scholarly journals Profile Matching of Brazilian Birth and Mortality Records where microcephaly is recorded.

Author(s):  
Antony Stevens ◽  
Roberta Maria Leite Costa ◽  
Dacio de Lyra Rabello Neto

ABSTRACT BackgroundIn Profile Matching the term "Profile" means that the information available about an individual could be the same as that available for some other individuals. Reduced versions of birth and mortality records are made publicly available by the Brazilian Ministry of Health and this study covers the years 1996 to 2013. Date of birth, sex and municipality of residence are available in both types of record, so their combination could be studied as a pseudo-identifier. The municipality could be different at the two events so the results outlined here must be seen as a first cut. MethodThe ICD 10 code for microcephaly is Q02. Among the mortality records where Q02 was recorded either as a basic cause or in one of the other lines there were 1676 combinations of the three variables. All but three of them were unique and the remaining three each occcurred with only two records. For 1324 of these records the year of birth was between 1996 and 2013 so that we could reasonably expect these combinations of values among the birth records. However, there were only 204 birth records with combinations that matched and where Q02 was recorded. Possible reasons for the difference could include i) underreporting of births, ii) the failure to detect microcephaly at birth registration and iii) the possibility that microcephaly can only be securely identified sometime after a birth would normally be registered. ResultsAmong the birth records there were 2349 combinations where Q02 was mentioned as a birth anomaly. All but seven of them were unique and the remaining seven each occcurred with only two records. Corresponding to these combinations there were 1416 combinations found among the mortality records. These were found in 2149 records. However in only 541 of the mortality records was there a mention of Q02. It appears as the basic cause of death in 204 of these 541 records. It could be that such a small number of deaths attributed to Q02 is consistent with best medical opinion. ConclusionIt is easy to dismiss these apparent discrepancies as poor recording. Some of it may be, but it could be that doctors were faithful to what they observed. The next step is have a clear picture of what was recorded, like other types of birth defect, when Q02 was not observed in both records of a match.

2020 ◽  
Vol 6 (2) ◽  
pp. 4-7
Author(s):  
G. A. Aleksandrova ◽  
D. Sh. Vaysman

Aim. For the purpose of ensuring the reliability of national mortality statistics, the present regulations set out to generalize current information on the preparation of primary medical documentation on the basis of requirements for filing death certificates, ICD-10 rules and recommendations by the Russian Ministry of Health.Material and methods. Existing requirements for filing death certificates, ICD-10 rules updated by WHO in 1996–2019 and recommendations by the Russian Ministry of Health were analysed.Results. The preparation of primary medical documentation, formulation of the concluding clinical, pathological, anatomical and forensic post-mortem diagnosis, issuance of death certificates, selection and coding of the primary cause of death should be carried out in accordance with the unified ICD-10 rules. Postmortem diagnosis should correspond to Volume 3 of ICD-10.Due to the pandemic of a new coronavirus infection, referred to as COVID-19, in 2019, WHO introduced changes to the ICD-10. COVID-19 was included in ICD-10 chapter XXII and received the codes of U07.1 and U07.2. COVID-19-accosiated deaths were divided into those where COVID-19 is determined to be the primary cause of death and those where COVID-19 falls into the category “other” causes.COVID-19 with fatal complications is most frequently selected as the primary cause of death in acute conditions, with concurrent chronic diseases (cancer, diabetes, chronic forms of ischemic and cerebrovascular diseases, etc.) being indicated as “other” causes of death in Part II of the death certificate. In the presence of trauma, poisoning, bleeding and conditions requiring emergency medical care, these conditions are selected as the primary cause of death, with COVID-19 being recorded in part II of the certificate.Conclusion. To provide reliable statistical information about mortality rates, executive authorities require the primary medical documentation filed in strict accordance with established rules. 


Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Deepak R Nair ◽  
Abhyuday Chauhan ◽  
Dhananjay Vaidya

Background: Asian Indians (AI) in the US are known to have a high prevalence of atherosclerotic diseases and diabetes mellitus (DM). However, it is not known if these two cluster as causes of death in AI compared to the rest of US population. Methods: Using 2017 Multiple Cause-of-Death Data from the National Centre for Health Statistics, we included deaths at age ≥ 45 years among US residents where AI vs not-AI could be ascertained (n = 7940 AI; n = 2.6 million not-AI). DM (ICD-10 range: E10-E14) and any atherosclerosis (either of: ischemic heart disease, ischemic stroke, atherosclerosis; ICD-10 range: I20-I25, I69, I70, respectively) as contributing causes of death were identified in AI and not-AI. We calculated dichotomous tetrachoric correlation (Rho) between DM and atherosclerosis as co-occurring contributing causes. To examine whether this association differed by age decade and sex, we calculated the difference in fraction of deaths with DM in those with atherosclerosis versus those without atherosclerosis as a co-occurring cause of death. Results: There were 114,210 atherosclerosis deaths and 24,331 DM deaths in 2017 in the sample. DM and atherosclerosis as contributing causes correlated more strongly in AI (Rho = 0.36, p < 0.001) as compared to not-AI (Rho = 0.31, p < 0.001; difference between groups, p < 0.001). The excess fraction of deaths due to DM when atherosclerosis also contributed vs when atherosclerosis did not contribute was higher in AI men of all ages and in most ages for AI women, except for a group where AI death numbers were smaller (Figure). Conclusion: Our findings highlight the increased burden of co-occurring DM and atherosclerotic disease together contributing as causes of death in AI compared to not-AI in the US. Public health strategies targeted to AI should focus on prevention and clinical treatment of both conditions jointly, in both men and women, especially during young adulthood and middle age.


Author(s):  
Stuart Jarvis ◽  
Lorna Fraser

ABSTRACTObjectivesTo compare methods of estimating prevalence of life limiting conditions (LLC) among children and young people (CYP) using (i) cause of death recorded on death certificates and (ii) diagnostic codes in routinely collected inpatient and birth records. ApproachCYP with a LLC were identified from NHS inpatient and birth records in Scotland from 1 April 2003 to 30 March 2014 using a LLC ICD-10 coding framework. The cohort was restricted to individuals who died in the study period. For each cohort member, the LLC coding framework was used to determine whether a diagnosis identified as a LLC was recorded as the underlying cause of death. For those without LLC as an underlying cause of death, the underlying cause was checked to determine whether it was related to LLC – either itself indicative of LLC when recorded on a death certificate or related to one or more of the LLCs identified in the individual’s inpatient and birth records. Finally, for those with underlying cause of death neither a LLC nor related to a LLC, the contributing causes of death were checked against the coding framework for LLC; where found, the individual was marked as having a LLC as a contributing cause of death. These analyses were undertaken for the whole cohort, per year, by age groups and by diagnostic categories. Results20436 CYP with a LLC were identified between 1 April 2009 and 31 March 2014, of which 2249 had died and had a death register record. Of these, 1291 (57%) had a LLC as underlying cause of death; 319 (14%) had an LLC-related underlying cause of death and 268 (12%) had LLC only among contributing causes of death. 371 (16%) had no indication of LLC in their death records. Recording of a LLC as underlying cause of death was lower (41%) amongst under 1 year olds and also varied widely by diagnostic group. ConclusionAround one in six of CYP identified using the coding framework as having a LLC (and almost one in five of under 1s) would not have been so identified using all causes of death in death records. More than a quarter (28%) would be missed if only underlying cause of death was used. This, combined with longer survival times, means use of death records has the potential to greatly underestimate prevalence of LLC in children and young people.


Kardiologiia ◽  
2019 ◽  
Vol 59 (7) ◽  
pp. 5-10
Author(s):  
O. M. Drapkina ◽  
I. V. Samorodskaya ◽  
D. Sh. Vaisman

