scholarly journals Determination of simethicone in different drug formulations by gravimetry and comparison with the FTIR method

2020 ◽  
Vol 14 (2) ◽  
pp. 153-159
Author(s):  
Muge Guleli ◽  
Sezin İşsev ◽  
Cem Caliskan ◽  
Mahmut Ozbek
Keyword(s):  
Fourier Transform ◽  
Gastrointestinal Tract ◽  
Ftir Spectroscopy ◽  
Gravimetric Method ◽  
T Test ◽  
Test Results ◽  
Drug Formulations ◽  
Significant Difference ◽  
Quantification Analysis

Fourier transform infrared (FTIR) spectroscopy was mostly used in both pharmacopeia and literature studies to determine the assay of simethicone (SMT) in pharmaceuticals. It should be noted that HPLC is used less frequently. As an alternative to the mentioned methods a new, simple, fast, easy-to-apply and very cheap gravimetric method was developed and validated according to ICH guidance entitled Q2B Validation of Analytical Procedures: Methodology for the quantification analysis of simethicone in different pharmaceutical forms. For the simethicone suspension product provided to alleviate too much gas in the gastrointestinal tract, the simethicone amount was determined both by the validated gravimetric method and by the FTIR method defined in the USP and BP monographs, and the results were within the acceptance criteria. It is emphasized that there is no significant difference between the results of gravimetric and FTIR methods according to the calculated F- and t-test results.

scholarly journals ANALISIS KOMPARATIF PENDAPATAN USAHATANI KENTANG VARIETAS SUPERJOHN DAN VARIETAS GRANOLA L DI DESA PINASUNGKULAN UTARA KECAMATAN MODOINDING

2018 ◽  
Vol 14 (1) ◽  
pp. 125
Author(s):  
Neni ., Nuraeni ◽  
Rine ., Kaunang ◽  
Lorraine W. Th. Sondak
Keyword(s):  
Simple Random Sampling ◽  
Potato Production ◽  
T Test ◽  
Farm Income ◽  
P Value ◽  
Test Results ◽  
Average Income ◽  
Two Samples ◽  
Significant Difference

The objective of this research is to know the comparison of Superjohn varieties and varieties of Granola L in Pinasungkulan Utara Village, Modoinding District. The location of the study was determined purposively (purposive sampling), the determination of the number of samples taken by census (Saturated Sampling) for farmers varieties Granola L as much as 20 farmers and 20 farmers Superjohn varieties taken simple random (Simple Random Sampling). The method of analysis used in this research is the analysis of farm income and komaparatif analysis by using t-test two samples Independent Sample T-test. The results showed that the average income of farmers Superjohn varieties is Rp.70.062.947,00 lower than the average income obtained by farmers varieties Granola L Rp.87.029.058,00. It can be seen that the average income difference between the two varieties is Rp.16.960.111,00. Based on statistical test results with MINITAB Program, the calculation of income per hectare obtained significant value of P-Value of 0.01 at α 5% that is 0,01 < 0,05. This means that H0 is rejected and H1 is tested for the fact that there is a significant difference between Superjohn varieties potato production income and Granola L varieties.

scholarly journals Determination of Gossypol in Hamid and Bt (Seeni 1) Cottonseed Oil using Fourier Transform Infrared Spectroscopy

2020 ◽  
Vol 3 (4) ◽  
pp. 227-234
Author(s):  
Samah AM Abdelrahman ◽  
Atif AA Yassin ◽  
Mohamed Elwathig Saeed Mirghani ◽  
Nabil HH Bashir
Keyword(s):  
Fourier Transform ◽  
Ftir Spectroscopy ◽  
Fourier Transform Infrared ◽  
Cottonseed Oil ◽  
Gossypol Content ◽  
Calibration Models ◽  
Significant Difference ◽  
Validation Technique ◽  
Crude Cottonseed Oil

This study was conducted to determine the gossypol content in Bt cottonseed (Seeni-1) oil by using Fourier Transform Infrared (FTIR) spectroscopy with an Attenuated Total Reflectance (ATR) element. The wavelengths used were selected by spiking refined, bleached deodorized palm oil (RBDPO) to gossypol concentrations of 0-5% and noting the regions of maximal absorbance. Absorbance values of the wavelength regions 3700-2400 & 1900-750 cm-1 and a partial least squares (PLS) method were used to derive calibration models for Hamid cottonseed oil, Seeni-1 cottonseed oil, and gossypol-spiked RBDPO. The coefficients of determination (R2) for the calibration models were computed for the FTIR spectroscopy results against those found by using the wet chemical method AOCS method Ba 8�78. The R2 was 0.8916, 0.9581, and 0.9374 for Hamid cottonseed oil, Seeni-1 cottonseed oil, and gossypol-spiked RBDPO, respectively. The standard error (SE) of the calibration was 0.053, 0.078, and 0.062, respectively. The calibration models were validated using the cross-validation technique within the same set of oil samples. The results of FTIR spectroscopy as a useful technique determining gossypol content in crude cottonseed oil showed that there is a significant difference (p <0.05) in the amount of gossypol content in Hamid and Bt Seeni-1 cottonseed oils.

scholarly journals Elements of Opportunity and Poultry Farms Performance in Delta State, Nigeria

2015 ◽  
Vol 4 (4) ◽  
pp. 102
Author(s):  
Rodney A. Isiorhovoja
Keyword(s):  
Urban Areas ◽  
Formal Education ◽  
Prior Experience ◽  
T Test ◽  
Test Results ◽  
Gross Margin ◽  
Rural And Urban Areas ◽  
Rural And Urban ◽  
Significant Difference ◽  
Poultry Farmers

