Bacterial culture of septic synovial structures of horses: Does a positive bacterial culture influence prognosis?

2010 ◽  
Vol 42 (3) ◽  
pp. 213-218 ◽  
Author(s):  
A. H. TAYLOR ◽  
T. S. MAIR ◽  
L. J. SMITH ◽  
J. D. PERKINS
Keyword(s):  
Bacterial Culture ◽  
Positive Bacterial Culture ◽  
Culture Influence

Etiology of Pertussis Syndrome

PEDIATRICS ◽  
1980 ◽  
Vol 66 (1) ◽  
pp. 50-55
Author(s):  
Margaret A. Keller ◽  
Rouben Aftandelians ◽  
James D. Connor
Keyword(s):  
Bordetella Pertussis ◽  
Bacterial Culture ◽  
Index Case ◽  
Family Group ◽  
Isolation Rate ◽  
Bordetella Parapertussis ◽  
Positive Bacterial Culture ◽  
Serologic Evidence ◽  
Family Contact ◽  
Culture Negative

One hundred patients with clinical pertussis were studied to determine the etiology of pertussis syndrome. Forty-two (42%) of the patients had either Bordetella pertussis or Bordetella parapertussis isolated from the nasopharynx. In an additional 36 (36%) patients, B pertussis was isolated from the nasopharynx of the associated index case or family contact case. Thus, Bordetella was isolated from 78 (78%) of the patients or from their immediate family group. Of the 22 culture-negative patients residing in culture-negative families, 12 had serologic evidence of Bordetella infection and another was from a family group in which two members were seropositive. Therefore, 91 patients (91%) had bacteriologic or serologic evidence of Bordetella infection themselves or within their families. Viral cultures were obtained on 75 of the patients. Adenoviruses were isolated from 33% of those with positive cultures for B pertussis and from 14% of those with negative cultures. In the group without direct or indirect, bacteriologic or serologic evidence of Bordetella infection, the adenoviral isolation rate (13%) was not significantly different from the adenoviral isolation rate (33%) in patients with a positive bacterial culture. These data do not support a role for adenovirus alone in causing pertussis syndrome.

The Effects of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor Gel on Third-Degree Frostbite Wounds in Northeastern China: A Randomized Controlled Trial

2020 ◽  
Author(s):  
Xiu-Hang Zhang ◽  
Chang-Lei Cui ◽  
Hao-Yue Zhu ◽  
Jian Wang ◽  
Yan Xue ◽  
...  
Keyword(s):  
Bacterial Culture ◽  
Controlled Trial ◽  
Healing Time ◽  
Control Group ◽  
Fisher Exact Test ◽  
Chi Square ◽  
Exact Test ◽  
Positive Effects ◽  
Positive Bacterial Culture ◽  
Better Than

Abstract The aim of the study was to investigate the effects of the rhGM-CSF gel on third-degree frostbite wounds. Sixty-two patients who had suffered third-degree frostbite on their hand or foot (91 wounds in total) were selected using a convenience sampling method and randomly allocated to two groups: the rhGM-CSF group(31patients,45 frostbite wounds) received the rhGM-CSF gel when wound dressing change daily; however, the control group (31patients, 46 frostbite wounds) received aloe glue. The wound healing time, the score of inflammation about the wound and the positive bacterial culture of wound secretions were used to measure outcomes, respectively. Data were analyzed using SPSS (25.0), Student’s t test or Mann–Whitney U test and chi-square test or Fisher exact test were selected, as appropriate. The healing time of the rhGM-CSF group was (12.2 ± 5.0) days, which was significantly shorter than that of the control group (15.5 ± 4.7) days (P < .0001). The rhGM-CSF group’s wound inflammation scores on the 7th and 14th day of treatment were (0.96 ± 0.21) and (1.88 ± 0.29), respectively, which were better than those of the control group (1.12 ± 0.24) and (1.38 ± 0.15) (both P < .0001). The positive bacterial culture of wound secretions in the rhGM-CSF group was also better than that in the control group on the 3rd, 7th, and 14th day after treatment (P = .027, .004, .030, respectively). According to the results, using rhGM-CSF gel considerably increases the speed of frostbite wounds healing, and have an effect on protecting third-degree frostbite wounds regarding the positive effects. Trial Registration: This trial was registered in the Chinese Clinical Trial Register, ChiCTR1900021299.

