Evaluation of the Antioxidant Activity of Some Plants Used in the Management of Erectile Dysfunction by the BWA Community in Mali

The erection has always symbolized strength and virile health. Erectile dysfunction is undoubtedly a concern as old as humanity. Tamarindus indica L., Guiera senegalensis J.F.Gmel and Ximenia americana L. are commonly used in the traditional treatment of erectile dysfunction by the Bwa community in Mali. The aim of this study was to measure the total polyphenols and flavonoids and then to evaluate the antiradical activity of the extracts (aqueous and hydroalcoholic macerated and decocted) of the organs of these species. The study found that for all species, the hydro-alcoholic macerated extract showed the best results. The polyphenol contents have been 36.85±0.21 mgGAE/g; 32.60±0.25 mgGAE/g and 29.79±0.51 mgGAE/g for Ximenia americana, Tamarindus indica and Guiera senegalensis respectively. The flavonoid contents have been 22.03±0.15 mgQE/g; 17.53±0.02 mgQE/g and 8.03±0.03 mgQE/g for Ximenia americana, Tamarindus indica and Guiera senegalensis respectively. The antiradical activity expressed in IC50 is 37.54±0.75 µg/mL; 52.75±0.71 µg/mL and 54.66±1.14 µg/mL for Ximenia americana, Tamarindus indica and Guiera senegalensis respectively. This study revealed that those plants are rich in total polyphenols and show a good antiradical activity. This wealth would justify their traditional use. The biological tests would be necessary to confirm their use in the treatment of erectile dysfunction. Keywords: Erectile dysfunction, polyphenols, antioxidant activity, Bwatun-Mali.

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The Dynamics of Total Polyphenols, Flavonoids and Antioxidant Activity of Beepollen Collected from Moldavia Area, Romania

Cercetari Agronomice in Moldova ◽

10.2478/v10298-012-0008-7 ◽

2012 ◽

Vol 45 (1) ◽

pp. 81-92 ◽

Cited By ~ 2

Author(s):

A. Prelipcean

Keyword(s):

Antioxidant Activity ◽

Antiradical Activity ◽

Storage Conditions ◽

Natural Light ◽

Total Flavonoids ◽

Solvent Concentration ◽

Total Polyphenols ◽

Fresh Pollen

The Dynamics of Total Polyphenols, Flavonoids and Antioxidant Activity of Beepollen Collected from Moldavia Area, RomaniaThe analysis sought to study the determination in timp and different conditions (temperature and light) of total polyphenols, flavones, total flavonoids and antioxidant activity from beepollen obtained with pollen colectors from Moldavia, Romania. Two methods vave been used, consisting in different concentrations of the methanolic solvent used. Analyses were performed on fresh pollen, stored for one and two weeks; at 4°C and 22°C; presence or absence of natural light. For every determination, five repetitions were made. There were fluctuations in the amounts of compounds, depending on the storage conditions and on the solvent used. The total polyphenols quantity ranged from 24.73 mg GAE/g to 28.8 mg GAE/g, when the methanolic solvent concentration was 96 % and from 21.67 mg GAE/g to 26.50 mg GAE/g, when the methanolic solvent concentration was 70 %. The flavones detected ranged from 7.23 mg QE/g to 8.93 mg QE/g (methanolic solvent 96%), and from 5.45 mg QE/g to 6.35 mg QE/g (methanolic solvent 70%). Total flavonoids have recorded values between 12.6 mg QE/g and 20.44 mg QE/g for the m.s. of 96%, and between 14.6 mg QE/g and 17.47 mg QE/g for the m.s. of 70%. The detected antiradical activity ranged from 22.68% to 29.78% inhibition (m.s. 96%), respectively from 21.31% to 25.55 % inhibition (m.s. 70%).

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Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520619666190416101622 ◽

2019 ◽

Vol 19 (13) ◽

pp. 1651-1657

Author(s):

Zouhaier Bouallagui ◽

Asma Mahmoudi ◽

Amina Maalej ◽

Fatma Hadrich ◽

Hiroko Isoda ◽

...

