HISTOLOGICAL CHANGES IN THE INTESTINES OF POULTRY DURING FODDER INTOXICATION

2020 ◽  
Author(s):  
E.P. Dolgov ◽  
◽  
A.A. Abramov ◽  
E.V. Kuzminova ◽  
E.V. Rogaleva ◽  
...  
Keyword(s):  
Body Weight ◽  
Histological Examination ◽  
Aflatoxin B1 ◽  
Structural Changes ◽  
Clinical Manifestations ◽  
Feed Additives ◽  
The Body ◽  
Histological Changes ◽  
Beet Pulp

The article presents the data on the study of the influence of mycotoxins combination (T-2 toxin at the concentration of 0.095 mg/kg and aflatoxin B1 in the concentration of 0.019 mg/kg) on the body of quails and the results of pharmacocorrection of toxicosis with a complex consisting of beet pulp and lecithin. Structural changes in the intestines of quais at fodder mycotoxicosis are described. The use of antitoxic feed additives in poultry led to a weakening of the action of xenobiotics, which was confirmed by an increase in the safety of poultry and increase in body weight of quails, a decrease in the clinical manifestations of intoxication, as well as in positive changes in the structure of the intestine of the poultry during histological examination.

scholarly journals System of antioxidant protection of the body of piglets under the action of feed additive “Sylimevit”

2021 ◽  
Vol 23 (104) ◽  
pp. 10-17
Author(s):  
L. V. Vyslotska ◽  
B. V. Gutyj ◽  
O. V. Kozenko ◽  
V. I. Khalak ◽  
M. V. Chornyj ◽  
...  
Keyword(s):  
Body Weight ◽  
Antioxidant Defense System ◽  
Feed Additives ◽  
The Body ◽  
Biologically Active ◽  
Feed Additive ◽  
Free Access ◽  
Direct Acting ◽  
Active Substances ◽  
Technological Stress

One of the conditions for obtaining high-quality pig products is the use of feed additives, which contain all the necessary biologically active substances, eliminating their deficiency in feed and acting as catalysts for metabolic processes in pigs. That is why the aim of the study was to study the effect of feed additive “Sylimevit” on the enzymatic and non-enzymatic parts of the antioxidant system of piglets after weaning. Two groups of piglets were formed – control and experimental, in the amount of 10 individuals in each group, selected on the principle of analogues – age, breed and body weight. During the weaning period, the piglets were kept under the sow in special machines, had constant access to the mother, and from the age of 5 days – free access to concentrated feed. Feeding of animals was carried out in accordance with the norms for a given age of pigs. Prior to the study, a clinical and physiological examination of the piglets was performed. Their general condition and activity when eating food were taken into account. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests in order to be further maintained during the period of fattening and rearing with a change in the structure of the diet, which served as technological stress for the animals. From the age of 5 days, piglets of all groups were fed pre-starter feed. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed supplement “Sylimevit” at a dose of 100 mg/kg body weight per day. Feeding piglets Silimevit feed enhances their antioxidant status. The use of this feed additive in piglets contributed to the activation of both enzymatic and non-enzymatic parts of the antioxidant defense system of piglets after weaning, as indicated by an increase in blood 35-day-old piglets superoxide dismutase activity by 26.9 % (P < 0.001), catalase – 41.1 % (P < 0.001), glutathione peroxidase – by 52.7 % (P < 0.05), glutathione reductase – by 53.5 % (P < 0.05), the content of reduced glutathione – by 75 % (P < 0.001). This is due to the fact that silimevit contains active substances such as milk thistle and vitamins, which are strong direct-acting antioxidants and directly interact with free radicals and reactive oxygen species.

scholarly journals PSVIII-28 The effect of adaptogen on the growth and development of dairy calves

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 302-302
Author(s):  
Irina Lunegova
Keyword(s):  
Body Weight ◽  
High Growth ◽  
High Growth Rate ◽  
Feed Additives ◽  
The Body ◽  
Dairy Calves ◽  
Feeding Mode ◽  
Holstein Breed ◽  
Experimental Group ◽  
Intensive Growth

