scholarly journals EFEKTIFITAS MODALITAS LATIHAN TERHADAP PENURUNAN NYERI PADA LANSIA DENGAN OSTEOARTRITIS LUTUT DI KOTA MALANG

2021 ◽  
Vol 2 (2) ◽  
pp. 39-49
Author(s):  
Sri Sunaringsih Ika Wardojo ◽  
Rakhmad Rosadi ◽  
Suci Amanati ◽  
Yudha Wahyu Putra
Keyword(s):  
T Test ◽  
Home Exercise ◽  
Cross Sectional ◽  
Backward Walking ◽  
Strengthening Exercise ◽  
Paired T Test

Osteoartritis merupakan penyakit sendi yang memiliki ciri khas yaitu terjadinya degradasi dari tulang rawan sendi. Terapi non farmakologis yang juga disarankan untuk penderita osteoartritis lainnya exercise yang di lakukan pada sendi lutut. Jenis exercise antara lain yang dapat dilakukan adalah home exercise, ataupun strengthening exercise yang berarti latihan penguatan yang meliputi quadriceps dan hamstring exercise, serta aerobik exercise seperti berjalan (forward walking or backward walking), bersepeda dan berenang. Penelitian ini bertujuan untuk menguji secara empiris perbandingan efektifitas pemberian terapi Fisioterapi terhadap penurunan nyeri pasien lansia dengan osteoartritis lutut. Penelitian ini memiliki desain cross-sectional dengan 30 partisipan yang merupak pasien OA lutut di Puskesmas Dinoyo, RST Soepraoen, dan RS UMM dan telah memenuhi kriteria inklusi. Semua partisipan kemudian dibagi menjadi Grup I (menerima terapi latihan selama 6 minggu), dan Grup II ( menerima terapi latihan selama 2 minggu). Instrumen penelitian yang digunakan adalah kuesioner VAS dan jenis analisa data yang dilakukan adalah uji paired T test dan independent T-test. Berdasarkan hasil uji paired T test  masing-masing untuk Grup I dan Grup II diketahui bahwa terdapat perbedaan yang signifikan antara tingkat nyeri responden antara sebelum dan setelah dilakukan terapi latihan pada masing-masing grup. Selanjutnya ketika dibandingkan outcome terapi yang diberikan pada Grup I dan Grup II diketahui bahwa terdapat perbedaan yang signifikan antara kedua Grup, dimana Grup II relatif memiliki tingkat penurunan nyeri yang lebih baik dibandingkan dengan responden pada Grup I yang menerima terapi latihan selama 6 minggu

Visualoutcome Pada Pasien Retinopati Diabetik Pasca Operasi Pars Plana Vitrektomi Di Rumah Sakit Pertamina Bintang Amin Provinsi Lampung Tahun 2020/2021

2021 ◽  
Vol 1 (4) ◽  
pp. 394-403
Author(s):  
Rahmat Syuhada ◽  
Toni Prasetya ◽  
Ade Utia Detty ◽  
Merryshol Okhi
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Pars Plana Vitrectomy ◽  
T Test ◽  
P Value ◽  
Cross Sectional ◽  
Pars Plana ◽  
Vitrectomy Surgery ◽  
Paired T Test ◽  
Diabetes Melitus