Keyword(s):

Antioxidant Activity ◽

Hepg2 Cells ◽

Cytotoxic Activities ◽

Phenolic Composition ◽

Olive Leaves ◽

Total Polyphenols ◽

Cytotoxic Effects ◽

Antioxidant Profile ◽

Phytochemical Profile ◽

Mcf 7

Aim: This study was designed to investigate the phytochemical profile and the cytotoxic activities of the eco-friendly extracts of olive leaves from Chemlali cultivar. Materials and Methods: The Phenolic composition of olive leaves extracts, the antioxidant activity and the cytotoxic effects against MCF-7 and HepG2 cells were determined. Results: Olive leaves extracts showed relevant total polyphenols contents. Oleuropein was the major detected phenolic compound reaching a concentration of 16.9 mg/ml. The antioxidant potential of the studied extracts varied from 23.7 to 46.5mM Trolox equivalents as revealed by DPPH and ABTS assays. Cytotoxicity experiments showed similar trends for both HepG2 and MCF-7 cells with the infusion extract being the most active. Conclusion: This study denotes that olive leaves may have great potential as endless bioresource of valuable bioactive compounds which may have a wide application.

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Investigation of Nutritional Contents, Antioxidant and Immunostimulatory Activities of Aqueous Extract from Laguncularia racemosa Leaves

The Natural Products Journal ◽

10.2174/2210315510666200108105217 ◽

2020 ◽

Vol 10 ◽

Author(s):

Dayane Kelly Dias do Nascimento Santos ◽

Cristiane Moutinho Lagos de Melo ◽

Elivânia Maria da Silva ◽

Vanessa Silva de Almeida ◽

Iranildo José da Cruz Filho ◽

...

Keyword(s):

Antioxidant Activity ◽

Aqueous Extract ◽

Antioxidant Activities ◽

Folk Medicine ◽

Proliferation Index ◽

Laguncularia Racemosa ◽

High Concentration ◽

Popular Medicine ◽

Biological Tests ◽

Phytochemical Profile

Background: One of the four most incident species in mangrove is the Laguncularia racemosa, plant widely used in popular medicine against inflammation and fever. Objective: Here, L. racemosa was investigated in relation to their phytochemical profile, antioxidant activity, citotoxicity, antimicrobial and immunostimulatory effect. Method: Aqueous extract was obtained from leaves of plant, its phytochemical profile was investigated through UPLC method, the antioxidant assays performed were TAA, DPPH, ABTS, nitrite and lipid peroxidation assay. Antimicrobial assays were made using standard strains. For all biological tests were used mice splenocytes and from these cell cultures were measured cytotoxicity, proliferation index and cytokines production. Results: Laguncularia racemosa leaves showed the presence of ions, proteins, carbohydrates, vitamins and high concentration of phenolic compounds. Antioxidant activities were promoted by aqueous extract, especially in DPPH and NO assays. Extract in 6 µg/mL did not induce significant cell death, stimulated the cell proliferation and the IL-4 production. Moreover, decreases of proinflammatory cytokines IFN-γ, TNF-α and IL-6 were found. Conclusion: The presence of essential nutrients, significant antioxidant activity and immune stimulation confirm the use of this plant in folk medicine against inflammation.

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Comparative Assessment of the Basic Chemical Composition and Antioxidant Activity of Stevia rebaudiana Bertoni Dried Leaves, Grown in Poland, Paraguay and Brazil—Preliminary Results

Applied Sciences ◽

10.3390/app11083634 ◽

2021 ◽

Vol 11 (8) ◽

pp. 3634

Author(s):

Teresa Leszczyńska ◽

Barbara Piekło ◽

Aneta Kopeć ◽

Benno F. Zimmermann

Keyword(s):

Antioxidant Activity ◽

Chemical Composition ◽

Vitamin C ◽

Dietary Fiber ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Stevia Rebaudiana ◽

Steviol Glycosides ◽

Total Polyphenols ◽

Stevia Rebaudiana Bertoni

This study compares the content of basic nutrients (proteins, fats, digestible carbohydrates, dietary fiber and ash), steviol glycosides, selected antioxidants (vitamin C, total polyphenols) and antioxidant activity in dried leaves of Stevia rebaudiana Bertoni cultivated in Poland, Paraguay and Brazil and available in the direct sale. The basic chemical composition was determined by standard AOAC (Association of Official Analytical Chemists) methods. Content of steviol glycosides was determined by the UHPLC-UV chromatographic method. Total polyphenols content was expressed as gallic acid equivalent (GAE) and catechins equivalent (CE). Antioxidant activity was measured as ABTS●+ free radical scavenging activity. Dried leaves of S. rebaudiana grown in Poland had significantly higher contents of dietary fiber, and lower protein and ash content, compared to those derived from Paraguay and Brazil. The former had, however, considerably higher contents of total steviol glycosides, stevioside and rebaudioside D, compared to the remaining two plants. In the Paraguay-derived dried leaves, the content of rebaudioside A, C, E and rubusoside was found to be significantly lower. Dried leaves of S. rebaudiana Bertoni, cultivated in Poland, contained substantially more vitamin C and a similar content of total polyphenols, compared to those from Brazil and Paraguay. The examined material from Brazil and Paraguay plantations showed similar antioxidant activity, while that obtained from Polish cultivation was characterized by a significantly lower value of this parameter.