Abstract For the harmonious development, intensive growth and preservation of young animals in the diet it is necessary to include various feed additives, complexes, adaptogens that enhance the metabolic processes in the body. The purpose of the study is to study the feasibility and effectiveness of the use of adaptogen in calves rations. To achieve this goal in industrial conditions, 30 calves of Holstein breed at the age of 5–7 days were selected and divided into two groups of 15 animals each. The duration of the experiment was 90 days. Calves of the experimental group in milk, and then in concentrates included adaptogen “Energy” in the amount of 250 mg / kg body weight. The control animals were fed according to the standard scheme in the farm. The feeding mode for all calves was in accordance with the growing technology. The adaptogen includes: succinic, citric acid, inulin, oligofructose, methionine, lactic acid bacteria immobilized on aluminosilicate (patent RU 2493725). The results of the experiment (table 1) showed that the inclusion of an adaptogen provided a high growth rate throughout the entire period. At the end of the experiment, the body weight of calves of the experimental group was 6.52% (P &gt; 0.05) higher compared to the control.

scholarly journals Administration of garlic and neem in broiler diet for safe meat production

2020 ◽  
Vol 48 (2) ◽  
pp. 116-126
Author(s):  
R Islam ◽  
MM Hossain ◽  
F Nargis ◽  
ME Hossain
Keyword(s):  
Body Weight ◽  
Basal Diet ◽  
Feed Additives ◽  
The Body ◽  
The Other ◽  
Control Group ◽  
Meat Production ◽  
Broiler Chicks ◽  
Treatment Groups ◽  
Broiler Production

This study was conducted to observe the effect of different administration method of garlic and neem on growth performances, feed efficiency and serum biochemical parameters for safe broiler production. The experiment was done for a period of 32 days with 384 one-day-old straight run broiler chicks. The broiler chicks were divided into six groups each of 64 birds and replicated to four subgroups each of 16 birds. The dietary groups were; control (basal diet; no additives), antibiotic (basal diet + antibiotic), garlic in feed (basal diet + 0.25% garlic powder), garlic in water (basal diet + garlic extracts), neem in feed (basal diet + 0.25% neem powder) and neem in water (basal diet + neem extracts). Results showed that the body weight and body weight gain increased significantly (P<0.05) in both the garlic and neem groups compared to the control group. Feed intake was not different (P>0.05) among the treatment groups. Garlic in feed and water and neem in feed groups showed better FCR (P<0.05) compared to the other treatment groups. There were no significant (P>0.05) difference in meat yield, bone development and dressing parameters except head and gizzard in different dietary groups. Supplementation of garlic with feed and water significantly (P<0.05) decrease cholesterol, triglyceride and LDL compared to the other groups. However, both the garlic and neem groups showed numerically higher HDL compare to the control group. There were no 0significant (P>0.05) differences in serum glucose and GPT among different treatment groups. GOT was significantly (P<0.05) lower in neem groups than that of garlic and antibiotic groups. Additive groups showed higher profitability than control group. Based on the results of the study, it may be suggested that the garlic and neem could be used both in feed and water as potential feed additives for safe broiler production. Bang. J. Anim. Sci. 2019. 48 (2): 116-126

scholarly journals «Energosil» in the diets of replacement gilts

2019 ◽  
Vol 20 (2) ◽  
pp. 153-162
Author(s):  
A. A. Suvorov ◽  
в Sh. Gayirbegov ◽  
A. S. Fedin ◽  
A. M. Guryanov
Keyword(s):  
Body Weight ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Practical Training ◽  
Optimal Dosage ◽  
Growth Energy ◽  
Experimental Group

