scholarly journals Mood Symptoms and Other Maternal Factors in Pregnancy and Adverse Neonate Outcomes

2020 ◽  
Author(s):  
Hua Li ◽  
Angela Bowen ◽  
Rudy Bowen ◽  
Nazeem Muhajarine ◽  
Lloyd Balbuena

Abstract Background Antenatal women experience a higher level of mood symptoms, which have negative effects on mothers’ mental and physical health and their newborns. The relation of maternal moods including depression and anxiety and other maternal factors in pregnancy and neonate outcomes are well-studied with inconsistent findings. Although antenatal women experience a higher level of mood instability (MI), the association between antenatal MI and neonatal outcomes has not been investigated. We aimed to address this gap and to contribute to the pregnancy-neonate outcomes literature by examining the relationship between antenatal mood symptoms and other maternal factors and neonatal outcomes.Methods A prospective cohort of women (n = 555) participated in this study at early pregnancy (T1, 17.4 ± 4.9 weeks) and late pregnancy (T2, 30.6 ± 2.7 weeks). The Edinburgh Postnatal Depression Scale (EPDS) was used to assess antenatal depressive symptoms, the EPDS anxiety subscale was utilized to measure anxiety symptoms, and mood instability was measured using a visual analogue scale. These mood states together with stress, social support, as well as healthy and unhealthy behaviours were also examined in relation to neonatal outcomes using chi-square tests and logistic regression models. Results Depression and MI were unrelated to adverse neonatal outcomes and anxiety was related to Apgar score with marginal statistical significance. Higher stress, lack of partner support, smoking, and primiparous status were associated with some adverse outcomes.Conclusions The current study identified no associations between antenatal mood symptoms and neonatal outcomes. Our findings further support and extend previous evidence on smoking abstinence or cessation, and the provision of resources for stress management and social support that could help prevent or alleviate adverse neonatal outcomes.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hua Li ◽  
Angela Bowen ◽  
Rudy Bowen ◽  
Nazeem Muhajarine ◽  
Lloyd Balbuena

Abstract Background Antenatal women experience an increased level of mood and anxiety symptoms, which have negative effects on mothers’ mental and physical health as well as the health of their newborns. The relation of maternal depression and anxiety in pregnancy with neonate outcomes is well-studied with inconsistent findings. However, the association between antenatal mood instability (MI) and neonatal outcomes has not been investigated even though antenatal women experience an elevated level of MI. We sought to address this gap and to contribute to the literature about pregnancy neonate outcomes by examining the relationship among antenatal MI, depression, and anxiety and neonatal outcomes. Methods A prospective cohort of women (n = 555) participated in this study at early pregnancy (T1, 17.4 ± 4.9 weeks) and late pregnancy (T2, 30.6 ± 2.7 weeks). The Edinburgh Postnatal Depression Scale (EPDS) was used to assess antenatal depressive symptoms, anxiety was measured by the EPDS anxiety subscale, and mood instability was measured by a visual analogue scale with five questions. These mood states together with stress, social support, as well as lifestyle were also examined in relation to neonatal outcomes using chi-square tests and logistic regression models. Results Mood instability, depression, and anxiety were unrelated to adverse neonatal outcomes. Only primiparous status was associated with small for gestational age after Bonferroni correction. Conclusions We report no associations between antenatal mood symptoms including MI, depression, and anxiety and neonatal outcomes. More studies are required to further explore the relationship between antenatal mood instability, depression, and anxiety and neonatal outcomes.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Despina Pampaka ◽  
Stefania I. Papatheodorou ◽  
Mohammad AlSeaidan ◽  
Rihab Al Wotayan ◽  
Rosalind J. Wright ◽  
...  

Abstract Background The association of antenatal depression with adverse pregnancy, birth, and postnatal outcomes has been an item of scientific interest over the last decades. However, the evidence that exists is controversial or limited. We previously found that one in five women in Kuwait experience antenatal depressive symptoms. Therefore, the aim of this study was to examine whether antenatal depressive symptoms are associated with preterm birth (PTB), small for gestational age (SGA), or large for gestational age (LGA) babies in this population. Methods This was a secondary analysis based on data collected in the Transgenerational Assessment of Children’s Environmental Risk (TRACER) Study that was conducted in Kuwait. Logistic regression analysis was used to examine whether antenatal depressive symptoms assessed using the Edinburgh Depression Scale (EDS) were associated with preterm birth, small for gestational age, and large for gestational age babies. Results A total of 1694 women had complete information about the outcomes of interest. Women with depressive symptoms in pregnancy had increased, albeit non-significant, odds of having PTB (OR = 1.41; 95%CI: 0.81, 2.45), SGA babies (OR = 1.26; 0.80, 1.98), or LGA babies (OR = 1.27; 0.90, 1.79). Antenatal depressive symptoms had similar increased odds for the three outcomes even after adjusting for several covariates though none of these reached statistical significance. Conclusions In the present study, the depressive symptoms in pregnancy did not predict adverse birth outcomes, such as PTB, SGA, and LGA, which adds to the currently non-conclusive literature. However, further research is needed to examine these associations, as the available evidence is quite limited.