Aim: to analyze the quality of completion medical certificates of death (MCD) of residents of the Tula region, in which in 2017 acute and subsequent myocardial infarction (MI) was listed as the underlying cause of death (UCD) or as multiple causes of death (MC).Materials and methods. From the electronic database (DB) of MCD of residents of Tula region for 2017 we selected all MSD in which MI was written down irrespective of a section of MCD. A total of 689 MSD (43.8% men and 56.2% women) were analyzed.Results. Mean age of the deceased was 72.6±11.3 years (men 67.25±0.62; women 76.7±9.8; p<0.001). Multimorbid pathology was registered in 31.5% of the deceased. In 77.9% of cases myocardial infarction was selected as the UCD and in 22.1% – as a complication of other diseases. Among registered MI complications were hemotamponade (24.5%), cardiogenic shock (3.6%), ventricular fibrillation (0.3%), heart failure (50.2%). Complications of MI were not listed in 3.9% of MCD. Analysis of MCD showed that their completion did not comply with established ICD-10 rules and recommendations of Ministry of Health of RF; all lines were filled out only in 1% of completed MCD. Also, problems of determining the initial cause of death when myocardial infarction occurred in the presence of multimorbid pathology were revealed.Conclusion. Mortality analysis using solely UCD leads to decreasing mortality rates from MI, and unsatisfactory quality of filling the MCD decreases the ability to identify MC, that prevents the correction of priorities in the organization of medical care. The revealed problems of coding causes of death require urgent solutions from the professional community of cardiologists, pathologists, and the Ministry of Health.


1973 ◽  
Vol 29 (02) ◽  
pp. 490-498 ◽  
Author(s):  
Hiroh Yamazaki ◽  
Itsuro Kobayashi ◽  
Tadahiro Sano ◽  
Takio Shimamoto

SummaryThe authors previously reported a transient decrease in adhesive platelet count and an enhancement of blood coagulability after administration of a small amount of adrenaline (0.1-1 µg per Kg, i. v.) in man and rabbit. In such circumstances, the sensitivity of platelets to aggregation induced by ADP was studied by an optical density method. Five minutes after i. v. injection of 1 µg per Kg of adrenaline in 10 rabbits, intensity of platelet aggregation increased to 115.1 ± 4.9% (mean ± S. E.) by 10∼5 molar, 121.8 ± 7.8% by 3 × 10-6 molar and 129.4 ± 12.8% of the value before the injection by 10”6 molar ADP. The difference was statistically significant (P<0.01-0.05). The above change was not observed in each group of rabbits injected with saline, 1 µg per Kg of 1-noradrenaline or 0.1 and 10 µg per Kg of adrenaline. Also, it was prevented by oral administration of 10 mg per Kg of phenoxybenzamine or propranolol or aspirin or pyridinolcarbamate 3 hours before the challenge. On the other hand, the enhancement of ADP-induced platelet aggregation was not observed in vitro, when 10-5 or 3 × 10-6 molar and 129.4 ± 12.8% of the value before 10∼6 molar ADP was added to citrated platelet rich plasma (CPRP) of rabbit after incubation at 37°C for 30 second with 0.01, 0.1, 1, 10 or 100 µg per ml of adrenaline or noradrenaline. These results suggest an important interaction between endothelial surface and platelets in connection with the enhancement of ADP-induced platelet aggregation by adrenaline in vivo.


Author(s):  
Philip Isett

This chapter presents the equations and calculations for energy approximation. It establishes the estimates (261) and (262) of the Main Lemma (10.1) for continuous solutions; these estimates state that we are able to accurately prescribe the energy that the correction adds to the solution, as well as bound the difference between the time derivatives of these two quantities. The chapter also introduces the proposition for prescribing energy, followed by the relevant computations. Each integral contributing to the other term can be estimated. Another proposition for estimating control over the rate of energy variation is given. Finally, the coarse scale material derivative is considered.


Metahumaniora ◽  
2017 ◽  
Vol 7 (3) ◽  
pp. 378
Author(s):  
Vincentia Tri Handayani