The article gives scientific substantiation of using silicon-containing new feed additive “Energosil” for replacement gilts. The studies were conducted in pig-breeding complex of the Center for Practical Training of Agricultural Specialists in Mordovia Republic. There were three experimental groups of replacement gilts (10 animals each). The effect of various dosages of Energosil (5.0, 7.5, and 10 mg per kg of body weight) on digestibility, nutrient utilization, and animal growth energy was studied. The most optimal dosage of a new feed additive in their rations was revealed, which constituted 5 mg / kg of the animal live weight. It was established that the animals from the first experimental group, who received silicon-containing feed additives of this amount digested the nutrients of the diet better than their counterparts from the other groups. Compared to the control group, the digestibility of dry matter increased by 3.62% (p<0.05), organic matter by 3.29% (p<0.01), crude protein by 4.09% (p<0.001), fat by 4.30% (p<0.01), cellulose by 3.79% (p<0.01) and nitrogen-free extractives by 2.03% (p>0.05).Replacement gilts of the first experimental group, who were given Energosil in the amount of 5 mg / kg body weight in addition to the basic ration, retained nitrogen in their bodies by 17.1%, calcium by 55.9% and phosphorus by 69.7% more than their counterparts from the control group. It contributed to an increase in body weight of gilts from the first group compared to control counterparts by 10.8%. Increased dosages of Energosil (7.5 and 10 mg / kg body weight) also had a better effect on the growth energy of gilts compared with the control group. The feed additive in the amount of 7.5 mg kg of animal  live weight contributed to an increase in animal weight compared with control counterparts by 6.21 kg or 4.8% (p<0.05), with a third experimental group by 4.4 kg or by 3.4% (p<0.05). When given Energosil in the dosage of 10 mg/kg, the body weight of gilts from the third experimental group was higher by 1.81 kg or 1.4% (p> 0.05) compared with the control counterparts.

scholarly journals Influence of various levels of valin in the mixed fodder on the carcass composition of quails

2017 ◽  
Vol 19 (79) ◽  
Author(s):  
M. Sychov ◽  
T. Golubeva ◽  
V. Kovalchuk ◽  
Y. Poznyakovskiy
Keyword(s):  
Body Weight ◽  
Large Body ◽  
Carcass Composition ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Feed Conversion ◽  
Experimental Scheme ◽  
National University ◽  
Effective Level

The article presents the expediency of using valine in the feeding of growing quails of meat direction of productivity. The studies were conducted in the conditions of research laboratory of feed additives of National University of Life and Environmental Sciences of Ukraine. The experiment was conducted with growing Pharaoh quails. It was selected 500 daily quails. Birds were placed in 20 cages with 25 heads in each. In the formation of analog groups, the body weight of the birds was taken into account. Quails were fed full-fledged mixed fodder, which was balanced by energy and other nutrients. The feed for the quails of the control group contained the natural level of valine, and the experimental groups – additionally L-valine according to the experimental scheme. Observed a relationship between the level of valine in feed and feed conversion (R2 = 0.7359). The most effective level of valine in mixed fodder for quail, which is grown for meat, to obtain a sufficiently large body weight with a low level of feed intake per unit of growth is at 1– 21-day age – 1.68% and at 22– 35-day age – 1.23%.

scholarly journals Effects of phytonutrient-supplemented diets on the intestinal microbiota of Cyprinus carpio

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0248537
Author(s):  
Milan Feher ◽  
Peter Fauszt ◽  
Emese Tolnai ◽  
Gabor Fidler ◽  
Georgina Pesti-Asboth ◽  
...  
Keyword(s):  
Body Weight ◽  
Gastrointestinal Tract ◽  
Common Carp ◽  
Cyprinus Carpio ◽  
Feed Additives ◽  
The Body ◽  
Red Pepper ◽  
Gut Contents ◽  
Metagenomic Sequencing ◽  
Spoilage Bacteria

