scholarly journals Three-dimensional analysis of mandibular functional units in adult patients with unilateral posterior crossbite: A cone beam study with the use of mirroring and surface-to-surface matching techniques

2019 ◽  
Vol 89 (4) ◽  
pp. 590-596 ◽  
Author(s):  
Rosalia Leonardi ◽  
Simone Muraglie ◽  
Orazio Bennici ◽  
Costanza Cavallini ◽  
Concetto Spampinato
Keyword(s):  
Dominant Role ◽  
Three Dimensional ◽  
Control Sample ◽  
The Body ◽  
Adult Patients ◽  
Cone Beam ◽  
Control Group ◽  
Mandibular Ramus ◽  
Functional Units ◽  
Matching Techniques

ABSTRACT Objectives: To use three-dimensional (3D) mirroring and surface-to-surface techniques to determine any differences in mandibular functional unit shape and morphology between the crossbite side and non-crossbite side in adult patients with posterior unilateral crossbite who had not received any corrective treatment for malocclusion. Materials and Methods: Cone-beam computed tomography (CBCT) records from 24 consecutive adult white patients (mean age, 27.5 years; range 22.6–39.7 years; 14 women and 10 men) seeking treatment for maxillary transverse deficiency were assessed in this study. The control group comprised CBCT scans from age- and sex-matched patients. Segmentation masks were generated to obtain 3D surface mesh models of the mandibles and analyze the six skeletal functional units, which were further analyzed with reverse engineering software. Results: Statistically significant differences in the mean surface distance when comparing the study sample and the control sample were found at the condylar process, mandibular ramus, angular process (P ≤ .0001), and alveolar process (P ≤ .01); no statistically significant differences were found for the coronoid process, the chin, and the mandibular body (P ≥ .5). Conclusions: The condylar, angular, and alveolar processes plus the mandibular ramus appear to play a more dominant role than did the body, the coronoid, and the chin units in the asymmetry of the mandible in patients with unilateral crossbite.

Temporal bone Pneumatization in Otosclerosis

2008 ◽  
Vol 139 (6) ◽  
pp. 850-853 ◽  
Author(s):  
Daniel T. Ganc ◽  
Robert W. Jyung
Keyword(s):  
Temporal Bone ◽  
Statistical Significance ◽  
Three Dimensional ◽  
Neck Surgery ◽  
Adult Patients ◽  
Control Group ◽  
Test Analysis ◽  
Temporal Bone Pneumatization ◽  
History Of ◽  
Temporal Bones

Objectives To determine whether there is a difference in the pneumatization of temporal bones with otosclerosis versus normal temporal bones. Methods A retrospective study of 46 ears from 24 adult patients with otosclerosis and 64 ears from 47 adult patients in a control group. The study group included temporal bone CT scans available from patients with otosclerosis. The control group consisted of patients who had temporal bone CTs for reasons likely unrelated to a history of middle ear disease. Data were obtained with a virtual reality system that allows three-dimensional manipulation and analysis. Results The temporal bone pneumatization for the otosclerosis group was 4.82 ± 2.27 cm3 vs 6.06 ± 2.71 cm3 for the control group. Two-sample t test analysis revealed no statistical significance ( P = 0.059) between pneumatization in the control vs otosclerosis groups. Conclusion There is no difference in temporal bone pneumatization between patients with otosclerosis and a control population. Therefore, temporal bone pneumatization by itself is not an adequate explanation for the apparent protective effect of otosclerosis against otitis media. © 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.

scholarly journals Use of a Single Wearable Sensor to Evaluate the Effects of Gait and Pelvis Asymmetries on the Components of the Timed Up and Go Test, in Persons with Unilateral Lower Limb Amputation