ABSTRACT: VISUAL RESULTS OF DIABETES RETINOPATHY PATIENTS POST PARS PLANA VITRECTOMY OPERATION AT PERTAMINA BINTANG AMIN HOSPITAL Background: Diabetic retinopathy is a neovascular complication that is very specific for type 1 diabetes and type 2 diabetes. Based on data according to Basic Health Research (RISKESDAS) in 2018, diabetes mellitus in 2013 reached 1.5% of patients with diabetes, and is increasing. to 2.0% in 2018. Treatment of diabetes mellitus patients with complications of diabetic retinopathy by performing pars plana vitrectomy surgery which is anoperative management that can improve eye visual or restore visual fuction. Research Objectives: To determine the visual outcome in diabetic retinopathy patients after pars plana vitrectomy surgery at Pertamina Bintang Amin Hospital, Lampung Province in 2020.Research Methods: This type of research was cross -sectional. Sampling was done by total sampling. Bivariate data analysis using Paired T-Test.Results: Statistical analysis using Paired T-Test showed the p-value for visualoutcome analysis in diabetic retinopathy patients before and after pars plana vitrectomy surgery was 0.000 (p-value <0.05).Conclusions: There are significant changes in diabetic retinopathy patients visualoutcome before pars plana vitrectomy surgery and after pars plana vitrectomy surgery at Pertamina Hospital Amin Star Lampung Province 2020. Keywords: Diabetic retinopathy, pars plana vitrectomy operation, Visualoutcome INTISARI: VISUALOUTCOME PADA PASIEN RETINOPATI DIABETIK PASCA OPERASI PARS PLANA VITRECTOMY DI RUMAH SAKIT PERTAMINA BINTANG AMIN  Latar Belakang: Retinopati diabetik adalah komplikasi neovaskular yang sangat spesifik untuk diabetes tipe 1 dan diabetes tipe 2. Berdasarkan data menurut Riset Kesehatan Dasar (RISKESDAS) pada tahun 2018, penyakit diabetes melitus di tahun 2013 mencapai 1,5% pasien pengidap diabetes, dan meningkat menjadi 2,0% pada tahun 2018. Penanganan pada pasien diabetes melitus dengan komplikasi retinopati diabetik diantaranya adalah dengan dilakukannya operasi pars plana vitrektomi yang merupakan penatalaksanaan operatif yang dapat memperbaiki visus mata atau memulihkan fungsi penglihatan . Tujuan Penelitian: Untuk mengetahui visualoutcome pada pasien retinopati diabetik pasca operasi pars plana vitrektomi di Rumah Sakit Pertamina Bintang Amin Provinsi Lampung Tahun 2020.Metode Penelitian: Jenis penelitian ini adalah potong silang (Cross-sectioal). Pengambilan sampel dilakukan secara total sampling. Analisis data bivariat dengan Paired T-Test.Hasil Penelitian: Analisis statistik menggunakan uji Paired T-Test menunjukkan p-value untuk analisa visualoutcome pada pasien retinopati diabetic sebelum dan sesudah operasi operasi pars plana vitrektomi sebesar 0,000 (p-value < 0,05).Kesimpulan: Terdapat perubahan yang signifikan pada visualoutcome pasien retinopati diabetik sebelum operasi pars plana vitrektomi dan sesudah operasi pars plana vitrektomi di Rumah Sakit Pertamina Bintang Amin Provinsi Lampung Tahun 2020. Kata Kunci: Retinopati Diabetik, Operasi Pars Plana Vitrektomi, Visualoutcome

scholarly journals Analisis Pengaruh Penggunaan Depot Medroxyprogesterone Acetate Terhadap Kenaikan Berat Badan Akseptor di Puskesmas Perumnas II Pontianak

2020 ◽  
Vol 7 (2) ◽  
pp. 149
Author(s):  
Nurmainah Nurmainah ◽  
Sri Wahdaningsih ◽  
Syaazaratul Qamelia Innas
Keyword(s):  
Weight Gain ◽  
Medroxyprogesterone Acetate ◽  
Sampling Technique ◽  
T Test ◽  
Public Health Care ◽  
Cross Sectional ◽  
Test Analysis ◽  
Purposive Sampling ◽  
Depot Medroxyprogesterone Acetate ◽  
Paired T Test