In the aquaculture sector, a strategy for the more efficient use of resources and proper disease control is needed to overcome the challenges of meat production worldwide. Modulation of the gastrointestinal tract microbiota is a promising approach for promoting animal health and preventing infection. This feeding experiment was conducted to discover the phytonutrient-induced changes in the gastrointestinal tract microbiota of common carp (Cyprinus carpio). Acclimatized animals aged 7 months (30 weeks) were divided randomly into five experimental groups to investigate the effects of the applied feed additives. The dietary supplements were manufactured from anthocyanin-containing processing wastes from the food industry, specifically the production of Hungarian sour cherry extract, synbiotics from fermented corn, and fermentable oligosaccharides from Hungarian sweet red pepper seeds and carotenoids from Hungarian sweet red pepper pulps, applied at a dose of 1%. The gut contents of the animals were collected at four time points throughout the 6-week study period. To track the compositional and diversity changes in the microbiota of the carp intestinal tract, V3-V4 16S rRNA gene-based metagenomic sequencing was performed. The growth performance of common carp juveniles was not significantly affected by supplementation of the basal diet with plant extracts. Phytonutrients improve the community diversity, increase the Clostridium and Lactobacillus abundances and decrease the abundances of potentially pathogenic and spoilage bacteria, such as Shewanella, Pseudomonas, Acinetobacter and Aeromonas. The phyla Proteobacteria, Tenericutes and Chlamydiae were positively correlated with the body weight, whereas Spirochaetes and Firmicutes exhibited negatively correlations with the body weight. We hypothesize that the application of phytonutrients in aquaculture settings might be a reasonable green approach for easing the usage of antibiotics.

Effect of Vasectomy and / or Adding Cuminum cyminum Seeds in the diet of Awassi Ram Lambs on their Carcasses Traits

2014 ◽  
Vol 38 (2) ◽  
pp. 79-86
Author(s):  
Tamara N. Dawood
Keyword(s):  
Body Weight ◽  
Carcass Traits ◽  
Feed Additives ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Muscle Area ◽  
Eye Muscle ◽  
The Third ◽  
Ram Lambs

     This experiment was carried out at Animal Farm, College of Veterinary Medicine, Baghdad University, from Mar. up to Sept. 2010. Twenty eight Awassi ram lambs of 4-5 months old were equally divided into four groups of similar body weight and fed 2% of concentrate diet of body weight with grazing for 3-4 hours a day. The first group (C) and the third group (V) were fed concentrate diet free of cumin seeds; while the second group (CU) and the fourth group (CV) were fed the same amount of concentrate diet contain 3% of cumin seeds. All animals were grazed daily for 3-4 hours as one group. The third and the fourth groups were vasectomized by close vasectomy operation at the beginning of the experiment.  The results revealed that cumin seeds used as feed additives for Awassi ram lambs caused significant (P<0.05) increase in live animal body weight, fasting and empty body weight, hot and cold carcass weights also it had an effect on carcass measurements, empty digestive and stomach weight, most carcass joints weight, rib eye muscle area, Longismus dorsi weight, lean and fat weight in the rack joint compare with the control group. However vasectomy had significant (P<0.05) increase in the body weight, fasting, empty and hot and cold carcass weight, the weight of pelt, full and empty digestive system, most of joint weights, fat tail, fat weight of the rack joint, while the 4th group showed higher values than the most carcass traits compared with the 2nd and 3rd groups and significantly (P<0.05) higher than the control group (1st group). It is concluded that vasectomy and cumin seeds have positive effect on lamb performance and carcass traits. Cumin seeds can be used as effective and cheep feed additives. Further studied are required to prove the suitable ratio of cumin seeds addition alongside with castration in other farm animals.

