scholarly journals Antiviral Effects of Gelatin Stabilized Ferrous Sulfide Nanoparticles

2021 ◽  
Author(s):  
Ting Tong ◽  
Shuangfei Deng ◽  
Xiaotong Zhang ◽  
Liurong Fang ◽  
Jiangong Liang ◽  
...  
Keyword(s):  
Environmental Remediation ◽  
Low Cost ◽  
Antiviral Effect ◽  
High Reactivity ◽  
Host Cells ◽  
Antiviral Effects ◽  
Ferrous Sulfide ◽  
Effective Inhibition ◽  
Co Precipitation ◽  
First Time

Abstract Ferrous sulfide nanoparticles (FeS NPs) are widely applied to environmental remediation, catalysis, energy storage and medicine because of their high reactivity, large specific surface area and low cost, arousing great interest of researchers. However, there is no literature reported on its application in the antiviral field. In the study, gelatin stabilized FeS nanoparticles (Gel-FeS NPs) were synthesized by co-precipitation of Fe2+ and S2‒ in the aqueous phase with continuous stirring under anaerobic conditions. The as-prepared Gel-FeS NPs were good stabilization and dispersibility with the size distribution of 77.7 ± 16.4 nm, as determined by UV-Vis spectrometer, TEM, FTIR, XRD and XPS. We reported for the first time the virucidic and antiviral activity of Gel-FeS NPs. The Gel-FeS NPs with good dispersibility and biocompatibility were synthesized, and they exhibited effective inhibition on the proliferation of PRRSV by blocking the PRRSV outside the host cells. Moreover, the Fe2+ from degraded ferrous sulfide still displayed an antiviral effect, demonstrating the advantage as an antiviral nanomaterial of Gel-FeS NPs compared to other nanomaterials. This work highlighted the antiviral effect of Gel-FeS NPs, broaden the applications of iron-based nanoparticles for combating the virus.

Chemical and Antiviral Study on Alkaloids from Papaver pseudocanescens M. Pop.

2012 ◽  
Vol 67 (1-2) ◽  
pp. 22-28 ◽  
Author(s):  
Ralitsa Istatkova ◽  
Lubomira Nikolaeva-Glomb ◽  
Angel Galabov ◽  
Gerelt-Od Yadamsuren ◽  
Javzan Samdan ◽  
...  
Keyword(s):  
Biological Activities ◽  
Antiviral Effect ◽  
Human Pathogens ◽  
Aerial Parts ◽  
Antiviral Effects ◽  
Benzylisoquinoline Alkaloid ◽  
Phytochemical Investigation ◽  
Taxonomic Groups ◽  
First Time

The phytochemical investigation of the aerial parts of Papaver pseudocanescens M. Pop. of Mongolian origin resulted in the isolation and structural elucidation of 8 alkaloids of the isoquinoline and promorphinane type. 8,14-Dihydroamurine, 8,14-dihydroflavinantine, and flavinantine are promorphinanes. Alborine, mecambridine, and mecambridine methohydroxide are retroprotoberberines. Amurensinine is an isopavine alkaloid and O-methylarmepavine is a benzylisoquinoline alkaloid. O-Methylarmepavine is a new alkaloid for the genus Papaver. Promorphinane-type alkaloids have been found for the first time in the species. All structures were established by physical and spectral analysis. As a first attempt to describe some of the biological activities of these alkaloids, the antiviral effect was tested against the in vitro replication of several viruses which belong to different taxonomic groups and represent significant human pathogens. Based on the results, the conclusion could be drawn that particular alkaloids from P. pseudocanescens possess selective antiviral effects against the replication of poliovirus 1 and human rhinovirus 14, two viruses from the Enterovirus genus of the Picornaviridae family.

Electrospun TiO2 embedded nanofibers for photocatalytic applications

2019 ◽  
Vol 34 (01n03) ◽  
pp. 2040015
Author(s):  
Junyao Wu ◽  
Alexandre Pernin ◽  
Yixuan Wang ◽  
Han Wang ◽  
Jun Yao ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Photocatalytic Activity ◽  
Environmental Remediation ◽  
Low Cost ◽  
High Reactivity ◽  
Simulated Sunlight ◽  
Electrospinning Technique ◽  
Sunlight Irradiation ◽  
Text Content ◽  
Photocatalytic Applications