Kontrasepsi suntik merupakan salah satu kontrasepsi hormonal yang masih menjadi pilihan akseptor dalam mengatur kehamilan. Namun demikian, penggunaan kontrasepsi suntik Depot Medroxyprogesterone Acetate (DMPA) diketahui dapat meningkatkan berat badan selama pemakaian enam (6) bulan atau lebih. Tujuan penelitian ini dilakukan untuk menganalisis pengaruh penggunaan DMPA terhadap kenaikan berat badan akseptor. Penelitian ini merupakan penelitian observasional dengan rancangan penelitian potong lintang (cross sectional) yang bersifat analitik. Populasi dalam penelitian ini adalah seluruh akseptor baru suntik DMPA di Puskesmas Perumnas II Pontianak pada bulan Januari 2018 hingga Maret 2019. Variabel dari penelitian ialah usia, pekerjaan, paritas, dan kenaikan berat badan. Analisis dilakukan dengan menggunakan analisis paired t-test. Teknik pengambilan sampel yang digunakan ialah purposive sampling. Jumlah sampel yang memenuhi kriteria inklusi dan ekslusi sebanyak 81 akseptor. Dari hasil penelitian ini diperoleh bahwa sebagian besar akseptor berusia 20-35 tahun (71,6%), bekerja sebagai ibu rumah tangga (97,5%), mempunyai 2 anak atau lebih (77,8%), dan memiliki kenaikan berat badan 0-2 kg (44,4%). Berdasarkan hasil analisis paired t-test bahwa penggunaan suntik KB 3 bulan (DMPA) memiliki pengaruh terhadap kenaikan berat badan akseptor dengan nilai p=0,001. Kesimpulan dari penelitian ini bahwa terdapat pengaruh penggunaan DMPA terhadap kenaikan berat badan akseptor. Injectable contraception is a hormonal contraceptive used by acceptors in regulating pregnancy. However, the use of Depot Medroxyprogesterone Acetate (DMPA) is known to increase body weight after six months of use or more.. The purpose of this study was to analysis the effect of using DMPA on weight gain. This study was an observational study with cross sectional analytic study design. The population in this study were all new acceptors who used DMPA at the Perumnas II Pontianak Public Health Care in January 2018 to March 2019. Variables from the study were age, occupation, parity, and weight gain. Analysis was performed using paired t-test analysis. The sampling technique used was purposive sampling, where the number samples that met the inclusion and exclusion criteria were 81 acceptors. The results showed that most of the acceptors were aged 20-35 years (71,6%), work as housewives (97,5%), had 2 or more children (77,8%), and gained weight 0-2  kg (44,4%). Based on the results of paired t-test analysis, the use of DMPA has an effect on the acceptor’s weight gain with a value of p = 0.001. The conclusion of this study is that there is an effect of the use of DMPA on acceptor weight gain.Keywords: Acceptors, DMPA, weigt gain 

scholarly journals Comparing Bender-Gestalt Test and Quantitative Electroencephalography for Brain Trauma Diagnosis in Depressive and Attention Deficit Hyperactivity Disorders

2021 ◽  
Vol 8 (3) ◽  
pp. 144-148
Author(s):  
Samaneh Shakeri ◽  
Reza Bidaki ◽  
Hamid Mirhosseini ◽  
Mina Kiani
Keyword(s):  
Depressive Disorder ◽  
Brain Damage ◽  
Attention Deficit ◽  
Cross Sectional Study ◽  
T Test ◽  
Quantitative Electroencephalography ◽  
Cross Sectional ◽  
Attention Deficit Hyperactivity Disorders ◽  
Bender Gestalt Test ◽  
Paired T Test

Background: Some experts assert there is an association between traumatic brain injury and cognitive impairments such as attention deficit hyperactivity disorder (ADHD) and depressive disorder. Furthermore, children and adults with ADHD struggle with focusing, organizing tasks, and feeling restless. They might experience sadness, guilt, irritability, low self-confidence and helplessness. In this regard, ADHD and depressive disorder occasionally occur together. We aimed to compare the clinical application of the Bender-Gestalt test (BGT) and electroencephalography in screening brain damage in the patients with the mentioned disorders. Methods: This was a cross-sectional study to assess diagnostic accuracy. Eighty patients with depression (n=35) and ADHD (n=45) resulting from brain damage aged 10-35 years who had been referred by the psychologist or psychiatrist to Imam Hossein Clinic in Yazd. Both the BGT and quantitative electroencephalography (QEEG) results existed in their files. Patients with any serious medical, other psychiatric disorders or history of drug dependency were excluded. Paired t test was used to analyze the differences. Results: The brain damage score was different in the two tests. Based on the paired t test, the BGT was a more valid screening test. Also, the score of the two tests were different in the depression and ADHD mean scores (P<0.05). Conclusion: BGT was a more reliable tool compared to QEEG for diagnosing brain damage within the patients with the mentioned disorders.