EVALUATION OF ANDROGENIC PROPERTIES OF PROGESTATIONAL COMPOUNDS IN THE RAT BY THE FEMALE FOETAL MASCULINIZATION TEST

1961 ◽  
Vol 38 (1) ◽  
pp. 128-136 ◽  
Author(s):  
H. F. L. Schöler ◽  
A. M. de Wachter
Keyword(s):  
Histological Examination ◽  
Genital Tract ◽  
The Body ◽  
List Type ◽  
Serial Sections ◽  
Pregnant Rats ◽  
Histological Changes

ABSTRACT A study was made of the effect of nine progestational compounds on the genital tract of female foetuses. The progestins were injected subcutaneously into pregnant rats from the 15th to the 21st day. The influence of these compounds was studied on the female foetuses by: I measuring of the ano-genital distance at birth II inspection of the gonads III histological examination of the lower part of the body, the ovaries and the clitoris. It appears that classification of sex by assuming that the ano-genital distance of more than 3 mm is always of the male species is incorrect, as shown by examination of the gonads. Furthermore that new-borns with a normal ano-genital distance and rightly classified as females may show histological changes in the genital tract, indicative of masculinization. It is concluded that the study of the masculinizing effect of progestins should be carried out by inspection of the gonads and serial sections of appropriate organs and tissues.

scholarly journals Differential Diagnosis of Congenital Pneumonia in Newborns with Low and Extremely Low Body Weight (Morphological Study)

2018 ◽  
Vol 14 (4) ◽  
pp. 4-14 ◽  
Author(s):  
S. A. Perepelitsa ◽  
E. F. Smerdova
Keyword(s):  
Body Weight ◽  
Respiratory Failure ◽  
Histological Examination ◽  
Premature Infants ◽  
The Body ◽  
Lung Damage ◽  
Extremely Low Birth Weight ◽  
Postnatal Life ◽  
Perinatal Hypoxia ◽  
Hyaline Membranes

The purpose of the study is a comprehensive assessment of morphological changes in the placenta and lungs to detect early signs of congenital pneumonia in extremely premature infants.Materials and methods. Protocols of post-mortem examinations of 23 preterm newborns died from severe respiratory failure were analyzed. The average gestational age of the newborns was 26.4±2.7 weeks and the body weight at birth was 972.4±355.8 grams. In the sample, 78.3% of infants had an extremely low birth weight (ELBW). At birth, all newborns presented severe asphyxia. Newborn underwent several types of respiratory therapy since birth: Mechanical ventilation was performed in 65.2% of newborns since their birth, non-invasive ventilation was performed in 26.1% of cases, and 8.7% of patients underwent oxygenotherapy through a facial mask. In all cases, there was an unfavorable course of the neonatal period, a progressive deterioration of newborns' condition, and a lethal outcome. A comprehensive histological examination of the placenta and the lungs of deceased premature newborn infants was performed.Results. Congenital infections of different localizations remain the leading cause of death.Congenital pneumonia and generalized infections are clinically manifested at birth by severe perinatal hypoxia and respiratory failure. In the case of congenital pneumonia, the morphological patterns are polymorphic and characterize the severity of lung damage. For some newborns, these patterns include accumulation of exudates and fibrin, segmented leukocytes, fragments of basophilic coccal microflora, and a large number of colony forming bacilli, and desquamated alveolocytes with a deformed nucleus are visualized in the deformed lumen of the alveoli and bronchi. Diffuse lymphoid-leukocyte infiltration in the septa and respiratory parts of the lungs are typical for other infants. Histological examination find lumpy or lamellar eosinophilic hyaline membranes in alveoli in specimens from these newborns. Diffuse, focal or confluent segmentonuclear infiltration in various lung structures is commonly combined with hyaline membranes of various localizations and sizes. Hyaline membranes were detected in 93.5% of cases.Conclusion. Very early preterm delivery is associated with intrauterine pneumonia and systemic infection in extremely premature infants. Early clinical and laboratory signs of intrauterine infectious lung include severe perinatal hypoxia, very low Apgar score and laboratory test findings (hypoxaemia and decompensated metabolic lactate acidosis) that are resistant to standard resuscitation measures. Hypoxemia and decompensated metabolic acidosis persisting during the first hours of postnatal life indicate the severity of intrauterine lung damage and require a rapid change of treatment aimed at normalization of lung function, prevention of complications in the respiratory system, hemostasis and central nervous system. Clinicians should be better informed about the features of early postnatal adaptation of extremely premature infants with congenital pneumonia to provide appropriate treatment.

