scholarly journals STATUS ANGKA BEBAS JENTIK KOTA BANDA ACEH SEBAGAI DAERAH ENDEMIS DEMAM BERDARAH DENGUE TAHUN 2014

Author(s):  
Yulidar Yulidar

One of vector borne deseases which still remains a health problem in Indonesia is dengue fever (DBD). This desease is caused by dengue virus transmitted by Aedes aegypti mosquitoes. One of cities which is endemic for DBD in 2014 was Banda Aceh. The indicator for DBD endemic is based on entomology index. One of entomology index to be measured is the number of mosquito larvae-free. To know the status of mosquito larvae-free number in Banda Aceh, a suvey has been conducted in three subdistricts within Banda Aceh city, namely Banda Raya (Lamlagang village), Ulee Kareng (Ceurih village), and Baiturrahman (Peuniti village). A survey was conducted in 100 houses of every subdistrict. The total of 300 houses were investigated. From 300 houses investigated, there were 158 houses were positively had mosquito larvae. From 860 containers that were found and checked in those three subdistricts, it was found that there were 235 containers were positively contained mosquito larvae. The container which contained mosquito larvae dominantly was bathups inside the houses, there were 48,22% of larvae and 60,47% of pupas. The results showed that the number of mosquito larvae-free for Banda aceh was 47,33% which indicated that it was still below the number of national larvae-free that is > 95%. Therefore, Banda Aceh is still in a high risk of DBD transmission in the future.

Author(s):  
Nurul Qamila ◽  
Agel Vidian Krama

Dengue hemorrhagic fever (DHF) is a contagious disease caused by the dengue virus and is transmitted by the mosquito Aedes aegypti (Aa.aegypti). The population is still a public health problem that increases the number of sufferers and also widespread, with population and education. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the spatial pattern and the spread of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the descriptive method and spatial pattern of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. Keywords: DHF, Spatial Analysis


2015 ◽  
Vol 7 (2) ◽  
Author(s):  
Meiranty C. Pangerapan ◽  
Beivy J. Kolondam

Abstract: Dengue virus is a single-stranded RNA virus that belongs to Flaviviridae family. This virus causes dengue fever which is transmitted by Aedes aegypti dan Aedes albopictus. There are four serotypes of dengue virus; all of them can cause dengue fever. Understanding the genomics of dengue virus is important for research and diagnostics. The genome of dengue virus is 11 kilo-base long. It consists of 5’-untranslated region (5’-UTR), three structural genes (coding capsid protein, pre-membrane/membrane, and envelope), seven non-structural genes (coding NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5 proteins) and 3’-UTR. Non-structural genes are encoding proteins of viral RNA replication, interferon response, viral assembly and secretion, endoplasmic reticulum membrane invagination induction, immune-mediator induction, and RNA 5’-caping.Keywords: dengue virus, genome, structural genes, non-structural genes, untranslated region.Abstrak: Virus dengue merupakan virus RNA beruntai tunggal yang termasuk dalam famili Flaviviridae. Virus ini adalah penyebab penyakit demam berdarah dengue yang ditransmisikan melalui nyamuk Aedes aegypti dan Aedes albopictus. Ada empat serotipe virus dengue yang telah dikenal secara luas yang ada semuanya dapat menimbulkan penyakit demam berdarah. Pemahaman tentang genomik virus dengue sangat penting untuk pengembangan penelitian dan juga untuk keperluan diagnostik. Genom virus dengue memiliki panjang 11 kilo basa. Genomnya tersusun atas 5’-untranslated region (5’-UTR), tiga gen struktural (mengodekan protein kapsid, premembran/membran dan amplop), tujuh gen non-struktural (mengodekan protein NS1, NS2A, NS2B, NS3, NS4A, NS4B dan NS5) dan 3’-UTR. Gen-gen non-struktural mengodekan protein untuk replikasi RNA virus, respon interferon, perakitan, sekresi partikel virus, menginduksi invaginasi membran retikulum endoplasma, induksi imunomediator dan penambahan tudung pada ujung 5’ RNA.Kata kunci: virus dengue, genom, gen struktural, gen non-struktural, untranslated region


2018 ◽  
Author(s):  
Mabel L. Taracena ◽  
Vanessa Bottino-Rojas ◽  
Octavio A.C. Talyuli ◽  
Ana Beatriz Walter-Nuno ◽  
José Henrique M. Oliveira ◽  
...  

