scholarly journals Süt ve Süt Ürünlerinde Bulunan Biyoaktif Peptitler, Antimikrobiyal Özellikleri ve İnsan Sağlığı Üzerindeki Etkileri

2020 ◽  
Vol 8 (1) ◽  
pp. 158
Author(s):  
Selda Bulca ◽  
Burcu Güvenç
Keyword(s):  
Human Health ◽  
Bioactive Peptides ◽  
Proteolytic Enzymes ◽  
Antimicrobial Properties ◽  
Milk Proteins ◽  
Nutritional Values ◽  
Physiological Properties ◽  
Mineral Binding ◽  
Hydrolysis Of ◽  
Positive Effect

In recent years, apart from the nutritional values of foods, functional properties have also gained importance. Bioactive peptides are the fragmentation products of proteins that have a positive effect on human health. Bioactive peptides in cow's milk are released as a result of hydrolysis of milk proteins with proteolytic enzymes. Bioactive peptides have biochemical and physiological properties such as immune regulation, mineral binding, antimicrobial, antihypertensive, opioid, anti-oxidative, anti-ulcerative, antithrombotic, antitumor and apoptosis. In this review, bioactive peptides in milk and milk products and their antimicrobial properties and effects on human health were evaluated.

Biofunctional properties of milk protein derived bioactive peptides -A review

2015 ◽  
Vol 34 (4) ◽  
Author(s):  
Prasad Patil ◽  
Akanksha Wadehra ◽  
Varsha Garg ◽  
Kanchan Munjal ◽  
Sudhir Kumar Tomar ◽  
...  
Keyword(s):  
Milk Protein ◽  
Bioactive Peptides ◽  
Therapeutic Potential ◽  
Proteolytic Enzymes ◽  
Biological Activities ◽  
Milk Proteins ◽  
Physiological Effect ◽  
Amino Acid Sequences ◽  
The Body ◽  
Biologically Active

Milk has long been acknowledged as a source of macro- and micro nutrients. Presently, several identified biologically active substances from milk and their derivatives has attracted much attention from the scientific community. These bioactive compounds confer many health benefits that might support disease prevention. Worldwide, there is an increasing interest in the therapeutic potential of bioactive peptides which collectively present a cornucopia of bioactivities for utilization in humans. Bioactive peptides are hydrolysates with specific amino acid sequences that exert a positive physiological effect on the body. Most of the biological activities are encrypted within the primary sequence of the native protein and can be released during digestion by proteolytic enzymes in the gastrointestinal tract or during fermentation and food processing. Milk protein is an important source of bioactive peptides which may contribute to regulate the nervous, gastrointestinal, and cardiovascular systems as well as the immune system. Milk protein derived bioactive peptides are shown to have antihypertensive, antimicrobial, immunomodulatory, antioxidative and mineral-binding properties. Bioactive peptides derived from milk proteins are of particular interest to the food industry due to the potential functional and physiological roles that they exhibit.

Bioactive Proteins and Peptides in Foods

2011 ◽  
Vol 81 (23) ◽  
pp. 181-192 ◽  
Author(s):  
Barbara Walther ◽  
Robert Sieber
Keyword(s):  
Gastrointestinal Tract ◽  
Bioactive Peptides ◽  
Proteolytic Enzymes ◽  
Biological Activities ◽  
Health Claims ◽  
Biological Functions ◽  
Food Proteins ◽  
Bioactive Proteins ◽  
Mineral Binding ◽  
Proteins And Peptides

Increasing amounts of data demonstrate a bioactive role of proteins and peptides above and beyond their nutritional impact. The focus of the investigations has mainly been on vitamin- and mineral-binding proteins, on antimicrobial, immunosuppressing/-modulatory proteins, and on proteins with enzyme inhibitory activity as well as on hormones and growth factors from different food proteins; most research has been performed on milk proteins. Because of their molecular size, intact absorption of proteins in the human gastrointestinal tract is limited. Therefore, most of the proteins with biological functions show physiological activity in the gastrointestinal tract by enhancing nutrient absorption, inhibiting enzymes, and modulating the immune system to defend against pathogens. Peptides are released during fermentation or digestion from food proteins by proteolytic enzymes; such peptides have been found mainly in milk. Some of these released peptides exert biological activities such as opiate-like, antihypertensive, mineral-binding, antioxidative, antimicrobial, immuno-, and cytomodulating activity. Intact absorption of these smaller peptides is more likely than that of the larger proteins. Consequently, other organs than the gastrointestinal tract are possible targets for their biological functions. Bioactive proteins as well as bioactive peptides are part of a balanced diet. It is possible to accumulate bioactive peptides in food, for example by using specific microorganisms in fermented dairy products. Although bioactive peptides have been the subject of several studies in vitro and in vivo, their health potential is still under investigation. Up to now, the Commission of European Communities has not (yet) authorized any health claims for bioactive proteins and peptides from food.

scholarly journals Bioactive peptides from milk: animal determinants and their implications in human health

2019 ◽  
Vol 86 (2) ◽  
pp. 136-144 ◽  
Author(s):  
Einar Vargas-Bello-Pérez ◽  
Roberto I. Márquez-Hernández ◽  
Lorenzo E. Hernández-Castellano
Keyword(s):  
Human Health ◽  
Bioactive Peptides ◽  
Bovine Milk ◽  
Milk Proteins ◽  
Heat Stability ◽  
Animal Nutrition ◽  
Beneficial Effects ◽  
Wide Range ◽  
Health Promoting