scholarly journals PERBEDAAN INDEKS MASSA TUBUH PADA AKSEPTOR KB SUNTIK 1 DAN 3 BULAN

2017 ◽  
Vol 2 (3) ◽  
pp. 270
Author(s):  
Anne Rufaridah ◽  
Kurnia Putri ◽  
Ayuro Cumayunaro ◽  
Sidaria Sidaria
Keyword(s):  
Side Effects ◽  
Demographic Data ◽  
Mean Value ◽  
T Test ◽  
Weight Changes ◽  
Cross Sectional ◽  
Weight Gains ◽  
The Difference ◽  
Injectable Contraceptives ◽  
Paired T Test

<p><em>Injection method is the most widely used contractive because the usage are safe, simple, effective and practice as long as the high these acceptor it is certaily followed by complain of side effects such weight changes, the purpose study uses an analitic with cross sectional approach. The population where 188 people where the acceptor injection contraceptives the sample amounted to 33 clients in each acceptor of 1 and 3 month the data collection are demographic data and questionaire sheet and it was analyzed by paired t-test and independent t-test. The result of this study showed that most of then were totally weight gains wich the difference mean value between pretest and postest the acceptor KB of 1 month is 3,71 kg/m² the while a mean value of the acceptor 3 months is 5,10 kg/m² those means there were a change of impact on weight gains amoung the acceptor KB of 1 and 3 months. While the value of independent t-test showed p=0,021 (p&gt;0,05). Baced on these results it can be concluded that there were significantly  difference wight changes between and acceptor injectable contraceptives 1 and 3 month expecte.</em></p>

scholarly journals PENYULUHAN KESEHATAN TENTANG HIV/AIDS TERHADAP PENGETAHUAN DAN SIKAP PADA SISWA SMA NEGERI PARONGPONG DESA CIHANJUANG KECAMATAN BANDUNG BARAT

2019 ◽  
Vol 5 (1) ◽  
pp. 56-62
Author(s):  
Imanuel Sri Mei Wulandari ◽  
Irawati Namah
Keyword(s):  
T Test ◽  
Cross Sectional ◽  
Paired T Test ◽  
Hiv Aids

Lebih dari setengah infeksi HIV didunia ditemukan pada usia 15-19 tahun, dan mayoritas remaja terinfeksi karena hubungan seksual. Data Penularan HIV/AIDS pada remaja di Jawa Barat, dari jumlah penduduk Jawa Barat yang berusia 10-24 tahun, sebesar 11.358.704 atau 26,60% adalah remaja. Penelitian ini bertujuan untuk mengetahui pengetahuan dan sikap siswa SMA  tantang HIV/AIDS di SMA Negeri Parompong Jawa Barat . etode penelitian ini secara survey. Rancangan penelitian deskriptif pre- post tanpa kontrol dengan pendekatan cross sectional. Populasi kelas II SMA yang menjadi sampel  sebanyak 86 orang yang terdiri dari IPA 34 siswa  dan IPS 52 siswa . Instrumen penelitian untuk mengukur pengetahuan dan sikap  berupa kuesioner tertutup dengan skala Guttman Instrument untuk perngukuraan tingkat pengetahuan dan sikap tentang HIV/AIDS. Analisa data dilakukan untuk mengetahui hubungan antara masing- masing variabel bebas (independent) dan variabel terikat (dependent) dengan uji paired t-test. Terdapat pengaruh yang signifikan sebelum dan sesudah dilakukan penyeluhan kesehatan dengan nilai p = 0,000. Dalam mencari informasi tentang HIV/AIDS diharapkan remaja lebih selektif baik melalui media cetak maupun media elektronik. Informas HIV/AIDS sebaiknya diberikan sejak dini, agar pengetahuan remaja tentang HIV/AIDS lebih baik. Kata Kunci: HIV AIDS, pengetahuan, remaja