AbstractAedes aegypti is the vector of some of the most important vector-borne diseases like Dengue, Chikungunya, Zika and Yellow fever, affecting millions of people worldwide. The cellular processes that follow a blood meal in the mosquito midgut are directly associated with pathogen transmission. We studied the homeostatic response of the midgut against oxidative stress, as well as bacterial and dengue virus (DENV) infections, focusing on the proliferative ability of the intestinal stem cells (ISC). Inhibition of the peritrophic matrix (PM) formation led to an increase in ROS production by the epithelial cells in response to contact with the resident microbiota, suggesting that maintenance of low levels of ROS in the intestinal lumen is key to keep ISCs division in balance. We show that dengue virus infection induces midgut cell division in both DENV susceptible (Rockefeller) and refractory (Orlando) mosquito strains. However, the susceptible strain delays the activation of the regeneration process compared with the refractory strain. Impairment of the Delta/Notch signaling, by silencing the Notch ligand Delta using RNAi, significantly increased the susceptibility of the refractory strains to DENV infection of the midgut. We propose that this cell replenishment is essential to control viral infection in the mosquito. Our study demonstrates that the intestinal epithelium of the blood fed mosquito is able to respond and defend against different challenges, including virus infection. In addition, we provide unprecedented evidence that the activation of a cellular regenerative program in the midgut is important for the determination of the mosquito vectorial competence.


2019 ◽  
Vol 13 (1) ◽  
pp. 1-6
Author(s):  
MIRNA WATI DEWI ◽  
Susi Soviana ◽  
Umi Cahyaningsih ◽  
Ali Rahayu

Abstract Dengue fever is a vector-borne disease with Aedes aegypti as the main vector. Vector controls currently depended on insecticide. Considering the negative effect of insecticide, Sterile Insect Technique (SIT) was developed. This study was conducted to evaluate the effect of gamma-ray irradiation on the productivity of male Ae. aegypti. Male pupae age less than 15 hours were irradiated with 60 Gy and 70 Gy gamma-ray. When the pupae became adult, the sterile males mated with the same age females Aedes aegypti. Observation on fecundity, hatchability, and age was carried out until the second generation. Gamma-ray irradiation with the dose of 60 Gy and 70 Gy showed different effects on fecundity, egg hatchability, the emergence of the adult, and age of Aedes aegypti compared to control. Abstrak Demam berdarah merupakan penyakit tular vektor  yang sampai saat ini masih menjadi masalah kesehatan secara global. Vektor utama yang berperan pada penyebaran penyakit DBD yaitu nyamuk Aedes aegytpi. Pengendalian vektor saat ini sangat bergantung pada penggunaan insektisida. Dampak negatif penggunaan insektisida menyebabkan pengembangan pengendalian vektor yang lain diantaranya yaitu Teknik Serangga Mandul (TSM). Penelitian ini dilakukan untuk menganalisis produktivitas Ae. aegypti jantan iradiasi hingga generasi kedua. Pupa jantan umur <15 jam diradiasi sinargamma dosis 60 Gy dan 70 Gy. Setelah menjadi nyamuk jantan dewasa segeradikawinkan dengan nyamuk betina tidak iradiasi dengan umur yang sama. Pengamatan dilakukan terutama terhadap fekunditas, daya tetas, kemunculan nyamuk, dan umurnyamuk hingga generasi kedua. Iradiasi sinar gamma dosis 60 Gy dan 70 Gymenghasilkan dampak yang berbeda terhadap fekunditas, daya tetas telur, kemunculan nyamuk dan umur nyamuk bila dibandingkan dengan kontrol.


2014 ◽  
Vol 8 (8) ◽  
pp. 423
Author(s):  
Sunaryo Sunaryo ◽  
Nova Pramestuti

Demam Berdarah Dengue (DBD) perlu mendapat perhatian serius karena masih menjadi masalah kesehatan di Indonesia dan di beberapa daerah masih sering terjadi kejadian luar biasa. Di Jawa Tengah, kasus DBD cenderung meningkat setiap tahunnya terutama pada tahun 2012. Penelitian ini bertujuan menganalisis parameter entomologi dan menggambarkan jenis tempat penampungan air. Penelitian dilakukan di Kabupaten Grobogan, Purbalingga, Kendal dan Kota Semarang pada bulan Juni - Oktober 2013 desain potong lintang. Survei jentik dilakukan untuk melihat keberadaan tempat penampungan air pada 100 rumah. Masing-masing kabupaten dipilih tiga lokasi desa endemis DBD. Hasil survei digunakan untuk menghitung nilai parameter entomologi. Hasil penelitian menunjukkan bahwa meningkatnya kasus DBD di empat kabupaten/kota terkait dengan keberadaan vektor A. aegypti. Hal ini dibuktikan dengan masih tingginya persentase jumlah rumah yang ditemukan jentik A. aegypti (House Index > 10%) serta tingginya jumlah kontainer ditemukan jentik A. aegypti pada rumah yang dilakukan survei (Breteau Index). Nilai ovitrap index paling tinggi di Desa Kalikabong Kabupaten Purbalingga sebesar 40%. Proporsi controllable site lebih banyak daripada disposable site, berarti rumah tersebut berisiko tinggi sebagai tempat perkembangbiakan nyamuk.Dengue Haemorrhagic Fever (DHF) needs serious attention because it is still a health problem in Indonesia and in recent area DHF caused outbreak. In Central Java, incidence of DHF high every years, especially in 2012. This study aimed to analyze the parameters of entomology and describe types of containers. The study was conducted in Grobogan, Purbalingga, Kendal District and Semarang City in June _ October 2013 with cross-sectional design. Larvae survey had been done in 100 houses in three villages that endemic DHF at every district/city. The survey results are used to calculate parameter entomology. The results showed that existance of DHF cases in four district/city connected with the population of A. aegypti. This matter proved with high percentage of houses that found A. aegypti (House Index > 10%) and the high of container that containing A. aegypti in every houses (Breteau Index). The high of ovitrap index (OI) was 40% in Kalikabong village, Purbalingga district. The proportion of controllable sites more than disposable sites, meaning the house as the high risk of mosquito breeding sites. 


