Pharmacological and Therapeutic Aspects of Plants from the Genus Ferula: A Comprehensive Review

2020 ◽  
Vol 20 (13) ◽  
pp. 1233-1257 ◽  
Author(s):  
Mohammad Sabzehzari ◽  
Mohammad Reza Naghavi ◽  
Motahare Bozari ◽  
Hossein M. Orafai ◽  
Thomas P. Johnston ◽  
...  
Keyword(s):  
Nervous System ◽  
Immune System ◽  
Gastrointestinal Tract ◽  
Medicinal Plants ◽  
Literature Review ◽  
Extensive Literature ◽  
Many Body ◽  
Comprehensive Review ◽  
Food Industries ◽  
Medicinal Properties

Inspired by nature, humankind has been able to attain significant achievements in the drug and food industries. Particularly, medicinal plants are a rich source of medicinal, cosmetic, sanitary, and aromatic substances. Genus Ferula from the Apiaceae family is a plant genus that possesses over 170 species, which have been carefully documented with regard to their medicinal properties. Ferula spp. affects many body organs, and their respective functions, in humans, such as the immune system, gastrointestinal tract, genitourinary, endocrine, respiratory, cardiovascular, nervous system, bone (skeleton), and teeth. In spite of the benefits, ferulosis (Ferula toxicity) is an important aspect of Ferula consumption in humans and animals. Hemorrhagic problems and infertility are important signs of ferulosis. In this review, we have described all of the effects of the active ingredients of Ferula spp. and their mechanisms of actions, when known, based on an extensive literature review. Thus, our review opens a window of the benefits of Ferula as a phyto-pharmaceutical and its therapeutic applications in pharmacy, dentistry, and medicine.

scholarly journals Brushed DC Motor Drives for Industrial and Automobile Applications with Emphasis on Control Techniques: A Comprehensive Review

Electronics ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 887
Author(s):  
Dimitris A. Barkas ◽  
George C. Ioannidis ◽  
Constantinos S. Psomopoulos ◽  
Stavros D. Kaminaris ◽  
Georgios A. Vokas
Keyword(s):  
Literature Review ◽  
Dc Motor ◽  
Motor Drives ◽  
Current Paper ◽  
Extensive Literature ◽  
Comprehensive Review ◽  
Control Techniques ◽  
Basic Operating ◽  
Dc Motor Drives ◽  
And Control

The current paper presents an inclusive survey about the AC to DC and DC to DC converters for brushed DC Motor Drives. An essential number of different AC to DC and DC to DC topologies and control techniques, applied on the brushed DC motor drives are presented. This extensive literature review exposes advantages, disadvantages and limitations besides giving the basic operating principles of various topologies and control techniques.

scholarly journals Can depression be associated with the immune response

2021 ◽  
Author(s):  
Maurício Machado Lenhardt ◽  
Dauana Schwartz ◽  
Bruna K. de F. Silva
Keyword(s):  
Central Nervous System ◽  
Immune Response ◽  
Nervous System ◽  
Depressive Symptoms ◽  
Immune System ◽  
Literature Review ◽  
The Central Nervous System ◽  
Biochemical Components ◽  
Therapeutic Protocols ◽  
Pro Inflammatory Cytokines

Introduction: Depression is a disease of uncertain installation and etiology, the imbalance of neurotransmitters is involved in this process, and stress can be an activator of pro-inflammatory cytokines and trigger depressive symptoms. The organism undergoes modulations due to biochemical changes and these are linked to molecular and biochemical components and by the survival instinct, the human body is stimulated to release substances as a form of protection. The objective of this study is to describe the possible association between a loss of homeostasis of the central nervous system (CNS), changes in the modulation of the immune system, and the development of depressive symptoms. Methods: This is an integrative literature review, available in the virtual health databases: PubMed, MEDLINE, SciELO, and Google Scholar published between the years 2010 to 2020. Results: Studies indicate that cytokines can interfere with the homeostasis of the CNS and that the imbalance of catecholamines and indoleamine is involved in the process of depression. In this sense, studies have focused on neuromodulation by blocking neurotransmitters and neuroreceptors to regulate the immune system. Conclusion: It’s already established that the imbalance in the release and reuptake of neurotransmitters is associated with the onset of the depression, however, current studies show that there may also be an association with the homeostasis of the immune system. Therapeutic protocols aren’t based on the correlation between the immune system and the onset of the disease, so further studies are needed to strengthen this relationship.

