Pharmacutico Analytical Study of Mukta Shukti Bhasma

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Biradar M. H. ◽  
Shankar Gowda ◽  
Madhav Diggavi
Keyword(s):  
General Practice ◽  
Calcium Oxide ◽  
Analytical Study ◽  
Systematic Observation ◽  
Hydrate Form ◽  
Oxide Hydrate ◽  
Study Materials ◽  
Three Samples ◽  
Pharmaceutical Processing ◽  
Pharmaceutical Processes

Background: Mukta Shukti is an aquamarine calcium carbonate compound. Mukta Shukti Bhasma is a classical ethical economical medicament, effective in general practice, pharmaceutical processing as per texts with systematic observation and technological updating is carried out in the present work. Objectives: To prepare Mukta Shukti Bhasma by different Pharmaceutical processes and carry out the analytical study. Materials and Methods: Grahya Ashodhita Mukta Shukti was subjected to Shodhana by Kanji Swedana for 3 hours and then divided into two parts. The first part of Shodhita Mukata Shukti was incinerated totally and after 1st Puta it was divided into two portions, first portion was subjected to Jala Bhavana and incinerated. The second portion was subjected to Kumari Swarasa Bhavana and incinerated. The second part of Shodhita Mukata Shukti was incinerated in Kumari Samputa and subjected to Kumari Swarasa Bhavana and incinerated until they attain Bhasma Siddhi Lakshanas and later all the three samples were subjected to analytical studies. Results: Mukta Shukti Bhasma by Jala Bhavana method, Kumari Bhavana method, and Kumari Samputa method requires 7, 6 and 3 Gajaputas respectively with an average of 324 cow dungs in each and at 793°C temperature. Conclusion: Kumari Bhavita Marana to Mukta Shukti leads to calcite form and Jala Bhavita Marana leads to calcium oxide hydrate form. Chemically Mukta Shukti Bhasma may be in both calcite and calcium oxide hydrate form, and XRD is a method in Standardization of Mukta Shukti Bhasma.

scholarly journals THE MECHANISM OF THE HYDRATION OF CALCIUM OXIDE

1955 ◽  
Vol 33 (5) ◽  
pp. 881-886 ◽  
Author(s):  
Fraser W. Birss ◽  
T. Thorvaldson
Keyword(s):  
Calcium Carbonate ◽  
Calcium Oxide ◽  
Vapor Phase ◽  
Calcium Ions ◽  
Constant Weight ◽  
Burnt Lime ◽  
Three Samples ◽  
Lime Solution ◽  
Solution Mechanism ◽  
Phase Process

Three samples of calcium oxide, designated as A, B, and C, were prepared from calcium carbonate labelled with calcium-45. A was heated to constant weight at 700 °C.; B was heated an additional three hours at 1400 to 1550 °C.; and C was heated six hours at the same temperature. The samples were hydrated in a supersaturated lime solution at 21 °C., the development of activity and the changes in concentration of the solution being determined. The activity entering the solution accounted, according to theory, for the following percentages of the samples passing through the solution during the hydration: A, 27%; B, 57%; C, 94%. These results indicate that sample C ("dead-burnt" lime) hydrated by a "through-solution" mechanism, but that A and B either hydrated partly according to some other mechanism, such as a vapor phase process in the pores of the particles of lime, or the calcium ions failed to reach the bulk of the hydrating liquid before precipitation as calcium hydroxide.

scholarly journals HUBUNGAN ANTARA BERATNYA MANIFESTASI DERMATITIS ATOPIK DENGAN TINGGINYA SKALA KEPRIBAD IAN CEMAS PADA TES MMPI PADA PENDERITA DERMATITIS ATOPIK WANITA DI RSUD DR. SOETOMO

2012 ◽  
Vol 6 (1) ◽  
Author(s):  
Iwan Sis Indrawanto
Keyword(s):  
Skin Disease ◽  
Public Hospital ◽  
Analytical Study ◽  
Emotional Factor ◽  
Three Samples ◽  
The World ◽  
Chronic Skin ◽  
Chronic Skin Disease

