scholarly journals Effects of Physical Training on Functional Status in Patients With Prolonged Mechanical Ventilation

2006 ◽  
Vol 86 (9) ◽  
pp. 1271-1281 ◽  
Author(s):  
Ling-Ling Chiang ◽  
Li-Ying Wang ◽  
Chin-Pyng Wu ◽  
Huey-Dong Wu ◽  
Ying-Tai Wu
Keyword(s):  
Mechanical Ventilation ◽  
Treatment Group ◽  
Muscle Strength ◽  
Functional Status ◽  
Physical Training ◽  
Prolonged Mechanical Ventilation ◽  
Free Time ◽  
Control Group ◽  
Limb Muscle ◽  
The Third

Abstract Background and Purpose. Patients requiring prolonged mechanical ventilation (PMV) are frequently deconditioned because of respiratory failure precipitated by the underlying disease, the adverse effects of medications, and a period of prolonged immobilization. The effects of 6 weeks of physical training on the strength of respiratory and limb muscles, on ventilator-free time, and on functional status in patients requiring PMV were examined. Subjects. Thirty-nine patients with PMV were initially enrolled in the study and were assigned to either a treatment group (n=20) or a control group (n=19). Three subjects in the treatment group and 4 subjects in the control group died during the 6-week intervention period and thus their data were excluded from the final analysis. Methods. Subjects in the treatment group received physical training 5 days a week for 6 weeks. Strength of respiratory and limb muscles, ventilator-free time, and functional status, which was measured by the Barthel Index of Activities of Daily Living (BI) and Functional Independence Measure (FIM), were examined at baseline and at the third and sixth weeks of the study period. Results. Respiratory and limb muscle strength improved significantly at the third and sixth weeks in the treatment group compared with baseline measurements. Total BI and FIM scores increased significantly in the treatment group and remained unchanged in the control group. Effect sizes of the BI and FIM scores were 2.02 and 1.93, respectively, at the sixth week. Discussion and Conclusion. The results show that a 6-week physical training program may improve limb muscle strength and ventilator-free time and thus improve functional outcomes in patients requiring PMV. [Chiang LL, Wang LY, Wu CP, et al. Effects of physical training on functional status in patients with prolonged mechanical ventilation. Phys Ther. 2006;86:1271–1281.]

scholarly journals Physical training is beneficial to functional status and survival in patients with prolonged mechanical ventilation

2011 ◽  
Vol 110 (9) ◽  
pp. 572-579 ◽  
Author(s):  
Shiauyee Chen ◽  
Chien-Ling Su ◽  
Ying-Tai Wu ◽  
Li-Ying Wang ◽  
Chin-Pyng Wu ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Functional Status ◽  
Physical Training ◽  
Prolonged Mechanical Ventilation

scholarly journals Effects of Exercise Training on Pulmonary Mechanics and Functional Status in Patients With Prolonged Mechanical Ventilation

2012 ◽  
Vol 57 (5) ◽  
pp. 727-734 ◽  
Author(s):  
Y.-H. Chen ◽  
H.-L. Lin ◽  
H.-F. Hsiao ◽  
L.-T. Chou ◽  
K.-C. Kao ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Exercise Training ◽  
Functional Status ◽  
Prolonged Mechanical Ventilation ◽  
Pulmonary Mechanics

scholarly journals Effects of theophylline therapy on respiratory muscle strength in patients with prolonged mechanical ventilation

Medicine ◽  
2019 ◽  
Vol 98 (2) ◽  
pp. e13982 ◽  
Author(s):  
Teng-Jen Yu ◽  
Yu-Chih Liu ◽  
Chien-Min Chu ◽  
Han-Chung Hu ◽  
Kuo-Chin Kao
Keyword(s):  
Mechanical Ventilation ◽  
Muscle Strength ◽  
Respiratory Muscle ◽  
Prolonged Mechanical Ventilation ◽  
Respiratory Muscle Strength

scholarly journals Effect of Glutamine Supplement Administration on the Reduction of Muscular Fatigue Post-Eccentric Exercise