scholarly journals THE EFFECT OF ERYTHROPOIETIN DOSE PHASE OF CORRECTION AS DRUG-RELATED PROBLEMS TO TARGET LEVEL OF HEMOGLOBIN IN REGULAR HEMODIALYSIS PATIENTS

2018 ◽  
Vol 11 (5) ◽  
pp. 151
Author(s):  
Luthvia Luthvia ◽  
Urip Harahap ◽  
Syafrizal Nasution
Keyword(s):  
Test Sample ◽  
Hemoglobin Level ◽  
T Test ◽  
Drug Related Problems ◽  
Registration Form ◽  
Chi Square ◽  
Cross Sectional ◽  
Before And After ◽  
Chi Square Test ◽  
Paired T Test

Objectives: This research aims to know the effect of drug-related problems (DRPs)-related doses against the target hemoglobin levels in hemodialysis (HD) patients in the regular phase of the correction given the therapy of erythropoietin on H. Adam Malik Medan.Methods: This research was by the cross-sectional, prospective method, using DRP - Registration Form V7.0 (PCNE) against 50 patients. The data were analyzed statistically using Chi-square test, paired t-test sample, and independent t-test, SPSS version 17.Results: The target hemoglobin not reaching 30 patients (60%), the level of hemoglobin target exceeded target 1 of the patients (2%). Based on the results of the test t, the value of p=0.038<0.05, then there is a difference in the level of hemoglobin after providing significant erythropoietin therapy between doses and less excess. Test the level of hemoglobin of erythropoietin therapy before and after using a test sample. Paired t-test based on the results, obtained significant value is 0.05, then 0.015< increased hemoglobin level after statistics are given significant therapy of erythropoietin.Conclusion: The results of this study indicate that there is an effect of DRPs related to excessive dosage; less dose to target hemoglobin level with significant value, so DRPs-associated dose affect the target hemoglobin level. 

scholarly journals Pengaruh Pemberian Informasi Obat Dengan Media Video Terhadap Kepatuhan Minum Obat Pasien Hipertensi Di Ungaran

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Dian Oktianti ◽  
Nova Hasani Furdiyanti ◽  
Sikni Retno Karminingtyas
Keyword(s):  
Health Center ◽  
Medication Compliance ◽  
Health Centre ◽  
Arterial Occlusion ◽  
Pill Count ◽  
T Test ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Improve Compliance ◽  
Paired T Test

