Perbedaan Kadar Brain Derived Neurotropic Factor Neonatus Dari Ibu Hamil Normal Dan Anemia Defisiensi Besi

2018 ◽  
Vol 3 (3) ◽  
pp. 568
Author(s):  
Ainal Mardiah ◽  
Arni Amir ◽  
Andi Friadi ◽  
Ellyza Nasrul

<p><em>Iron deficiency anemia is anemia caused by iron deficiency in the blood. Maternal iron deficiency affects the low iron reserves in neonates </em><em>and it also influences on </em><em>Brain Derived Neurotropic Factor (BDNF) </em><em> which affects cognitive function.</em><em> </em><em>The purpose of this study was to determine the difference mean of BDNF in neonates from normal pregnant women and pregnant women with iron deficiency. </em><em>The design of this research was Cross Sectional</em><em> </em><em>design. This research was conducted in Community Health Center of Lubuk  Buaya, Ambacang Community Health Center, Community Health Center of Ikur Koto Health Center and Biomedical Laboratory of Andalas University on February 2017 to April 2018. There were 42 pregnant women was selected as sample e of this research. The samples were chosen by Consecutive Sampling. Then, the sample is divided into two groups: normal pregnant women and pregnant women with iron deficiency anemia. BDNF are examined by the ELISA. Next, the data were analyzed by using T test. The levels of BDNF neonates in normal pregnant group was 3.65(ng/ml) and the anemia pregnant group was 1.74(ng/ml) (p &lt;0.05). There was significant difference of BDNF levels in neonates from normal pregnant women and pregnant women with iron deficiency anemia. </em><em>The conclusion of this study is there is a difference of average BDNF in neonates from normal pregnant women and pregnant women with iron deficiency.</em></p><p> </p><p>Anemia defisiensi besi adalah anemia yang disebabkan karena kekurangan zat besi dalam darah. Defisiensi besi  maternal berdampak pada rendahnya cadangan besi pada neonatus dan berdampak terhadap ekspresi Brain Derived Neurotropic Factor (BDNF) yang berpengaruh pada fungsi kognitif. Tujuan penelitian ini adalah untuk mengetahui perbedaan rerata kadar BDNF pada neonatus dari ibu hamil normal dan ibu hamil defisiensi besi. Desain penelitian ini adalah Cross Sectional. Penelitian dilakukan di Puskesmas Lubuk Buaya, Puskesmas Ambacang, Puskesmas Ikur Koto dan Laboratorium Biomedik Universitas Andalas pada bulan Februari 2017 – Juli 2018. Sampel Penelitian adalah ibu hamil sebanyak 42 orang yang dipilih secara Consecutive Sampling, sampel dibagi menjadi dua kelompok yaitu ibu hamil normal dan ibu hamil anemia defisiensi besi. BDNF diperiksa dengan metode ELISA. Data dianalisa menggunakan uji T test. Kadar BDNF neonatus pada ibu kelompok normal adalah 3,65(ng/ml) dan kelompok ibu anemia adalah 1,74(ng/ml) (p&lt;0,05). Terdapat perbedaan bermakna kadar BDNF pada neonatus dari ibu hamil normal dan ibu anemia defisiensi besi. <em></em></p>

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Emy Huriyati ◽  
Tri Ratnaningsih ◽  
Abdul Wahab ◽  
Arta Farmawati ◽  
Nur Imma Fatimah Harahap ◽  
...  

