scholarly journals Epidemiología enfermera del duelo en Canarias

2020 ◽  
pp. 27-48
Author(s):  
Martín Rodríguez-Álvaro ◽  
Keyword(s):  
Protective Factors ◽  
Canary Islands ◽  
Significant Loss ◽  
Care Needs ◽  
Diagnostic Labels ◽  
Wide Range ◽  
High Prevalence ◽  
Functional Patterns ◽  
Limited Process

Grief is a natural and self-limited process of adaptation to a new reality that arises after a significant loss, real or perceived, with a wide range of manifestations that produce an impact on the health of the mourner. Objective: To know and identify, broken down by diagnostic gradient, the prevalence of mourning in the Canary Islands, as well as the needs of care before the diagnosis of mourning of the mourners. Results: Significantly, more women than men are identified in the three diagnostic labels under study. Patients with bereavement complications previously presented depression, anxiety, and risk of loneliness. The result of the pattern assessment is paradoxical. Conclusion: Grief is a multidimensional phenomenon that can hardly be assessed from a reductionist tool such as functional patterns. The high prevalence of complications in women’s grief should be studied in-depth, associating it with their previous burdens of care and vulnerability. The association between loneliness and complicated grief is evident, and the role of community nurses in these patients may be essential. Further research is needed on the care needs of bereaved persons, both complicated and uncomplicated, as well as on their predictive and protective factors.

scholarly journals In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii

2021 ◽  
Vol 12 ◽  
Author(s):  
Kelly Conde-Pérez ◽  
Juan C. Vázquez-Ucha ◽  
Laura Álvarez-Fraga ◽  
Lucía Ageitos ◽  
Soraya Rumbo-Feal ◽  
...  
Keyword(s):  
Acinetobacter Baumannii ◽  
Multidrug Resistant ◽  
Significant Loss ◽  
Genetic Redundancy ◽  
Double Mutant Strain ◽  
Wide Range ◽  
Depth Analysis ◽  
High Level ◽  
Antivirulence Agents

Acinetobacter baumannii is a multidrug-resistant pathogen that represents a serious threat to global health. A. baumannii possesses a wide range of virulence factors that contribute to the bacterial pathogenicity. Among them, the siderophore acinetobactin is one of the most important, being essential for the development of the infection. In this study we performed an in-depth analysis of the acinetobactin cluster in the strain A. baumannii ATCC 17978. For this purpose, nineteen individual isogenic mutant strains were generated, and further phenotypical analysis were performed. Individual mutants lacking the biosynthetic genes entA, basG, basC, basD, and basB showed a significant loss in virulence, due to the disruption in the acinetobactin production. Similarly, the gene bauA, coding for the acinetobactin receptor, was also found to be crucial for the bacterial pathogenesis. In addition, the analysis of the ΔbasJ/ΔfbsB double mutant strain demonstrated the high level of genetic redundancy between siderophores where the role of specific genes of the acinetobactin cluster can be fulfilled by their fimsbactin redundant genes. Overall, this study highlights the essential role of entA, basG, basC, basD, basB and bauA in the pathogenicity of A. baumannii and provides potential therapeutic targets for the design of new antivirulence agents against this microorganism.

Immunology of Bipolar Disorder

2018 ◽  
pp. 211-226
Author(s):  
Izabela G. Barbosa ◽  
Moises E. Bauer ◽  
Jair C. Soares ◽  
Antônio L. Teixeira
Keyword(s):  
Bipolar Disorder ◽  
Mononuclear Cells ◽  
Immune Cell ◽  
Course Of Illness ◽  
Wide Range ◽  
High Prevalence ◽  
The Central Nervous System ◽  
Immune Changes ◽  
Inflammatory Changes

Bipolar disorder (BD) is a severe, chronic, and recurrent psychiatric illness. It has been associated with a high prevalence of medical and psychiatric comorbidities, cognitive impairment, and a progressive course of illness. Its neurobiology is not completely understood, but recent evidence has shown a wide range of immune changes. Here we review several data supporting the presence of immunological dysfunction in BD: (1) increased frequency of autoimmune diseases; (2) distinct immune cell profile; (3) altered release of cytokines by stimulated mononuclear cells; (4) elevated levels of circulating immune markers; (5) inflammatory changes in the central nervous system; (6) relationship with clinical comorbidities; and (7) the effect of current treatments on the immune system and the role of immunomodulatory agents.

scholarly journals Is Autism a Member of a Family of Diseases Resulting from Genetic/Cultural Mismatches? Implications for Treatment and Prevention

