scholarly journals ASSESSMENT OF SOCIAL AND ECONOMIC DAMAGE ASSOCIATED WITH MORTALITY FROM RESPIRATORY CANCER IN THE TOMSK REGION (2005–2016)

2021 ◽  
Vol 20 (4) ◽  
pp. 21-29
Author(s):  
L. D. Zhuikova ◽  
E. L. Choynzonov ◽  
O. A. Ananina ◽  
A. S. Zhuikova ◽  
T. V. Polychuk

Introduction. A significant component in the system analysis of anti-cancer activities is the assessment of the impact of mortality on life expectancy, which indicates the social and economic situation in the region.Material and methods. The economic damage caused by laryngeal and lung cancer mortality in the Tomsk region for the period 2005–2016 was analyzed using the database of the regional cancer registry and local agency of federal state statistics service of the tomsk region.Results. The loss of the male working population ranged from 106.0 (2012–2013) to 161.5 (2008–2009) person/years of lifetime from larynx cancer and from 1058.5 (2013–2014) to 1576.3 (2006–2007) person/years of lifetime from lung cancer. The female working population lost up to 34.0 (2013–2014) person/years of lifetime due to mortality from larynx cancer and from 1445.3 (2005–2006) to 2553.9 (2015–2016) person/years of lifetime from lung cancer. The average number of undelivered years in working age due to the premature death of one man averaged 6.1 ± 2.0 years from larynx cancer and 11.1 ± 1.3 from lung cancer, one woman averaged 4.6 ± 0.9 years from larynx cancer and 6.2 ± 0.3 years from lung cancer. Economic losses associated with mortality from cancer of the respiratory system amounted to 2.251.97 million rubles: 202.07 million rubles from laryngeal cancer and 2.049.90 million rubles from lung cancer.Conclusion. The quantitative analysis of social and economic losses associated with mortality from cancer of the respiratory system enables the regional health authorities to develop and implement anti-cancer interventions to maximize the use of funds for the prevention, treatment and rehabilitation of cancer patients.

2020 ◽  
Vol 1 (11) ◽  
pp. 133-140
Author(s):  
E. V. DMITRIEVA ◽  

The article considers topical issues of economic support for the development of the regional security system of the population against various risks. The dependence of the impact of the scale of crisis situations on economic activities in the constituent entities of the Russian Federation, which become a serious barrier to the sustainable development of the regions of the country, was investigated. The increasing importance of risks of economic losses from accidents and disasters at potentially dangerous facilities as a result of the complex influence of natural, manmade and fire factors has been established. An analysis was carried out and proposals were developed to implement the key tasks of the state in the field of ensuring the protection of the population and territories of the country from disasters in order to ensure the stability of the economy. The organizational structure, division of tasks and functions between officials, crisis management structures and responding units were analyzed, taking into account the reduction in current financial costs. On the basis of a study of the peculiarities of the regions of the country, recommendations were formed to fulfill the necessary tasks by the anti-crisis management bodies in the field of reducing economic damage on the basis of preventing crisis situations and ensuring fire safety. It is proposed to organize the practical application of a complex automated security system based on modern developments with the application of improving the qualities and efficiency of anti-crisis management processes in order to increase economic efficiency. Initial data were formed to reduce potential threats of a natural, man-made, fire and other nature in the regions using financial and economic mechanisms. It is proposed to implement a set of priority measures to further improve and increase the potential of economic support for the anti-crisis management system. The materials of the article can be used in planning the main directions of the development of the regional population security system and the implementation of socio-economic development programs.


2020 ◽  
Vol 17 (6) ◽  
pp. 92-101
Author(s):  
I. V. Alibekova ◽  
E. V. Kulakova ◽  
T. T. Kaverzneva ◽  
T. A. Shendakova

Construction is one of the most dangerous industries, which is in fourth place in terms of industrial injuries. Various harmful industrial factors of the industry cause both occupational diseases and diseases with temporary disability. In this regard, economic losses are — lost profit, payment of sick leave, medical care, rehabilitation measures, as well as loss of efficiency, calculated in millions of person-days per year. Thus, due to the impact of a set of unfavorable factors on workers, on the one hand, there is a decrease in working capacity, a shortening of the terms of full-fledged labor activity, an increase in occupational diseases and injuries, on the other hand, significant economic damage to both the individual organization and the industry as a whole. The specifics of construction activity is that working conditions are usually constantly changing, so the data of a special assessment of working conditions, which is carried out every five years, lose their reliability. It is proposed to conduct continuous monitoring of working conditions at each workplace in order to identify and rank production factors that have the most adverse impact on the health of the employee and further develop appropriate measures to normalize working conditions.


