scholarly journals Cancer and industrial activities in China

2021 ◽  
Author(s):  
Xuemei Zhang ◽  
Haitao Yin ◽  
Jay Shimshack
Keyword(s):  
Value Added ◽  
Cancer Registries ◽  
Environmental Drivers ◽  
County Level ◽  
Lung Cancers ◽  
Incidence And Mortality ◽  
Cancer Cluster ◽  
Cancer Clusters ◽  
Adjusted Incidence ◽  
The Village

Abstract Associations between pollution and life expectancy, infant mortality, and cardiorespiratory disease are documented in China. Yet, less is known about environmental drivers of Chinese cancers. Here, we systematically link polluting industrial activity to cancer incidence, cancer mortality, and cancer cluster designations. We investigate county-level associations between industrial production and age-adjusted incidence and mortality reported in official cancer registries. We then combine the locations of roughly 3 million enterprises with administrative data from roughly 600,000 villages and cancer cluster documentation from 380 villages. We show that county-level value-added from industry is associated with age-adjusted incidence and mortality for all cancers; bronchus, trachea, and lung cancers; stomach cancers; and esophageal cancers. We show that the odds that a village contains a documented cancer cluster increase 3-4 times if the village contains a pollution-intensive industrial facility. Leather, chemical, and dye enterprises appear to drive results. All else equal, smaller facilities increase the odds of cancer clusters.

Trends in the incidence and mortality of oral cancer in Nevada (Preprint)

2020 ◽  
Author(s):  
Kevin Foote ◽  
Karl Kingsley
Keyword(s):  
Public Health ◽  
Oral Cancer ◽  
Cancer Incidence ◽  
Cancer Control ◽  
Cancer Registries ◽  
Public Health Research ◽  
Chi Square ◽  
Incidence And Mortality ◽  
The Us ◽  
Chi Square Analysis

BACKGROUND Reviews of national and state-specific cancer registries have revealed differences in rates of oral cancer incidence and mortality that have implications for public health research and policy. Many significant associations between head and neck (oral) cancers and major risk factors, such as cigarette usage, may be influenced by public health policy such as smoking restrictions and bans – including the Nevada Clean Indoor Act of 2006 (and subsequent modification in 2011). OBJECTIVE Although evaluation of general and regional advances in public policy have been previously evaluated, no recent studies have focused specifically on the changes to the epidemiology of oral cancer incidence and mortality in Nevada. METHODS Cancer incidence and mortality rate data were obtained from the National Cancer Institute (NCI) Division of Cancer Control and Population Sciences (DCCPS) Surveillance, Epidemiology and End Results (SEER) program. Most recently available rate changes in cancer incidence and mortality for Nevada included the years 2012 – 2016 and are age-adjusted to the year 2000 standard US population. Comparisons of any differences between Nevada and the overall US population were evaluated using Chi square analysis. RESULTS This analysis revealed that the overall rates of incidence and mortality from oral cancer in Nevada differs from that observed in the overall US population. For example, although the incidence of oral cancer among Caucasians is increasing in Nevada and the US overall, it is increasing at nearly twice that rate in Nevada, P=0.0002. In addition, although oral cancer incidence among Minorities in the US is declining, it is increasing in Nevada , P=0.0001. Analysis of reported mortality causes revealed that mortality from oral cancer increased in the US overall but declined in Nevada during the same period (2012-2016). More specifically, mortality among both Males and Females in the US is increasing, but is declining in Nevada, P=0.0027. CONCLUSIONS Analysis of the epidemiologic data from Nevada compared with the overall US revealed significant differences in rates of oral cancer incidence and mortality. More specifically, oral cancer incidence increased in Nevada between 2012-2016 among all groups analyzed (Males, Females, White, Minority), while decreases were observed nationally among Females and Minorities. Although mortality in Nevada decreased over this same time period (in contrast to the national trends), the lag time between diagnosis (incidence) and mortality suggests that these trends will change in the near future. CLINICALTRIAL Not applicable

scholarly journals Global Burden, Risk Factors, and Trends of Esophageal Cancer: An Analysis of Cancer Registries from 48 Countries

Cancers ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 141
Author(s):  
Junjie Huang ◽  
Anastasios Koulaouzidis ◽  
Wojciech Marlicz ◽  
Veeleah Lok ◽  
Cedric Chu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Cancer ◽  
The Netherlands ◽  
Cancer Registries ◽  
Global Burden ◽  
Annual Percent Change ◽  
The United Kingdom ◽  
Incidence And Mortality ◽  
Elevated Cholesterol ◽  
Prevalence Of Obesity