The development of photocatalysts with low cost, high reactivity and easy recovery provides great potentials for environmental remediation. In this study, polyacrylonitrile (PAN) nanofibers containing titanium dioxide ([Formula: see text]) nanoparticles were successfully fabricated using a facile electrospinning technique. The effects of [Formula: see text] content, PAN concentration and thermal treatment on the adsorption and photocatalysis properties of [Formula: see text] nanofibers have been investigated. The results indicate that the embedded [Formula: see text] nanofibers possess the property to effectively decompose rhodamine B (RhB) under simulated sunlight irradiation. The enhanced photocatalytic activity can be attributed to the loading of [Formula: see text] nanoparticles and the property of polymer matrix.

scholarly journals Controllable growth of three-dimensional CdS nanoparticles on TiO2 nanotubes to enhance photocatalytic activity

RSC Advances ◽  
2020 ◽  
Vol 10 (28) ◽  
pp. 16776-16782 ◽  
Author(s):  
Guo-Min Liu ◽  
Wen-Yuan Jia ◽  
Qiu-Shi Jiang ◽  
Zhi-Qiang Cheng
Keyword(s):  
Photocatalytic Activity ◽  
Energy Conversion ◽  
Environmental Remediation ◽  
Tio2 Nanotubes ◽  
Low Cost ◽  
Three Dimensional ◽  
High Reactivity ◽  
Cds Nanoparticles ◽  
Controllable Growth

Exploiting photocatalysts with characteristics of low cost, high reactivity and good circularity is a great significance for environmental remediation and energy conversion.

Iridium-Catalyzed Silylation of C-H bonds in Unactivated Arenes: A Sterically-Encumbered Phenanthroline Ligand Accelerates Catalysis Enabling New Reactivity

2019 ◽  
Author(s):  
Caleb Karmel ◽  
Zhewei Chen ◽  
John Hartwig
Keyword(s):  
High Activity ◽  
Functional Group ◽  
Activity Analysis ◽  
High Reactivity ◽  
High Yield ◽  
Phen Ligand ◽  
Mechanistic Studies ◽  
Phenanthroline Ligand ◽  
First Time ◽  
New System

We report a new system for the silylation of aryl C-H bonds. The combination of [Ir(cod)(OMe)]<sub>2</sub> and 2,9-Me<sub>2</sub>-phenanthroline (2,9-Me<sub>2</sub>phen) catalyzes the silylation of arenes at lower temperatures and with faster rates than those reported previously, when the hydrogen byproduct is removed, and with high functional group tolerance and regioselectivity. Inhibition of reactions by the H<sub>2</sub> byproduct is shown to limit the silylation of aryl C-H bonds in the presence of the most active catalysts, thereby masking their high activity. Analysis of initial rates uncovered the high reactivity of the catalyst containing the sterically hindered 2,9-Me<sub>2</sub>phen ligand but accompanying rapid inhibition by hydrogen. With this catalyst, under a flow of nitrogen to remove hydrogen, electron-rich arenes, including those containing sensitive functional groups, undergo silylation in high yield for the first time, and arenes that underwent silylation with prior catalysts react over much shorter times with lower catalyst loadings. The synthetic value of this methodology is demonstrated by the preparation of key intermediates in the synthesis of medicinally important compounds in concise sequences comprising silylation and functionalization. Mechanistic studies demonstrate that the cleavage of the aryl C-H bond is reversible and that the higher rates observed with the 2,9-Me<sub>2</sub>phen ligand is due to a more thermodynamically favorable oxidative addition of aryl C-H bonds.

scholarly journals UV Inscription and Pressure Induced Long-Period Gratings through 3D Printed Amplitude Masks

Sensors ◽  
2021 ◽  
Vol 21 (6) ◽  
pp. 1977
Author(s):  
Ricardo Oliveira ◽  
Liliana M. Sousa ◽  
Ana M. Rocha ◽  
Rogério Nogueira ◽  
Lúcia Bilro
Keyword(s):  
State Of The Art ◽  
Low Cost ◽  
Resonance Wavelength ◽  
Complex Structures ◽  
Pressing Method ◽  
Long Period ◽  
Long Period Gratings ◽  
3D Printed ◽  
Mechanical Pressing ◽  
First Time

