scholarly journals Analysis of occupational risk factors causing diseases of the circulatory system in medical workers: Literature review

2021 ◽  
pp. 173-180
Author(s):  
L.M. Karamova ◽  
◽  
E.T. Valeeva ◽  
N.V. Vlasova ◽  
R.R. Galimova ◽  
...  

The review focuses on analysis of domestic and foreign literature sources concentrating on influence exerted by occupa-tional factors and factors related to labor process on prevalence of diseases of the circulatory system (CSD) among medical workers. At present, specific features typical for occupational activities performed by medical workers are proven to be among major causes of high CSD prevalence among them. Experts have established most common occupational factors and labor-related factors that are able to induce and stimulate development of cardiovascular pathology. Labor intensity associated with neuro-emotional loads, high responsibility, round-the-clock working regime and night shifts (hazard category 3.2–3.3) is estab-lished to have a leading role among adverse labor-related factors for medical workers. Other significant contributions are made by adverse chemicals and biological agents, noise and ultrasound, laser exposure and ionizing radiation. Some authors showed that CSD prevalence was considerably higher among medical workers than among people employed in other industries. The highest CSD prevalence was detected among medical workers with the most adverse working conditions (hazard category 3.2–3.3). A high degree of occupational conditionality for CSD is typical for surgeons, therapists, and phthisiatricians. Emergency doctors run the highest risk of CSD (RR = 3.1; EF = 67.7 %). Assessment cardiovascular risks according to the SCORE system revealed that approximately 15 % medical workers older than 40 ran moderate cardiovascular risks; medical workers older than 50, high (20.0–22.0 %) or extremely high (10.0–12.5 %) total risks of death due to CSD.

Author(s):  
Kemining W. Yeh ◽  
Richard S. Muller ◽  
Wei-Kuo Wu ◽  
Jack Washburn

Considerable and continuing interest has been shown in the thin film transducer fabrication for surface acoustic waves (SAW) in the past few years. Due to the high degree of miniaturization, compatibility with silicon integrated circuit technology, simplicity and ease of design, this new technology has played an important role in the design of new devices for communications and signal processing. Among the commonly used piezoelectric thin films, ZnO generally yields superior electromechanical properties and is expected to play a leading role in the development of SAW devices.


2021 ◽  
Vol 70 (2) ◽  
pp. 14-22
Author(s):  
Zh. KolumbayevaSh. ◽  

Globalization, informatization, digitalization, led to large-scale changes that have problematized the modern process of upbringing. The modern practice of upbringing in Kazakhstan is aimed at solving the problem of forming an intellectual nation. The key figure in the upbringing process is the teacher. The modernization of public consciousness taking place in Kazakhstan, the renewal of both the content of education and the system of upbringing require understanding not only the content, but also the methodology of the professional training of teachers for the upbringing of children, for the organization of the upbringing system in educational organizations. We believe that the analysis of traditional and clarification of modern methodological foundations of professional training of future teachers of Kazakhstan for upbringing work will give us the opportunity to develop a strategy for training future teachers in the conditions of spiritual renewal of Kazakhstan's society. The article reveals the experience of Abai KazNPU. As a result of the conducted research, we came to the conclusion that the process of training a teacher in Kazakhstan, who has a high degree of ethnic, cultural, and religious diversity, requires strengthening the upbringing and socializing components of the educational process of the university. The strategy of professional training of a modern teacher should be a polyparadigmatic concept with the leading role of ideas of personality-oriented, competence paradigm.


2021 ◽  
pp. 12-17
Author(s):  
A. A. Hotko ◽  
N. S. Rudneva

The article is of an overview nature and contains up-to-date information on comorbid cardiovascular pathology in psoriasis. Various studies have shown that psoriasis is associated with a higher prevalence of CVD risk factors, including hypertension, diabetes mellitus, dyslipidemia, obesity, and metabolic syndrome. The relationship between the severity of psoriasis and the risk of cardiovascular disease, as well as the prognostic risks with mortality rates, are discussed. Proposed common pathogenetic mechanisms include genetic factors, inflammatory pathways, adipokine secretion, insulin resistance, lipoprotein composition and function, angiogenesis, oxidative stress, and hypercoagulability.