This study aimed to examine the global burden, risk factors, and trends of esophageal cancer based on age, sex, and histological subtype. The data were retrieved from cancer registries database from 48 countries in the period 1980–2017. Temporal patterns of incidence and mortality were evaluated by average annual percent change (AAPC) using joinpoint regression. Associations with risk factors were examined by linear regression. The highest incidence of esophageal cancer was observed in Eastern Asia. The highest incidence of adenocarcinoma (AC) was found in the Netherlands, the United Kingdom, and Ireland. A higher AC/squamous cell carcinoma (SCC) incidence ratio was associated with a higher prevalence of obesity and elevated cholesterol. We observed an incidence increase (including AC and SCC) in some countries, with the Czech Republic (female: AAPC 4.66), Spain (female: 3.41), Norway (male: 3.10), Japan (female: 2.18), Thailand (male: 2.17), the Netherlands (male: 2.11; female: 1.88), and Canada (male: 1.51) showing the most significant increase. Countries with increasing mortality included Thailand (male: 5.24), Austria (female: 3.67), Latvia (male: 2.33), and Portugal (male: 1.12). Although the incidence of esophageal cancer showed an overall decreasing trend, an increasing trend was observed in some countries with high AC/SCC incidence ratios. More preventive measures are needed for these countries.

scholarly journals Food Environments and Hepatocellular Carcinoma Incidence

2021 ◽  
Vol 18 (11) ◽  
pp. 5740
Author(s):  
Mimi Ton ◽  
Michael J. Widener ◽  
Peter James ◽  
Trang VoPham
Keyword(s):  
Hepatocellular Carcinoma ◽  
Food Environment ◽  
Variance Estimation ◽  
Cancer Registries ◽  
County Level ◽  
Individual Level ◽  
Retail Food Environment ◽  
Food Retailers ◽  
Environment Index ◽  
Rate Ratios

Research into the potential impact of the food environment on liver cancer incidence has been limited, though there is evidence showing that specific foods and nutrients may be potential risk or preventive factors. Data on hepatocellular carcinoma (HCC) cases were obtained from the Surveillance, Epidemiology, and End Results (SEER) cancer registries. The county-level food environment was assessed using the Modified Retail Food Environment Index (mRFEI), a continuous score that measures the number of healthy and less healthy food retailers within counties. Poisson regression with robust variance estimation was used to calculate incidence rate ratios (IRRs) and 95% confidence intervals (CIs) for the association between mRFEI scores and HCC risk, adjusting for individual- and county-level factors. The county-level food environment was not associated with HCC risk after adjustment for individual-level age at diagnosis, sex, race/ethnicity, year, and SEER registry and county-level measures for health conditions, lifestyle factors, and socioeconomic status (adjusted IRR: 0.99, 95% CI: 0.96, 1.01). The county-level food environment, measured using mRFEI scores, was not associated with HCC risk.

scholarly journals Incidence and mortality of ischemic stroke subtypes in Joinville, Brazil: a population-based study

2015 ◽  
Vol 73 (8) ◽  
pp. 648-654 ◽  
Author(s):  
Marcos C. Lange ◽  
Norberto L. Cabral ◽  
Carla H. C. Moro ◽  
Alexandre L. Longo ◽  
Anderson R. Gonçalves ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Population Based ◽  
Large Artery ◽  
Vessel Occlusion ◽  
Population Based Study ◽  
Incidence And Mortality ◽  
One Year ◽  
Undetermined Etiology ◽  
And Control ◽  
Adjusted Incidence

Aims To measure the incidence and mortality rates of ischemic stroke (IS) subtypes in Joinville, Brazil. Methods All first-ever IS patients that occurred in Joinville from January 2005 to December 2006 were identified. The IS subtypes were classified by the TOAST criteria, and the patients were followed-up for one year after IS onset. Results The age-adjusted incidence per 100,000 inhabitants was 26 (17-39) for large-artery atherosclerosis (LAA), 17 (11-27) for cardioembolic (CE), 29 (20-41) for small vessel occlusion (SVO), 2 (0.6-7) for stroke of other determined etiology (OTH) and 30 (20-43) for stroke of undetermined etiology (UND). The 1-year mortality rate per 100,000 inhabitants was 5 (2-11) for LAA, 6 (3-13) for CE, 1 (0.1-6) for SVO, 0.2 (0-0.9) for OTH and 9 (4-17) for UND. Conclusion In the population of Joinville, the incidences of IS subtypes were similar to those found in other populations. These findings highlight the importance of better detection and control of atherosclerotic risk factors.

scholarly journals Incidence and Mortality Patterns of Acute Myeloid Leukemia in Belgrade, Serbia (1999–2013)

Medicina ◽  
2018 ◽  
Vol 54 (1) ◽  
pp. 5 ◽  
Author(s):  
Natasa Maksimovic ◽  
Milica Zaric ◽  
Tatjana Gazibara ◽  
Goran Trajkovic ◽  
Gorica Maric ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Population Analysis ◽  
Age Groups ◽  
Mortality Rates ◽  
Single Digit ◽  
Age Cohorts ◽  
Incidence And Mortality ◽  
Adjusted Incidence ◽  
Acute Myeloid

