scholarly journals Prediabetes: challenges and opportunities

2021 ◽  
pp. 220-227
Author(s):  
T. B. Morgunova ◽  
I. V. Glinkina ◽  
V. V. Fadeev
Keyword(s):  
Diabetes Mellitus ◽  
Carbohydrate Metabolism ◽  
Lifestyle Modification ◽  
Risk Group ◽  
Lifestyle Changes ◽  
Moderate Intensity ◽  
Number Of Patients ◽  
Antihyperglycemic Therapy ◽  
The World ◽  
Patients With Diabetes

In the world, the number of patients with carbohydrate metabolism disorders is steadily growing. Over the past 10 years, the number of patients with diabetes mellitus in the world has more than doubled. Moreover, there is not only an increase in the number of patients with diabetes mellitus, predominantly type 2 diabetes, but also with prediabetes. The term «prediabetes» means impaired glucose tolerance and impaired fasting glycemia. To date, it is obvious that the development of prediabetes lead not only to the higher risk of diabetes mellitus in the future, but also of cardiovascular diseases. Factors that increase the risk of cardiovascular events in patients with prediabetes includeare the following: insulin resistance, accompanied by arterial hypertension and dyslipidemia, and postprandial hyperglycemia. Therefore, it is very important to timely identify patients from the risk group, diagnose and treat carbohydrate metabolism disorders already at the stage of prediabetes. Also it is very important to identify the patients from the risk group, diagnose and treat carbohydrate metabolism disorders at the stage of prediabetes. Treatment of patients with prediabetes implies, first of all, lifestyle modification (moderate hypocaloric nutrition with predominant restriction of fats and simple carbohydrates and regular physical activity of moderate intensity) in order to reduce weight. If lifestyle changes are ineffective, drug therapy may be prescribed. The article discusses the studies conducted to assess the effectiveness of lifestyle modification, as well as various options for antihyperglycemic therapy (metformin, glucagon-like peptide receptor agonists, alpha-glucosidase inhibitors, orlistat) for the treatment of patients with prediabetes. It also provides data on long-term follow-up of patients with prediabetes who received different treatment options. 

SWEETWISE: developing a multi-professional approach to diabetes mellitus

2015 ◽  
Vol 17 (02) ◽  
pp. 107-113
Author(s):  
Amrit Takhar ◽  
Jenny Herbert ◽  
Rosemary Plum ◽  
Mukesh Lad ◽  
Deborah Manger ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Lifestyle Modification ◽  
Continuing Professional Development ◽  
Health Checks ◽  
Professional Network ◽  
Number Of Patients ◽  
Patients With Diabetes ◽  
Patient Advice ◽  
Audit Project ◽  
Improve Health

The formation of a local joint professional network (LJPN) in Northamptonshire has led to a joint Continuing professional development initiative and an audit project to determine the take up of annual health checks by patients with diabetes mellitus with dentists, optometrists, pharmacists as well as the usual check with the General Medical Practice team. The findings showed that a significant number of patients (29–50%) do not access available dental, optometry and pharmacy advice. Better collaboration between the professions has the potential to improve health outcomes in diabetes mellitus and other areas where lifestyle modification reduces adverse health risks. A patient advice card (SWEETWISE) was developed by the group and could be used to help educate patients and health professionals.

scholarly journals PROTEOLYTIC SYSTEM CONDITION AS IN THE CASE OF NEUTROPHIL ELASTASE IN PATIENTS WITH TROPHIC ULCERS ON THE BACKGROUND OF DIABETES MELLITUS

2020 ◽  
Vol 8 (4) ◽  
pp. 346-350
Author(s):  
A.S. Nikolaienko
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
International Diabetes Federation ◽  
Poor Quality ◽  
Proteolytic System ◽  
Financial Costs ◽  
Number Of Patients ◽  
The World ◽  
Patients With Diabetes