Author(s):  
ET Valeeva ◽  
GG Gimranova ◽  
ER Shaikhlislamova

Introduction: In terms of the prevalence and severity of complications, diseases of the circulatory system rank high in the structure of general morbidity among the causes of disability and premature mortality of the working-age population. The main reasons for the increased incidence of cardiovascular diseases are considered to be such behavioral risk factors as smoking, alcohol consumption, poor nutrition, hypertriglyceridemia, overweight, and physical inactivity. By now, contribution of adverse work-related and occupational factors in the development of cardiovascular disorders has been proven as well. Our objective was to study the relationship between work-related and behavioral risk factors and diseases of the circulatory system in oil workers. Methods: We conducted an assessment of working conditions and health status of oil industry workers that included a questionnaire-based survey to identify unmodified and modifiable cardiovascular risk factors, anthropometry, blood pressure measurements, the analysis of lipid metabolism indicators, and examination by a cardiologist. We established that the working conditions of oil production and refinery workers belong to hazard class 3 and may contribute to increased rates of chronic non-communicable diseases including diseases of the circulatory system. The main work-related risk factors for oilmen include vibration, noise, workplace air pollution with saturated hydrocarbons and hydrogen sulfide, as well as the severity of the labor process. Strong interrelationships of the main risk factors were revealed. The proportion of workers with a high risk of developing cardiovascular disorders was about 30 % of the total number of employees. Conclusions: Our findings demonstrate the role of work-related and non-occupational risk factors in the development of diseases of the circulatory system in oil workers and indicate the need to develop appropriate preventive measures.


2016 ◽  
Vol 11 (3) ◽  
pp. 28-37
Author(s):  
Тришина ◽  
Tatyana Trishina ◽  
Павлова ◽  
Olga Pavlova ◽  
Реутов ◽  
...  

The socio-cultural system in the Belgorod region, as follows from the results of sociology research, is characterized by stability and integrity. To a certain extent, it is a result of preserving the significant share of traditionalism in public consciousness. The moral guidelines for most citizens in the region are set by prevailing norms in society, which have a high degree of rejection of various social deviations. Currently, there is a transformation of traditional values and practices in «modern» ones - with the leading role of individualism, escalating consumer demand and gradual refusal from the comprehensive state regulation. However, orientation to the stability, not to the change, is the dominant of mass consciousness.


2012 ◽  
Vol 87 (3) ◽  
pp. 1872-1883 ◽  
Author(s):  
Beth L. Nicholson ◽  
Olga Zaslaver ◽  
Laura K. Mayberry ◽  
Karen S. Browning ◽  
K. Andrew White

ABSTRACTCertain plus-strand RNA plant viruses that are uncapped and nonpolyadenylated rely on RNA elements in their 3′ untranslated region, termed 3′-cap-independent translational enhancers (3′CITEs), for efficient translation of their proteins. Here, we have investigated the properties of the Y-shaped class of 3′CITE present in the tombusvirusCarnation Italian ringspot virus(CIRV). While some types of 3′CITE have been found to function through recruitment of translation initiation factors to the viral genome, notrans-acting translation-related factors have yet been identified for the Y-shaped 3′CITE. Our results indicate that the CIRV 3′CITE complexes with eIF4F and eIFiso4F, with the former mediating translation more efficiently than the latter. In nature, some classes of 3′CITE are present in several different viral genera, suggesting that these elements hold a high degree of modularity. Here, we test this concept by engineering chimeric viruses containing heterologous 3′CITEs and show that the Y-shaped class of 3′CITE in CIRV can be replaced by two alternative types of 3′CITE, i.e., aPanicum mosaic virus-like 3′CITE or an I-shaped 3′CITE, without any major loss inin vitrotranslation or replication efficiency in protoplasts. The heterologous 3′CITEs also mediated whole-plant infections ofNicotiana benthamiana, where distinct symptoms were observed for each of the alternative 3′CITEs and 3′CITE evolution occurred during serial passaging. Our results supply new information on Y-shaped 3′CITE function and provide insights into 3′CITE virus-host compatibilities.


Author(s):  
Ja. G. Samoilova ◽  
I. N. Vorozhtsova ◽  
O. A. Oleynik ◽  
N. M. Diraeva ◽  
N. S. Denisov

The significant spread of obesity among adults and children represents a relevant problem for the modern health care system. Diagnosis and correction of the earliest signs of cardiometabolic disorders in children with obesity are necessary since their monitoring and modification allow to influence the development and prognosis of cardiovascular pathology in the future. This article highlights the current knowledge on the markers of cardiovascular risks such as dyslipidemia, the level of trimethylamine N-oxide, the state of epicardial adipose tissue, and the initial signs of myocardial remodeling.


2013 ◽  
Vol 3 (2) ◽  
pp. 10-15
Author(s):  
Munevera Bećarević ◽  
◽  
Duška Bećirović ◽  
Azijada Beganlić ◽  
Olivera Batić-Mujanović ◽  
...  