Introduction: To assess incidence and mortality trends of acute myeloid leukemia (AML) in Belgrade (Serbia) in a 15-year period (from 1999 to 2013). Material and Methods: Data were obtained from the Cancer Registry of Serbia, Institute of Public Health of Serbia. Standardized incidence and mortality rates per 100,000 inhabitants were calculated by direct standardization method using World Standard Population. Analysis of raw data indicated single-digit numbers per year and per 5-year age cohorts. Therefore, we merged years of diagnosis to three-year intervals, creating so-called “moving averages”. We also merged study population to 10-year age cohorts. Results: Both incidence and mortality rates increased with age, i.e., the lowest rates were observed in the youngest age groups and the highest rates were observed in oldest age groups. In all age groups, except the youngest (15–24 years), AML incidence was statistically significantly higher in men compared with women. Average age-adjusted incidence was 2.73/100,000 (95% confidence interval (CI) 2.28–3.71). Average age-adjusted mortality was 1.81/100,000 (95% CI 1.30–2.26). Overall, there were no significant changes in incidence trend. Age-adjusted incidence rates had increasing tendency among men aged 65–74 years (B = 0.80, standard error (SE) = 0.11; p = 0.005) and in total population aged 65–74 years (B = 0.41, SE = 0.09; p = 0.023). Increasing tendency in incidence of AML among women was observed in age group >75 years (B = 0.63, SE = 0.14; p = 0.019). No changes of mortality trend were observed. Conclusion: There was no significant change in trends of AML from 1999 to 2013 in the population of Belgrade.

Cancer incidence and mortality trends from 2003 to 2014 in Italy

2019 ◽  
Vol 105 (2) ◽  
pp. 121-137 ◽  
Author(s):  
Carlotta Buzzoni ◽  
Emanuele Crocetti ◽  
Stefano Guzzinati ◽  
Luigino Dal Maso ◽  
Silvia Francisci ◽  
...  
Keyword(s):  
Cancer Incidence ◽  
Cancer Registries ◽  
Cancer Site ◽  
Prevention Measures ◽  
The South ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Incidence And Mortality ◽  
Study Results ◽  
Incident Cases

Objective: To evaluate short-term (2003–2014) cancer incidence and mortality trends in Italy. Methods: Italian Cancer Registries data, available in the AIRTUM database, from 17 out of 20 regions were used. The number of incident cases and deaths were estimated for those registries and those years with incomplete information. Age-standardized rates, overall and stratified by geographic area, region, sex, cancer site, and major age group, were computed. Time trends were expressed as annual percent change of rates. Results: In Italy, among males, incidence rates for all cancers showed during 2003–2014, a significant decrease (−0.9%/year), with stronger reductions in the northwest (−1.3%/year) and northeast (−2.0%/year since 2006) than in central (−0.7%/year) and southern (−0.4%/year) areas. Among females, a weak but significant overall reduction was detected (−0.1%/year), with a stronger decrease in the northwest (−0.5%/year). Incidence increased among women in the south (0.3%/year) of Italy. Mortality decreased in both sexes (−1.0%/year among males and −0.5%/year among females), but not in the south, where rates had a stable tendency. Conclusions: Incidence among males decreased, supported by trends for prostate, lung, colorectal, and urinary bladder cancers; among females the. The overall cancer incidence trend was stable, or even decreasing, in the northern and central areas and increasing in the southern areas, due to lung, thyroid, and melanoma rising trends. Study results provided information on the outcomes, in terms of cancer incidence and mortality, of primary and secondary prevention measures employed by regional health systems.

Epidemiology of Childhood Cancer in Piemonte and Valle d'Aosta during 1965-69.

1975 ◽  
Vol 61 (3) ◽  
pp. 291-304 ◽  
Author(s):  
Guido Pastore ◽  
Benedetto Terracini
Keyword(s):  
Age Groups ◽  
Soft Tissue Sarcomas ◽  
Cancer Registries ◽  
Mortality Rates ◽  
Number Of Children ◽  
Incidence And Mortality ◽  
The Central Nervous System ◽  
The Difference ◽  
Hodgkin's Lymphomas ◽  
The U.S