Author(s):  
Fatemeh Sadat Asgarian ◽  
Ali Keyhani ◽  
Abdorreza Naser Moghadasi ◽  
Mohammad Ali Sahraian ◽  
Farnaz Etesam

Background: Considering the high probability of suicidal behaviors in multiple sclerosis (MS) population of other countries and the unlikeliness of its diagnosis in patients with MS by specialists, the current research targets the frequency of suicidal thoughts and mood symptoms in a group of patients with MS in Iran. Also, we investigated the relationships among suicidal thoughts, anxiety, depression, anticipated stigma, social support, some disease characteristics, and sociodemographic factors. Methods: A sample of 276 subjects were selected from community-based MS clinics and referral out-patient MS clinic of Sina Hospital affiliated to Tehran University of Medical Sciences, Tehran, Iran. Participants completed the Patient Health Questionnaire (PHQ), the Hospital Anxiety and Depression Scale (HADS), the Chronic Illness Anticipated Stigma Scale (CIASS), the Multidimensional Scale of Perceived Social Support (MSPSS), and a personal information questionnaire. Results: 36.2% of the participants had suicidal thoughts. Suicidal ideation was significantly more likely among people who reported higher anxiety and depression scores or anticipated stigma from their friends and families. Women and patients with higher education experienced suicidal ideation more frequently than others. Conclusion: Findings regarding the comorbidity of suicidal thoughts with anticipated stigma, depression and anxiety in MS patients emphasizes therapeutic interventions focused on the alleviation of perceived stigma as well as mood symptoms.


SLEEP ◽  
2017 ◽  
Vol 40 (suppl_1) ◽  
pp. A177-A177 ◽  
Author(s):  
G Bourjeily ◽  
V Danilack ◽  
M Bublitz ◽  
H Lipkind ◽  
D Caldwell ◽  
...  

2015 ◽  
Vol 11 (5) ◽  
pp. 1376-1384 ◽  
Author(s):  
Deborah Da Costa ◽  
Phyllis Zelkowitz ◽  
Kaberi Dasgupta ◽  
Maida Sewitch ◽  
Ilka Lowensteyn ◽  
...  

This cross-sectional study aims to determine the prevalence and determinants of depressive symptoms in first-time expectant fathers during their partner’s third trimester of pregnancy. As part of a prospective study examining depressive symptoms in men over the first postnatal year, 622 men (mean age = 34.3 years, ±5.0 years) completed standardized online self-report questionnaires measuring depressed mood, physical activity, sleep quality, social support, marital adjustment, life events, financial stress, and demographics during their partner’s third trimester of pregnancy. The Edinburgh Depression Scale was used to assess depressed mood. Partners also completed the Edinburgh Depression Scale in the third trimester. The results revealed that 13.3% of expectant fathers exhibited elevated levels of depressive symptoms during their partner’s third trimester of pregnancy. Significant independent factors associated with antenatal depressive symptoms in men were poorer sleep quality, family history of psychological difficulties, lower perceived social support, poorer marital satisfaction, more stressful life events in the preceding 6 months, greater number of financial stressors, and elevated maternal antenatal depressive symptoms. These findings highlight the importance of including fathers in the screening and early prevention efforts targeting depression during the transition to parenthood, which to date have largely focused only on women. Strategies to promote better sleep, manage stress, and mobilize social support may be important areas to address in interventions tailored to new fathers at risk for depression during the transition to parenthood.


2016 ◽  
Vol 47 (4) ◽  
pp. 766-775 ◽  
Author(s):  
V. Senturk ◽  
M. Abas ◽  
M. Dewey ◽  
O. Berksun ◽  
R. Stewart

BackgroundIn a perinatal cohort of women in urban and rural Turkey, we investigated associations between antenatal depressive symptoms and subsequent changes in perceived quality of key family relationships.MethodOf 730 women recruited in their third trimester (94.6% participation), 578 (79.2%) were reassessed at a mean of 4.1 (s.d. = 3.3) months after childbirth, 488 (66.8%) were reassessed at 13.7 (s.d. = 2.9) months, and 448 (61.4%) at 20.8 (s.d. = 2.7) months. At all four examinations, self-reported quality of relationship with the husband, mother and mother-in-law was ascertained using the Close Persons Questionnaire with respect to emotional support, practical support and negative aspects of the relationship. Antenatal depressive symptoms were defined using the Edinburgh Postnatal Depression Scale. A range of covariates in mixed models was considered including age, education, number of children, family structure, physical health, past emotional problems and stressful life events.ResultsKey findings were as follows: (i) reported emotional and practical support from all three relationships declined over time in the cohort overall; (ii) reported emotional support from the husband, and emotional and practical support from the mother-in-law, declined more strongly in women with antenatal depressive symptoms; (iii) associations between depressive symptoms and worsening spouse relationship were more pronounced in traditional compared with nuclear families.ConclusionsAntenatal depressive symptoms predicted marked decline in the quality of key relationships over the postnatal period. This may account for some of the contemporaneous associations between depression and worse social support, and may compound the risk of perinatal depression in subsequent pregnancies.


