scholarly journals Therapeutic strategies to fight COVID-19: which is the status artis?

2021 ◽  
Author(s):  
Cristina Scavone ◽  
Annamaria Mascolo ◽  
Concetta Rafaniello ◽  
Liberata Sportiello ◽  
Ugo Trama ◽  
...  
Keyword(s):  
Complex Disease ◽  
Antiviral Agents ◽  
Safety Data ◽  
Real Life ◽  
Marketing Approval ◽  
The Us ◽  
The Status ◽  
Life Context ◽  
Inflammatory Drugs

COVID-19 is a complex disease and many difficulties are faced today especially in the proper choice of pharmacological treatments. The role of antiviral agents for COVID-19 is still being investigated. The evidence for immunomodulatory and anti-inflammatory drugs is quite conflicting, while the use of corticosteroids is supported by robust evidence. The use of heparins in hospitalized critically ill patients is preferred over other anticoagulants. Lastly, conflicting data were found regarding to the use of convalescent plasma and vitamin D. According to data shared by the WHO, many vaccines are under phase 3 clinical trials and some of them already received the marketing approval in EU countries and in the US. In conclusion, drugs repurposing has represented the main approach recently used in the treatment of patients with COVID-19. At this moment, the analysis of efficacy and safety data of drugs and vaccines used in real life context is strongly needed.

Scripturalizing and the Second Amendment

2018 ◽  
Author(s):  
Rosamond C. Rodman
Keyword(s):  
White Women ◽  
White Children ◽  
The Bible ◽  
Second Amendment ◽  
The Us ◽  
The Status ◽  
Us Constitution ◽  
Half Decade

Expanding beyond the text of the Bible, this chapter explores instead a piece of political scripture, namely the Second Amendment of the US Constitution. Over the last half-decade, the Second Amendment has come to enjoy the status of a kind of scripture-within-scripture. Vaulted to a much more prominent status than it had held in the first 150 years or so of its existence, and having undergone a remarkable shift in what most Americans think it means, the Second Amendment provides an opportunity to examine the linguistic, racial, and gendered modes by which these changes were effected, paying particular attention to the ways in which white children and white women were conscripted into the role of the masculine, frontier-defending US citizen.

scholarly journals Make comedy matter: Ernst Cassirer on the politics and morality of humor

2018 ◽  
Vol 6 (1) ◽  
pp. 162
Author(s):  
Jennifer Marra
Keyword(s):  
Intrinsic Value ◽  
Third Reich ◽  
Ernst Cassirer ◽  
Political Forces ◽  
The Us ◽  
Political Myth ◽  
The Status ◽  
Public Consciousness ◽  
The Third Reich

Many of Ernst Cassirer’s later works are concerned with the dangers of political myth. His analysis speaks at length about the role of philosophy during the rise of the Third Reich, and Cassirer argues that philosophers failed to combat the dominant ideology. Today, philosophers struggle to explain their relevance to greater public and governmental powers that see no intrinsic value. Given the current political situation in the US, we find ourselves at a crossroads as philosophers. We can either retreat and remain within the comforts of academia, or we can take up arms against dangerous and divisive political forces. If we take Cassirer’s prescriptions seriously, we must choose the latter. Fortunately, philosophy has not disappeared from public consciousness completely. An emerging theme in contemporary cultural studies is the exploration of connections between humour and philosophy. I argue we ought to take advantage of the status of the comedian as public philosopher, and for philosophers to take seriously the political power of comedians. To do this responsibly, I analyse a portion of Cassirer’s work that has been widely ignored in scholarship – his understanding of the politics and morality of humour. By analysing these passages in relation to Cassirer’s later works, we are given the tools to understand the power of humour in political discourse, as well as the responsibility of that power. I argue that “joking responsibly”, for Cassirer, means to reveal the motives and values which underlie sophistry, particularly the sort which lends itself to political manipulation.

scholarly journals The evolution of female image in the works of Vajiravudh

Litera ◽  
2021 ◽  
pp. 37-44
Author(s):  
Kseniya Borisovna Volkova
Keyword(s):  
Real Life ◽  
Traditional Values ◽  
Ethical Perspective ◽  
Female Images ◽  
Thai Language ◽  
Thai Woman ◽  
Female Image ◽  
The Status ◽  
Status Of Women

The object of this research is the evolution of female image in the works of King Vajiravudh of Siam, who is considered the father of modern Thai literature. The subject of this research is the portraits of heroines in the original Thai-language works of the monarch, both dramatic and epic, which allow us tracing the artistic transformations of female images. The historical and biographical methods reveal the status of women in the new Thai society of the early XX century and how it affect the author’s views. The problematic of the “feminine” was associated with the author’s pursuit of ideal of Thai woman from ethical perspective. This is the first research on the topic within Thai or foreign historiography. The female images, the role of women in society and fate of the nation is the pervasive theme in all works by King Vajiravudh. The author disrupts the traditional canon and depicts a new woman, who claims her rights to the freedom of choice despite the patriarchal principles. At the same time, the entire gallery of female images is an attempt to find compromise between the progress and traditional values, to create the ideal of Thai woman, which could find realization in real life.