2017 ◽  
Vol 3 (6) ◽  
pp. 41
Author(s):  
Hamidah Hamidah ◽  
Hebert Adrianto

Dengue Fever is a significant health issue in Indonesia for it is always been found and unresolved since 1968. Dengue Fever is transmitted through mosquito (Aedes aegypti) bite. Resistance of mosquito larvae towards temephos as consequence of chemical larvicide consumption has been reported in several countries. One of safe and environmentally friendly efforts to control mosquito is by using herbal larvicide which produced from plants. This study examines methanol extract of Citrus mitis, Citrus aurantifolia, and Citrus maxima leaf toward mosquito larvae Ae. aegypti instar III for 24 hours. Data of larvae mortality is analyzed using probit analysis by SPSS software. The result shows that Citrus mitis has the highest toxicity with the lowest lethal concentrations (LC) that are LC50 = 1.547 ppm and LC90 = 3.328 ppm. It followed by Citrus aurantifolia and Citrus maxima respectively.Keywords: larvicide; Aedes aegypti; leaf extract; Citrus mitis; Citrus aurantifolia; Citrus maxima


2020 ◽  
Vol 1 (2) ◽  
pp. 110-121
Author(s):  
Thoeng Fenni C. Effendy ◽  
Hasanuddin Ishak ◽  
Agus Bintara Birawida

Makassar City is one of the areas most at risk of Dengue Fever (DHF). One form of dengue prevention is to break the chain of transmission of mosquitoes, which is to prevent the breeding of mosquito vectors through efforts to eradicate mosquito nests (PSN). Mapping the density of aedes aegypti mosquitoes based on the behavior of eradicating mosquito nests (PSN) in Paccerakkang Village, Tamalanrea Village, Makassar City. This type of research is an observational survey with cross sectional method with descriptive analytic approach and using a questionnaire as an interview guide. The sample in this study was the house of DHF sufferers and houses within a radius of 100 meters from patients who were in Paccerakkang Village as many as 98 houses and Tamalanrea Village 61 houses were determined using purposive sampling method. The results of this study found that 39.8% of respondents' houses in Paccerakkang were found to be larvae and in Tamalanrea at 62.3%. 3M's behavior in both village is also incomplete and low, namely 14.3% and 13.1% respectively, while the use of bubate abate is 48% and 34.4%. Based on the Density Figure (DF) determined by WHO, the two villages are included in areas with Angka Bebas Jentik (ABJ) which have a high risk of DHF transmission.


2020 ◽  
Vol 19 (2) ◽  
pp. 111-118
Author(s):  
Esy Maryanti ◽  
Ismawati Ismawati ◽  
Unique Prissilia ◽  
Ardini Yovy Puteri