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Effect of Ultrasound-Assisted Extraction Parameters on Total Polyphenols and Its Antioxidant Activity from Mango Residues (Mangifera indica L. var. Manililla)

Separations ◽

10.3390/separations8070094 ◽

2021 ◽

Vol 8 (7) ◽

pp. 94

Author(s):

Anahí J. Borrás-Enríquez ◽

Elizabeth Reyes-Ventura ◽

Socorro J. Villanueva-Rodríguez ◽

Lorena Moreno-Vilet

Keyword(s):

Antioxidant Activity ◽

Mangifera Indica ◽

Central Point ◽

Added Value ◽

Sonication Time ◽

Ultrasound Assisted Extraction ◽

Extraction Technology ◽

Total Polyphenols ◽

Assisted Extraction ◽

Ultrasound Assisted

Manililla is a mango variety whose residues contain bioactive compounds such as polyphenols and flavonoids, with high added value. The use of environmentally friendly extraction technology would be of great relevance; hence, this study aimed to evaluate the effect of solvent relation, sonication time and amplitude on the ultrasound-assisted extraction of total polyphenols in Manililla mango residues (peel, endocarp and kernel) and antioxidant activity. An experimental design 23 with a central point was used to evaluate the curvature behavior of the process variables. Conventional maceration was used as a control. The better conditions were obtained at the central point using 50% ethanol in water, 60% amplitude and 20 min of sonication time. We obtained values of up to 1814 mg GAE/100 g, 469 mg GAE/100 g and 672 mg GAE/100 g of total polyphenols and 1228 mg QE/100 g, 653 mg QE/100 g and 880 mg QE/100 g of total flavonoids for peel, endocarp and kernel, respectively. Mangiferin was quantified in ultrasound-assisted extraction at 150 mg/g in peel and 0.025 mg/g in the kernel, but it was not detectable in maceration. An antioxidant capacity of 87%, 14% and 83% inhibition for peel, endocarp and kernel, respectively, were obtained. Peel and kernel were the residues with higher potential as extraction material, while endocarp was not.

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Phytochemical and Antioxidant Dynamics of the Soursop Fruit (Annona muricata L.) in response to Colletotrichum spp.

Journal of Food Quality ◽

10.1155/2020/3180634 ◽

2020 ◽

Vol 2020 ◽

pp. 1-12

Author(s):

Alejandro Rubio-Melgarejo ◽

Rosendo Balois-Morales ◽

Yolotzin Apatzingan Palomino-Hermosillo ◽

Graciela Guadalupe López-Guzmán ◽

José Carmen Ramírez-Ramírez ◽

...

Keyword(s):

Antioxidant Activity ◽

Antiradical Activity ◽

Late Response ◽

Total Phenols ◽

Annona Muricata ◽

Coumaric Acid ◽

Colletotrichum Siamense ◽

Soluble Phenols ◽

Colletotrichum Spp ◽

Higher Sensitivity

This work evaluates the effect of the pathogens Colletotrichum siamense and C. gloeosporioides on the response of soursop fruits. The bioactive compounds (total phenols, flavonoids, anthraquinones, coumarins, steroids, terpenoids, alkaloids, and saponins) were evaluated qualitatively in soursop pulp. Positive phytochemicals and antioxidant activity (DPPH•, ABTS•+, and FRAP) were quantified at day zero, one, three, and five. Fruits treated with C. gloeosporioides showed higher disease severity (P<0.05). Early fruit response (day one) was observed with both pathogens, increased the concentration of saponins and repressed the production of quercetin 3-O-glucoside (P<0.05). Likewise, C. siamense decreased total soluble phenols and flavonoids and increased antiradical activity DPPH•. Besides, C. gloeosporioides decreased the levels of kaempferol 3-O-rutinoside and ferulic acid (P<0.05). Regarding the late response (day three), both pathogens decreased the concentration of saponins and increased flavonoids and phytosterols (P<0.05). Nevertheless, C. siamense increased the levels of total soluble phenols, p-coumaric acid, kaempferol, and antiradical activity FRAP (P<0.05). Also, C. gloeosporioides repressed the production of quercetin 3-O-glucoside at day five (P<0.05). Soursop fruits had a response to the attack of Colletotrichum during ripening at physicochemical and oxidative levels, which is associated with the production of compounds related to the development inhibition of pathogens. Even so, soursop fruits showed higher susceptibility to C. gloeosporioides and higher sensitivity to the attack of C. siamense.