2021 ◽  
Vol 55 (4) ◽  
pp. 275
Author(s):  
Afif Rusdiawan ◽  
Taufikkurrachman Taufikkurrachman
Keyword(s):  
Treatment Group ◽  
Muscle Strength ◽  
Knee Joint ◽  
Glutamine Supplementation ◽  
Control Group ◽  
Protein Levels ◽  
Drop Jumps ◽  
Post Test ◽  
The Mean ◽  
Leg Muscle

Eccentric activity can cause pain due to muscle damage and fatigue. Tired and damaged muscular state will degrade athletes' performance during a competition. Glutamine supplements are known to maintain plasma protein levels and can also improve muscle weakness due to inflammation that occurs after eccentric activity. The purpose of this study was to prove the effect of glutamine supplementation on the reduction of muscle fatigue after eccentric activity based on muscle strength and joint ROM. The subjects of this study were students of PJKR, IKIP Budi Utomo, who were randomly divided into 2 groups, the control group (K1) and treatment group (K2), each consisting of 22 respondents. The design of this research is randomized grsoup pre-test and post-test design. The eccentric activity performed was drop jumps on the bench with a height of 0.5 meters. Glutamine was administered orally after eccentric activity with a dose of 0.4 grams/kg BW in 450 ml water mineral 3 times (3 days). Measurement of Leg muscle strength was performed using Back and Leg Dynamometer by pulling with all the strength using leg muscles, whereas ROM measurements were measured using a goniometer performed on the knee joint in a passive way. The result of measurement obtained the mean of muscle strength of control group 63.7 ± 17.0 kg and treatment group 81.1 ± 17.0 kg at 72 hours. While result of ROM measurement obtained the mean of control group 124.3 ± 3.2 degrees and treatment group  131.7 ± 4.1 degrees at 72 hours. The analysis showed that glutamine administration in treatment group after eccentric activity increased leg muscle strength with p=0.000, and also increased knee joint ROM with p=0.000 at 72 hours after eccentric activity. In conclusion, glutamine administered with a dose of 0.4 gram/kg BW/day can increase leg muscle strength and knee joint ROM at 72 hours after eccentric activity.

scholarly journals PEMBERIAN TERAPI MURATTAL AL-QURAN TERHADAP KUALITAS TIDUR IBU HAMIL PRIMIGRAVIDA TRIMESTER III

2021 ◽  
Vol 7 (2) ◽  
pp. 287-294
Author(s):  
Noviyanti Noviyanti ◽  
Rahmi Rahmi ◽  
Ratna Dewi ◽  
Nurdahliana Nurdahliana
Keyword(s):  
Treatment Group ◽  
Sleep Quality ◽  
Pregnant Women ◽  
Wilcoxon Test ◽  
Control Group ◽  
Third Trimester ◽  
Control Group Design ◽  
Group Design ◽  
The Third