ABSTRAK Fokus Dinas Kesehatan Kabupaten Sleman untuk penanggulangan anemia dewasa ini bukan hanya pada ibu hamil saja, melainkan sudah dimulai dari remaja puteri, jauh sebelum mereka hamil. Langkah pemerintah dalam menanggulangi anemia dengan adanya suplementasi besi dikhawatirkan tidak tepat sasaran. Sejauh ini deteksi anemia oleh petugas puskesmas hanya sebatas pemeriksaan haemoglobin saja dan kejadian anemia yang terdeteksi masih bersifat general, tidak spesifik anemia defisiensi besi. Subjek dalam kegiatan ini adalah petugas puskesmas meliputi dokter, ahli gizi dan ahli teknologi laboratorium medis yang diambil secara purposive sampling. Metode yang diterapkan dalam kegiatan ini adalah pelatihan dengan rangkaian kegiatan yaitu penyuluhan dengan pre-test dan post-test, tutorial kasus, dan praktikum. Analisis data hasil kegiatan menggunakan uji paired t-test antara nilai pre-test dan post-test. Uji statistik dikatakan signifikan bila p-value kurang dari 0,05. Total peserta yang mengikuti kegiatan adalah 71 orang dari target awal 75 orang (persentase kedatangan= 94,67%). Pelatihan terkait anemia defisiensi besi untuk petugas puskesmas dapat meningkatkan tingkat pemahaman sebesar 32,82 poin (p<0,0001), yang merupakan delta kenaikan nilai pre-test dan post-test. Pemilihan metode untuk kegiatan pelatihan dirasa sudah tepat dengan pertimbangan hasil evaluasi kegiatan menunjukkan sebagian besar peserta kegiatan menilai metode pelatihan efektif atau sangat efektif (74,7%). Program pelatihan dapat meningkatkan pemahaman petugas puskesmas di Kabupaten Sleman terkait anemia defisiensi besi.KATA KUNCI pelatihan; puskesmas; pengetahuan; anemia defisiensi besi ABSTRACT The focus of the Sleman District Health Office in the prevention of anemia is not only on pregnant women anymore as it currently involves young women, long before they become pregnant. The government's step in overcoming anemia with iron supplementation is argued to fail to hit the target. So far the detection of anemia by health center officials is only limited to hemoglobin examination, indicating that the detection of anemia is still general and not specific to iron deficiency anemia. The subjects of this study were community health center staffs including doctors, nutritionists and medical laboratory technology experts who were picked by purposive sampling. The methods used were training with a series of activities: education with pre-test and post-test, case tutorials, and practicum. Paired t-test was performed to compare the difference of value between pre-test and post-test. P-value of less than 0.05 was considered statistically significant. The total participants who took part in the activity were 71 people from the initial target of 75 people (percentage of arrivals = 94.67%). Training related to iron deficiency anemia for health center officers can increase the level of understanding by 32.82 points (p <0,0001). The methods chosen for training activities were considered appropriate with around three-quarters (74,7%) of the participants rated the training method effective or very effective. The training program can improve the understanding of health center staff in Sleman Regency regarding iron deficiency anemia.KEYWORDS training; community health center; knowledge; iron deficiency anemia 


2019 ◽  
Vol 6 (1) ◽  
pp. 49
Author(s):  
Hary Yadi ◽  
Asmarita Jasda

<p>Pregnancy leads to increased energy metabolism, hence the need for energy and other nutrients increases during pregnancy. Increased energy and nutrients are needed for growth and development of the fetus, the increase in the amount of the uterus, changes in the composition and metabolism of the mother's body. If  levels of iron in the body of pregnant women is less, then there will be a condition called anemia. That's because iron is an essential microelement for the body. This substance is especially needed in hemopoiesis (blood formation), ie in the synthesis of hemoglobin. The purpose of this study was  to determine Knowledge of Pregnant Women About Iron Deficiency Anemia and Family Role With Compliance In Consuming Iron Tablet in health center . This study was a quantitative research, analytical, with cross sectional study subjects all mothers who have antenatal and get a tablet Fe in Tanjungpinang health center  based on data consist of 40 respondents. The result of this study was significat relationship between knowledge of pregnant women to iron deficiency anemia with Compliance Consuming Tablet iron  show the value of p 0814, the p-value is greater than the p value 0:05 was shows that no have correlation between knowledge of pregnant women about iron deficiency anemia with Compliance Consuming Iron Tablets. Family Role in monitoring drinking iron tablet  with Compliance Consuming Iron Tablets shows the value of p 0.00 is smaller than the value of α 0.05. This shows that there is a relationship between family role in monitoring drinking iron tablet with compliance consuming iron tablet. This study  indicated to increase Knowledge Level Of a Person On Iron Deficiency Anemia  Not Consume The Influence Behavior Of Iron Tablet  But Can Improve The Role Of Family In Compliance With Pregnant Women Eat Iron Tablet.</p>