Hipertensi merupakan salah satu penyakit kronis yang menjadi satu prioritas masalah  kesehatan  di  Indonesia  maupun  di  dunia. penyakit hipertensi dapat menyebabkan komplikasi seperti dapat menyebabkan oklusi arteri, cedera iskemik dan stroke sebagai komplikasi  jangka  panjang. Maka diperlukannya pemahaman oleh pasien tentang instruksi pengobatan dan peningkatan kepatuhan pasien melalui pemberian informasi obat dengan media video. Penelitian dilakukan secara prospektif dengan pretest-posttest design dan menggunakan rancangan cross sectional. Pengambilan sampel dilakukan secara purposive sampling dan didapatkan sampel sebanyak 40 orang. Data dianalisis menggunakan uji t-berpasangan. Hasil penelitian di Puskesmas Lerep menunjukkan kepatuhan sebelum intervensi kategori sedang 60%, kategori rendah 35% dan kategori tinggi 5%. Kepatuhan sesudah intervensi kategori sedang 20%, kategori rendah 0% dan kategori tinggi 80%. Nilai signifikansi uji t berpasangan yaitu 0,000 (<0,05). Hasil penelitian di Klinik Gracia kepatuhan pasien sebelum intervensi adalah rendah (20%), sedang (55%), dan tinggi (25%), setelah intervensi terjadi peningkatan kepatuhan yaitu rendah (5%), sedang (5%) dan tinggi (90%). Nilai signifikasi uji t-berpasangan dalam penelitian ini yaitu 0,000 < 0,05. Tingkat kepatuhan untuk uji pill count terdiri atas dua kategori yaitu patuh (kepatuhan≥80%) dan tidak patuh (kepatuhan<80%). Seluruh responden, baik pada Puskesmas Lerep maupun Klinik Gracia menunjukkan skor kepatuhan ≥80%, termasuk kategori patuh. Hasil penelitian menunjukan bahwa penyuluhan dengan media video dapat meningkatkan kepatuhan minum obat hipertensi di puskesmas Lerep dan Klinik Gracia.Kata Kunci : Hipertensi, Media Video, Kepatuhan Minum Obat, MMASHypertension is a chronic disease which is a priority health problem in Indonesia and in the world. Hypertension can cause complications such as can cause arterial occlusion, ischemic injury and stroke as long-term complications. Then there is a need to increase patient compliance by using video to provide drug information in order to increase patient’s understanding. The study was conducted prospectively with pretest-posttest design using cross sectional design. Forty sample was chosen by purposive sampling method. Data were analyzed using paired t-test. The results at Lerep Health Centre showed that the patient’s compliance before the intervention was categorized as moderate (60%), the low (35%) and high (5%). After the intervention, the moderate group was down to 20%, low was down to 0%, and the high group was increased to 80%. The significance value of paired t-test is 0,000 (<0.05). Research results at Gracia Clinic showed that patient’s compliance before intervention was low (20%), moderate (55%), and high (25%), and after intervention there was an increase in patient’s compliance that was low (5%), moderate (5%) and high (90 %). The significance value of paired t-test in this study is 0,000 <0.05. The level of adherence to the pill count test consists of two categories: adherence (80% adherence) and non-adherence (adherence <80%). All respondents, both at the Lerep Health Center and the Gracia Clinic showed a compliance score of ≥80%, including the compliance category. Counseling using video could improve compliance with taking hypertension medication at the Lerep health center and Gracia Clinic.Keywords: Hypertension, Video, Medication Compliance, MMAS

scholarly journals NATRIUM DALAM DARAH TENAGA KERJA SEBELUM DAN SESUDAH TERPAPAR PANAS (STUDI KASUS DI BAGIAN BUFFING PROCESS PT YAMAHA MUSICAL PRODUCTS INDONESIA PASURUAN TAHUN 2015)

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Vebrin Arsintha Tungga Dewi ◽  
Demes Nurmayanti ◽  
Ngadino .
Keyword(s):  
Total Population ◽  
Heat Stroke ◽  
T Test ◽  
P Value ◽  
Cross Sectional ◽  
Engineering Controls ◽  
Local Exhaust Ventilation ◽  
Exhaust Ventilation ◽  
Before And After ◽  
Paired T Test

Excessive exposure to heat resulting heat cramps, heat exhaustion and heat stroke. Workers who have not been acclimatized to hot temperatures are usually sweat more than usual. In this condition, human will lose body fluids and electrolytes. The purpose of this study analyzes the differences of sodium level in the blood of workers before and after exposure to heat.This is an observational analytic research with cross sectional approach. Data was obtained from the measurement result with total population of 15 workers and sample of 14 workers. The data was analyzed analytically by using Paired Sample T Test..The results shows that all workers aged less than 40 years with working period of less than five years and most of whom indicated normal nutritional status. The company has conducted engineering controls, administrative and PPE. P value was ≤ 0.01 and result of paired t test revealed highly significant.The Conclusion underlines difference in the level of sodium in workers’ blood before and after exposure to heat for 2.5 hours.Installation of local exhaust ventilation as well as the training of labor on heat stress and prevention is suggested.