Sensors ◽  
2021 ◽  
Vol 22 (1) ◽  
pp. 95
Author(s):  
Maria Stella Valle ◽  
Antonino Casabona ◽  
Ilenia Sapienza ◽  
Luca Laudani ◽  
Alessandro Vagnini ◽  
...  
Keyword(s):  
Gait Cycle ◽  
Inertial Sensor ◽  
Three Dimensional ◽  
The Body ◽  
Limb Amputation ◽  
Control Group ◽  
Timed Up And Go ◽  
Physical Mobility ◽  
Group A ◽  
First Time

The Timed Up and Go (TUG) test quantifies physical mobility by measuring the total performance time. In this study, we quantified the single TUG subcomponents and, for the first time, explored the effects of gait cycle and pelvis asymmetries on them. Transfemoral (TF) and transtibial (TT) amputees were compared with a control group. A single wearable inertial sensor, applied to the back, captured kinematic data from the body and pelvis during the 10-m walk test and the TUG test. From these data, two categories of symmetry indexes (SI) were computed: One SI captured the differences between the antero-posterior accelerations of the two sides during the gait cycle, while another set of SI quantified the symmetry over the three-dimensional pelvis motions. Moreover, the total time of the TUG test, the time of each subcomponent, and the velocity of the turning subcomponents were measured. Only the TF amputees showed significant reductions in each SI category when compared to the controls. During the TUG test, the TF group showed a longer duration and velocity reduction mainly over the turning subtasks. However, for all the amputees there were significant correlations between the level of asymmetries and the velocity during the turning tasks. Overall, gait cycle and pelvis asymmetries had a specific detrimental effect on the turning performance instead of on linear walking.

scholarly journals Mechanobehavior and mandibular ramus length in different facial phenotypes

2020 ◽  
Vol 90 (6) ◽  
pp. 866-872
Author(s):  
Paige Covington Riddle ◽  
Jeffrey C. Nickel ◽  
Ying Liu ◽  
Yoly M. Gonzalez ◽  
Luigi M. Gallo ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cluster Analysis ◽  
Informed Consent ◽  
Cone Beam Computed Tomography ◽  
Three Dimensional ◽  
Cone Beam ◽  
Mandibular Ramus ◽  
Mandibular Plane ◽  
Post Hoc ◽  
Polynomial Regressions

ABSTRACT Objectives To test the hypotheses that mechanobehavior scores (MBS) were correlated with mandibular ramus lengths (Co-Go) and differed between facial phenotypes. Materials and Methods Subjects gave informed consent to participate. Co-Go (mm), mandibular plane angles (SN-GoGn, °), and three-dimensional anatomy were derived from cephalometric radiography or cone beam computed tomography. Temporomandibular joint (TMJ) energy densities (ED) (mJ/mm3) were measured using dynamic stereometry and duty factors (DF) (%) were measured from electromyography, to calculate MBS (= ED2 × DF,) for each TMJ. Polynomial regressions, K-means cluster analysis, and analysis of variance (ANOVA) with Tukey post-hoc tests were employed. Results Fifty females and 23 males produced replete data. Polynomial regressions showed MBS were correlated with Co-Go (females, R2 = 0.57; males, R2 = 0.81). Cluster analysis identified three groups (P < .001). Dolichofacial subjects, with shorter normalized Co-Go, clustered into two subgroups with low and high MBS compared to brachyfacial subjects with longer Co-Go. SN-GoGn was significantly larger (P < .03) in the dolichofacial subgroups combined (33.0 ± 5.9°) compared to the brachyfacial group (29.8 ± 5.5°). Conclusions MBS correlated with Co-Go within sexes and differed significantly between brachyfacial and dolichofacial subjects.

scholarly journals 3D evaluation of mandibular skeletal changes in juvenile arthritis patients treated with a distraction splint: A retrospective follow-up

2016 ◽  
Vol 86 (5) ◽  
pp. 846-853 ◽  
Author(s):  
Maria Florinda Otero González ◽  
Thomas Klit Pedersen ◽  
Michel Dalstra ◽  
Troels Herlin ◽  
Carlalberta Verna
Keyword(s):  
Three Dimensional ◽  
3D Models ◽  
Joint Involvement ◽  
Control Group ◽  
Variable Response ◽  
Mandibular Ramus ◽  
Functional Appliance ◽  
Affected Side ◽  
Before And After ◽  
Condylar Displacement