scholarly journals Study of Histological Changes in the Bones of Front and Hind Limbs of White Rat Treated with Ibuprofen and Lepidium Sativum

2021 ◽  
Vol 11 (2) ◽  
pp. 1988-2003
Author(s):  
Zainab Salah Abdul Jabbar
Keyword(s):  
Body Weight ◽  
Aqueous Extract ◽  
Water Extract ◽  
The Body ◽  
Male Rats ◽  
Lepidium Sativum ◽  
Control Group ◽  
Histological Changes ◽  
Hind Limbs ◽  
Animal House

The current study was conducted to evaluate the morphological and histological changes in the front and hind limbs of Male albino rat belonging to the strain Sprague Dawley, treated with Ibuprofen and the possible protective effects of aqueous extract of Lepidium sativum. The study was performed in the animal house of Department of Biology Collage of Education for Girls University of Kufa. The study lasted seven months from September 2020 until February 2021 by following (80) male rats and were (16-20) weeks that weighted between (200-250)g which was divided in to eight groups each group consist of ten males. The first group was the orally given the normal saline only, and it was control group. The second group was treated orally with Ibuprofen at concentration of (400) mg/kg while the third group was administered Ibuprofen at concentration (400)mg/kg+ aqueous extract of Lepidium sativum seeds with concentration of (50) mg/kg. The fourth group was dosage Ibuprofen at (400)mg/kg+ extract of Lepidium sativum seeds with concentration (100)mg/kg orally too. The fifth group was treated with Ibuprofen at concentration (400)mg/kg +aqueous extract of Lepidium sativum at concentration (150) mg/kg orally. The sixth group was orally given the aqueous extract of Lepidium sativum seeds with concentration (50)mg/kg. The seventh group was treated with the aqueous extract of Lepidium sativum seeds with concentration (100)mg/kg orally. The last group was submitted to the aqueous extract of Lepidium sativum seeds with concentration (150)mg/kg by oral all groups were conducted once day from the first day until the sacrifice which was in two stages on (30 and 45)days. The current study included the process of recording the animal weights of body before and after the completion of experiment as well as weights of bones for front and hind limbs after the end of dose period The study included the histolgical sections of the limbs bones. It was absorved through the macroscopic examination of males dosed with Ibuprofen drug at concentration (400)mg/kg lack of movement and ,anorexia and sluggishness during a period 45 days. The results of statistical analysis showed significant decrease (P<0.05) in the body weight and the weight of limbs bones and the in treatment that were treated with Ibuprofen (30) and (45) days compared with control group. The results also showed decreased significant differences in body weight and weight of limbs in the groups were treated with Ibuprofen + water extract of lepidum sativum seeds (50)mg/kg also the result showed decrease (p<0.05) in body weight in the group of Ibuprofen + water extract of lepidum sativum seeds at (100)mg/kg in, the first dose 30 days, while there was no significant in the same group for the second dose(45) days. As for the group that was dose orally the aqueous extract of Lepidium Sativum seeds (50,100,150) mg/kg and for first and second dose showed significant increase ()in wight body and bones limb but no significant in length body and length of bones. Also patholgical changes were observed in the histolgical section of bone that dosed ibuprofen such as cellular changes in osteocytes, the lacuna looked empty without osteocyt and effected of cell components and cell life. The ather histolgical change was show in the bone marrow that decrease in blood cells components with hypoplasia and replacement of heamatopia with adipose content in the marrow cavity. There was no histopatholgical changes in the groups that treated with Ibuprofen +water extract of lipdium sativum seeds (50,100,150)Mg/kg compared with control group. As well as the group that was treated with water extract of Lepidium sativum showed cellular activity. From this study, it was concluded that Ibuprofen drug has toxic effects in the osteocytes that was affected in the bone tissue and bone formation for long term while the concentration aqueous extract of Lepidium sativum seeds has prevented the uncertain effects of drug. This stuy showed the important role of lepidum sativum as food supplements rich with vitamins and minerals on growth of bones.

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