scholarly journals Physicochemical and Medicinal Properties of Tualang, Gelam and Kelulut Honeys: A Comprehensive Review

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 197
Author(s):  
Datu Agasi Mohd Kamal ◽  
Siti Fatimah Ibrahim ◽  
Haziq Kamal ◽  
Mohd Izhar Ariff Mohd Kashim ◽  
Mohd Helmy Mokhtar
Keyword(s):  
Wound Healing ◽  
Nervous System ◽  
Physicochemical Properties ◽  
Tropical Rainforest ◽  
Biological Effects ◽  
Physicochemical Characteristics ◽  
High Quality ◽  
Comprehensive Review ◽  
Anti Cancer ◽  
Medicinal Properties

Tualang, Gelam and Kelulut honeys are tropical rainforest honeys reported to have various medicinal properties. Studies related to the medicinal properties and physicochemical characteristics of these honeys are growing extensively and receiving increased attention. This review incorporated and analysed the findings on the biological and physicochemical properties of these honeys. Tualang, Gelam and Kelulut honeys were found to possess a wide variety of biological effects attributed to their physicochemical characteristics. Findings revealed that these honeys have anti-diabetic, anti-obesity, anti-cancer, anti-oxidative, anti-microbial, anti-inflammatory and wound-healing properties and effects on the cardiovascular system, nervous system and reproductive system. The physicochemical properties of these honeys were compared and discussed and results showed that they have high-quality contents and excellent antioxidant sources.

scholarly journals Phytotherapeutic properties of the Caesalpinia genus present in the Caatinga biome

2021 ◽  
Vol 14 (6) ◽  
pp. 31-36
Author(s):  
Kaline Soares Da Silva ◽  
Fernanda Granja da Silva Oliveira ◽  
Paulo Henrique Oliveira De Miranda ◽  
Eduarda Santos de Santana ◽  
Zion Nascimento De Souza ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Literature Review ◽  
Herbal Medicines ◽  
Chemical Study ◽  
Google Scholar ◽  
Easy Access ◽  
Caatinga Biome ◽  
Medicinal Properties ◽  
Anti Inflammatory

The society enjoys a lot of medicinal plants due to their easy access and also due to the effectiveness of their use, currently, the popular use of these plants has been awakening the pharmaco-chemical study of their properties. Brazil with its great biodiversity worldwide, has an endemic biome, the Caatinga has a great diversity of plants with medicinal properties. The present work aimed to unite plants of the Caesalpinia genus with medicinal properties, through a literature review. The research was carried out on the electronic databases Google Scholar, Pubmed and Scielo using the following descriptors: “Plantas Medicinais”, medicinal plants, gênero Caesalpinia, Caesalpinia genus , fitoterápicos, herbal medicines, Caatinga. In total, 142 articles were found, of which 44 were included, with the characteristics of being plants with medicinal properties of the Caesalpinia genus in the Caatinga biome. After surveying the works found, it was possible to identify the following species, Caesalpinia pyramidalis Tul, Caesalpinia Ferrea Mart. Caesalpinia bracteosa Tul, found in the Caatinga biome. Each studied species had particular characteristics, having in common some anti-inflammatory properties, are studied by some researchers and are effective in their popular use.