In this work, we demonstrate for the first time the capability to inscribe long-period gratings (LPGs) with UV radiation using simple and low cost amplitude masks fabricated with a consumer grade 3D printer. The spectrum obtained for a grating with 690 µm period and 38 mm length presented good quality, showing sharp resonances (i.e., 3 dB bandwidth < 3 nm), low out-of-band loss (~0.2 dB), and dip losses up to 18 dB. Furthermore, the capability to select the resonance wavelength has been demonstrated using different amplitude mask periods. The customization of the masks makes it possible to fabricate gratings with complex structures. Additionally, the simplicity in 3D printing an amplitude mask solves the problem of the lack of amplitude masks on the market and avoids the use of high resolution motorized stages, as is the case of the point-by-point technique. Finally, the 3D printed masks were also used to induce LPGs using the mechanical pressing method. Due to the better resolution of these masks compared to ones described on the state of the art, we were able to induce gratings with higher quality, such as low out-of-band loss (0.6 dB), reduced spectral ripples, and narrow bandwidths (~3 nm).

scholarly journals A Microcosm Treatability Study for Evaluating Wood Mulch-Based Amendments as Electron Donors for Trichloroethene (TCE) Reductive Dechlorination

Water ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 1949
Author(s):  
Edoardo Masut ◽  
Alessandro Battaglia ◽  
Luca Ferioli ◽  
Anna Legnani ◽  
Carolina Cruz Viggi ◽  
...  
Keyword(s):  
Electron Donor ◽  
Environmental Sustainability ◽  
Reductive Dechlorination ◽  
Environmental Remediation ◽  
Low Cost ◽  
Chlorinated Solvents ◽  
Electron Donors ◽  
Chlorinated Ethenes ◽  
Dehalococcoides Mccartyi ◽  
Wood Mulch

In this study, wood mulch-based amendments were tested in a bench-scale microcosm experiment in order to assess the treatability of saturated soils and groundwater from an industrial site contaminated by chlorinated ethenes. Wood mulch was tested alone as the only electron donor in order to assess its potential for stimulating the biological reductive dechlorination. It was also tested in combination with millimetric iron filings in order to assess the ability of the additive to accelerate/improve the bioremediation process. The efficacy of the selected amendments was compared with that of unamended control microcosms. The results demonstrated that wood mulch is an effective natural and low-cost electron donor to stimulate the complete reductive dechlorination of chlorinated solvents to ethene. Being a side-product of the wood industry, mulch can be used in environmental remediation, an approach which perfectly fits the principles of circular economy and addresses the compelling needs of a sustainable and low environmental impact remediation. The efficacy of mulch was further improved by the co-presence of iron filings, which accelerated the conversion of vinyl chloride into the ethene by increasing the H2 availability rather than by catalyzing the direct abiotic dechlorination of contaminants. Chemical analyses were corroborated by biomolecular assays, which confirmed the stimulatory effect of the selected amendments on the abundance of Dehalococcoides mccartyi and related reductive dehalogenase genes. Overall, this paper further highlights the application potential and environmental sustainability of wood mulch-based amendments as low-cost electron donors for the biological treatment of chlorinated ethenes.

scholarly journals Preparation of Porous Hydroxyapatite Using Cetyl Trimethyl Ammonium Bromide as Surfactant for the Removal of Lead Ions from Aquatic Solutions

Polymers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1617
Author(s):  
Silviu-Adrian Predoi ◽  
Carmen Steluta Ciobanu ◽  
Mikael Motelica-Heino ◽  
Mariana Carmen Chifiriuc ◽  
Monica Luminita Badea ◽  
...  
Keyword(s):  
Cetyl Trimethyl Ammonium Bromide ◽  
Morphological Changes ◽  
Low Cost ◽  
Lead Ions ◽  
Ammonium Bromide ◽  
Porous Hydroxyapatite ◽  
X Ray ◽  
Composition And Structure ◽  
Cetyl Trimethyl Ammonium ◽  
Co Precipitation

In the present study, a new low-cost bioceramic nanocomposite based on porous hydroxyapatite (HAp) and cetyl trimethyl ammonium bromide (CTAB) as surfactant was successfully obtained by a simple chemical co-precipitation. The composition and structure of the HAp-CTAB were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), scanning electron microscope (SEM) equipped with an energy dispersive X-ray (EDX) spectrometer, and N2 adsorption/desorption analysis. The capacity of HAp-CTAB nanocomposites to remove the lead ions from aqueous solutions was studied by adsorption batch experiments and proved by Langmuir and Freundlich models. The Pb2+ removal efficiency of HAp-CTAB biocomposite was also confirmed by non-destructive ultrasound studies. The cytotoxicity assays showed that the HAp-CTAB nanocomposites did not induce any significant morphological changes of HeLa cells after 24 h of incubation or other toxic effects. Taken together, our results suggests that the obtained porous HAp-CTAB powder could be used for the decontamination of water polluted with heavy metals, such as Pb2+.