GIVING MURATTAL AL-QURAN THERAPY ON QUALITY TRIMESTER PRIMARY PREGNANT MOTHER'S SLEEP III Background : Expecting mothers experienced different discomforts which were frequently felt in the third trimester, a waiting period in which the pregnant mothers started to be alert of delivering a baby. These discomforts resulted in disturbance of activities of the expectants. Sleep problem was mostly occured during this trimester which might decrease sleep quality. To overcome the complaint, there should be a way to increase sleep quality of the pregnant women. One of them is Murattal Qur'an.Purpose : This study was aimed at finding out the effect of Murattal Qur'an on third semester toward sleep quality of the pregnants.Methods : This research belonged to a quasi-experimental with a pretest-posttest control group design. The population in this study were all pregnant women in the third trimester primigravida in the working area of the Kuta Baro Health Center, Aceh Besar. The sample was 40 pregnant women who were divided into the control group and the treatment group. The treatment group listened to the Murattal Quran chapter Ar-Rahman on Android for 7 nights before going to bed. Data was  analysed by using the Wilcoxon test because the data were not normally distributed.Results : The obtained significant value (p) of  the treatment group of before and after  therapy was  0.000 lower than 0.05 (p=0.000 <0.05)Conclusion : There is an effect of giving Murattal Al-Quran therapy in the third trimester primigravida on the quality of mother's sleep.Suggestion : It hoped that it increased the active role of Midwives to provide information to pregnant women about the way to overcome the sleep disorders of   the third trimester pregnant women was by by listening to the murattal Quran. Keywords: Murattal Al-Quran, Sleep Quality, Primigravida, Third Trimester.ABSTRAK Latar Belakang :  Ketidaknyamanan yang dirasakan oleh ibu hamil paling sering dirasakan saat trimester III. Trimester III merupakan masa menunggu kelahiran bayinya. Ketidaknyamanan yang dirasakan ibu mengakibatkan aktivitas sehari-hari ibu hamil menjadi terganggu. Gangguan tidur merupakan Keluhan yang paling sering terjadi pada ibu hamil trimester III. Gangguan ini menyebabkan kualitas tidur ibu menurun. Salah satu cara pendekatan untuk meningkatkan kualitas tidur ibu hamil adalah mendengarkan lantunan ayat Al-Quran.Tujuan : Mengetahui pengaruh pemberian terapi murattal Al-Quran pada primigravida trimester III terhadap kualitas tidur ibu.Metode : Jenis penelitian adalah quasi-eksperimen dengan pendekatan pretest-posttest control group design. Populasi adalah primigravida trimester III di wilayah kerja Puskesmas Kuta Baro Kabupaten Aceh Besar. Jumlah sampel 40 ibu hamil yang dibagi menjadi kelompok kontrol dan kelompok perlakuan. Kelompok perlakuan mendengarkan murattal Al-Quran surah Ar-Rahman dengan menggunakan HP Android selama 7 malam sebelum tidur. Analisa data menggunakan Uji Wilcoxon karena data berdistribusi tidak normal.Hasil :  Nilai signifikan pada kelompok perlakuan terhadap kualitas tidur ibu sebelum dan sesudah diberikan terapi adalah p = 0,000 lebih kecil dari nilai 0,05.Kesimpulan : Terdapat pengaruh pemberian terapi murattal Al-Quran pada primigravida trimester III terhadap kualitas tidur ibu.Saran : Meningkatkan peran aktif bidan dalam memberikan informasi kepada ibu hamil tentang asuhan ketidaknyaman ibu hamil trimester III yaitu masalah gangguan tidur dengan mendengarkan murattal Al-Quran.  Kata Kunci: Murattal Al-Quran, Kualitas tidur, Primigravida, Trimester III. 

scholarly journals Effect of Leaf Syzygium aromaticum on Lymphocytes and Macrophages Mice Balb/c

2018 ◽  
Vol 23 (2) ◽  
pp. 79
Author(s):  
Syahran Wael ◽  
Theopilus Wilhelmus Watuguly ◽  
Didik Wahyudi
Keyword(s):  
Treatment Group ◽  
Salmonella Typhimurium ◽  
Lymphocyte Proliferation ◽  
The Body ◽  
Control Group ◽  
Syzygium Aromaticum ◽  
The Third ◽  
Significant Difference ◽  
Post Test ◽  
Proliferation Of Lymphocytes

Syzygium aromaticum as an immunomodulator contains main active compound eugenol which is able to stimulate lymphocyte proliferation and the production of macrophages. Lymphocytes have a very important role to provide protection in the body against infection. This study aims to prove the effects of extract Syzygium aromaticum leaf against increased proliferation of lymphocytes, lymphoblast and macrophages of mice Balb/c of induced Salmonella typhimurium. The method used in this study was experimental with post test only control group. Mice Balb/c were divided into 4 groups as a control group and treatment induced of Salmonella typhimurium. The first treatment group were administrated extracts of 15mg /kgbw, the second treatment 75mg/kgbw, the third treatment of 150mg/kgbw for 12days. ANOVA test showed a significant difference in lymphocyte proliferation but not lymphoblast and macrophages.