Dermatitis Atopic, a kind of chronic skin disease that happens a lot in the world, tend to be increased in number and relatively difficult to treat. Most of them appear along with another atop ic condition such as Hay and asthma. The cause is not clearly un derstood yet. It’s thought to be the combination of genetics and environment. Many says that ther e’s emotional factor involved. It’s not the cause of the disease but it worsen or triggers the relaps. People of Dermatitis  Atopic with anxious kind of  personality have prone to relaps e easier than those who are not. This study figured out whether the degree of Dermatitits Atopic manifestation is correlated with the score o f anxious scale on MMPI of the Dermatitis Atopic female patien ts in Dr. Soetomo Public Hospital Surabaya.   The method was analytical study with cr oss sectional approach, started from  Juli   2009 until Desember 2009. The datas was taken from policlinics of Skin and Venereal Desease Department of Dr. Sutomo Pu blic Hospital Surabaya. Fivety three samples were taken, while 7 of them were failed due to high invalid MMPI score.  The result showed that there was significant correlation between  the degree of Dermatitits Atopic manifestation with the score   of anxious scale on MMPI of the Dermatitis Atopic female pati ents. The correlation was medium to high.  Keywords: Dermatitis Atopic, Anxious Personality, MMPI

scholarly journals A Comparative Analytical Study of Fresh Honey Collected from Honey Comb of Apis Mellifera and Market Samples of Honey

2021 ◽  
pp. 175-181
Author(s):  
Bharat Rathi ◽  
Renu Rathi ◽  
Dhirajsingh Rajput ◽  
Anita Wanjari ◽  
Mujahid Khan
Keyword(s):  
Apis Mellifera ◽  
Analytical Study ◽  
Storage Condition ◽  
Honey Sample ◽  
Artificial Culture ◽  
Authentic Texts ◽  
Therapeutic Benefits ◽  
Three Samples ◽  
The Difference ◽  
Natural Honey

Honey is a natural product which was known to ancient seers of Ayurveda since Veda period. The nutritional and therapeutic benefits of honey were well known and also documented in authentic texts of Ayurveda. However the abundant availability of honey has gone decreasing since industrialization and deforestation. It has resulted in artificial culture and marketing of honey. The quality of such honey is matter of concern as it is easy to adulterate honey but is very hard to find out the difference between natural and adulterated honey. Considering this issue, present work has been planned to compare freshly collected natural honey and marketed samples of honey. For the comparative analytical study four different samples were collected. Three samples of three different pharmacies were procured from market (honey of branded Ayurvedic companies) and compared with collected honey sample from honeycomb of Apis mellifera. The collected four samples of honey have almost similar organoleptic characters i.e. colour, odour, taste and touch. Considerable differences are detected in physico-chemical analysis, nutritional value and HMF value. The observations are within normal range however the differences are suggestive of need of establishing quality control parameters based on source of honey, collection season, temperature and storage condition and also providing these details while labelling the samples. Finding of present study revealed that freshly collected natural honey have best desired attributes compared all three marketed samples.

scholarly journals PHARMACEUTICAL AND ANALYTICAL STUDY OF TRINETRA RAS – HERBO-MINERAL FORMULATION

2020 ◽  
pp. 1-10
Author(s):  
Nandurkar Vishal Marotrao ◽  
V. M. Ramteke ◽  
S.G. Jyotishi
Keyword(s):  
Physicochemical Parameters ◽  
Analytical Study ◽  
Classical Method ◽  
Analytical Studies ◽  
Three Samples ◽  
Standard Profile

Trinetraras is a Kharliya Rasayan mentioned in Yogratnakar for the treatment of Hridroga (Yogratnakar Uttarardha Hridroga Chikitsa 1,2). It consists of Shuddha Parad, Shuddhagandhak and Abhrakbhasma where Bhavanadravya is Arjuna bark decoction. Aim: Pharmaceutical and analytical study of Trinetraras. Materials and methods: Paradshodhan, Gandhakshodhan, Vajrabhrakshodhan, Dhanyabhraknirmana, preparation of Abhrakbhasma, preparation of Kajjali are the procedures required to be performed before the preparation of Trinetraras. Total 40 times Abhrak was subjected to Maransanskar in Gajaputa (40 puti Abhrakbhasma). Trinetraras can be prepared from Shuddha Parad, Shuddhagandhak and Abhrakbhasma, Arjuna bark decoction is needed for 21 Bhavana. Total three batches of Trinetra Ras were prepared as per the classical method mentioned in the reference. Observations and results: Prepared samples of Trinetraras and Abhrakbhasma were tested on the basis of organoleptic and physicochemical parameters. Along with Ayurvedic parameters modern parameters such as L.O.D., L.O.I., pH, conductivity, successive solubility, elemental assay of Hg, S and Fe, TLC, phenolic assay etc. were applied to the samples of Trinetraras. Conclusion: Analytical study of Trinetraras revealed the uniformity of the procedures in the three samples of Trinetraras, as evidenced by the observations of the analytical values of the three samples were not much variation found. Analytical profile showed the presence of the ingredients used. Data generated from pharmaceutical, analytical studies can be used to develop a preliminary standard profile for the formulation of Trinetra Ras.