Author(s):  
Mohammad Zulkarnain ◽  
Rizka Muliani ◽  
Rico Januar Sitorus ◽  
Nurlaili Nurlaili

Pregnant women are at risk for iron deficiency anemia especially pregnant women in malaria-endemic areas. This study aimed to analyze the profile of iron in the third trimester pregnant women with iron deficiency anemia in co-endemic area of Bengkulu city. This study was cross-sectional study with a total sample of 66 pregnant women who met the inclusion criteria. Examination profile of iron in pregnant women is done by taking blood specimen through the vena cubity. Profile iron includes examination sTfR levels, hepcidin, transferrin were examined by ELISA. Determination of iron deficiency anemia is based on the results of Hb, serum iron and TIBC. The results showed 39.4% of pregnant women experience iron deficiency anemia. There is an average difference between hepcidin levels with the incidence of iron deficiency anemia (p-value 0.031). Based on binary logistic regression analysis profile iron with irondeficiency anemia in pregnant women, hepcidin levels are predictors factors on the incidence of iron deficiency anemia (p-value 0.000, 95% CI .296-.709).


2017 ◽  
Vol 24 (3) ◽  
pp. 37-44
Author(s):  
Santoso Ujang Effendi ◽  
Buyung Keraman ◽  
Andrek Sarnandes

The impact of the incidence of anemia in pregnant women who have less knowledge during pregnancy are abortion, preterm labor, fetal and uterine disorders, low birth weight (LBW), and high maternal mortality. This study aimed to study the relationship between the level of knowledge with the incidence of anemia in pregnant women at Tanjung Kemuning Community Health Center Kaur District. This type of research was Descriptive Correlation and the design used was Cross Sectional. The data in this study used the primary data obtained by distributing questionnaires. The population in this study was all pregnant women who checked pregnancy and did not check their pregnancy at Tanjung Kemuning Community Health Center of Kaur Regency from January to June 2016 as many as 66 pregnant women. Sampling technique are Total Sampling and obtained sampel counted 35 respondents. Data analysis was done by univariate and bivariate analysis with Chi-Square test and to know closeness using Contingency Coefficient (χ2) statistic test. The result of the research showed that there were 14 respondents (40.0%) of good knowledge, and 19 respondents (54,3%) did not experience anemia. There was a significant relationship between knowledge with the incidence of anemia in pregnant women in working area of Tanjung Kemuning Community  Health  Center Kaur District with a close category. Suggestion for Tanjung Kemuning  Community  Health Center Kaur District                   to increase the intake of iron nutrition in pregnant women by doing  health promotion about  anemia  and giving  iron  tablets  to pregnant  woman. Keywords : anemia, knowledge, pregnant women


Author(s):  
Dewi Kartika Sari ◽  
◽  
Putri Wahyu Wigati ◽  

ABSTRACT Background: Anemia is a pathologic condition produced by a decrease in red blood cell mass or a decrease in the amount of hemoglobin. The initial survey carried out in the Tiron Puskesmas work area in the June-July 2019 period was still a high incidence of anemia in the Tiron Puskesmas Kediri Regency work area (60%). This study aimed to analyze factors affecting anemia in pregnant women with second and third trimester of pregnancy at tiron community health center, Kediri district, East Java. Subjects and Method: A cross sectional study was carried out at Tiron community health center, Kediri, East java, from June to July 2020. A sample of 49 2nd and 3rd trimesters of pregnant women was selected by purposive sampling. The dependent variable was anemia. The independent variables were age, iron tablet intake, ANC visit. The data were collected by questionnaire and analyzed by a multiple logistic regression. Results: Anemia in pregnant women decreased with older age (OR= 0.08; 95% CI = 0.01 to 1.20; p = 0.068). Anemia in pregnant women increased with irregular iron tablet intake (OR= 18.45; 95% CI = 2.77 to 123.10; p = 0.003) and irregular ANC visit (OR = 1.85; 95% CI = 1.05 to 38.18; p = 1.87). Conclusion: Anemia in pregnant women decreases with older age. Anemia in pregnant women increases with irregular iron tablet intake and irregular ANC visit. Keywords: anemia, hemoglobin levels, pregnant women Correspondence: Dewi Kartika Sari. Faculty of Health Sciences Universitas Kadiri. Jl. Selomangleng No 1, Kediri. Email: [email protected] DOI: https://doi.org/10.26911/the7thicph.03.50


