variables used in the measures. The analysis covered five countries: Lithuania (960 farms), Moldavia (532 farms), Poland (696 farms), Romania (872 farms) and Serbia (524 farms). All of these countries are characterised by a high fragmentation of agricultural holdings. The analysis allowed us to formulate the following conclusions: eco-efficiency and human capital efficiency indices increased with area for small- and medium-sized family farms. An increase in the eco-efficiency index with an increase in farm area suggests that the smaller the farm area, the more extensive the agricultural production that was carried out. In addition, an increase in human capital efficiency with an increase in farm area indicates that there was inefficiency in the utilisation of human capital resources on the agricultural farms studied.

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