2019 ◽  
Vol 21 (2) ◽  
pp. 6-9 ◽  
Author(s):  
Evgeny L Choynzonov ◽  
Lilia D Zhuikova ◽  
Olga A Ananina ◽  
Irina N Odintsova ◽  
Lidia V Pikalova

Aim. To study the incidence and mortality of lung cancer (LC) in the Tomsk region and to assess the economic damage. Materials and methods. The population-based cancer registry data collected at Tomsk Regional Cancer Center and the Federal State Statistics for 2007-2017 were used. The extensive, intensive and standardized variables were analyzed. Results. LC was the 4-th most common cancer, comprising 10.4% (10.1% in the RF) of all cancer cases in the Tomsk region in 2017. It ranked as the first most prevalent cancer for men (17.0%) and the 6-th for women (4.7%). The LC incidence rate decreased by 19.6%, reaching 29.5±1.3 per 100 000 (р=0.0149). It decreased in men (р=0.0006) but was stable in women. In 2017, the lifetime risk of cancer was higher in the Tomsk region than that in the RF, being 7.3% for men and 1.5% for women. LC was the most common cause of mortality from cancer for both sexes (18.9%), being the most common in men (28.1%) and the 4-th most common in women (8.0%). The mortality rate was higher in men than in women (55.6 versus 6.0; р=0.0012). In 2016, the total loss of the life potential in men amounted to 8.4 thousand, for women - 2.5 thousand man-years. Economic damage in the form of conditionally non-produced national income was growing and in 2016 amounted to 263.7 million rubles. Conclusion. Epidemiological analysis of LC in the Tomsk region indicates the relevance of improving the anticancer struggle with the development and implementation of ideas aimed at increasing the cancer literacy of the population and the alertness of primary care physicians, the formation and monitoring of risk groups, the timely routing of patients with suspected cancer.


2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e18075-e18075 ◽  
Author(s):  
Richard John Cassidy ◽  
Xinyan Zhang ◽  
Pretesh R Patel ◽  
Joseph W Shelton ◽  
Sibo Tian ◽  
...  

e18075 Background: Octogenarians and nonagenarians with stage III lung cancer are underrepresented in randomized trials that established the standard of care therapy of concurrent chemoradiation (CRT). The purpose of this study was to investigate factors predictive of and the impact on overall survival (OS) following CRT among patients ≥80 years old with stage III non-small cell lung cancer (NSCLC) in the National Cancer Data Base (NCDB). Methods: In the NCDB, patients ≥80 years old from 2004 to 2013 with stage III NSCLC were queried. Logistic regression, Kaplan-Meier method, and Cox-proportional hazard regression analyses were performed as well as propensity-score matched (PSM) analysis to reduce treatment selection bias. Results: A total of 12,641 stage III NSCLC patients ≥80 years old were identified with complete treatment and OS records; 7,921 (62.7%) received no treatment, 1,153 received definitive radiation alone (9.1%), and 3,567 (28.2%) received CRT. On multivariable analysis (MVA), black race, female gender, advancing age, residence in a lower-educated county, adenocarcinoma histology, and patients with stage IIIB tumors were associated with receiving no anti-cancer therapy while treatment at an academic facility and lower comorbidity status were associated with receiving anti-cancer treatment (all p < 0.05). On MVA, male gender, advancing age, non-adenocarcinoma histology, higher tumor grade, larger tumors, advancing T and N stage, stage IIIB tumors (vs. IIIA), delayed start to CRT, and not receiving CRT were associated with worse OS (all p < 0.05). OS rates at 1 and 5 years was 53.7% and 10.1% respectively for patients receiving CRT compared to 16.4% and 3.3% respectively for all other therapies (p < 0.01). PSM analysis confirmed that not receiving CRT was associated with worse OS (HR = 1.23, 95% CI 1.11-1.34; p < 0.01). Conclusions: A significant portion of patients ≥80 years old with stage III NSCLC do not receive treatment. Black race, female gender, advancing age, and residence in a lower-educated county were associated with not receiving therapy. In this NCDB series, OS is higher in patients ≥80 years old receiving CRT, even when adjusting for patient- and tumor-related factors.