Piemonte and Valle d'Aosta are in the NW part of Italy. In 1967 total population and population aged 0-14 were respectively 4.338.000 and 841.000. During the period 1965-69 a total of 688 cases of cancer (including leukemia) were diagnosed in children under 15 years of age resident in this area. The Cancer Registry of Piedmont and Valle d'Aosta (RTP) provided information on 465 children; the other 223 were collected through additional investigation in the files of 31 university or hospital departments of the region and 5 extraregional hospitals. Distribution through the 5 years covered by the investigation is shown in Table 1. Histological or hematological confirmation of the diagnosis was available in 499 cases (73%). The 688 cases included 216 leukemias, 131 tumors of the central nervous system, 40 neuroblastomas, 82 lymphomas (including 34 cases of Hodgkin's disease), 46 nephroblastomas, 32 soft-tissue sarcomas, 29 bone sarcomas (including 5 cases of Ewing's disease), 25 retinoblastomas, 12 thyroid tumors, 10 extragenital teratomas, 5 ovarian dysgerminomas, 4 tumours of the testes, 4 hepatoblastomas and 52 other tumours (Table 2). The number of children under 15 years of age dying of cancer during 1965-69 was 341 (Table 2). Incidence and mortality rates by age groups are given in Tables 3 and 4. The rates were of the same order as those observed in the U.S. and in other European cancer registries during the same period (Tables 4, 5 and 6). The mortality rate for nephroblastomas at age 0-4 was 1,09/100.000/year, i.e. slightly higher than that observed in the U.S. in 1960 but about twice as high as that observed in the U.S. in 1967 (14). Incidence and mortality rates for both Hodgkin's and non-Hodgkin's lymphomas were about 3 times higher in males than in females (Table 3). The difference was less obvious during the first five years of life, in which the total number of diagnosed lymphomas was 16.

TWENTY-TWO YEARS OF CANCER CLUSTER INVESTIGATIONS AT THE CENTERS FOR DISEASE CONTROL

1990 ◽  
Vol 132 (supp1) ◽  
pp. 43-47 ◽  
Author(s):  
GLYN G. CALDWELL
Keyword(s):  
New York ◽  
Disease Control ◽  
Local Health ◽  
Local Health Departments ◽  
Laboratory Methods ◽  
The Public ◽  
Foreign Countries ◽  
Cancer Cluster ◽  
Cancer Clusters ◽  
Centers For Disease Control

Abstract Beginning in 1961, the Centers for Disease Control investigated 108 cancer clusters and reported the findings in Epidemic Aid Reports. The clusters studied were of leukemia (38%), leukemia and lymphoma (30%), leukemia and other cancer combinations (13%), and all other cancer or combinations (19%). These clusters occurred in 29 states and five foreign countries, with the largest numbers from Connecticut (11), California (eight), Illinois (eight), New York (eight), Georgia (seven), Pennsylvania (six), and Iowa (five). All other states reported less than five. Eight different data collection methods were used, often in combinations, and four types of laboratory methods on four different specimen types. Although 14 different categories of associations were reported, no dear cause was found for any cluster. Nonetheless, concern about clusters by the public and media, and the need to investigate them, warrants the development of a uniform approach for use by local health departments.

scholarly journals Cancer cure for 32 cancer types: results from the EUROCARE-5 study

2020 ◽  
Vol 49 (5) ◽  
pp. 1517-1525
Author(s):  
Luigino Dal Maso ◽  
Chiara Panato ◽  
Andrea Tavilla ◽  
Stefano Guzzinati ◽  
Diego Serraino ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Relative Survival ◽  
Cancer Registries ◽  
Population Based ◽  
Lung Cancers ◽  
Pancreatic Cancers ◽  
Corpus Uteri ◽  
Cure Fraction ◽  
Prostate Cancers

Abstract Background Few studies have estimated the probability of being cured for cancer patients. This study aims to estimate population-based indicators of cancer cure in Europe by type, sex, age and period. Methods 7.2 million cancer patients (42 population-based cancer registries in 17 European countries) diagnosed at ages 15–74 years in 1990–2007 with follow-up to 2008 were selected from the EUROCARE-5 dataset. Mixture-cure models were used to estimate: (i) life expectancy of fatal cases (LEF); (ii) cure fraction (CF) as proportion of patients with same death rates as the general population; (iii) time to cure (TTC) as time to reach 5-year conditional relative survival (CRS) >95%. Results LEF ranged from 10 years for chronic lymphocytic leukaemia patients to <6 months for those with liver, pancreas, brain, gallbladder and lung cancers. It was 7.7 years for patients with prostate cancer at age 65–74 years and >5 years for women with breast cancer. The CF was 94% for testis, 87% for thyroid cancer in women and 70% in men, 86% for skin melanoma in women and 76% in men, 66% for breast, 63% for prostate and <10% for liver, lung and pancreatic cancers. TTC was <5 years for testis and thyroid cancer patients diagnosed below age 55 years, and <10 years for stomach, colorectal, corpus uteri and melanoma patients of all ages. For breast and prostate cancers, a small excess (CRS < 95%) remained for at least 15 years. Conclusions Estimates from this analysis should help to reduce unneeded medicalization and costs. They represent an opportunity to improve patients’ quality of life.

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