ABSTRACT Objective:  To evaluate three-dimensional (3D) condylar and mandibular growth in patients with juvenile idiopathic arthritis (JIA) with unilateral temporomandibular joint involvement treated with a distraction splint. Materials and Methods:  Cone-beam computed tomography (CBCT) scans were taken for 16 patients with JIA with unilateral TMJ involvement before treatment (T0) and 2 years after treatment (T1). All patients received orthopedic treatment with a distraction splint. Eleven patients without JIA who were undergoing orthodontic treatment without a functional appliance or Class II mechanics and who had taken CBCT scans before and after treatment, served as controls. Reconstructed 3D models of the mandibles at T0 and T1 were superimposed on stable structures. Intra- and intergroup growth differences in condylar and mandibular ramus modifications and growth vector direction of the mandibular ramus were evaluated. Results:  In all patients with JIA there were asymmetric condylar volume, distal and vertical condylar displacement, and ramus length differences that were smaller on the affected side. Condylar displacement was more distal and less vertical in the JIA group than in the control group. A larger distal growth of the condylar head and a more medial rotation of the ramus on the affected side were found in the JIA group. Conclusion:  The orthopedic functional treatment for patients with JIA allows for condylar adaptation and modeling, thereby hindering, although with a widely variable response, a further worsening of the asymmetry. Unilateral affection has a possible influence on the growth of the nonaffected side.

scholarly journals Reduced Cerebral Fluoro-l-Dopamine Uptake in Adult Patients Suffering from Phenylketonuria

2007 ◽  
Vol 28 (4) ◽  
pp. 824-831 ◽  
Author(s):  
Christian Landvogt ◽  
Eugen Mengel ◽  
Peter Bartenstein ◽  
Hans Georg Buchholz ◽  
Mathias Schreckenberger ◽  
...  
Keyword(s):  
Competitive Inhibition ◽  
Elevated Serum ◽  
Graphical Analysis ◽  
The Body ◽  
Adult Patients ◽  
Control Group ◽  
Decarboxylase Activity ◽  
Large Neutral Amino Acid ◽  
Time Activity ◽  
The Brain

Deficiency of phenylalanine hydroxylase activity in phenylketonuria (PKU) causes an excess of phenylalanine (Phe) throughout the body, predicting impaired synthesis of catecholamines in the brain. To test this hypothesis, we used positron emission tomography (PET) to measure the utilization of 6-[18F]fluoro-l-dopamine (FDOPA) in the brain of adult patients suffering from PKU and in healthy controls. Dynamic 2-h long FDOPA emission recordings were obtained in seven adult PKU patients (five females, two males; age: 21 to 27 years) with elevated serum Phe levels, but lacking neurologic deficits. Seven age-matched, healthy volunteers were imaged under identical conditions. The utilization of FDOPA in striatum was calculated by linear graphical analysis ( k3S, min−1), with cerebellum serving as a nonbinding reference region. The time to peak activity in all brain time—radioactivity curves was substantially delayed in the PKU patients relative to the control group. The mean magnitude of k3S in the striatum of the PKU patients (0.0052±0.0004 min−1) was significantly lower than in the control group (0.0088±0.0009 min−1) ( P<0.001). There was no significant correlation between individual serum Phe levels and k3S. The unidirectional clearance of FDOPA to brain was impaired in adult patients suffering from PKU, presumably reflecting the competitive inhibition of the large neutral amino acid carrier by Phe. Assuming this competition to be spatially uniform, the relationship between striatum and cerebellum time—activity curves additionally suggests inhibition of DOPA efflux, possibly also due to competition from Phe. The linear graphical analysis shows reduced k3S in striatum, indicating reduced DOPA decarboxylase activity.