AbstrakFolklor yang menghasilkan tradisi lisan merupakan perwujudan budaya yang lahirdari pengalaman kelompok masyarakat. Salah satu bentuk tradisi lisan adalah ungkapan yangmengandung unsur budaya lokal dalam konstruksinya yang tidak dimiliki budaya lainnya.Ungkapan idiomatis memberikan warna pada bahasa melalui penggambaran mental. Dalambahasa Perancis, ungkapan dapat berupa locution dan expression. Perbedaan motif acuansuatu ungkapan dapat terlihat dari pengaruh budaya masyarakat pengguna bahasa. Sebuahleksem tidak selalu didefinisikan melalui unsur minimal, tidak juga melalui kata-kata,baik kata dasar atau kata kompleks, namun dapat melalui kata-kata beku yang maknanyatetap. Hubungan analogis dari makna tambahan yang ada pada suatu leksem muncul dariidentifikasi semem yang sama. Semem tersebut mengarah pada term yang diasosiasikan danyang diperkaya melalui konteks (dalam ungkapan berhubungan dengan konteks budaya).Kata kunci: folklor, ungkapan, struktur, makna idiomatis, kebudayaanAbstractFolklore which produces the oral tradition is a cultural manifestation born out theexperience of community groups. One form of the oral tradition is a phrase that containsthe elements of local culture in its construction that is not owned the other culture. Theidiomatic phrase gives the color to the language through the mental representation. InFrench, the expression can consist of locution and expression. The difference motivesreference of an expression can be seen from the influence of the cultural community thelanguage users. A lexeme is not always defined through a minimal element, nor throughwords, either basic or complex words, but can be through the frost words whose meaningsare fixed. The analogical connection of the additional meanings is on a lexeme arises fromthe identification of the same meaning. The meaning ‘semem’ leads to the associated termsand which are enriched through the context (in idiom related to the cultural context).Keywords : folklore, idioms, structure, idiom meaning, cultureI PENDAHULUAN


Author(s):  
Michel Meyer

Rhetoric has always been torn between the rhetoric of figures and the rhetoric of conflicts or arguments, as if rhetoric were exclusively one or the other. This is a false dilemma. Both types of rhetoric hinge on the same structure. A common formula is provided in Chapter 3 which unifies rhetoric stricto sensu and rhetoric as argumentation as two distinct but related strategies adopted according to the level of problematicity of the questions at stake, thereby giving unity to the field called “Rhetoric.” Highly problematic questions require arguments to justify their answers; non-divisive ones can be treated rhetorically through their answers as if they were self-evident. Another classic problem is how to understand the difference between logic and rhetoric. The difference between the two is due to the presence of questions explicitly answered in the premises in logic and only suggested (or remaining indeterminate) in rhetoric.


Author(s):  
D. T. Gauld ◽  
J. E. G. Raymont

The respiratory rates of three species of planktonic copepods, Acartia clausi, Centropages hamatus and Temora longicornis, were measured at four different temperatures.The relationship between respiratory rate and temperature was found to be similar to that previously found for Calanus, although the slope of the curves differed in the different species.The observations on Centropages at 13 and 170 C. can be divided into two groups and it is suggested that the differences are due to the use of copepods from two different generations.The relationship between the respiratory rates and lengths of Acartia and Centropages agreed very well with that previously found for other species. That for Temora was rather different: the difference is probably due to the distinct difference in the shape of the body of Temora from those of the other species.The application of these measurements to estimates of the food requirements of the copepods is discussed.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Andrés Moreno Roca ◽  
Luciana Armijos Acurio ◽  
Ruth Jimbo Sotomayor ◽  
Carlos Céspedes Rivadeneira ◽  
Carlos Rosero Reyes ◽  
...  

Abstract Objectives Pancreatic cancers in most patients in Ecuador are diagnosed at an advanced stage of the disease, which is associated with lower survival. To determine the characteristics and global survival of pancreatic cancer patients in a social security hospital in Ecuador between 2007 and 2017. Methods A retrospective cohort study and a survival analysis were performed using all the available data in the electronic clinical records of patients with a diagnosis of pancreatic cancer in a Hospital of Specialties of Quito-Ecuador between 2007 and 2017. The included patients were those coded according to the ICD 10 between C25.0 and C25.9. Our univariate analysis calculated frequencies, measures of central tendency and dispersion. Through the Kaplan-Meier method we estimated the median time of survival and analyzed the difference in survival time among the different categories of our included variables. These differences were shown through the log rank test. Results A total of 357 patients diagnosed with pancreatic cancer between 2007 and 2017 were included in the study. More than two-thirds (69.9%) of the patients were diagnosed in late stages of the disease. The median survival time for all patients was of 4 months (P25: 2, P75: 8). Conclusions The statistically significant difference of survival time between types of treatment is the most relevant finding in this study, when comparing to all other types of treatments.


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