scholarly journals 經絡現象研究的沉寂與出新

1998 ◽  
Vol 1 (2) ◽  
pp. 101-114
Author(s):  
Chengzhong LIU
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Modern Medicine ◽  
Physical Basis ◽  
Clinical Neurology ◽  
Anatomical Structures ◽  
Research Orientation ◽  
Digital Commons ◽  
Patient Will ◽  
Tremendous Amount

LANGUAGE NOTE | Document text in Chinese; abstract also in English.經絡現象主要指循經感傳。它的表現形式是當向人體上施加一點刺激時，其所產生的定位覺會緩慢地移動走行，或者走行到軀體的病灶 處，或者走行到頭頂。它的走行軌跡呈現為特殊的分佈形式，在中華醫學中被稱為經絡。從現代醫學的角度來看，循經感傳的科學稱呼應該是移動性定位覺或知覺延伸。這是一個很常見但卻不被人們所認識的高等臨床神經學現象。多年來，誤認為循經感傳的軌跡是一個有結構的管道，曾經投入大量的人力與財力企圖找到它的實物或物質基礎，但卻是遠遠失敗，使中國的經絡現象研究陷入沉寂。《臨床經絡現象學》與《高等臨床神經學》兩本書的出版；季鍾樸學術思想的成熟與彰明；以經絡現象為研究對象與「透過現象看本質」的正確路線的被承認；經絡研究新一輪五年計劃的啟動。中國的經絡現象研究正在走向出新。Channel-phenomenon (or jingluo phenomenon, in Chinese) is a special sensational phenomenon discovered by traditional Chinese medicine over two thousand years ago. When stimulating certain points on a patient's skin, the patient will have a sensation moving along specifiable routes, terminating at the location of disease or the top of the head. With a definite distribution pattern on the human body, such specifiable routes are named jingluo by traditional Chinese medicine and constitute the theoretical and practical basis for the treatment of acupuncture. In modern medicine, this propagated sensation along channels can be called "moving topesthesia", or "perceptual extension."For many years researchers on channel-phenomenon had concentrated their efforts on attempting to discover a concrete tubing structure below the specified routes. They wanted to find an observable anatomical structure or particular physical basis so as to ground the channel-phenomenon on a solid basis. According to their understanding, the essence of channel-phenomenon had to lie in particular anatomical tubes as a physical basis. Without such a physical basis, the channel-phenomenon could not have real objective existence. However, although tremendous amount of labor and energy were invested in the hope of finding particular anatomical tubes for channels, it was done in vain. Consequently, Chinese intellectual research on channel-phenomenon came to silence.However, it is mistaken to believe that the essence of channel-phenomenon has to lie in a particular physical basis. The propagated sensation along channels as a phenomenon has been there for thousands of years and continue to be confirmed by patients in the present time. Why must research on channel-phenomenon be separated from patients’ vivid experiences and instead be focused only on looking for special anatomical structures? On reflection, it happened that some had held a very narrow-minded and simplified notion of objectivity. Indeed, objectivity does not always require a particular physical basis. Patients’ experiences and feelings are equally objective facts for intellectual research.Fortunately, as we can learn from the lessons and experiences we had in the past, we will readjust our research orientation. With the recent publication of the two new books about higher clinical neurology in the field, it looks that the research on channel-phenomenon will encounter its renaissance.DOWNLOAD HISTORY | This article has been downloaded 38 times in Digital Commons before migrating into this platform.