2018 ◽  
Vol 131 ◽  
pp. 160S-161S
Author(s):  
Malini D. Persad ◽  
Victoria Ly ◽  
Kimberly Herrera ◽  
Michael Demishev ◽  
J. Gerald Quirk ◽  
...  

Author(s):  
Dongning He ◽  
Jianhua Ren ◽  
Biru Luo ◽  
Jie Xiang ◽  
Guoyu Wang ◽  
...  

Abstract Objective: The study aims to investigate women’s psychological health, family function, and social support during the third trimester within the COVID-19 epidemic. Method: From January 30, 2020 to February 26, 2020, 177 pregnant women during their third trimester (mean gestation time was 37.05±4.06 weeks) in a maternal and children’s hospital were investigated using the Self-Rating Anxiety Scale (SAS), the Edinburgh Postnatal Depression Scale, the Family APGAR Index, and the Perceived Social Support Scale. Non-parametric tests were conducted in the study. The statistical significance was set as p < 0.05. Result: The incidence rate of the participants’ anxiety and depression during the COVID-19 epidemic was 19.21% and 24.29%, respectively. The participants’ greatest concerns in the previous week were the risk of virus transmission (79.66%), and the prenatal examination and fetal growth (70.62%). The SAS ranks were higher in the participants who were concerned about the prenatal examination and fetal growth and work-related affairs. Conclusion: The participants’ psychological health was indirectly affected by the epidemic through the supply of medical resources and work-related factors. The medical staff should employ family support and social resources to guarantee the accessibility of medical services and living materials to decrease the pregnant women’s stress and further improve their psychological health.


2020 ◽  
Author(s):  
Samuel Ginja ◽  
Katherine Jackson ◽  
James J Newham ◽  
Emily J Henderson ◽  
Debbie Smart ◽  
...  

Abstract Background: International data suggest that living in a rural area is associated with an increased risk of perinatal mental illness. This study tested the association between rurality and risk for two mental illnesses prevalent in perinatal women - depression and anxiety.Methods: Using a cross-sectional design, antenatal and postnatal women were approached by healthcare professionals and through other networks in a county in Northern England (UK). After providing informed consent, women completed a questionnaire where they indicated their postcode (used to determine rural-urban status) and completed three outcome measures: the Edinburgh Postnatal Depression Scale (EPDS), the Whooley (depression measure), and the Generalised Anxiety Disorder 2-item (GAD-2). Logistic regression models were developed, both unadjusted and adjusted for potential confounders, including socioeconomic status, social support and perinatal stage.Results: 295 participants provided valid data. Women in rural areas (n=130) were mostly comparable to their urban counterparts (n=165). Risk for depression and/or anxiety was found to be higher in the rural group across all models: unadjusted OR 1.67 95% CI 1.03 to 2.72, p=.038. This difference though indicative did not reach statistical significance after adjusting for socioeconomic status and perinatal stage (OR 1.57 (0.40), 95% CI 0.95 to 2.58, p=.078), and for social support (OR 1.65 (0.46), 95% CI 0.96 to 2.84, p=.070).Conclusions: Data suggested that women in rural areas were at higher risk of depression and anxiety than their urban counterparts. Further work should be undertaken to corroborate these findings and investigate the underlying factors. This will help inform future interventions and the allocation of perinatal services to where they are most needed.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 295-295
Author(s):  
Sunghwan Cho ◽  
Kyuhyung Chung

Abstract Depression increases suicidal risk lowers quality of life in older adults. However, it is unknown how loneliness and depression are associated with young-old and old-older adults. This study examined association of loneliness and depression from the National Social Life, Health, and Aging Project (NSHAP) (2015-2016), estimating moderating effects of social support. The sample of this study was community dwelling Medicare beneficiaries aged 65+ (n=1,532): young-older adults (n=903) and old-older adults (n=629). Loneliness was measured by the Revised University of California, Los Angeles Loneliness Scale short form (3 items; young, M=.86, SD=.73; old, M=.87, SD=.67; range 0-3). Social support consists of two variables each measured by 4 items, spouse/partner support (young, M=2.29, SD=.50; old, M=2.26, SD=.51; range 0-3) and family support (young-old, M=2.19, SD=.52; old-old, M=2.23, SD=.52; range 0-3). Depression was measured by Center for Epidemiological Studies Depression scale (11 items, young, M=1.41, SD=.42; old, M=1.45, SD=.42; range 1-4). Multiple linear regression was used in this study, including relevant covariates. Findings indicated loneliness in both groups (young, p&lt;.001; old, p&lt;.001), spouse support in both groups (young, p&lt;.001; old, p&lt;.001) had statistical significance in depression. Family support in young-older adults (p&lt;.05) had a statistical significance for depression. Interaction of loneliness and spouse support moderated the relationship between loneliness and depression in old-older adults (p&lt;.05). Findings suggest old-older adults’ loneliness and depression could be soothed by spousal support. Spousal support could be important in that the informal caregiver is likely to focus on older adults with fragility at the end of their lives.


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