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Staci D. Bilbo ◽  
John P. Jones ◽  
William Parker
Keyword(s):  
Large Family ◽  
Modern Medicine ◽  
Entire Family ◽  
Postindustrial Society ◽  
Typical Member ◽  
Treatment And Prevention ◽  
Wide Range ◽  
High Prevalence ◽  
Lines Of Evidence

Several lines of evidence support the view that autism is a typical member of a large family of immune-related, noninfectious, chronic diseases associated with postindustrial society. This family of diseases includes a wide range of inflammatory, allergic, and autoimmune diseases and results from consequences of genetic/culture mismatches which profoundly destabilize the immune system. Principle among these consequences is depletion of important components, particularly helminths, from the ecosystem of the human body, the human biome. Autism shares a wide range of features in common with this family of diseases, including the contribution of genetics/epigenetics, the identification of disease-inducing triggers, the apparent role of immunity in pathogenesis, high prevalence, complex etiologies and manifestations, and potentially some aspects of epidemiology. Fortunately, using available resources and technology, modern medicine has the potential to effectively reconstitute the human biome, thus treating or even avoiding altogether the consequences of genetic/cultural mismatches which underpin this entire family of disease. Thus, if indeed autism is an epidemic of postindustrial society associated with immune hypersensitivity, we can expect that the disease is readily preventable.

scholarly journals Contributions of Distribution Modelling to the Ecological Study of Psittaciformes

Diversity ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 611
Author(s):  
José R. Ferrer-Paris ◽  
Ada Sánchez-Mercado
Keyword(s):  
Species Distribution ◽  
Abiotic Factors ◽  
Global Scale ◽  
Distribution Models ◽  
Wide Range ◽  
High Prevalence ◽  
Parrot Species ◽  
Nuanced Understanding ◽  
Research Action

We provide an overview of the use of species distribution modeling to address research questions related to parrot ecology and conservation at a global scale. We conducted a literature search and applied filters to select the 82 most relevant studies to discuss. The study of parrot species distribution has increased steadily in the past 30 years, with methods and computing development maturing and facilitating their application for a wide range of research and applied questions. Conservation topics was the most popular topic (37%), followed by ecology (34%) and invasion ecology (20%). The role of abiotic factors explaining parrot distribution is the most frequent ecological application. The high prevalence of studies supporting on-ground conservation problems is a remarkable example of reduction in the research–action gap. Prediction of invasion risk and assessment of invasion effect were more prevalent than examples evaluating the environmental or economic impact of these invasions. The integration of species distribution models with other tools in the decision-making process and other data (e.g., landscape metrics, genetic, behavior) could even further expand the range of applications and provide a more nuanced understanding of how parrot species are responding to their even more changing landscape and threats.

scholarly journals Prevalence of Salivary IgA Reacting with SARS-CoV-2 among Japanese People Unexposed to the Virus

2022 ◽  
Author(s):  
Keiichi Tsukinoki ◽  
Tetsuro Yamamoto ◽  
Jiro Saito ◽  
Wakako Sakaguchi ◽  
Keiichiro Iguchi ◽  
...  
Keyword(s):  
Public Health ◽  
Virus Infection ◽  
Host Defense ◽  
Negative Trend ◽  
Secretory Iga ◽  
Japanese People ◽  
Salivary Iga ◽  
Wide Range ◽  
High Prevalence

While the COVID-19 pandemic caused by SARS-CoV-2 has posed a threat to public health as the number of cases and COVID-19-related deaths are increasing worldwide, the incidence of the virus infection are extremely low in Japan compared with many other countries. To explore the reason for this strange phenomenon, we hypothesized the high prevalence of natural secretory IgA in saliva as mucosal IgA reacting with SARS-CoV-2, and thus surveyed the positivity for, as well as levels of, such reactive salivary IgA in a cohort of Japanese people of a wide range of age. The major findings were that 95/180 (52.78 %) of overall individuals who had not been exposed to SARS-CoV-2 were positive for salivary IgA with the levels ranging from 0.002 to 3.272 ng/ml, and that there may be a negative trend in positivity for salivary IgA according to age. These results suggest a role of mucosal IgA in host defense against SARS-CoV-2 infection.

scholarly journals Caring for transgender people: looking beyond the hype

Sexual Health ◽  
2017 ◽  
Vol 14 (5) ◽  
pp. 401
Author(s):  
Jason J. Ong ◽  
Darren B. Russell ◽  
Kevan Wylie
Keyword(s):  
Sexual Health ◽  
Legal Issues ◽  
Special Issue ◽  
Sexual Health Education ◽  
Transgender People ◽  
The People ◽  
Diagnostic Labels ◽  
Sexually Transmissible Infections ◽  
High Prevalence

This special issue of Sexual Health presents a collection of articles that addresses issues facing transgender individuals that are particularly challenging. Issues covered range from sexual health education in schools, the need for accurate epidemiological measurements, the perils of inaccurate diagnostic labels of transgender children, legal issues, the disproportionately high prevalence of HIV and sexually transmissible infections (STIs), and the role of primary care. We need to think critically, constructively and compassionately about transgender people. Particularly, we must look beyond the hype and objectively consider the evidence, without forgetting the people who are trying to cope with feelings that may be causing them great distress.