scholarly journals Strategic stability and the possibilities of China's involvement in the strategic arms control negotiations

2020 ◽  
Vol 72 (4) ◽  
pp. 678-708
Author(s):  
Marina Kostic
Keyword(s):  
Nuclear Weapons ◽  
Comparative Method ◽  
Arms Control ◽  
Main Hypothesis ◽  
Defense Strategies ◽  
Strategic Stability ◽  
The Us ◽  
The Status ◽  
The Cold War

Th? paper focuses on the research of general possibilities and limitations of the multilateralization of the strategic arms control negotiations and particularly the inclusion of China in these negotiations because, during 2019 and 2020, the US conditioned the extension of the New START Treaty with China?s involvement in the trilateral strategic arms control negotiations. By doing so, the US recognised China as an important factor influencing the maintenance of strategic stability and possibilities for further reduction of strategic arms. The main hypothesis is the claim that the limitations still overcome the possibilities regarding the multilateralization of the strategic arms control negotiation, and that the prospects of involving China in this kind of negotiation remain minimal. This hypothesis was tested through theoretical deliberation based on the notion of strategic stability, and its transformation during the Cold War until today, as well as on four indicators or preconditions of China?s involvement in the strategic arms control, which are: 1) quantitative reduction of the number of nuclear arms of the US and Russia to China?s level; 2) decrease of the role of nuclear weapons in the national security and defense strategies of the great powers; 3) decrease of the role of nuclear weapons as the status symbol of the great power or superpower and 4) conclusion of the multilateral international agreement (not trilateral) on limitations on the use of nuclear weapons. The author uses the methods of content and discourse analysis, as well as the comparative method. The author concludes that the absence of the intention of the US and Russia to further reduce their strategic arms and decrease the role of nuclear weapons in their security and defense strategies, as well as the absence of consent on which parties or actors should be included in the arms control talks and China?s general suspicion about the effectiveness of the arms control agreements, influence China not to take part on any strategic arms control talks at this moment.

scholarly journals Transcaucasia: Towards a New Explosion?

2018 ◽  
Vol 9 (5) ◽  
pp. 59-76
Author(s):  
V. M. Mukhanov
Keyword(s):  
National Development ◽  
Regional Powers ◽  
South Ossetia ◽  
Internal Conflicts ◽  
Conflict Zone ◽  
The Us ◽  
The Status ◽  
Complex Landscape ◽  
The Government

The article attempts to analyze the current situation in Transcaucasia and identify the main actors, factors of influence and forces that shape the processes of domestic development in a number of republics of the region. The author comes to the conclusion that the region is in a state of “cooldown”, after 25 years of almost continual instability which, in turn, was a source of numerous internal conflicts. However, broad analysis of internal situation in the states of Transcaucasia with the inclusion of foreign influences shows a more complex landscape. Major players, such as the US and Russia, avoid increasing their presence in the region, which opens a wideWINDOW of opportunities for regional powers, such as Turkey and Iran. Against the background of decreasing interest in Transcaucasia by the world leaders, the region is returning to its historical status as a periphery. This process is characterized by a reduction in the influence of foreign actors and a rise in the role of the factors that cause general instability. These include, first and foremost, unresolved conflicts, unstable political, social and economic situation at home and specific political behaviors displayed by local elites. The April war of 2016 in Nagorno-Karabakh indicates a violation of the status quo and may lead to a high probability of new clashes in the conflict zone. The war highlighted a complex set of problems faced by Armenia and Azerbaijan in recent years. In both countries, against a backdrop of degrading economies, there is a growing split between the government and the society, as well as tensions within the elites. Similar processes are on the rise in Georgia. The situation in Abkhazia and South Ossetia is somewhat different, as the two countries could be classified as periphery to a periphery, and thus are developing in isolation from the common Caucasian agenda. Nevertheless, these countries also show a complex set of internal contradictions which tend to break out from time to time. This is symptomatic of a serious challenge facing the region. The countries that emerged on the other side of the Caucasus Mountains since 1991 are still searching for optimal models of national development.

scholarly journals The potential crucial role of COX-1 inhibition and/or Aspirin triggered lipoxins and resolvins in amelioration of COVID-19 mortality

2021 ◽  
Author(s):  
Mina Kelleni
Keyword(s):  
Mechanical Ventilation ◽  
Hospital Mortality ◽  
Real Life ◽  
Life Saving ◽  
Molecular Interpretation ◽  
Inflammatory Drugs ◽  
Cox 2 ◽  
Cox 1 ◽  
Reduced Risk