Latar belakang: Demam berdarah dengue (DBD) merupakan penyakit yang masih menjadi masalah kesehatan di Indonesia yang disebabkan oleh virus dengue dan ditularkan melalui nyamuk Aedes aegypti. Kejadian DBD selalu ada setiap tahun di Pekanbaru dari tahun 2014-2016 terjadi peningkatan kasus, 2017-2018 kasus DBD mulai menurun tetapi diawal tahun 2019 kasus DBD kembali terjadi peningkatan dan sudah ada kematian sehingga memerlukan perhatian yang lebih serius untuk meningkatkan kewaspadaan terhadap penyakit tersebut. Tujuan penelitian ini adalah untuk menganalisis potensi transmisi DBD berdasarkan indeks entomologi dan maya indeks di tiga kelurahan Kecamatan Sukajadi yang merupakan daerah endemis DBD. Metode: Penelitian survei larva Aedes aegypti dengan pendekatan cross sectional yang dilakukan pada bulan Juli 2019 di tiga kelurahan yaitu Kelurahan Kampung Tengah, Kampung Melayu, Kedungsari Kecamatan Sukajadi. Identifikasi larva menggunakan metode single larva method. Hasil: Sebanyak 181 rumah yang disurvey, didapatkan 822 kontainer yang terdiri dari 683 controllable sites dan 139 disposable sites. Angka bebas jentik sebesar 89,5%, container index 3,4%, house index 10,5% dan Breteau index 21%. Status Maya indeks (MI) yang diukur berdasarkan breeding risk index dan hygiene risk index didapatkan sebanyak 55,80% rumah termasuk dalam status sedang dan 15,47% termasuk ke dalam status MI tinggi. Sebaran keberadaan larva Aedes aegypti berdasarkan letak geografis cukup merata di Kelurahan Kampung Melayu dan Kampung Tengah.Simpulan: Berdasarkan hasil indeks entomologi tersebut didapatkan density figure dalam kategori sedang yang artinya wilayah ini mempunyai potensi transmisi sedang untuk kejadian penyakit DBD. ABSTRACT  Title : Transmission Potential of Dengue hemorrhagic fever based on entomology index and maya index in three sub-districts, Sukajadi District, Pekanbaru CityBackground: Dengue hemorrhagic fever (DHF) is a disease still a health problem in Indonesia caused by the dengue virus that is transmitted through Aedes aegypti. The incidence of DHF is always there every year in Pekanbaru form 2014-2016 there was an increase in cases, from 2017-2018 dengue cases began to decline, but in early 2019 dengue cases increased again and there have been deaths so it requires more serious attention.. The objectives of this study was to analyze the potential transmission of DHF based on the entomology index and maya index in three sub-districts of Sukajadi district.Method: The research was a survey of larva Ae.aegypti in July 2019 from 181 houses in the three village of Sukajadi District. Larvae identification using the single larvae method.Result: A total of 181 houses surveyed obtained 822 containers consisting of 683 controllable sites and 139 disposable sites. The larvae free rates is 89.5%, container index 3.4%, house index 10,5% and Breteau index 21%. Maya index is measures based on breeding risk index and hygiene risk index shows that there are 55.8% of houses in the area are classified as moderate and 15.47% are included in high. The distribution of the existence of Ae.aegypti larvae based on the geographical location is quite evenly distributed in Kampung Melayu and Kampung Tengah.Conclusion: It is found that density figure is in the medium, which means that region has moderate transmission potential for the incidence of DHF


Author(s):  
Alfian Rahmawan ◽  
Farid Ma'ruf

DBD is an infectious disease by the Dengue virus, which is transmitted through the bite of Aedes aegypti mosquitoes. This disease's characteristics include sudden high fever accompanied by bleeding manifestations and the tendency to cause shock that can cause death. Until now, there is no cure for dengue fever or a vaccine. So the only way to prevent this disease is to break the chain of transmission. The main factor of dengue fever in Indonesia is the Aedes aegypti mosquito. Another way to avoid dengue fever is the correct 3M plus method, namely 1. Close, cover all places that can hold water, both inside and outside the house. 2. Drain, drain water reservoirs such as bathtubs, aquariums, and flower vases two times a week. The mosquito metamorphosis cycle, from egg to adult mosquito, lasts 8-10 days. 3. Bury. Bury all objects that can hold water, such as used cans or plastic containers. However, in the 3M movement, which has been renewed to 3M plus, this third M is no longer recommended because it can cause soil pollution


2012 ◽  
Vol 3 (1) ◽  
Author(s):  
Suharno Zen

Dengue fever is an infectious disease caused by a virus and is transmitted by the Aedes aegypti mosquito. Dengue fever has not yet found a cure and the only prevention is through mosquito vector  control. Health Department policy to prevent and eradicate dengue fever today is to make eradication by means of mechanical, physical, chemical or biological. Biological is one of alternative  control of mosquito vectors that are safe for humans and the environment but still effective in suppressing the mosquito vector. One attempt to do that is by using animals to fight other creatures, or better known as biological control. In the present research was performed using fish of Betta spp, Cyprinus carpio and Oreochormis niloticus as a natural predator of the Aedes aegypti mosquito. The design of this research is  Completely Randomized Design (CRD) with three treatments are 3 types of fish with 5 times repeated. Data were analyzed with analysis of the range and tested further with the Smallest Real Differences Test (LSD) on the real level 5%. The result of this research is the ability Betta spp eating is higher than the Oreochromis niloticus and Cyprinus carpio by the number of larvae that consumed between 34.6 to 36.9 mosquito larvae tail. The ability to eat at various types of fish against mosquito larvae, influenced by several factors: the agressive, espesialisasi fish to food, the active duration and the amount of time the fish is active in 24 hours.


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