Opening up a New Field of Modern Medical Research 1

2020 ◽  
Author(s):  
Xiaoguang Li
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Human Body ◽  
Low Cost ◽  
Acupuncture Point ◽  
Modern Medicine ◽  
Body Structure ◽  
Special Effect ◽  
Special Knowledge ◽  
Opening Up

Modern medicine tells us that the human body is an organism composed of heart, lung, liver, kidney, spleen, stomach, brain, nerves, muscles, bones, blood vessels, blood and so on, while traditional Chinese medicine believes that besides these tissues and organs, the human body still has another part of the structure, traditional Chinese medicine calls them Jing Luo and Shu Xue. Jing Luo means the longitudinal line of the human body and the accompanying net, translated into English Meridians and Collaterals. Shu Xue means holes distributed on Jing Luo and outside Jing Luo, because stimulating Shu Xue's position by acupuncture, massage and other methods can cure diseases, so Shu Xue is translated into English acupuncture point, abbreviated as acupoint or point. Meridians and acupoints are the special knowledge of human body structure in traditional Chinese medicine. Traditional Chinese medicine not only draws the distribution map of the meridians and acupoints in the human body, but also has been using them to treat diseases for thousands of years. There are hundreds of these acupoints, stimulating each one by acupuncture, massage or other methods will have a special effect on the human body and can treat various diseases. But what effect does stimulating every acupoint have on the human body so that it can treat various diseases? The discussion of traditional Chinese medicine is vague and incomprehensible, and can not be proved by experiments. According to the author's research for more than 30 years, this paper makes a clear and accurate exposition of the effects on the human body and diseases that can be treated with acupoint massage. These statements can be proved by experiments, so they are believed to be reliable. It is hoped that meridians, acupoints and massage therapy can be incorporated into modern medicine and become a part of modern medicine after being proved by others through experiments. Massaging acupoints can not only treat many diseases that are difficult to be treated with drugs, but also have simple methods and low cost.

1+1 > 2: Integration of the Host-directed Traditional Chinese Medicine and the Virus-targeted Modern Medicine in Control of COVID-19

2020 ◽  
Vol 7 (2) ◽  
pp. 89-94
Author(s):  
Jianjun Sun
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Infectious Diseases ◽  
Modern Medicine ◽  
The World ◽  
Plausible Mechanism

The COVID-19 pandemic has caused millions of infections and hundreds of thousands deaths in the world. The pandemic is still ongoing and no specific antivirals have been found to control COVID-19. The integration of Traditional Chinese Medicine with supportive measures of Modern Medicine has reportedly played an important role in the control of COVID-19 in China. This review summarizes the evidence of TCM in the treatment of COVID-19 and discusses the plausible mechanism of TCM in control of COVID-19 and other viral infectious diseases.

Systems Biology Technologies Enable Personalized Traditional Chinese Medicine: A Systematic Review

2012 ◽  
Vol 40 (06) ◽  
pp. 1109-1122 ◽  
Author(s):  
Xijun Wang ◽  
Aihua Zhang ◽  
Hui Sun ◽  
Ping Wang
Keyword(s):  
Systems Biology ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Disease Diagnosis ◽  
Modern Medicine ◽  
Therapeutic Approaches ◽  
Current Trends ◽  
Close Relationship ◽  
The Right ◽  
Personalize Medicine

Traditional Chinese medicine (TCM), an alternative medicine, focuses on the treatment of human disease via the integrity of the close relationship between body and syndrome analysis. It remains a form of primary care in most Asian countries and its characteristics showcase the great advantages of personalized medicine. Although this approach to disease diagnosis, prognosis and treatment has served the medical establishment well for thousands of years, it has serious shortcomings in the era of modern medicine that stem from its reliance on reductionist principles of experimentation and analysis. In this way, systems biology offers the potential to personalize medicine, facilitating the provision of the right care to the right patient at the right time. We expect that systems biology will have a major impact on future personalized therapeutic approaches which herald the future of medicine. Here we summarize current trends and critically review the potential limitations and future prospects of such treatments. Some characteristic examples are presented to highlight the application of this groundbreaking platform to personalized TCM as well as some of the necessary milestones for moving systems biology of a state-of-the-art nature into mainstream health care.

scholarly journals Xiaojin Pill with natural musk in the treatment of plasma cell mastitis

2021 ◽  
Vol 6 (3) ◽  
Keyword(s):  
Surgical Treatment ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Plasma Cell ◽  
Plasma Cells ◽  
Modern Medicine ◽  
Breast Diseases ◽  
Benign Breast Diseases