scholarly journals Korelasi IgE terhadap rasio neutrofil/eosinofil jaringan dan darah penderita rinosinusitis kronik Aspergillus fumigatus

2018 ◽  
Vol 48 (1) ◽  
pp. 46
Author(s):  
Fifin Pradina Duhitatrissari ◽  
Endang Retnoningsih ◽  
Iriana Maharani
Keyword(s):  
Aspergillus Fumigatus ◽  
Pearson Correlation ◽  
Cross Sectional Study ◽  
T Test ◽  
Blood Levels ◽  
Cross Sectional ◽  
Pearson Correlation Test ◽  
The Mean ◽  
Polymerase Chain ◽  
Paired T Test

Latar Belakang: Prevalensi rinosinusitis kronik (RSK) jamur saat ini cenderung meningkat. Jamurberperan sebagai mikroorganisme dan merupakan salah satu penyebab RSK. Pemeriksaan immunoglobulinE (IgE) Aspergillus fumigatus (Af) digunakan untuk menegakkan diagnosis rinosinusitis jamur tanpa harusmelalui tindakan invasif. Perubahan rasio neutrofil/eosinofil (RNE) digunakan untuk memahami responinflamasinya. Tujuan: Mengetahui korelasi antara kadar IgE Af terhadap perubahan RNE mukosa dandarah pada penderita RSK jamur. Metode: Penelitian cross sectional, melibatkan 13 subjek penelitiandengan pengambilan darah dan mukosa sinus maksila untuk diidentifikasi Af dengan Polymerase ChainReaction (PCR), dilanjutkan ELISA untuk mengukur kadar IgE Af serta flowcytometry untuk mengukurkadar neutrofil dan eosinofil mukosa sinus maksila dan darah. Hasil: Rerata IgE Af mukosa 1,112±0,883kU/mL, darah 1,041±0,876 kU/mL (N<0,35 kU/L). Dengan uji T berpasangan didapatkan kesesuaian antarakadar IgE Af darah dan mukosa (p=0,852). Rerata eosinofil mukosa 3,9±1,92% (N:0,3-0,7%) dan darah4,88±2,02% (N:3-9%). Rerata neutrofil mukosa 4,28±2,04 (N:1,1-1,7%) dan darah 49,41±13,98% (N:55,8-59,6%). Rerata RNE mukosa 1,77±2,28 (N:2,8). Rerata RNE darah 12,12 ± 6,25 (N:9,6). Didapatkan93,3% mukosa subjek penelitian mengalami inflamasi eosinofilik, 53,3% mengalami inflamasi eosinofilikpada darah. Dengan uji T berpasangan terdapat ketidaksesuaian RNE mukosa dengan darah (p:0,000).Tes korelasi Pearson antara IgE Af dengan RNE mukosa, tidak terdapat korelasi bermakna (p:0,523) danantara IgE Af dengan RNE darah, tidak terdapat korelasi bermakna (p:0,607). Kesimpulan: Terdapatkesesuaian antara kadar IgE Af mukosa dan darah, tetapi tidak terdapat kesesuaian antara RNE mukosadan darah. Tidak terdapat korelasi antara peningkatan kadar IgE Af dengan RNE pada mukosa dan darah.  ABSTRACTBackground: The prevalence of chronic fungal rhinosinusitis (CFR) nowadays tends to increase.Fungi act as microorganisms and is one of the causes of chronic rhinosinusitis. The examination ofimmunoglobulin E (IgE) Aspergillus fumigatus (Af) is applied to establish the diagnosis of CFR withouthaving to do invasive actions. Neutrophil/eosinophil ratio (NER) changes are used to understand theinflammatory response. Purpose: To determine the correlation between IgE Af levels on changes ofmucosal and blood NER in CFR patients. Method: A cross-sectional study, involving 13 subjects bytaking sample of the blood and maxillary sinus mucosa to identify Af with Polymerase Chain Reaction(PCR), followed by ELISA to measure the levels of IgE Af, and flowcytometry to measure the levels ofneutrophils and eosinophils of the blood and mucosa of maxillary sinuses. Results: The mean IgE ofmucosa: 1.112±0.883kU/mL, and of blood: 1.041± 0.876kU/mL (N<0.35kU/L). With paired T-test,there was a match between blood and mucosal IgE level (p=0.852). The mean eosinophil of mucosa:3.9±1.92%,(N:0.3-0.7%) and of blood 4.88±2.02% (N:3-9%). The mean neutrophil of mucosa:4.28±2.04%(N:1.1-1.7%) and of blood 49.41± 13.98%(N:55.8-59.6%). The mean NER of mucosa:1.77±2.28(N:2.8), and of blood: 12.12±6.25(N:9.6). It was revealed that 93.3% of mucosal subjects hadeosinophilic inflammation, 53.3% had eosinophilic inflammation in blood. With paired T-test there wasa mucosal NER mismatch with blood (p:0.000). The Pearson correlation-test between IgE Af and NERmucosa had no significant correlation (p:0.523), and between IgE Af with NER of blood there was no significant correlation (p:0.607). Conclusion: There was a correspondence between IgE Af of mucosaand blood levels, but there was no match between the mucosal and blood NERs. There was no correlationbetween elevated levels of IgE Af and NER in the mucosa and blood.