According to the WHO and the International Diabetes Federation (IDF), the number of patients with diabetes in the world reached 463 million people in 2019. A typical manifestation of complications of diabetes mellitus is the development of trophic ulcers of the lower extremities, which leads to poor quality of life, disability, and high financial costs for treatment.

scholarly journals Diabetes mellitus and COVID-19. How are they connected? Current strategy of fight

2020 ◽  
Vol 26 (3) ◽  
pp. 304-311
Author(s):  
A. Yu. Babenko ◽  
M. Yu. Laevskaya
Keyword(s):  
Diabetes Mellitus ◽  
Pancreatic Beta Cells ◽  
Mutual Influence ◽  
The Other ◽  
Direct Damage ◽  
Antihyperglycemic Therapy ◽  
The World ◽  
Patients With Diabetes ◽  
Coronavirus Infection ◽  
Successful Prevention

Infectious epidemic of COVID-19 caused by the new coronavirus is characterized by severe course in patients with diabetes mellitus, which presents another noninfectious pandemic accelerating for last decades. Today, according to the International Diabetic Federation data, there are 463 million patients with diabetes mellitus in the world. The burden of the COVID-19 epidemic is largely explained by a frequent combination of these two pathologies. From the previous flu epidemics and already available data of the current epidemic, diabetes mellitus and obesity are considered to be the predictors of more severe course of COVID-19 and mortality. On the other hand, SARS-CoV-2 can aggravate diabetes mellitus, via direct damage of pancreatic beta cells and the liver injury, resulting in higher insulin resistance. We discuss the mechanisms underlying the relation between coronavirus infection and diabetes mellitus and consequences of their mutual influence. Also the article reviews potential strategies of personalized therapy in COVID-19. Timely control and maintenance of individualized target glycemic level is the cornerstone of successful prevention of COVID-19 complications. Disease severity defines strategy of treatment and the choice of antihyperglycemic therapy.

scholarly journals Analisis faktor yang berhubungan dengan kemampuan pasien diabetes mellitus dalam melakukan deteksi episode hipoglikemia

2020 ◽  
Vol 14 (1) ◽  
pp. 8-16
Author(s):  
Eka Yudha Chrisanto ◽  
Sapti Ayubbana ◽  
Yola Anjani
Keyword(s):  
Diabetes Mellitus ◽  
Lifestyle Changes ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Patients With Diabetes ◽  
Sample Technique ◽  
Adult Diabetes ◽  
Relationship Of