scholarly journals Low-temperature combustion of methane over graphene templated Co3O4 defective-nanoplates

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dian Gong ◽  
Gaofeng Zeng
Keyword(s):  
Low Temperature ◽  
Transition Metal Oxides ◽  
Active Oxygen Species ◽  
Low Cost ◽  
Thermal Reduction ◽  
Low Temperature Combustion ◽  
Solid Catalysts ◽  
Intermittent Feeding ◽  
Co Precipitation ◽  
Catalytic Combustion Of Methane

AbstractTransition metal oxides are the potential catalysts to replace noble-metal based catalyst for the catalytic combustion of methane due to the tolerable reactivity and low cost. However, these catalysts are challenged by the low temperature reactivity. Herein, the surface defective Co3O4 nanoplates are realized through a facile co-precipitation and thermal reduction method with the association of GO. The resultant catalysts (CoGO50) demonstrate a superior low-temperature reactivity for the methane oxidation to CO2 and H2O in comparison with the common Co3O4 catalyst. The reliable stability of CoGO50 catalyst was proved by 80 h testing with intermittent feeding of water vapor. The experimental analysis demonstrates that the presence of a small amount of GO significantly affects the catalysts in surface valence state, active oxygen species and surface oxygen vacancies through reacting with the cobalt oxide as a reductant. Moreover, GO plays as 2D confine template to form smaller and thinner nanoplates. This work provides a facile method to control the surface properties of catalyst not only for Co3O4 based catalysts but also for wider solid catalysts.

Printing ultrathin graphene oxide nanofiltration membranes for water purification

2017 ◽  
Vol 5 (39) ◽  
pp. 20860-20866 ◽  
Author(s):  
Mahdi Fathizadeh ◽  
Huynh Ngoc Tien ◽  
Konstantin Khivantsev ◽  
Jung-Tsai Chen ◽  
Miao Yu
Keyword(s):  
Graphene Oxide ◽  
Water Purification ◽  
Inkjet Printing ◽  
Low Cost ◽  
Nanofiltration Membranes ◽  
Highly Effective ◽  
First Time ◽  
Polymeric Supports ◽  
Effective Water

We demonstrated for the first time that inkjet printing can be a low-cost, easy, fast, and scalable method for depositing ultrathin (7.5–60 nm) uniform graphene oxide (GO) nanofiltration membranes on polymeric supports for highly effective water purification.

scholarly journals Povidone-Iodine Attenuates Viral Replication in Ocular Cells: Implications for Ocular Transmission of RNA Viruses

Biomolecules ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 753
Author(s):  
Sneha Singh ◽  
Onkar B. Sawant ◽  
Shahzad I. Mian ◽  
Ashok Kumar
Keyword(s):  
Epithelial Cells ◽  
Viral Replication ◽  
Povidone Iodine ◽  
Rna Viruses ◽  
Retinal Pigment ◽  
Retinal Pigment Epithelial Cells ◽  
Host Cells ◽  
Eye Banking ◽  
Antiviral Effects ◽  
Infected Cells

Several RNA viruses, including SARS-CoV-2, can infect or use the eye as an entry portal to cause ocular or systemic diseases. Povidone-Iodine (PVP-I) is routinely used during ocular surgeries and eye banking as a cost-effective disinfectant due to its broad-spectrum antimicrobial activity, including against viruses. However, whether PVP-I can exert antiviral activities in virus-infected cells remains elusive. In this study, using Zika (ZIKV) and Chikungunya (CHIKV) virus infection of human corneal and retinal pigment epithelial cells, we report antiviral mechanisms of PVP-I. Our data showed that PVP-I, even at the lowest concentration (0.01%), drastically reduced viral replication in corneal and retinal cells without causing cellular toxicity. Antiviral effects of PVP-I against ZIKV and CHIKV were mediated by direct viral inactivation, thus attenuating the ability of the virus to infect host cells. Moreover, one-minute PVP-I exposure of infected ocular cells drastically reduced viral replication and the production of infectious progeny virions. Furthermore, viral-induced (CHIKV) expression of inflammatory genes (TNF-α, IL-6, IL-8, and IL1β) were markedly reduced in PVP-I treated corneal epithelial cells. Together, our results demonstrate potent antiviral effects of PVP-I against ZIKV and CHIKV infection of ocular cells. Thus, a low dose of PVP-I can be used during tissue harvesting for corneal transplants to prevent potential transmission of RNA viruses via infected cells.

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