Gut-Brain-Microbiota Axis and Hypertension: a literature review

2021 ◽  
Vol 27 ◽  
Author(s):  
Young Nam Kwon ◽  
Yong-Jae Kim
Keyword(s):  
Blood Pressure ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Immune System ◽  
Literature Review ◽  
The Novel ◽  
Hypertension Treatment ◽  
Gut Dysbiosis ◽  
Novel Targets ◽  
Regulation Of Blood Pressure

: The gut and brain are linked via various bidirectional pathways, communicate with and affect each other. The interaction be-tween the gut-brain axis and the gut microbiota has attracted much attention in the development of hypertension. In this review, we have discussed the gut-brain-microbiota axis and its association with gut dysbiosis in terms of regulation of blood pressure using the autonomic nervous system, immune system, metabolites, hormones, and neurotransmitters. In addition, the treat-ments using microbiota that have been tried to date are briefly summarized. By understanding the mechanism by which gut-brain-microbiota regulates blood pressure, the novel targets for hypertension treatment or a new therapeutic approach us-ing the gut-brain-microbiota could be investigated.

scholarly journals Herbal medicines in dentistry: history, obtainment methods, and properties of Copaifera multijuga hayne and Baccharis dracunculifolia dc

2016 ◽  
Vol 3 (6) ◽  
pp. 859 ◽  
Author(s):  
Bruna Pinto De los Santos ◽  
Luiz Alberto Kanis ◽  
Jefferson Ricardo Pereira
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Literature Review ◽  
Herbal Medicines ◽  
Hand Search ◽  
Electronic Search ◽  
Improper Use ◽  
Ancient Times ◽  
Medicinal Properties ◽  
Anti Inflammatory

The aim of this study was to do a literature review on herbal medicines used in dentistry. For that purpose, an electronic search of papers in Portuguese, Spanish, and English was performed in the following databases: PubMed, MEDLINE, SciELO, Science Direct, LILACS, and BBO, supplemented by hand search in books, theses, and journals. For the search, the following keywords were used: phytotherapy, Copaifera, and Baccharis dracunculifolia. Medicinal plants have been used since ancient times and some of them such as the Copaifera multijuga Hayne and Baccharis dracunculifolia DC have shown medicinal properties. Different ways to obtain extracts from those plants have been described, as well as their many important properties, such as antimicrobial, anti-inflammatory, and antiseptic effects. However, studies on their medicinal properties are still scarce, which indicates the need for further studies to unravel their effects and possible side effects, as well as implications of improper use of these plants.

Neoplasia in Prosimians: Case Series from a Captive Prosimian Population and Literature Review

2009 ◽  
Vol 46 (4) ◽  
pp. 746-772 ◽  
Author(s):  
A. K. Remick ◽  
A. J. Van Wettere ◽  
C. V. Williams
Keyword(s):  
Literature Review ◽  
Case Series ◽  
Extensive Literature ◽  
Retrospective Evaluation ◽  
Comprehensive Review ◽  
Organ Systems ◽  
Black Lemur ◽  
Otolemur Crassicaudatus ◽  
Gray Mouse Lemur ◽  
Prosimian Species

Neoplastic diseases in prosimians have been sporadically reported in the literature. To provide a comprehensive review of prosimian neoplasia, a retrospective evaluation of neoplasia in a large captive prosimian colony and an extensive literature review were performed. Primates that belong to the Order Primata, Suborder Prosimii with histologic evidence of neoplasia were included. One hundred twenty-three cases of spontaneous neoplasia were identified in 101 prosimians from the Duke Lemur Center, and 124 cases were reported in 116 prosimians in the literature. Overall, this review compiled a total of 247 neoplasms in 217 prosimians. Of the 217 affected animals, 88 of 217 were males (41%), 100 of 217 were females (46%), and sex was not reported in 29 of 217 (13%). Ages ranged from 2 days to 36 years. Prosimian families represented were Lemuridae (80/217 [37%]), Cheirogaleidae (61/217 [28%]), Galagidae (44/217 [20%]), Lorisidae (28/217 [13%]), and Indriidae (4/217 [2%]). The most commonly affected species were the gray mouse lemur (Microcebus murinus) (28/217 [13%]), thick-tailed greater bush baby (Otolemur crassicaudatus) (23/217 [11%]), and black lemur (Eulemur macaco) (19/217 [9%]). Organ systems affected, in order of descending occurrence, were digestive (75/247 [30%]), reproductive (40/247 [16%]), hematopoietic (34/247 [14%]), integumentary (28/247 [11%]), endocrine (26/247 [11%]), and urinary (17/247 [7%]). The respiratory, nervous, musculoskeletal, and cardiovascular systems were infrequently affected. The most common neoplasms were hepatocellular (32/247 [13%]), lymphoma and/or leukemia (29/247 [12%]), biliary (15/247 [6%]), and mammary neoplasms (12/247 [5%]). This article should serve as a valuable reference for the types and relative frequencies of neoplasms that occur in prosimian species.