Depression in General Practice:

1985 ◽  
Vol 147 (2) ◽  
pp. 113-119 ◽  
Author(s):  
L I. Sireling ◽  
E. S. Paykel ◽  
P. Freeling ◽  
B. M. Rao ◽  
S. P. Patel
Keyword(s):  
General Practice ◽  
Major Depression ◽  
Psychiatric Disorder ◽  
Diagnostic Criteria ◽  
The Other ◽  
Three Samples ◽  
Research Diagnostic Criteria

SummaryUsing multiple diagnostic and epidemiological criteria, three samples of general practice (GP) depressives were studied: those prescribed a new course of antidepressants, those given other treatment, and those missed by the GP. The majority of patients qualified as psychiatric cases on the PSE Index of Definition, the Bedford College Criteria, and the Research Diagnostic Criteria. Most satisfied diagnostic criteria for depression, or (fewer) anxiety. The disorders were relatively mild and often borderline on all three systems. Depressives given other treatment most often failed to meet diagnostic criteria. About half the antidepressant treated patients received RDC diagnoses of major depression. Among the other treatment sample, only one-fifth met these criteria, and half had non-depressive diagnoses. Most cases of depression treated by GPs satisfy criteria for psychiatric disorder, but tend to be relatively mild and borderline in quality.

Physico-chemical analysis of Haratala w.s.r. to its various Shodhana procedures

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Bandeppa Sangolgi ◽  
Ganapathi Rao ◽  
Sangameshwar Benne
Keyword(s):  
Chemical Analysis ◽  
Analytical Study ◽  
Operative Procedure ◽  
Pharmacological Properties ◽  
Arsenic Compounds ◽  
Single Drug ◽  
Physico Chemical ◽  
The Media ◽  
Pharmaceutical Processes

Kalpana is the process through which a substance can be transformed into the form of medicine according to the need. Samskaras are to be done for potentiating the drug or the formulation. Among all these pharmaceutical processes Shodhana is one of them. For a single drug many process of Shodhana have been mentioned. Arsenic compounds are being popularly used in Ayurveda therapeutics since centuries, Haratala being important among them. It is commonly used in treating the diseases like Sleshmaroga, Raktapitta, Vatarakta, Kustha etc. Haratala is called orpiment of yellow arsenic with two molecules of Arsenic and three molecules of Sulphur (AS2S3). Patra Haratala is Srestha and used for the present study. Haratala consumed without proper Shodhana shortens the life span, causes diseases of Kapha and Vata, Prameha, Santapa, Spotha, Snayu Sankocha. Hence Shodhana of Haratala is essential. There are different Medias explained in literature for Shodhana of Haratala. According to the media of purification the quality and pharmacological properties of Haratala will vary. Depending on the change in properties the therapeutic effect may also vary. The present study includes Shodhana of Patra Haratala as per Classical reference of Rasa Ratna Samucchaya where Shodana of Patra Haratala is done by Kushmanda Swarasa, Tila Kshara Jala and Churnodaka. Standard Operative Procedure of the process is done in the pharmaceutical study. The analytical study reveals the standards which can be given for Ashuddha Haratala and Shuddha Haratala of various Samples. The differences in the parameters reveal that there are some changes which give us the idea regarding role of a particular media in purification of a substance, where it adds some properties of the media used.

scholarly journals PHARMACEUTICAL AND ANALYTICAL STUDY OF ABHRAK BHASMA

AYUSHDHARA ◽  
2021 ◽  
pp. 2958-2963
Author(s):  
Nandurkar Vishal Marotrao
Keyword(s):  
Chronic Diseases ◽  
Standard Method ◽  
Analytical Study ◽  
Medicinal Herbs ◽  
Cardiac Diseases ◽  
Complex Structures ◽  
Chemical Parameters ◽  
Physico Chemical ◽  
Three Samples

Bhasma are the unique and important organometallic preparations used in Ayurveda Therapeutics. Bhasma are complex structures generally prepared by repeated incineration of metals and minerals with medicinal herbs decoction or juices. Abhrak Bhasma is an excellent cellular regenerator and nervine tonic. It is indicated in various chronic diseases such as tuberculosis, COPD and many types of cardiac diseases. Considering the principles of Ras-shastra and Bhaishajya Kalpana and also the importance of their standard method of preparation, it is decided to carry out pharmaceutical and analytical study of ‘Abhrak Bhasma’. Preparation of Abhrak Bhasma involves the procedures Vajrabhrak Shodhan, Dhanyabhrak Nirman and Maran of Abhrak. Prepared samples of Abhrak Bhasma tested on the basis of organoleptic and physico-chemical parameters. Prepared samples of Abhrakabhasma (AB-1, AB-2, AB-3) were Nishchandra, Sindurabha coloured, Sookshma, Rekhapurna, Sparshakomal (Mrudu, Shlakshna), Nirdhum and Niswadu. Along with Ayurvedic parameters modern parameters such as L.O.D., L.O.I., pH, conductivity, successive solubility, elemental assay of Fe2+ and Fe3+ etc. were applied to the samples of Abhraka Bhasma. Analytical study of Abhraka Bhasma revealed the uniformity of the procedures in the three samples of Abhraka Bhasma, as evidenced by the observations of the analytical values of the three samples were not much variation found.