Tibial plateau levelling osteotomy implant removal: A retrospective analysis of 129 cases

2011 ◽  
Vol 24 (06) ◽  
pp. 450-456 ◽  
Author(s):  
M. S. Bergh ◽  
C. Wang ◽  
K. Wells ◽  
A. M. Thompson
Keyword(s):  
Tibial Plateau ◽  
Bacterial Culture ◽  
Statistical Significance ◽  
Clinical Signs ◽  
Antibiotic Use ◽  
Implant Removal ◽  
Time Interval ◽  
Exact Test ◽  
Positive Bacterial Culture ◽  
Operative Findings

SummaryObjective: To evaluate a cohort of dogs undergoing tibial plateau levelling osteotomy (TPLO) implant removal to determine key clinical features, prevalence, and indications for implant removal.Methods: Medical records of dogs undergoing TPLO implant removal at a private referral practice (Dallas Veterinary Surgical Center) between 2004–2008 were reviewed. Patient signalment, implant type, presence of concurrent medical disease, surgeon, antibiotic use, aerobic bacterial culture result, and operative findings were recorded. Data were analyzed using paired t-test, Fisher’s exact test, and Wilcoxon-rank sum test. Statistical significance was set at p <0.05.Results: The TPLO implants were removed from 126 dogs (n = 129, 4.8% of TPLO procedures) during the study period. Average time interval from TPLO to implant removal was 16.0 ± 17.8 months. The most common clinical signs were the presence of an open wound (n = 80), draining tract (n = 64), and lameness (n = 59). Culture of tissue or fluid from the implant bed or implants was positive for bacterial growth in 95/115 cases. A significantly greater proportion of the implants removed were Slocum TPLO plates (n = 109 6.1%) when compared to other TPLO plate types (n = 20 2.3%) (p <0.0001). No association was identified between a positive bacterial culture and measured variables.Clinical significance: Local bacterial infection and clinical signs of inflammation were the most common reasons for TPLO implant removal. There may be an increased implant-associated complication rate for Slocum TPLO plates in the study population.

scholarly journals Associations Between Procalcitonin and Markers of Bacterial Sepsis

Medicina ◽  
2012 ◽  
Vol 48 (8) ◽  
pp. 57 ◽  
Author(s):  
Veeresh Patil ◽  
Jaymin Morjaria ◽  
Francois De Villers ◽  
Suresh Babu
Keyword(s):  
Bacterial Culture ◽  
White Cell Count ◽  
Bacterial Sepsis ◽  
Reactive Protein ◽  
Paired Samples ◽  
Positive Bacterial Culture ◽  
Specificity And Sensitivity ◽  
Significant Difference ◽  
Culture Positive ◽  
Culture Negative

Background. Bacterial sepsis with no bacterial isolates can be a difficult clinical conundrum, where other markers like C-reactive protein (CRP), white cell count (WCC), and neutrophilia are helpful to arrive at a diagnosis. Procalcitonin (PCT) has been shown to be a useful biomarker in bacterial sepsis. The aim of the study was to look at the association of PCT with bacterial cultures and compare this to currently used markers of bacterial sepsis. Material and Methods. WCC, neutrophil count, and CRP with PCT were compared in patients with a positive bacterial culture from blood/body fluid. The specificity and sensitivity of PCT were compared with those of CRP. Results. Of the 99 paired samples obtained, 25 cultures were positive for bacteria. There was a significant difference in CRP (P=0.04) and PCT (P<0.001) levels between culture-positive and culture-negative samples. PCT had a better sensitivity and specificity than CRP (84% and 64.9% vs. 69.6% and 52.9%, respectively), with a combined specificity (CRP and PCT) of 83.5%. Conclusions. PCT has a better association with bacterial sepsis and is superior to currently available biomarkers in the clinical setting. The rapid pharmacodynamics of PCT can serve as an early predictor of the diagnosis of bacterial sepsis while awaiting the bacterial culture results avoiding undue delay in the institution of antibiotics, hence, potentially improving the prognosis of patients with bacterial sepsis.