Introduction: Plasma cell mastitis is a rare benign suppurative disease of the breast based on the dilatation of mammary ducts and infiltration of plasma cells. Modern medicine focuses on surgical treatment. It is easy to recur after operation. Xiaojin Pill with natural musk is a oral traditional Chinese medicine and plays a role in benign breast diseases. There are very few reports on the use of Xiaojin Pill with natural musk in treating plasma cell mastitis yet. Cases: This paper reports 3 cases of plasma cell mastitis who received Xiaojin Pill with natural musk treatment. Patients were successfully treated after accepting Xiaojin Pill with natural musk for several weeks.

scholarly journals Smart Responsive Nanoformulation for Targeted Delivery of Active Compounds From Traditional Chinese Medicine

2020 ◽  
Vol 8 ◽  
Author(s):  
Xuejun Jiang ◽  
Mei Lin ◽  
Jianwen Huang ◽  
Mulan Mo ◽  
Houhe Liu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Targeted Delivery ◽  
Drug Delivery Systems ◽  
Redox Status ◽  
Modern Medicine ◽  
Active Compounds ◽  
Stimulus Responsive ◽  
Internal Stimulus ◽  
Targeted Release

Traditional Chinese medicine (TCM) has been used to treat disorders in China for ~1,000 years. Growing evidence has shown that the active ingredients from TCM have antibacterial, antiproliferative, antioxidant, and apoptosis-inducing features. However, poor solubility and low bioavailability limit clinical application of active compounds from TCM. “Nanoformulations” (NFs) are novel and advanced drug-delivery systems. They show promise for improving the solubility and bioavailability of drugs. In particular, “smart responsive NFs” can respond to the special external and internal stimuli in targeted sites to release loaded drugs, which enables them to control the release of drug within target tissues. Recent studies have demonstrated that smart responsive NFs can achieve targeted release of active compounds from TCM at disease sites to increase their concentrations in diseased tissues and reduce the number of adverse effects. Here, we review “internal stimulus–responsive NFs” (based on pH and redox status) and “external stimulus–responsive NFs” (based on light and magnetic fields) and focus on their application for active compounds from TCM against tumors and infectious diseases, to further boost the development of TCM in modern medicine.

scholarly journals Navigating Traditional Chinese Medicine Network Pharmacology and Computational Tools

2013 ◽  
Vol 2013 ◽  
pp. 1-23 ◽  
Author(s):  
Ming Yang ◽  
Jia-Lei Chen ◽  
Li-Wen Xu ◽  
Guang Ji
Keyword(s):  
Systems Biology ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Network Models ◽  
Research Process ◽  
Modern Medicine ◽  
Machine Learning Algorithms ◽  
Network Pharmacology ◽  
Research Approach ◽  
Computational Tools

The concept of “network target” has ushered in a new era in the field of traditional Chinese medicine (TCM). As a new research approach, network pharmacology is based on the analysis of network models and systems biology. Taking advantage of advancements in systems biology, a high degree of integration data analysis strategy and interpretable visualization provides deeper insights into the underlying mechanisms of TCM theories, including the principles of herb combination, biological foundations of herb or herbal formulae action, and molecular basis of TCM syndromes. In this study, we review several recent developments in TCM network pharmacology research and discuss their potential for bridging the gap between traditional and modern medicine. We briefly summarize the two main functional applications of TCM network models: understanding/uncovering and predicting/discovering. In particular, we focus on how TCM network pharmacology research is conducted and highlight different computational tools, such as network-based and machine learning algorithms, and sources that have been proposed and applied to the different steps involved in the research process. To make network pharmacology research commonplace, some basic network definitions and analysis methods are presented.

scholarly journals Model Organisms and Traditional Chinese Medicine Syndrome Models