Detection of hypoglycemia by adult with diabetes mellitus.Background : The increasing prevalence of people with diabetes mellitus occurs every year along with the increasing prosperity of a country, especially in developing countries because the wrong lifestyle changes can cause obesity which is one of the risk factors for diabetes.Purpose: Know factors that are related to Detection of hypoglycemia by adult with diabetes mellitus.Method: This is a descriptive correlational study, a cross sectional research design. The population in this study was the number of patients with diabetes mellitus of 40 respondents. The sample technique used was accidental sampling, research instruments using a questionnaire, with data analysis namely the chi square test.Results: Finding that there was no relationship of age (p-value 0.071) and availability of glucometer with (p-value 0.052), there was a relationship with education (p-value 0.026), duration of suffering of DM (p-value 0.016 ), there is a relationship of gender with (p-value 0.010), there is a relationship of knowledge (p-value 0.008). In detecting episodes of hypoglycemia (p-value 0.052).Conclusion: Several factors in detecting episodes of hypoglycemia in the context of nursing care are closely related such as; education, duration of diabetes, gender, and knowledge.Keywords: Detection; Hypoglycemia; Adult; Diabetes mellitus.Pendahuluan: Hipoglikemia terjadi karena peningkatan insulin dalam darah dan penurunan kadar glukosa. Terapi insulin yang tidak adekuat disebabkan oleh ketidaksempurnaan terapi insulin saat ini, dimana pemberian insulin masih belum sepenuhnya dapat menirukan (mimicking) pola sekresi insulin yang fisiologis. Hipoglikemia diabetik lebih sering terjadi pada pasien diabetes tipe 1, namun dapat juga terjadi pada pasien diabetes tipe 2 yang mendapatkan terapi insulin, dan merupakan faktor penghambat utama dalam penanganan diabetes mellitus.Tujuan: Mengetahui faktor faktor yang berhubungan dengan kemampuan pasien diabetes mellitus dalam melakukan deteksi episode hipoglikemia dalam konteks asuhan keperawatan .Metode: Penelitian dilakukan pada Juli 2019 dengan menggunakan metode Cross Sectional. Melibatkan 40 responden di Poli Penyakit Dalam Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Propinsi Lampung. Pengumpulan data dilakukan dengan cara wawancara langsung menggunakan kuisioner pengetahuan tentang Hipoglikemia untuk menilai tingkat pengetahuan dan kuisioner kemampuan deteksi hipoglikemia untuk menilai kemampuan melakukakn deteksi episode hipoglikemia pada responden.Hasil: Tidak terdapat hubungan usia (p-value 0.071) dan ketersediaan alat glukometer dengan (p-value 0.052), terdapat hubungan pendidikan dengan (p-value 0,026), lama menderita DM dengan (p-value 0,016), jenis kelamin dengan (p-value 0,010), dan pengetahuan (p-value 0,008) dalam melakukan deteksi episode hipoglikemia dalam konteks asuhan keperawatan (p-value 0,052).Simpulan: Beberapa faktor dalam melakukan deteksi episode hipoglikemia dalam konteks asuhan keperawatan sangat erat berhubungan seperti; pendidikan, lama menderita DM, jenis kelamin, dan pengetahuan

scholarly journals FEATURES OF GLYCEMIA INDICES DYNAMICS IN THE COURSE OF SURGICAL TREATMENT OF PATIENTS WITH LOCAL WOUNDS AND DIABETES MELLITUS

2016 ◽  
pp. 53-59
Author(s):  
I. A. Slavnikov ◽  
Z. A. Dundarov
Keyword(s):  
Diabetes Mellitus ◽  
Surgical Treatment ◽  
Carbohydrate Metabolism ◽  
Conservative Therapy ◽  
Impaired Glucose Metabolism ◽  
Antihyperglycemic Therapy ◽  
Different Types ◽  
Patients With Diabetes ◽  
Long Acting ◽  
Persistent Hyperglycemia

Objective: to determine regularities of the dynamics of carbohydrate metabolism indices in the application of various techniques of the treatment for local wounds in patients with diabetes mellitus. Material and methods. We studied the glycemia dynamics in 83 patients with different types and duration of diabetes mellitus who had local wounds of various genesis and limitation period. We applied various ways of conservative therapy and surgical treatment of wound defects and also their combinations in the out-patient conditions of hospital. Hypocarbohydrate diet, various schemes of insulin therapy with short and long acting preparations, oral application of antihyperglycemic preparations of biguanide and sulfonylurea groups, and also their combination were applied as antihyperglycemic therapy. Results. Elimination of local wound defects with a small amount of necrotic mass or its absence in patients with different types of diabetes mellitus by means of various conservative techniques and operative treatment leads to the decrease of prandial glucose concentration in capillary blood. Patients with significant volume of wound detritus did not reveal such a relation. Conclusion. Necrotizing tissues in the area of a local wound defect in patients with impaired glucose metabolism are the cause of persistent hyperglycemia in these patients. This is an unfavorable factor for medicinal compensation of carbohydrate metabolism.

scholarly journals DISRUPTION OF CARBOHYDRATE METABOLISM IN PATIENTS WITH SEPSIS

2020 ◽  
pp. 46-50
Author(s):  
S. D. Shapoval ◽  
I. L. Savon ◽  
O. O. Maksimova ◽  
L. A. Vasilevskaja ◽  
M. M. Sofilkanich ◽  
...  
Keyword(s):  
Carbohydrate Metabolism ◽  
Type I ◽  
Case Histories ◽  
Septic Complications ◽  
Number Of Patients ◽  
Starting Point ◽  
The World ◽  
Patients With Diabetes ◽  
Hygienic Measures ◽  
Group 1