scholarly journals THE TREATMENT OF THE I-II SТAGES PRESSURE ULCERS WITH MACERATION, LOCAL EXEMATISATION AND DESQUAMATION OF THE EPIDERMIS: SOME SPECIFICS OF MANUFACTURING AND USE, ANALYSIS OF CLINICAL CASES

2020 ◽  
Vol 1 (39) ◽  
Author(s):  
A. R. Vergun ◽  
M. B. Kalytovska ◽  
A. V. Yutanova ◽  
V. V. Kulchytskyi ◽  
O. M. Vergun ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Pressure Ulcers ◽  
Control Sample ◽  
Main Group ◽  
The Body ◽  
Stage I ◽  
Control Group ◽  
Complex Treatment ◽  
Prepared Powder ◽  
Antiseptic Treatment

It is known that the main causes of decubital ulcers (bedsores) are ischemia and neurotrophic soft tissue pathology caused by chronic local compression, nutritional disorders, urinary and fecal incontinence, metabolic disorders. Significant risk factors are the presence of diabetes mellitus, a condition after suffering a cerebral circulation disorder, and other neurological pathology, in patients with insufficient or inadequate care. In addition to decompression of problem areas, periodic changes in the spatial position of the body in combination with antiseptic treatment in complex therapy should take into account the nutritional state, circulation, microcirculation and oxygenation in tissues, skin moisture (excessive humidity increases the risk), neurodegeneration, the stage of process, local diaper rash and maceration. The aim of the work. To optimize and improve the results of treatment of stage I-II bedsores with diaper rash, maceration, exematisation and epidermis desquamation by local therapy using clinoptilolite-based powders and to substantiate the prospects of using this method in clinical practice. The main study group over 3-year period consisted of the results of complex treatment of 28 patients, age 72-87 years: 17 women and 11 men with I-II stages of bedsores with diaper rash, maceration, local exematisation and desquamation of the epidermis and formation of superficial ulcer. The control sample consisted of the results of the treatment of 32 patients with decubital ulcers I and II stages, who were treated inpatient in the palliative care departament of the municipal non-profit enterprise "4th City Clinical Hospital" in Lviv with the use of antiseptic remediation, use of streptocid and metronidazole containing powder according to generally accepted recommendations, clinical strategies, and local protocols.Patients in the main group performed sequential repair of the wound surface with a 3% solution of hydrogen peroxide, 20% chlorhexidine bigluconate solution and sprinkling extratemporally prepared powder containing fucorcin (17 patients) or brilliant green (11 other observations). Patients in the control group were sequentially sanitized with a 3% solution of hydrogen peroxide, 1% polyvidone iodine solution, and an extratemporally prepared powder, which, in addition to the adsorbent, contained powdered white streptocide and powdery metronidasole. During daily dressings repeated repairs were carried out – washing with antiseptics of maceration sites, drying with sterile gauze wipes and filling with powder. Patients with type II diabetes have insulin resistance and deviations from laboratory parameters. The criterion for the effectiveness of care and treatment was to reduce exudation with marginal epithelialization, and (or) crust formation. In the patients of the main group, the rate of healing of wounds and macerated areas was 4.8±0.12%, in the control group – 3.2±0.25% (χ2=28.62, p<0,01). In patients of the main group with cytological examination on 3, 5 and 12 days after the initial debridement in the smears of maceration areas consistently decreased the leukocytes, appeared macrophages and fibroblasts. In the control group at 5 days after primary debridement, segmental leukocytes were prevailed, cytological signs of regeneration were less pronounced (degree of exposure, χ2=31.12, significance level, p<0.01). On day 15, we observed the correction of sites of bedsores I and II stages with maceration and local epidermis desquamation in all patients of the main group and 60.71% of the of the control group. It is stated that clinoptilolite actively adsorbs of the wound secretions and bacterial toxins from the maceration surface and superficial I and II stages decubital ulcers, releases into the wound pre-adsorbed antiseptics, which are part of the proposed powders and have a pronounced antibacterial development, when is optimal for reparative processes and the healing environment that promotes healing of the superfitial pressure ulcers.Key words: pressure ulcers, stage I-II bedsores, diaper rash with maceration sites, exematisation and desquamation, clinoptilolite-containing powder, complex treatment