scholarly journals The effect of carprofen on fresh dairy cows health

2019 ◽  
Vol 26 (1) ◽  
Author(s):  
Gabrielė Lošytė ◽  
Ieva Navalinskaitė ◽  
Žyginta Prokopavičiūtė ◽  
Ernesta Pocevičienė ◽  
Ramūnas Antanaitis
Keyword(s):  
Treatment Group ◽  
Dairy Cows ◽  
Somatic Cell Count ◽  
Plasma Concentrations ◽  
Milk Composition ◽  
Management Program ◽  
Control Group ◽  
Stress Indicator ◽  
The Third ◽  
The Impact

The aim of this study was to evaluate the impact of stress on the health of fresh-lactation cows and the effect of NSAIDs on the stress indicator cortisol, rumination time (RT) and somatic cell count (SCC). The treatment group of cows (TG) (n = 15) were given a subcutaneous injection of Rimadyl Cattle® (50 mg/ml of carprofen), 1.4 mg per 1 kg BW dose, up to 1 hour after calving. At the same time, the control group of cows (CG) (n = 15) were given an injection of 0.9% NaCl. The whole study looked at the health of cows by recording cases that occurred during the period after calving. Blood cortisol examination was performed within 2, 24 and 48 h after the use of the mentioned drugs. Rumination time was registered with the Lely T4C management program for analysis. Milk composition (SCC) was determined using the Lely T4C management program for analysis. NSAIDs (carprofen 50 mg/ml) statistically significantly reduced cortisol plasma concentrations within 48 h from the use of the drug and did not have an impact on SCC. The use of NSAID increased the average ruminating time from the third to the eleventh day after calving.

scholarly journals Effect of Ischemic Conditioning on Some Motor and Cognitive Factors in the Ovariectomy-Induced Aged Rats

2021 ◽  
Author(s):  
Sajjad Sattai Mokhtari ◽  
Elham Hakimizadeh ◽  
Mojdeh Haj Mohammadi ◽  
Ayat Kaeidi ◽  
Iman Fatemi ◽  
...  
Keyword(s):  
Treatment Group ◽  
Muscle Strength ◽  
Forced Swim Test ◽  
Treatment Options ◽  
Female Rats ◽  
Ovariectomized Rats ◽  
Control Group ◽  
Balance Function ◽  
Balance Performance ◽  
Ischemic Conditioning

Introduction: During menopause, which is a part of the aging process in women, the level of sex hormones decreases, which causes problems such as memory impairment and cognitive functions. One of the treatment options for these disorders is hormone therapy, which has several side effects. The present study investigated the effect of remote ischemic conditioning (RIC) technique on memory improvement, muscle strength, motor and balance function in ovariectomized rats. Methods: In the present experimental study, 24 Wistar female rats with an approximate weight of (170-220 g) were divided into three groups (n = 8) including, 1: control group, 2: ovariectomy group and 3: ovariectomy+ treatment group. Initially, the animals in the second and third groups underwent ovariectomy surgery. The RIC techniques were performed on treatment group of rats for two months. After that, memory, muscle strength, and motor and balance function were assessed in all groups. SPSS software (V21) and one-way analysis of variance were used for statistical analysis. Results: The result of this study showed that RIC technique significantly improved memory in the ovariectomy+treatment group in comparison with the ovariectomy group (P <0.04). The results of forced swim test showed that RIC technique significant increase muscle strength in the ovariectomy+treatment group compared to the ovariectomy group (P <0.0281).The result of motor and balance performance did not show any significant improvement. Conclusion: RIC technique can have beneficial effects on menopausal-related disorders and ovariectomy.

scholarly journals Effects of high-flow oxygen therapy on patients with hypoxemia after extubation and predictors of reintubation: a retrospective study based on the MIMIC-IV database

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Taotao Liu ◽  
Qinyu Zhao ◽  
Bin Du
Keyword(s):  
Mechanical Ventilation ◽  
Treatment Group ◽  
Medical Information ◽  
Characteristic Curve ◽  
Oxygenation Index ◽  
High Flow ◽  
Control Group ◽  
Severe Hypoxemia ◽  
High Flow Oxygen ◽  
Weaning Failure