Aspirin has been recently suggested to be independently associated with reduced risk of mechanical ventilation, ICU admission and in-hospital mortality of COVID-19. However, we claim that the molecular interpretation of these important results was not scientifically valid and we provide our academic interpretation that is also basing on our real-life practice using non-steroidal anti-inflammatory drugs in management of COVID-19 and we suggest that inhibition of COX-1 and/or COX-2 enzymes might play a life saving role in COVID-19 management and we further discuss the potential of aspirin triggered lipoxins and resolivns in the same context.

scholarly journals How students view the role of the textbook nature and society in the adoption of social contents

2019 ◽  
Vol 51 (1) ◽  
pp. 128-161
Author(s):  
Aleksandra Trbojevic ◽  
Svetlana Spanovic ◽  
Vlasta Hus
Keyword(s):  
Qualitative Methodology ◽  
Real Life ◽  
School Students ◽  
Social Phenomena ◽  
The Real ◽  
Starting Point ◽  
Life Context ◽  
Nature And Society

The paper presents the results of a study of the opinion of the fourth grade primary school students (N=60) from Sombor, Serbia, about the role of the textbook Nature and Society in the adoption of social contents. The aim of the study is to determine students? opinions about how the textbook assists them in adopting social contents and how this knowledge can be useful in the real life context, which can be a relevant starting point for improving the quality of textbooks. Qualitative methodology was used to analyse the obtained data. Focus group discussions pointed to problems about the presentation of social contents in the textbooks: extensive texts that must be memorised; the lack of explanations in the text; insufficient coherence of the text, which is the reason why the adoption of social contents require assistance in the interpretation of the text. Moreover, there is a problem in the relation between the text and visual displays; the examples given do not sound familiar to students, the text is not related to the real life context, which limits the usability of social knowledge adopted from the textbook. The students? answers refer to key standards of the textbook quality (the quality of the contents, the quality of the didactic design, the quality of the language used in the textbook), and indicate that the textbook that students use does not contribute to the process of learning complex social phenomena.

The global political economy of the addictive industries

2017 ◽  
Author(s):  
David Miller ◽  
Claire Harkins ◽  
Matthias Schlögl ◽  
Brendan Montague
Keyword(s):  
Government Policy ◽  
Legal Status ◽  
Corporate Strategy ◽  
Contemporary World ◽  
Opium Trade ◽  
Addictive Substance ◽  
The Us ◽  
The Status ◽  
The Impact

The chapter examines the varying ways ‘addiction’ has been conceived and the impact of this on both corporate strategy and government policy. It examines the profit-oriented strategies of addiction related industries, the networks they construct to manage policy questions and the varying levels of governance at which corporations operate in the contemporary world. It is argued that the legal status of a particular addictive substance or behaviour has crucial though sometimes unrecognized effects on the ways in which it is traded and consumed. The chapter then includes case studies of the status of alcohol under prohibition and the Opium Wars before going on to examine the role of the US and UK governments in relation to the opium trade in contemporary Afghanistan. The chapter concludes by pointing to similar issues that are faced in policy terms in relation to both legal and illegal addictive substances and behaviours.

scholarly journals An analysis of Pak-US Relations after Pentagon 2011 Attacks

2019 ◽  
Vol 5 (3) ◽  
Author(s):  
Ghulam Muhammad Nagra ◽  
Ghulam Mustafa ◽  
Muhammad Imran
Keyword(s):  
National Interests ◽  
Security Issues ◽  
Political Relations ◽  
The Us ◽  
The Status ◽  
History Of ◽  
Utmost Care ◽  
Political Differences ◽  
Relationship Of

Islamabad’s relations with the Washington have had a chequered history. Socio-economic, political differences and national interests exacerbated by diplomatic ineptitude, as well as the obstacles inherent in relations between a developing country and a superpower, have all united to make it so, while strategic compulsions and geo-political relations on both sides have forced to bring the two countries closer. This should be emphasized that the chequered history of Pak-US relations, the shifting emphasis and the changing proclivities of the US administration and public, the nature and the constraints of the US commitment to Pakistan’s security, all make it absolutely imperative for Pakistan to take every step with the utmost care. Pakistan should realize that Washington policy on security issues could probably rebound to Islamabad’s benefit currently, but definitely not on all times in the future, as there are difficult options ahead for both Islamabad and Washington on basic strategic interests. However 9/11 incident and war on terror took back the warmth relationship of 1950s decades. Again Pakistan is playing the role of front line state to eradicate the menace of terrorism from the world and restore peace and stability in the region with the collaboration of USA and its allied forces, even Pakistan is enjoying the status of non-NATO ally.

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