2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
Shuang Ling ◽  
Jin-Wen Xu
Keyword(s):  
Animal Model ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Evaluation System ◽  
Pharmacological Action ◽  
Modern Medicine ◽  
Model Organisms ◽  
Traditional Chinese Medicine Syndrome ◽  
The Difference ◽  
Tcm Syndrome

Traditional Chinese medicine (TCM) is an ancient medical system with a unique cultural background. Nowadays, more and more Western countries due to its therapeutic efficacy are accepting it. However, safety and clear pharmacological action mechanisms of TCM are still uncertain. Due to the potential application of TCM in healthcare, it is necessary to construct a scientific evaluation system with TCM characteristics and benchmark the difference from the standard of Western medicine. Model organisms have played an important role in the understanding of basic biological processes. It is easier to be studied in certain research aspects and to obtain the information of other species. Despite the controversy over suitable syndrome animal model under TCM theoretical guide, it is unquestionable that many model organisms should be used in the studies of TCM modernization, which will bring modern scientific standards into mysterious ancient Chinese medicine. In this review, we aim to summarize the utilization of model organisms in the construction of TCM syndrome model and highlight the relevance of modern medicine with TCM syndrome animal model. It will serve as the foundation for further research of model organisms and for its application in TCM syndrome model.

scholarly journals Management of Hepatic Encephalopathy by Traditional Chinese Medicine

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Chun Yao ◽  
Nong Tang ◽  
Guoxiang Xie ◽  
Xiaojiao Zheng ◽  
Ping Liu ◽  
...  
Keyword(s):  
Nervous System ◽  
Hepatic Encephalopathy ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Liver Dysfunction ◽  
Clinical Manifestations ◽  
Modern Medicine ◽  
Future Perspective ◽  
Therapeutic Approaches ◽  
Complex Mechanisms

In spite of the impressive progress in the investigation of hepatic encephalopathy (HE), the complex mechanisms underlying the onset and deterioration of HE are still not fully understood. Currently, none of the existing theories provide conclusive explanations on the symptoms that link liver dysfunction to nervous system disorders and clinical manifestations. This paper summarized the diagnostic and therapeutic approaches used for HE in modern medicine and traditional Chinese medicine and provided future perspective in HE therapies from the viewpoint of holistic and personalized Chinese medicine.

scholarly journals Systems Pharmacology Dissection of Traditional Chinese Medicine Wen-Dan Decoction for Treatment of Cardiovascular Diseases

2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Tao-Hua Lan ◽  
Lu-Lu Zhang ◽  
Yong-Hua Wang ◽  
Huan-Lin Wu ◽  
Dan-Ping Xu
Keyword(s):  
Chinese Medicine ◽  
Cardiovascular Diseases ◽  
Traditional Chinese Medicine ◽  
Molecular Mechanisms ◽  
Modern Medicine ◽  
System Level ◽  
Therapeutic Effects ◽  
Active Compounds ◽  
System Pharmacology ◽  
Underlying Mechanisms

Cardiovascular diseases (CVDs) have been recognized as first killer of human health. The underlying mechanisms of CVDs are extremely complicated and not fully revealed, leading to a challenge for CVDs treatment in modern medicine. Traditional Chinese medicine (TCM) characterized by multiple compounds and targets has shown its marked effects on CVDs therapy. However, system-level understanding of the molecular mechanisms is still ambiguous. In this study, a system pharmacology approach was developed to reveal the underlying molecular mechanisms of a clinically effective herb formula (Wen-Dan Decoction) in treating CVDs. 127 potential active compounds and their corresponding 283 direct targets were identified in Wen-Dan Decoction. The networks among active compounds, targets, and diseases were built to reveal the pharmacological mechanisms of Wen-Dan Decoction. A “CVDs pathway” consisted of several regulatory modules participating in therapeutic effects of Wen-Dan Decoction in CVDs. All the data demonstrates that Wen-Dan Decoction has multiscale beneficial activity in CVDs treatment, which provides a new way for uncovering the molecular mechanisms and new evidence for clinical application of Wen-Dan Decoction in cardiovascular disease.

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