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Anthocyanins, total polyphenols and antioxidant activity in amaranth and quinoa seeds and sprouts during their growth

Food Chemistry ◽

10.1016/j.foodchem.2009.01.037 ◽

2009 ◽

Vol 115 (3) ◽

pp. 994-998 ◽

Cited By ~ 184

Author(s):

Paweł Paśko ◽

Henryk Bartoń ◽

Paweł Zagrodzki ◽

Shela Gorinstein ◽

Maria Fołta ◽

...

Keyword(s):

Antioxidant Activity ◽

Total Polyphenols

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Phytochemical Screening And Evaluation Of The Antioxidant Activity Of Essential Oil Of Pistacia Atlantica Harvested From The Ouled Brahim Region, Saida; Algeria

South Asian Journal of Experimental Biology ◽

10.38150/sajeb.8(6).p202-206 ◽

2019 ◽

Vol 8 (6) ◽

pp. 202-206

Author(s):

Attou Fatima ◽

Terras Mohamed ◽

Ammam Abdelkader ◽

Tabet Aouel Faiza

Keyword(s):

Antioxidant Activity ◽

Essential Oil ◽

Essential Oils ◽

Plant Material ◽

Local Population ◽

Traditional Healers ◽

Phytochemical Screening ◽

Traditional Use ◽

Phytochemical Study ◽

Antioxidant Power

The knowledge of traditional healers o en represents a basis for the pharmacological and phytochemical inves ga on of naturals medicaments. This work aims for the phytochemical study and evaluation of the antioxidant activity of essential oils of medicinal plant Pistacia atlantica.Through the results obtained, it appears that the leaves are rich in substances with a high antioxidant power. For essential oils, it is 0.24 % for 100 g of plant material. And the phytochemical screening of the plant showed the presence of tannins, resins, coumarins, terpenoids and flavonoids, and absence of saponins. The strong antioxidant activity of extracts obtained only confirms the traditional use of this plant by the local population.

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Aktywność biologiczna ekstraktów z propolisu

Postępy Fitoterapii ◽

10.25121/pf.2021.22.1.8 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Magdalena Woźniak ◽

Anna Kwiatkowska ◽

Elżbieta Hołderna-Kędzia ◽

Katarzyna Sosnowska ◽

Lucyna Mrówczyńska ◽

...

Keyword(s):

Antioxidant Activity ◽

Biological Activity ◽

Phenolic Compounds ◽

Propylene Glycol ◽

Ethyl Alcohol ◽

Antiradical Activity ◽

Colorimetric Method ◽

Biological Properties ◽

Bioactive Substances ◽

Dpph Test

Introduction. Propolis, also known as bee glue, is a resinous material collected by honeybees with numerous biological properties, including antibacterial, antifungal, antioxidant and anticancer effects. Due to its health-promoting properties, propolis is a component of many products, including dietary supplements, cosmetics and healthy food. Aim. The aim of the study was to determine the antibacterial, antifungal and antioxidant activity of propolis extracts, as well as to compare the biological activity of propolis extracts, depending on the solvent used – ethyl alcohol or propylene glycol. Material and methods. Two propolis extracts were used in the research – the first was prepared in ethyl alcohol, and the second in propylene glycol. The antimicrobial activity of the examined extracts was determined against S. aureus, E. coli and C. albicans. The antioxidant activity was determined on the basis of the evaluation of their antiradical activity in the DPPH· test and Fe2+ chelating activity. Moreover, the total content of phenolic compounds and flavonoids in the tested extracts was determined using the colorimetric method. Results. The tested propolis extracts, regardless of the solvent used (ethyl alcohol or propylene glycol), showed high antibacterial (against S. aureus), antifungal (against C. albicans) and antioxidant (antiradical activity in the DPPH· test and ferrous iron chelating potency in the ferrozine test) activity. Moreover, both tested extracts were characterized by a high and similar content of bioactive compounds – phenolic compounds and flavonoids. Conclusions. The results of the conducted tests showed that the solvent used did not affect determined biological activity and the content of bioactive substances in the tested propolis extracts.

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