Protective Factors and Suicidality in Members of Arab Kindred

Crisis ◽  
2012 ◽  
Vol 33 (2) ◽  
pp. 80-86 ◽  
Author(s):  
Sami Hamdan ◽  
Nadine Melhem ◽  
Israel Orbach ◽  
Ilana Farbstein ◽  
Mohammad El-Haib ◽  
...  
Keyword(s):  
Risk Factors ◽  
Protective Factors ◽  
Suicidal Behavior ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Suicidal Risk ◽  
Arab Population ◽  
Psychiatric Interview ◽  
History Of

Background: Relatively little is known about the role of protective factors in an Arab population in the presence of suicidal risk factors. Aims: To examine the role of protective factors in a subsample of in large Arab Kindred participants in the presence of suicidal risk factors. Methods: We assessed protective and risk factors in a sample of 64 participants (16 suicidal and 48 nonsuicidal) between 15 and 55 years of age, using a comprehensive structured psychiatric interview, the Composite International Diagnostic Interview (CIDI), self-reported depression, anxiety, hopelessness, impulsivity, hostility, and suicidal behavior in first-degree and second-relatives. We also used the Religiosity Questionnaire and suicide attitude (SUIATT) and multidimensional perceived support scale. Results: Suicidal as opposed to nonsuicidal participants were more likely to have a lifetime history of major depressive disorder (MDD) (68.8% vs. 22.9% χ2 = 11.17, p = .001), an anxiety disorder (87.5% vs. 22.9, χ2 = 21.02, p < .001), or posttraumatic stress disorder (PTSD) (25% vs. 0.0%, Fisher’s, p = .003). Individuals who are otherwise at high risk for suicidality have a much lower risk when they experience higher perceived social support (3.31 ± 1.36 vs. 4.96 ± 1.40, t = 4.10, df = 62, p < .001), and they have the view that suicide is somehow unacceptable (1.83 ± .10 vs. 1.89 ± .07, t = 2.76, df = 60, p = .008). Conclusions: Taken together with other studies, these data suggest that the augmentation of protective factors could play a very important role in the prevention of incidental and recurrent suicidal behavior in Arab populations, where suicidal behavior in increasing rapidly.

Social Support, Emotional Intelligence, and Posttraumatic Stress Disorder Symptoms

2016 ◽  
Vol 37 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Nicole L. Hofman ◽  
Austin M. Hahn ◽  
Christine K. Tirabassi ◽  
Raluca M. Gaher
Keyword(s):  
Social Support ◽  
Posttraumatic Stress Disorder ◽  
Emotional Intelligence ◽  
Protective Factors ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Events ◽  
Ptsd Symptoms ◽  
The Relationship

Abstract. Exposure to traumatic events and the associated risk of developing Posttraumatic stress disorder (PTSD) symptoms is a significant and overlooked concern in the college population. It is important for current research to identify potential protective factors associated with the development and maintenance of PTSD symptoms unique to this population. Emotional intelligence and perceived social support are two identified protective factors that influence the association between exposure to traumatic events and PTSD symptomology. The current study examined the mediating role of social support in the relationship between emotional intelligence and PTSD symptoms. Participants included 443 trauma-exposed university students who completed online questionnaires. The results of this study indicated that social support mediates the relationship between emotional intelligence and reported PTSD symptoms. Thus, emotional intelligence is significantly associated with PTSD symptoms and social support may play an integral role in the relationship between emotional intelligence and PTSD. The current study is the first to investigate the role of social support in the relationship between emotional intelligence and PTSD symptoms. These findings have important treatment and prevention implications with regard to PTSD.

Moving toward well-being: The role of protective factors in violence research.

2015 ◽  
Vol 5 (4) ◽  
pp. 337-342 ◽  
Author(s):  
Chiara Sabina ◽  
Victoria Banyard
Keyword(s):  
Protective Factors ◽  
Well Being
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