Evaluation of mandibular symmetry and morphology in adult patients with unilateral posterior crossbite: a CBCT study using a surface-to-surface matching technique

2020 ◽  
Vol 42 (6) ◽  
pp. 650-657 ◽  
Author(s):  
Rosalia Leonardi ◽  
Simone Muraglie ◽  
Antonino Lo Giudice ◽  
K S Aboulazm ◽  
R Nucera
Keyword(s):  
Three Dimensional ◽  
Adult Patients ◽  
Surface Matching ◽  
Control Group ◽  
Gonial Angle ◽  
Engineering Software ◽  
Mandibular Asymmetry ◽  
Deviation Analysis ◽  
Matching Technique ◽  
Surface Deviation

Summary Objectives To investigate mandibular morphology in adults affected by posterior unilateral crossbite (PUXB) and to evaluate the hemi mandibular volumes from the crossbite (CB) and non-CB sides of the same patients. Methods Thirty-eight cone beam computed tomography (CBCT) images were consecutively recruited and the Digital Imaging and Communications in Medicine (DICOM)-formatted scans were volume rendered into a surface three-dimensional (3D) mesh model and volumes to obtain the 3D model of the mandibular bone. To achieve the surface point-to-point analysis of the mandibular models, a reverse engineering software was used. The same procedure was performed for an age-matched control group (19 CBCT images). Results Total mandibular volume showed a difference of 2.46 cm3 between patients and controls, which was not statistically significant. A mean difference of 1.53 cm3 was found comparing the hemi mandibular volumes from the CB and non-CB sides of PUXB patients, this difference was statistically significant (P ≤ 0.01). Findings for the surface-to-surface deviation analysis, demonstrated a higher percentage of mismatch in patients PUXB, over 10% at 0.5 mm tolerance level. Limitations Limitations are related to the intrinsic surfaces matching methodology, that make difficult to evaluate discrepancies among different mandibular anatomical units. Conclusion Adult patients affected by PUXB show a greater mandibular structural asymmetry compared to controls because of a lower matching percentage obtained from the surface-to-surface matching technique. Implications Treatment of adult patients affected by PUXB should take into consideration the possibility of a mild mandibular asymmetry mainly localized at the condyle and gonial angle levels.

scholarly journals Effects of Changes in the Frankfort Horizontal Plane Definition on the Three-Dimensional Cephalometric Evaluation of Symmetry

2020 ◽  
Vol 10 (22) ◽  
pp. 7956
Author(s):  
Utkarsh Mangal ◽  
Jae Joon Hwang ◽  
Heon Jo ◽  
Sung Min Lee ◽  
Yun-Hoa Jung ◽  
...  
Keyword(s):  
Spatial Orientation ◽  
Horizontal Plane ◽  
Three Dimensional ◽  
Adult Patients ◽  
Cone Beam ◽  
Tomographic Images ◽  
Future Studies ◽  
Computed Tomographic ◽  
3D Cephalometry ◽  
Frankfort Horizontal Plane

The plane formed by the intersection of bilateral porions (PoR and PoL) and left orbitale (OrL) is conventionally defined as the Frankfort horizontal (FH) plane. We aim to test the influence of the FH plane definition on a 3D cephalometric assessment. We selected 38 adult patients (20 males, 18 females; average age: 22.87 ± 5.17 years) without any gross asymmetry from retrospective records and traced and analyzed their cone-beam computed tomographic images. The findings were categorized into the following four groups: FH1: conventional; FH2: PoR, PoL, right orbitale (OrR); FH3: OrR, OrL, PoL; FH4: OrR, OrL, PoR. The average menton (Me) deviation from the MSP was statistically significant for the FH1 group (0.56 ± 0.27 mm; p < 0.001), compared to the FH3 (1.37 ± 1.23 mm) and FH4 (1.33 ± 1.16 mm) groups. The spatial orientation level (SOL) of the FH plane showed a marked difference (p < 0.05) between the FH2 (0.602° ± 0.503°) and FH4 (0.944° ± 0.778°) groups. The SOL of the MSP was comparatively small (p < 0.001) for FH2 (0.015° ± 0.023°) in comparison to both FH 3 (0.644° ± 0.546°) and FH 4 (0.627° ± 0.516°). Therefore, the FH plane definition can significantly influence the interpretation of cephalometric findings. Future studies should focus on standardization to improve the reliability and reproducibility of 3D cephalometry.