Summary. Introduction Every year, 18–20 million cases of sepsis are recorded in the world, 30 % of which result in death. Hopes that with the development of sanitary-hygienic measures the dynamics of sepsis will decrease, turned out to be illusory. The annual increase in the frequency of sepsis is 8.7 %, while it is noted that the number of patients with impaired carbohydrate metabolism increases by 8-27 %. Materials and methods. 5612 case histories of patients with purulent-septic diseases who were treated at the center for the period 2015-2019 were analyzed. Results. It was found that 213 (3.8 %) patients had diabetes mellitus (DM) type I or II (group 1), and the number of patients with complicated diabetic foot syndrome (SDS) was 43.3 % of the total number of patients (2431 patients) — 2 group. The development of sepsis in patients of the 1st group was recorded in 1.4 % of cases (46 patients), while in patients with complicated SDS — in 8.3 % (202 patients). Among the latter, in the overwhelming majority of cases, the starting point in the development of sepsis was “wet” gangrene of the lower extremities. Conclusions. In patients with diabetes, the risk of developing septic complications is significantly higher than in patients without impaired carbohydrate metabolism.

scholarly journals Association between obesity and depression in patients with diabetes mellitus type 2; a study protocol

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 7 ◽  
Author(s):  
Eduardo De la Cruz-Cano ◽  
Carlos Alfonso Tovilla-Zarate ◽  
Emilio Reyes-Ramos ◽  
Thelma Beatriz Gonzalez-Castro ◽  
Isela Juarez-Castro ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Diabetes Mellitus Type 2 ◽  
Cross Sectional Study ◽  
Diabetes Mellitus Type ◽  
Sectional Study ◽  
Cross Sectional ◽  
The World ◽  
Patients With Diabetes

Background: Diabetes mellitus and depression are highly prevalent conditions throughout the world and have significant impact on health outcomes. It has been estimated that diabetes mellitus type 2 affects about 246 million people in the world; nevertheless, incidence varies among countries. There is evidence that depression is associated with a poor metabolic control in patients with type 2 diabetes mellitus that present other health problems (such as hypertension and obesity). The aim of this study protocol is to determine if obesity increases the risk for depression in patient with diabetes type 2.Methods: The analysis will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).The studies suitable for inclusion will be assessed by the Newcastle-Ottawa Scale (NOS) to determine their methodological quality. To identify the studies of interest, we will search on PubMed and EBSCO databases. We will use the following keyword combinations: "Diabetes Mellitus type 2 AND obesity AND depression", "depression AND Diabetes Mellitus type 2", "Diabetes Mellitus type 2 AND body mass index cross sectional study", "depression AND obesity cross-sectional study". Causes for exclusion will be publications that studied patients diagnosed with diabetes mellitus type 1; articles that focused on the treatment and complications of diabetes mellitus type 2; publications that have studied other clinical or psychiatric conditions (for instance, seizure disorder or history of schizophrenia, bipolar disorder, psychotic symptoms or dementia).Conclusion: The results of this study will form the basis for a better understanding of the association between obesity and depression in patients with diabetes mellitus type 2, and will allow development of prediction tools and better interventions. It is evident that several modifiable and non-modifiable risk factors play an important role in the pathogenesis of diabetes among population. Currently, evidence for the deleterious effects of diabetes mellitus type 2 are based on cross-sectional or other observational designs. Therefore, this study will have important implications for future research and public health guidance.

scholarly journals Prevalence of Depression Symptoms in Diabetes Mellitus

2018 ◽  
Vol 6 (2) ◽  
pp. 340-343 ◽  
Author(s):  
Salih Eker
Keyword(s):  
Diabetes Mellitus ◽  
Depressive Disorder ◽  
Depression Symptoms ◽  
Strong Indicator ◽  
Number Of Patients ◽  
High Prevalence ◽  
Prevalence Of Depression ◽  
The World