2012 ◽  
Vol 19 (02) ◽  
pp. 155-158
Author(s):  
SAEED SIDDIQUI ◽  
ATIF SITWAT HAYAT ◽  
M. KHALID SIDDIQUI ◽  
Naila Atif ◽  
Hamayun Shah

Objectives: To estimate the frequency of iron deficiency anemia in a sample of population of pregnant women residingpermanently at high altitude of ≥5000 feet in different areas of district Abbottabad. Study Design: Cross sectional Study. Place & duration ofStudy: Northern Institute of Medical Sciences Abbottabad: From 17 August 2009 to 15 June 2010. Subjects and Methods: This study wascarried out on hundred pregnant women residing permanently at an altitude of ≥5000 feet above sea level in district Abbottabad. The agerange was fixed to 15-45 (child bearing age ) years. Suspected study participants having anemia were tested for iron status by serum ferritintest. Pregnant women having both anemia and iron deficiency were labeled as patients of Iron deficiency anemia. Results: The age range was15-41 years with a mean of + / - SD of 28.13 + / - 6.61. All women were of low and middle socioeconomic class with 74 % illiteracy. 60 % of womenhad birth spacing of two or less than two years. 64 % of pregnant women had three children. Anemia was detected in 74 % (X2 =9.42 p > 0.05),iron deficiency in 66 % (X2 = 14.76 p <0.01) and iron deficiency anemia in 60 % (X2 = 13.56 p < 0.01). Conclusions: High altitude residentpregnant women remain at high risk of developing iron deficiency anemia because of illiteracy, poverty and ignorance. With adequate nutritionand health education the problem can be addressed effectively.


2020 ◽  
Author(s):  
Jing Tan ◽  
Guolin He ◽  
Yana Qi ◽  
Hongmei Yang ◽  
Yiquan Xiong ◽  
...  

Abstract Background: The current evidence about anemia and iron deficiency anemia (IDA) during pregnancy remains elusive in China. The purpose of this study is to investigate the prevalence of anemia and IDA and their risk factors in Chinese pregnant women.Methods: A nationwide cross-sectional survey of pregnant women was conducted during their antenatal visits. Using a multi-stage sampling method, 24 hospitals from 16 provinces across China were selected. Structured questionnaires were administered to collect information from participants and to extract clinical data from electronic medical records. Mixed-effects logistic regression models were performed to determine the risk factors associated with anemia and IDA.Results: In total, 12,403 pregnant women were enrolled, including 1,018 (8.2%) at the first trimester, 3,487 (28.1%) at the second, and 7,898 (63.7%) at the third. Overall, 19.8% of women were diagnosed with anemia and 13.9% were diagnosed with IDA. The prevalence of anemia and IDA varied among regions and increased by gestational month, peaking at the eighth gestational month (24.0% for anemia and 17.8% for IDA). Pregnant women at advanced stage of gestation, non-local residents, multiple gestations, multiparity, pre-pregnancy underweight, and those experiencing severe nausea or vomiting during pregnancy, were associated with higher risks of anemia and IDA.Conclusions: The prevalence of anemia and IDA during pregnancy are similar to those from developed countries and vary across regions in China.


2020 ◽  
Author(s):  
Jing Tan ◽  
Guolin He ◽  
Yana Qi ◽  
Hongmei Yang ◽  
Yiquan Xiong ◽  
...  