AbstractMilk is an important protein source in human diets, providing around 32 g protein/l (for bovine milk, which constitutes some 85% of global consumption). The most abundant milk proteins are α-lactalbumin, β-lactoglobulin, αs-casein, β-casein, and κ-casein. Besides their nutritional value, milk proteins play a crucial role in the processing properties of milk, such as solubility, water bonding, heat stability, renneting and foaming, among others. In addition, and most importantly for this review, these proteins are the main source of bioactive components in milk. Due to the wide range of proposed beneficial effects on human health, milk proteins are considered as potential ingredients for the production of health-promoting functional foods. However, most of the evidence for bioactive effects comes from in vitro studies, and there is a need for further research to fully evaluate the true potential of milk-derived bioactive factors. Animal genetics and animal nutrition play an important role in the relative proportions of milk proteins and could be used to manipulate the concentration of specific bioactive peptides in milk from ruminants. Unfortunately, only a few studies in the literature have focused on changes in milk bioactive peptides associated to animal genetics and animal nutrition. The knowledge described in the present review may set the basis for further research and for the development of new dairy products with healthy and beneficial properties for humans.

scholarly journals Potential Relevance of Bioactive Peptides in Sports Nutrition

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3997
Author(s):  
Daniel König ◽  
Jan Kohl ◽  
Simon Jerger ◽  
Christoph Centner
Keyword(s):  
Bioactive Peptides ◽  
Positive Impact ◽  
Proteolytic Enzymes ◽  
Sports Nutrition ◽  
Biologically Active ◽  
Rehabilitation Process ◽  
Practical Applications ◽  
Active Peptides ◽  
Health Related ◽  
Positive Effect

Bioactive peptides are physiologically active peptides mostly derived from proteins following gastrointestinal digestion, fermentation or hydrolysis by proteolytic enzymes. It has been shown that bioactive peptides can be resorbed in their intact form and have repeatedly been shown to have a positive effect on health-related parameters such as hypertension, dyslipoproteinemia, inflammation and oxidative stress. In recent years, there has been increasing evidence that biologically active peptides could also play an important role in sports nutrition. Current studies have shown that bioactive peptides could have a positive impact on changes in body composition and muscular performance, reduce muscle damage following exercise and induce beneficial adaptions within the connective tissue. In the following overview, potential mechanisms as well as possible limitations regarding the sports-related effect of bioactive peptides and their potential mechanisms are presented and discussed. In addition, practical applications will be discussed on how bioactive peptides can be integrated into a nutritional approach in sports to enhance athletic performance as well as prevent injuries and improve the rehabilitation process.

Can be marine bioactive peptides (MBAs) lead the future of foodomics for human health?

2021 ◽  
pp. 1-79
Author(s):  
Abdur Rauf ◽  
Anees Ahmed Khalil ◽  
Muneeb Khan ◽  
Sirajudheen Anwar ◽  
Abdulwahab Alamri ◽  
...  
Keyword(s):  
Human Health ◽  
Bioactive Peptides ◽  
The Future

scholarly journals Role of Proteins and of Some Bioactive Peptides on the Nutritional Quality of Donkey Milk and Their Impact on Human Health

Beverages ◽  
2017 ◽  
Vol 3 (4) ◽  
pp. 34 ◽  
Author(s):  
Silvia Vincenzetti ◽  
Stefania Pucciarelli ◽  
Valeria Polzonetti ◽  
Paolo Polidori
Keyword(s):  
Human Health ◽  
Nutritional Quality ◽  
Bioactive Peptides ◽  
Donkey Milk

scholarly journals The nutritional use of millet grain for food and feed: a review

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Z. M. Hassan ◽  
N. A. Sebola ◽  
M. Mabelebele
Keyword(s):  
Phenolic Compounds ◽  
Human Health ◽  
Pearl Millet ◽  
Egg Production ◽  
Positive Impact ◽  
The Body ◽  
Broiler Performance ◽  
Food And Feed ◽  
High Antioxidant Activity ◽  
Positive Effect

AbstractWorldwide, millets are regarded as a significant grain, however, they are the least exploited. Millet grain is abundant in nutrients and health-beneficial phenolic compounds, making it suitable as food and feed. The diverse content of nutrients and phenolic compounds present in finger and pearl millet are good indicators that the variety of millet available is important when selecting it for use as food or feed. The phenolic properties found in millets compromise phenolic acids, flavonoids, and tannins, which are beneficial to human health. Moreover, finger millet has an exceptionally unique, more abundant, and diverse phenolic profile compared to pearl millet. Research has shown that millet phenolic properties have high antioxidant activity. The presence of phytochemicals in millet grains has positive effect on human health by lowering the cholesterol and phytates in the body. The frantic demands on maize and its uses in multiple industries have merited the search for alternative grains, to ease the pressure. Substitution of maize with pearl and finger millets in the diets of different animals resulted in positive impact on the performance. Including these grains in the diet may improve health and decrease the risks of diseases. Pearl millet of 50% or more can be used in broiler diets without adversely affecting broiler performance or egg production. Of late, millet grain has been incorporated in other foods and used to make traditional beverages. Thus, the core aim of this review is to provide insight and comprehension about the nutritional and phenolic status of millets and their impact on human and livestock.

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