Introduction: Factors of cardiovascular risk (CVR) are often grouped in cases with diabetes mellitus (DM) with significant increasment of risk for CV disease . The aim of this research is to determine the frequency of CVR and and total CVR in cases with DM and to investigate connection of CRP of other factors of CVR in total cardiovascular risks. Material and methods: In 92 cases with DM weist values were taken as well as body mass index (BMI), blood pressure, sugar in blood, cholesterol, triglycerides, C reactive protein (CRP) and according to SCORE system the 10 year period of CVR were determined. Results: Out of 92 tested cases with age 55,22± 8,3 years, 63,05% were males and 36,95% were women, 81,5% were with values of sugar in blood >7mmol/l, 44,6% were with values of HbA1C>7% and 63,0% >6,5%. The value of cholesterol were >4,5mmol/l in 87%, triglycerides >1,7mmol/l in 78.3% of tested cases. 81,5% of tested cases were overweight and 49% with larger weight values. Average cardiovascular factor according to SCORE system was 3, 92± 3,7% with significant difference among sexes (M-4,86; W-2,32, p<o,05). According to height value CRP (>3mg/l) 52% of tested cases were with high cardiovascular risk. There is significant positive correlation between CRP and cholesterol level (p<0, 01), triglycerides, blood in sugar, HbA1c and upper values of blood pressure (p<0, 05). Significant correlation between CRP and total cardiovascular risk (p=0, 63) was not evident. Conclusion: Cases with diabetes mellitus have high level of non regulated cardiovascular risk factors. Even though there is significant correlation between CRP and and pressure values, sugar in blood, HbA1c, cholesterol, triglycerides, significant correlation between CRP and total cardiovascular risk in cases with diabetes mellitus is not evident.


2020 ◽  
pp. 096452842092029
Author(s):  
Hyejin Jung ◽  
Sujung Yeo ◽  
Sabina Lim

Objectives The aim of this study was to investigate the effects of acupuncture on major adverse cardiovascular events (MACE), myocardial infarction, stroke and death in hypertensive patients taking anti-hypertensives. Methods Using the Korean National Health Insurance Service—National Sample Cohort (NHIS-NSC) database, this study identified 59,370 patients taking anti-hypertensives who had been diagnosed with hypertension between 2003 and 2006. They were divided into acupuncture and non-acupuncture groups. The follow-up period ended with the diagnosis of myocardial infarction, stroke or death. After propensity score matching (PSM), there were 18,011 patients each in the non-acupuncture and acupuncture groups. We calculated the incidence rate, hazard ratio (HR) and 95% confidence interval (CI) for MACE, myocardial infarction, stroke and death in patients with hypertension using a stratified Cox proportional hazard model. In addition, secondary outcome analyses for stroke and cardiovascular mortality were performed. Results After PSM, the HRs for MACE (0.83, 95% CI 0.80–0.86), all-cause mortality (0.73, 95% CI 0.70–0.76) and myocardial infarction (0.85, 95% CI 0.79–0.92) were significantly lower in the acupuncture group than in the non-acupuncture group. Moreover, the HRs for stroke-related mortality, hemorrhage stroke–related mortality, ischemic stroke–related mortality, ischemic heart disease–related mortality and circulatory system disease–related mortality were significantly lower in the acupuncture group than in the non-acupuncture group. Conclusion This observational study with long-term follow-up extends the evidence base in support of the effectiveness of acupuncture for the management of hypertension and potentially reduce the burden of cardiovascular disease.


1988 ◽  
Vol 4 (2) ◽  
pp. 151-171 ◽  
Author(s):  
Richard W. D'souza ◽  
Harold Boxenbaum

Models are intellectual constructs that pattern selected relationships among the elements of one system to correspond in some way to elements of a second system. In pharmacokinetics, physiological models provide a clearly articulated, rational, explanatory basis for the integration of empirical data; they do this by partitioning the biological system into relevant components (tissues, organs, etc.) and linking them together through the circulatory system. Unlike conventional mammillary compartment models, there is a clear correspondence between model system elements and physiological entities. By virtue of their high degree of physical and biochemical relevance, these models can help provide deep insight into structure, function and mechanism. Pharmacokinetic (and potentially pharmacodynamic) response-time relationships can thus be understood in terms of interconnections and behavior of constituent subsystems. At their worst, these models provide stale or infertile views of reality and thus frustrate and alienate us with the triviality of their insights. At their best, they allow us to understand the accumulation of thought in pharmacokinetics and pharmacodynamics, and help with the integration of data and improvement of experimental design.


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