Abstract Background: The current evidence about anemia and iron deficiency anemia (IDA) during pregnancy remains elusive in China. The purpose of this study is to investigate the prevalence of anemia and IDA and their risk factors in Chinese pregnant women.Methods: A nationwide cross-sectional survey of pregnant women was conducted during their antenatal visits. Using a multi-stage sampling method, 24 hospitals from 16 provinces across China were selected. Structured questionnaires were administered to collect information from participants and to extract clinical data from electronic medical records. Mixed-effects logistic regression models were performed to determine the risk factors associated with anemia and IDA.Results: In total, 12,403 pregnant women were enrolled, including 1,018 (8.2%) at the first trimester, 3,487 (28.1%) at the second, and 7,898 (63.7%) at the third. Overall, 19.8% of women were diagnosed with anemia and 13.9% were diagnosed with IDA. The prevalence of anemia and IDA varied among regions and increased by gestational month, peaking at the eighth gestational month (24.0% for anemia and 17.8% for IDA). Pregnant women at advanced stage of gestation, non-local residents, multiple gestations, multiparity, pre-pregnancy underweight, and those experiencing severe nausea or vomiting during pregnancy, were associated with higher risks of anemia and IDA.Conclusions: The prevalence of anemia and IDA during pregnancy are similar to those from developed countries and vary across regions in China.


2019 ◽  
Vol 4 (3) ◽  
pp. 153
Author(s):  
Irma Rismayanti Amanah ◽  
Irma Rismayanti Amanah

Introduction: The prevalence of iron deficiency anemia in pregnant women in the world according to WHO ranges from 35-37%, similarly found in pregnant women in Indonesia, Riskesdas in 2013 reported a prevalence of 37.1%. Although the treatment of iron deficiency anemia for pregnant women has been entered into ANC treatment, the prevalence has not given the expected thing. However, in Sumedang District, the prevalence of anemia in pregnant women in 2016 lower, 9.69%, pharmacoepidemiological data related to the use of blood boosting vitamins in Jatinangor is still limited. this research was conducted in Jatinangor as target area of Universitas Padjadjaran.Objective: To know the blood Enhancer supplement consumption practices on pregnant women in Jatinangor.Methods: A cross-sectional study was carried out in July-August 2018 with pregnant women in Jatinangor, based on the formula large sample descriptive, sampling conducted in 12 villages and subjects were selected consecutively. Data analysis was carried out descriptively interview data using a closed questionnaire.Results: within research recorded 532 pregnant woman, 110 pregnant women are eligible to participate. It was found 96 pregnant women taking blood boosting vitamins, 69 Taking folicacid, 27 taking irontablets, 15 consuming B12, 2 consuming B6. It was found who did not take vitamins, 14 pregnant women for several reasons, 8 people felt healthy, 3 people felt the complaints were mild so it does not require vitamins, 4 others were afraid of the side effects.Conclusion: Most of the respondents already know how to consume suplments


2017 ◽  
Vol 3 (3) ◽  
pp. 102-106
Author(s):  
Anita Rosanty ◽  
Reni Yunus

Background: Insufficient hemoglobin levels are one of the most vulnerable health problems during pregnancy. Hemoglobin levels less than 11 g/dL indicate anemia in pregnant women. However, it is assumed that there is a difference of hemoglobin levels between pregnant women in coastal and plateau areas. Objective: To compare the hemoglobin levels in pregnant women who live in the coastal and plateau areas in the working area of the Community Health Center of Mata, Kendari. Methods: This was an observational analytic research with cross sectional approach, conducted in May-June 2014. There were 38 pregnant women using quota sampling, divided into 19 respondents in coastal areas and 19 respondents in plateau areas. Blood sampling was performed in each respondent, and categorized into mild, moderate, and severe anemia. Data were analyzed using chi-square test. Results: The proportion of pregnant women with anemia in the working area of the Community Health Center of Mata was 94.74%. Chi-square test showed p-value 0.307 (0.05). Conclusion: There was no significant difference in hemoglobin levels in pregnant women in coastal and plateau areas in the working area of the Community Health Center of Kendari district. 


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