2018 ◽  
Vol 17 (3) ◽  
pp. 5-10
Author(s):  
E. L. Choynzonov ◽  
L. D. Zhuikova ◽  
I. N. Odintsova

A retrospective epidemiological analysis of the mortality from respiratory system cancer among the population of the Tomsk region for a ten-year period was carried out using data drawn from  the official population and mortality statistics of the Tomsk region.  Cancer has the second leading cause of death behind cardiovascular disease. Respiratory system cancer is the 3-rd most  common cause of cancer-related death after cancers of the digestive system and genital organs. The standardized mortality  rate for respiratory system cancer among the rural population is significantly higher than that in the urban population (p<0.05). Over the study  period, the respiratory system mortality rate decreased for males  (р=0.0000) and remained relatively constant for females. The  lifetime risk of dying from respiratory system cancer in 2016 in the  Tomsk region was higher than the national average. For men, it was  the highest among the main localizations. Compared to 2007, the  mortality rate decreased, as the risk of lung cancer death in men  decreased. The lifetime risk of dying from respiratory system cancer  was higher in the rural population than in the urban population. The indicator of «severity» of the disease indicates an unfavorable  situation in terms of quality and completeness of statistical recording of patients and early diagnosis of respiratory cancer, especially in  urban areas of the Tomsk region. In order to ensure timely and  adequate routing of patients with suspected malignant neoplasm and  timely diagnosis, the continued implementation of the Population-based Cancer Registry with coverage of all administrative territories and areas is of great importance.


2021 ◽  
Vol 845 (1) ◽  
pp. 012145
Author(s):  
A A Dubovitski ◽  
M E Konovalova ◽  
T D Strelnikova ◽  
N V Pilipchuk ◽  
I N Shvetsova

Abstract Understanding the possible climate risks and potential economic losses of agribusiness in different regions is becoming a determining factor in the strategic planning of agricultural activities in the context of global warming. The purpose of this work was to assess the climate risks for agriculture in Russia. The study was conducted using techniques and tools of multivariate correlation analysis. The authors investigated the influence of deviations of the average monthly amounts of temperatures and precipitation from the average long-term values on the deviation of grain yields, using a set of data for 17 regions of the Central Federal district of Russia for the period of 2000-2019. The results showed that a smooth change in the parameters of heat and precipitation does not significantly affect the yield of grain crops. At the same time, increasing annual temperature variability and precipitation significantly reduce yields. An increase in the frequency of extreme events causes a growth in the probability of environmental and economic damage and the magnitude of climate risks. The maximum level of climate risk requires an appropriate adjustment of the agribusiness development strategy and the creation of an institution in society of fair compensation for damage caused by global warming factors.


2016 ◽  
Vol 1 (13) ◽  
pp. 162-168
Author(s):  
Pippa Hales ◽  
Corinne Mossey-Gaston

Lung cancer is one of the most commonly diagnosed cancers across Northern America and Europe. Treatment options offered are dependent on the type of cancer, the location of the tumor, the staging, and the overall health of the person. When surgery for lung cancer is offered, difficulty swallowing is a potential complication that can have several influencing factors. Surgical interaction with the recurrent laryngeal nerve (RLN) can lead to unilateral vocal cord palsy, altering swallow function and safety. Understanding whether the RLN has been preserved, damaged, or sacrificed is integral to understanding the effect on the swallow and the subsequent treatment options available. There is also the risk of post-surgical reduction of physiological reserve, which can reduce the strength and function of the swallow in addition to any surgery specific complications. As lung cancer has a limited prognosis, the clinician must also factor in the palliative phase, as this can further increase the burden of an already compromised swallow. By understanding the surgery and the implications this may have for the swallow, there is the potential to reduce the impact of post-surgical complications and so improve quality of life (QOL) for people with lung cancer.


2018 ◽  
Vol 64 (6) ◽  
pp. 732-738
Author(s):  
Yevgeniy Choynzonov ◽  
Lyubov Pisareva ◽  
Liliya Zhuykova ◽  
Olga Ananina ◽  
Irina Odintsova

Respiratory system cancer (cancer of the nasal cavity, middle ear, paranasal sinuses (C30-31), larynx (C32), trachea, bronchi and lung (C33-34) is one of the most common malignancies in the Tomsk region, comprising 12.9% of all cancer cases. The purpose of the study was to analyze the respiratory system cancer incidence among the population of the Tomsk region. Materials and methods. The study was based on cancer register data collected at the Cancer Research Institute and Tomsk Regional Cancer Center, and covered the period 2005-2016. Results. Respiratory system cancer is the most common cancer in men, comprising 21.7% and the 6-th most common cancer in women, comprising 5.1. The incidence of respiratory system cancer decreased in men and showed an increasing tendency in women. The age-standardized incidence rates in the Tomsk region were expected to be 58.3 per 100,000 males and 12.8 per 100,000 females by 2020. Conclusion. Early detection and prediction of respiratory system cancer should play a vital role in the diagnosis process and also increase the survival rate of patient.


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