The paper examines the existence, if any, of differences in gross margin between rural and urban areas in Delta State, Nigeria. Data were collected from all 275 poultry farmers registered with the Delta State Ministry of Agriculture, Livestock Department. The null hypotheses was that there is no significant difference in poultry farm gross margin between locations in terms rural and urban areas; managers with formal education in agriculture and managers who have no formal education in agriculture; and managers who have and who do not have prior experience in poultry business. Data were collected from all 275 poultry farmers registered with the State Ministry Agriculture using copies of a structured questionnaire and were analyzed using frequency counts, means and T-test. Amongst the findings were: Majority of poultry business operators have low level formal education in disciplines not related to agriculture; there was a significant difference in the mean number of years of schooling and courses studied between rural and urban areas but that there was no significant difference in number of years of prior experience. The T-test results failed to reject the three null hypotheses. The study concluded that indeed elements of opportunity may vary from place to place but the ability to exploit the benefits may moderate or accentuate performance. Entrepreneurial capacity building was recommended for poultry business operators’ state wide.

scholarly journals A Comparative Study of Mental Health among Old People

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Vandana N Solanki
Keyword(s):  
Mental Health ◽  
Comparative Study ◽  
Old Age ◽  
T Test ◽  
Test Results ◽  
Old People ◽  
Significant Difference ◽  
And Gender

The study was intended to examine the effect of mental health on old people. Aim: The aim was to estimate the prevalence of mental health in old people and to determine the association of mental health with types of family and gender. Sample: The sample consists of 120 old people from different old age home and family in Rajkot district area. The sample was selected from randomly. Design: 2*2research design was used the present study. Tools: Mental Health was measured through a questionnaire ‘Mental Health Inventory’was used. Test developed by Bhatt D & Gida G. in (1992).The data was analyzed by the t test. Results: There will be no significant difference between Gender and Types of Area in relation to their mental health. Conclusions: Our study demonstrates a higher prevalence of mental health in old people.

scholarly journals Analisis Perbandingan Kinerja Keuangan Dan Ekonomi Sosial Bank Syariah Antara Sebelum Dan Sesudah Ditetapkannya Fatwa MUI Tentang Haramnya Bunga Bank

2017 ◽  
Vol 3 (12) ◽  
pp. 973
Author(s):  
Lia Auliah Rachmah ◽  
Nisful Laila
Keyword(s):  
Social Performance ◽  
Secondary Data ◽  
T Test ◽  
Quantitative Approach ◽  
Islamic Banks ◽  
Financial Reports ◽  
Significant Difference ◽  
Before And After

This study aims to find out the comparison between the performance of Islamic Banks including financial performances such as the ratio of ROA, ROE, FDR and CAR as wells economic and social performance such as MMR ratio before and after the determination of fatwa regarding the prohibition against bank interest. Quantitative approach and independent sample t-test has been used in this study. The data is a secondary data which was obtained by collecting the annual financial reports. The result of the independent sample t-test shows that there are significant differences between the performance of the Islamic banks before and after the fatwa on the ratio of ROE, FDR and MMR. Whereas on the ratio of ROA and CAR have no significant difference before and after the fatwa.

scholarly journals A Comparative Study of Anxiety among Diabetic Patients

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Vandana N Solanki
Keyword(s):  
Comparative Study ◽  
Research Design ◽  
T Test ◽  
Diabetic Patients ◽  
Test Results ◽  
Anxiety Test ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
And Gender

The study was intended to examine the effect of Anxiety on diabetic patients. Aim: The aim was to estimate the prevalence of anxiety in patients with diabetes and to determine the association of anxiety with area and gender. Sample: The sample consists of 160 diabetic patients from different hospital in Rajkot district area. The sample was selected from randomly. Design: 2*2 research design was used the present study. Tools: Anxiety was measured through a questionnaire ‘Sinha’s Comprehensive Anxiety Test (SCAT) was used. Test developed by A.K.P Sinha and L.N.K Sinha in (1995).The data was analyzed by the t test. Results: There will be no significant difference between Gender and Types of Area in relation to their Anxiety. Conclusions: Our study demonstrates a higher prevalence of anxiety in diabetic patients. No factor was significantly associated with anxiety.

CuSO4-TiO2 as Kjeldahl Digestion Catalyst in Manual Determination of Crude Protein in Animal Feeds

1986 ◽  
Vol 69 (4) ◽  
pp. 664-666
Author(s):  
Peter F Kane
Keyword(s):  
Standard Deviation ◽  
Crude Protein ◽  
T Test ◽  
Environmental Concerns ◽  
Animal Feeds ◽  
Significant Difference ◽  
Kjeldahl Digestion ◽  
Student’S T ◽  
Student’S T Test

Abstract The official AOAC manual Kjeldahl methods for determining crude protein in animal feeds have several disadvantages. For the HgO catalyst method, there are environmental concerns and a lengthy digestion. For the CuS04 catalyst method, the digestion period is shorter, but still 90 min. A different catalyst combination, CuS04-Ti02, makes 40 min digestion feasible. Comparison of these catalysts on a group of representative feeds resulted in a mean difference, Cu-Ti minus HgO, of 0.034% protein. Standard deviation of the differences was 0.36. A Student’s t-test showed no significant difference. The method will be collaboratively studied.

Sign in / Sign up

Export Citation Format

Share Document