scholarly journals Functional circuits and signal processing in the enteric nervous system

2020 ◽  
Vol 77 (22) ◽  
pp. 4505-4522 ◽  
Author(s):  
Candice Fung ◽  
Pieter Vanden Berghe
Keyword(s):  
Blood Flow ◽  
Nervous System ◽  
Immune System ◽  
Gastrointestinal Tract ◽  
Enteric Nervous System ◽  
Neurodegenerative Disorders ◽  
Current Knowledge ◽  
External Information ◽  
Cellular Composition ◽  
Gut Function

Abstract The enteric nervous system (ENS) is an extensive network comprising millions of neurons and glial cells contained within the wall of the gastrointestinal tract. The major functions of the ENS that have been most studied include the regulation of local gut motility, secretion, and blood flow. Other areas that have been gaining increased attention include its interaction with the immune system, with the gut microbiota and its involvement in the gut–brain axis, and neuro-epithelial interactions. Thus, the enteric circuitry plays a central role in intestinal homeostasis, and this becomes particularly evident when there are faults in its wiring such as in neurodevelopmental or neurodegenerative disorders. In this review, we first focus on the current knowledge on the cellular composition of enteric circuits. We then further discuss how enteric circuits detect and process external information, how these signals may be modulated by physiological and pathophysiological factors, and finally, how outputs are generated for integrated gut function.

5-HT3A serotonin receptor in the gastrointestinal tract: the link between immune system and enteric nervous system in the digestive form of Chagas disease

2019 ◽  
Vol 118 (4) ◽  
pp. 1325-1329 ◽  
Author(s):  
Jefferson Alvim de Oliveira ◽  
Michelle A. R. Freitas ◽  
Enio Chaves de Oliveira ◽  
Samir Jabari ◽  
Axel Brehmer ◽  
...  
Keyword(s):  
Nervous System ◽  
Immune System ◽  
Gastrointestinal Tract ◽  
Enteric Nervous System ◽  
Chagas Disease ◽  
Serotonin Receptor

High Definition Map for Automated Driving: Overview and Analysis

2019 ◽  
Vol 73 (2) ◽  
pp. 324-341 ◽  
Author(s):  
Rong Liu ◽  
Jinling Wang ◽  
Bingqi Zhang
Keyword(s):  
Literature Review ◽  
Research Effort ◽  
Extensive Literature ◽  
Major Research ◽  
Automated Driving ◽  
High Definition ◽  
Research Focus ◽  
Comprehensive Review ◽  
Development Status ◽  
Key Enabling Technologies

As one of the key enabling technologies for automated driving, High Definition (HD) Maps have become a major research focus in recent years. While increasing research effort has been directed toward HD Map development, a comprehensive review of the overall conceptual framework and development status is still lacking. In this study, we start with a brief review of the highlights of navigation map history, and then present an extensive literature review of HD Map development for automated driving, focusing on HD Map structure, functionalities, and accuracy requirements as well as standardisation aspects. In addition, this study conducts an analysis of HD Map-based vehicle localisation. The numerical results demonstrate the potential capabilities of HD Maps. Some recommendations for further investigation are made.

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