Spirometric Assessment of Lung Function in Garment Workers in Bangladesh: A Cross Sectional Study

2020 ◽  
Author(s):  
Shamim Ahmed ◽  
◽  
Anita Rubaiya Husain ◽  
Shah Ashiqur Rahman Ashiq Choudhury ◽  
Mohammed Atiqur Rahman
Keyword(s):  
Pulmonary Function ◽  
T Test ◽  
Dust Exposure ◽  
Control Group ◽  
Cotton Dust ◽  
Cross Sectional ◽  
Respiratory Illnesses ◽  
Garment Workers ◽  
Female Workers ◽  
Paired T Test

Background: Exports of textiles and garments are the principal source of foreign exchange earnings in Bangladesh. Exports of textiles, clothing, and ready-made garments (RMG) account for 85% of Bangladesh’s total merchandise exports and provide employment to around 5 million workers. Workers of garment factories are susceptible to various respiratory morbid conditions, by virtue of workplace and working conditions and are at risk of suffering from various chronic respiratory illnesses. Early studies in textile workers throughout the world have focused on the relationship between hemp or cotton dust exposure and the development of a syndrome termed Byssinosis. Even though quite a few studies have been conducted in among garment workers in Bangladesh enough emphasis has not been given on the epidemiological aspects of chronic respiratory illnesses affecting pulmonary functions among the workers in these mills. Objective: The purpose of the study is to observe pulmonary function among garment workers in Bangladesh and compare it with unexposed population. Methods: This cross sectional observational study was conducted at cotton mill in Gazipur, Dhaka,Bangladesh. A control group was taken from BSMMU for the purpose of comparison. A modified questionnaire was used to inquire about socio demographic characteristics, socioeconomic history, complete occupational history, potential confounding factors, physical parameters and spirometry was done among workers. Results: There was significant association of pulmonary function FEV1, FVC, PEF with cotton dust exposure and a significant reduction of both FEV1 predicted 2.92±0.38 and observed 2.47±0.67 p<0.001 (paired t test) and PEF predicted 7.3%±1.10, observed 5.34±1.67, p<.001 (paired t test) was found among garment workers in comparison to non-exposed population group. Also female workers are more affected than male workers. No significant association of pulmonary function was found with the duration of exposure and distribution. Conclusion: We conclude that there is a significant association of pulmonary function in both long term and short term cotton exposed workers in comparison to non-exposed control group. There is a significant association of pulmonary function parameters (FEV1 and PEF) among female workers. It is justified to tell that cotton dust exposure has an effect on pulmonary function impairment. Keywords: Cotton dust, Garment workers, Pulmonary Function

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