Abstract Background To investigate the indications for high-flow nasal cannula oxygen (HFNC) therapy in patients with hypoxemia during ventilator weaning and to explore the predictors of reintubation when treatment fails. Methods Adult patients with hypoxemia weaning from mechanical ventilation were identified from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. The patients were assigned to the treatment group or control group according to whether they were receiving HFNC or non-invasive ventilation (NIV) after extubation. The 28-day mortality and 28-day reintubation rates were compared between the two groups after Propensity score matching (PSM). The predictor for reintubation was formulated according to the risk factors with the XGBoost algorithm. The areas under the receiver operating characteristic curve (AUC) was calculated for reintubation prediction according to values at 4 h after extubation, which was compared with the ratio of SpO2/FiO2 to respiratory rate (ROX index). Results A total of 524,520 medical records were screened, and 801 patients with moderate or severe hypoxemia when undergoing mechanical ventilation weaning were included (100 < PaO2/FiO2 ≤ 300 mmHg), including 358 patients who received HFNC therapy after extubation in the treatment group. There were 315 patients with severe hypoxemia (100 < PaO2/FiO2 ≤ 200 mmHg) before extubation, and 190 patients remained in the treatment group with median oxygenation index 166[157,180] mmHg after PSM. There were no significant differences in the 28-day reintubation rate or 28-day mortality between the two groups with moderate or severe hypoxemia (all P > 0.05). Then HR/SpO2 was formulated as a predictor for 48-h reintubation according to the important features predicting weaning failure. According to values at 4 h after extubation, the AUC of HR/SpO2 was 0.657, which was larger than that of ROX index (0.583). When the HR/SpO2 reached 1.2 at 4 h after extubation, the specificity for 48-h reintubation prediction was 93%. Conclusions The treatment effect of HFNC therapy is not inferior to that of NIV, even on patients with oxygenation index from 160 to 180 mmHg when weaning from ventilator. HR/SpO2 is more early and accurate in predicting HFNC failure than ROX index.

scholarly journals Implementation of Nurse-Led, Goal-Directed Lung Physiotherapy for Older Patients With Sepsis and Pneumonia in the ICU

2021 ◽  
Vol 8 ◽  
Author(s):  
Jianhua Sun ◽  
Na Cui ◽  
Wen Han ◽  
Qi Li ◽  
Hao Wang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Treatment Group ◽  
Older Patients ◽  
Control Group ◽  
Icu Mortality ◽  
Two Phase ◽  
Before And After ◽  
Before And After Study

Objectives: This study aimed to investigate the effect of nurse-led, goal-directed lung physiotherapy (GDLPT) on the prognosis of older patients with sepsis caused by pneumonia in the intensive care unit.Methods: We conducted a prospective, two-phase (before-and-after) study over 3 years called the GDLPT study. All patients received standard lung therapy for sepsis caused by pneumonia and patients in phase 2 also received GDLPT. In this study, 253 older patients (age ≥ 65 years) with sepsis and pneumonia were retrospectively analyzed. The main outcome was 28 day mortality.Results: Among 742 patients with sepsis, 253 older patients with pneumonia were divided into the control group and the treatment group. Patients in the treatment group had a significantly shorter duration of mechanical ventilation [5 (4, 6) vs. 5 (4, 8) days; P = 0.045], and a lower risk of intensive care unit (ICU) mortality [14.5% (24/166) vs. 28.7% (25/87); P = 0.008] and 28 day mortality [15.1% (25/166) vs. 31% (27/87); P = 0.005] compared with those in the control group. GDLPT was an independent risk factor for 28 day mortality [odds ratio (OR), 0.379; 95% confidence interval (CI), 0.187–0.766; P = 0.007].Conclusions: Nurse-led GDLPT shortens the duration of mechanical ventilation, decreases ICU and 28-day mortality, and improves the prognosis of older patients with sepsis and pneumonia in the ICU.

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