scholarly journals A PHARMACEUTICO-ANALYTICAL STUDY OF AMRITADYA GUGGULU

AYUSHDHARA ◽  
2020 ◽  
pp. 2581-2585
Author(s):  
Swati Sharma ◽  
Manoj Sharma ◽  
Sudarshan Kumar Thakur
Keyword(s):  
Weight Loss ◽  
Analytical Study ◽  
Operative Procedure ◽  
Therapeutic Effects ◽  
Therapeutic Value ◽  
Commiphora Mukul ◽  
Pharmaceutical Processing ◽  
Crude Drugs ◽  
Removal Of Impurities

Aushadha Kalpana is prepared by different pharmaceutical processing applied to the crude drugs to get the desired therapeutic effects. Guggulu kalpana is one of them. Guggulu is the gummy resin of the Indian plant bdellium i.e. Commiphora mukul. Guggulu is always used after Shodhana to remove its impurities. So the process of Shodhana becomes imperative in different media. In addition to it, Shodhana of Guggulu in different media brings specific properties to Guggulu. Ayurvedic medicines are gaining increase in popularity worldwide for the treatment of various diseases in recent times. In the present study, Amritadya guggulu, one of the Guggulu preparation mentioned in Pidika, Bhagandara and Sthaulya like conditions in Chakkradatta, was prepared and analysed so as to prove the safety and efficacy of the drug. Aims and objectives: To develop standard operative procedure for preparation of genuine drug and to analyze the safety and purity of the drug. Material and Methods: Amritadya guggulu was prepared as per classical texts and analysed by using different parameters like organoleptic properties, physicochemical properties, TLC etc. Discussion and Conclusion: 50% weight loss was observed. The weight loss was due to removal of impurities present in the Guggulu and handling loss. Presence of low acid insoluble ash (1.08%) determines the presence of low adherent dirt as well as sand particles. Presence of low moisture content (loss on drying 6.2%) decreases decomposition and enhances the shelf life and therapeutic value of the drug. Hence it can be concluded that the pharmaceutical and analytical study confirm the authenticity and quality of the drug.

scholarly journals Concept of Kshara Nirmana Out of Kanji with Reference to Rasayansara- A Pharmaceutico-Analytical Study

2021 ◽  
pp. 259-266
Author(s):  
Mahesh S. Pawar ◽  
M. R. Pandya ◽  
A. N. Jayaprakash ◽  
Abhaya Kumar Mishra ◽  
Lopamudra Dash
Keyword(s):  
Analytical Study ◽  
Ph Value ◽  
Physicochemical Analysis ◽  
Pharmaceutical Product ◽  
Water Soluble ◽  
Special Method ◽  
Innovative Methods ◽  
Unique Method ◽  
Similar Preparation ◽  
Pharmaceutical Processes

Kanji (sour rice gruel) is an acidic fermented preparation mentioned in many of the Ayurveda classics for various purpose like therapeutic use, pharmaceutical processes etc. A special method of kanji preparation is mentioned in Rasaratnasamuchchaya commentary by Acharya Dattatreya Anant Kulkarni and similar preparation is also mentioned in Rasayansara book recommended for the Parada samskara (mercurial processes) with some difference in ingredients. Kshara (alkaline preparation/ alkali) is an important preparation mentioned in classics. In Rasayansara text, Acharya Shyamsundar Vaishyaji has described a unique method of Kshara nirmana out of the leftover material of the Kanji. This kind of innovative methods should be adopted to recycle the leftover waste matters. It will help in regenerate the new pharmaceutical product. Here an attempt has been done by preparing the kanji and the kshara out of its residue material as mentioned in Rasayansara. First Kanji was prepared as per the reference of Rasayansara book and the leftover after filtration was dried. The kshara was prepared out of this dried leftover. Organoleptic and physicochemical analysis of the prepared kshara was done. The average yield of obtained kshara was 4.88%. The moisture content of the final product found very less while total ash value found on higher side. The pH value suggests its alkaline nature. It shows good solubility in various solvents and good water-soluble extractive value. Exploration of such innovative procedures where waste stuff is been recycled should be increased in present time.

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