scholarly journals Dynamic scapulohumeral rhythm: Comparison between healthy shoulders and those with large or massive rotator cuff tear

2020 ◽  
Vol 28 (3) ◽  
pp. 230949902098177
Author(s):  
Naoya Kozono ◽  
Naohide Takeuchi ◽  
Takamitsu Okada ◽  
Satoshi Hamai ◽  
Hidehiko Higaki ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Rotator Cuff Tear ◽  
External Rotation ◽  
Three Dimensional ◽  
Control Group ◽  
Scapular Kinematics ◽  
Cuff Tear ◽  
And Control ◽  
Matching Techniques ◽  
Scapular Plane

Introduction: Assessment of scapular kinematics and the dynamics of the scapulohumeral rhythm (SHR) would be important for understanding pathologies of the shoulder and to inform treatment. Our aim in this study was to evaluate the SHR and scapular kinematics in patients with a rotator cuff tear (RCT), compared to a control group with healthy shoulders using image-matching techniques. Materials and Methods: The shoulder kinematics of large or massive RCT patients were evaluated and compared to a control group with healthy shoulders. Radiographic surveillance was performed throughout the full range of external rotation and scapular plane abduction. Computed tomography imaging of the shoulder complex was performed, with three-dimensional image reconstruction and matching to the radiographs to measure three-dimensional positions and orientations. SHR and angular values of the scapula were measured. Results: Scapular external rotation in the late phase of external rotation movement was greater in the RCT group than in the control group ( p < 0.05), but with no difference in the SHR. During scapular plane abduction, there were significant differences in SHR, scapular posterior tilt and scapular upward rotation between the RCT and control group ( p < 0.05). Conclusions: Regarding clinical relevance, this study clarified the differences of SHR and angular values of the scapula between the RCT and control group. These results underline the importance of assessment the SHR and scapular kinematics in individuals with a RCT. RCT is associated with specific compensation in the kinematics of the scapula and SHR during external rotation and scapular plane abduction, which could inform treatment.

Scanning electron microscopy of freeze-fractured prescapular lymph node of caprine

1984 ◽  
Vol 42 ◽  
pp. 244-245
Author(s):  
O. Faroon ◽  
F. Al-Bagdadi ◽  
T. G. Snider ◽  
C. Titkemeyer
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Lymphatic System ◽  
Three Dimensional ◽  
Meat Products ◽  
The Body ◽  
Morphological Data ◽  
The World ◽  
Cellular Constituent ◽  
Scanning Electron

The lymphatic system is very important in the immunological activities of the body. Clinicians confirm the diagnosis of infectious diseases by palpating the involved cutaneous lymph node for changes in size, heat, and consistency. Clinical pathologists diagnose systemic diseases through biopsies of superficial lymph nodes. In many parts of the world the goat is considered as an important source of milk and meat products.The lymphatic system has been studied extensively. These studies lack precise information on the natural morphology of the lymph nodes and their vascular and cellular constituent. This is due to using improper technique for such studies. A few studies used the SEM, conducted by cutting the lymph node with a blade. The morphological data collected by this method are artificial and do not reflect the normal three dimensional surface of the examined area of the lymph node. SEM has been used to study the lymph vessels and lymph nodes of different animals. No information on the cutaneous lymph nodes of the goat has ever been collected using the scanning electron microscope.

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