BACKGROUND: Diabetes mellitus (DM) is one of the most prevalent diseases all over the world. Prevalence of DM in Turkey is 13.7%. Depression is another condition which has a high prevalence. All over the world, an estimated 300 million people of all ages suffer from depression. The relevance between depression and DM is a well - known condition.AIM: We aimed in this study to find out the prevalence of depression symptoms for DM in an attempt to better manage the disease.METHODS: We preferred the Beck Depression Index (BDI) to evaluate the depression symptoms.RESULTS: The number of patients introduced the study were 171 (101 (59.1%) female). As a results of BDI 67 (39.2%) patients evaluated as normal [29 (28.7%) female], 54 (31.6%) had poor symptoms [35 (34.7%) female], 46 (26.9%) had moderate symptoms [34 (33.7%) female] and lastly only 4(2.3%) had strong symptoms 3 (3.0%) female]. So 50 (29.2%) of patients had median plus strong symptoms. There were statistically significant association between HbA1c stages and depression (P = 0.018).CONCLUSION: Being a patient with DM is a strong indicator that the patient may have a depressive disorder. So the physician who takes care patients with DM should be alert about depression, and the simplest way to accomplish is BDI.

scholarly journals VITAMINS. PREVENTION AND TREATMENT OF COMPLICATIONS IN PATIENTS WITH DIABETES MELLITUS

2017 ◽  
pp. 95-98
Author(s):  
S. V. Podachina
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Optimal Level ◽  
Number Of Patients ◽  
Prevention And Treatment ◽  
Patients With Diabetes

Hyperglycemia is a major cause of complications in patients with diabetes mellitus (DM). Since the optimal level of glycemic control is achieved only in a small number of patients with diabetes mellitus, additional methods of prevention and treatment of complications are strongly recommended. The focus of healthcare specialists is increasing on substances that can affect intracellular pathological processes associated with hyperglycemia. Such drugs or agents include certain vitamins and minerals.

scholarly journals PERBANDINGAN MOTIVASI PENGGUNAAN MODERN DRESSING PADA PENDERITA ULKUS DIABEKTIKUM DI KELURAHAN KALIJIRAK DAN KELURAHAN WONOLOP O KECAMATAN TASIKMADU KARANGANYAR

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Budi Kristanto ◽  
Nur Cahyo Saputro ◽  
Elga Firdian Candra
Keyword(s):  
Diabetes Mellitus ◽  
Study Design ◽  
Analytical Study ◽  
Diabetes Complications ◽  
Wound Care ◽  
Epidemiological Studies ◽  
Diabetic Ulcers ◽  
The World ◽  
Patients With Diabetes ◽  
The Village

ABSTRACTIntroduction: The increasing prevalence of diabetes in the world led to an increase in cases of amputation due to diabetes complications. Epidemiological studies reported more than one million amputations are performed on people with diabetes each year. Therefore, prevention and appropriate management of lesions of the foot is the most important thing. The development of wound care is growing very rapidly in the world of health.Objective: This study aimed to compare the motivation of the use of modern dressings in patients with diabetic ulcers in the Wonolopo and Kalijirak villagedistrict of Karanganyar.Methods: This study is a comparative analytical study design to compare the motivation of the use of modern dressings in patients with diabetic ulcers in the Wonolopo and Kalijirak village district of Karanganyar.Respondents: The study sample was taken from the population of people who have diabetic ulcers in the Village Kalijirak as much as 20 and as many as 20 Wonolopo village.Results: Based on the results of independent sample t test with SPSS for Windows series 18 with α = 5% (0.05), obtained p equal to 0825 which means p> 0.05 it indicates that Ha is not accepted, which means there is no difference in motivation to use modern dressings in patients with diabetes mellitus with diabetic ulcers among respondents in the Village and Village Wonolopo Kalijirak.Keywords: Motivation, Modern dressings, Wound care

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