Positive Bacterial Culture Results at a Dermatologic Surgery Center

2020 ◽  
Vol 46 (6) ◽  
pp. 773-779
Author(s):  
Jessica B. Dietert ◽  
James Ko ◽  
Eva. A. Hurst
Keyword(s):  
Bacterial Culture ◽  
Dermatologic Surgery ◽  
Positive Bacterial Culture ◽  
Surgery Center

Surveillance of Infections Associated With Intravenous Catheters in Dogs and Cats in an Intensive Care Unit

2007 ◽  
Vol 43 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Michelle L. Marsh-Ng ◽  
Derek P. Burney ◽  
Jennifer Garcia
Keyword(s):  
Bacterial Culture ◽  
Bacterial Colonization ◽  
Factors Associated ◽  
Bacterial Cultures ◽  
Positive Bacterial Culture ◽  
Increased Risk ◽  
Catheter Tip ◽  
Intravenous Catheters ◽  
Aerobic And Anaerobic ◽  
Catheter Location

Positive catheter-tip culture rates and risk factors associated with bacterial colonization of intravenous (IV) catheters were assessed in dogs and cats. Aerobic and anaerobic bacterial cultures were performed on 151 catheters, and 24.5% were positive. Of the positive cultures, 46.0% grew Enterobacter spp. The type of catheter used, blood sampling through the catheter, the type of IV infusate administered, the duration the catheter was in place, the catheter location, complications with the catheter, and the final outcome of the animal were not associated with an increased risk of a positive bacterial culture from the catheter tip.

Microorganisms in Chronic Otitis Media with Effusion

1976 ◽  
Vol 85 (2_suppl) ◽  
pp. 245-249 ◽  
Author(s):  
Yea Sang Liu ◽  
David J. Lim ◽  
Raymond Lang ◽  
Herbert G. Birck
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Bacterial Culture ◽  
Otitis Media With Effusion ◽  
Chronic Otitis Media ◽  
Present Series ◽  
Positive Bacterial Culture ◽  
High Incidence

A total of 175 effusions obtained from 172 patients suffering from chronic otitis media with effusions was examined for bacterial smear and culture. Eighty percent showed positive bacterial smear, but only 49% yielded positive bacterial culture. The mucoid effusions had positive cultures in only 37%, whereas the bacterial culture rate was higher in serous (59%) and leukocytic (64%) types. The isolation of common pathogens accounted for about 50% of the isolates, and nonpathogens accounted for the remaining 50%. The high incidence of microorganisms in the middle ear effusions in the present series raises the possibility of bacterial contribution in many cases of OME.

scholarly journals Antimicrobial Susceptibility among Pathogens Isolated in Early- versus Late-Onset Ventilator-Associated Pneumonia

2021 ◽  
Vol 13 (2) ◽  
pp. 401-410
Author(s):  
Hend Ben Lakhal ◽  
Aymen M’Rad ◽  
Thierry Naas ◽  
Nozha Brahmi
Keyword(s):  
Early Onset ◽  
Bacterial Culture ◽  
Late Onset ◽  
Multidrug Resistant ◽  
First Episode ◽  
High Morbidity ◽  
Ventilator Associated Pneumonia ◽  
Bacterial Isolates ◽  
Positive Bacterial Culture ◽  
Significant Difference

Ventilator-associated pneumonia (VAP) is associated with increased hospital stay and high morbidity and mortality in critically ill patients. The aims of this study were to (i) determine the incidence of multidrug-resistant (MDR) pathogens in the first episodes of VAP and to assess potential differences in bacterial profiles of subjects with early- versus late-onset VAP. This was a retrospective cohort study over a period of 18 months including all patients who had a first episode of VAP confirmed by positive bacterial culture. Subjects were distributed into two groups according to the number of intubation days: early-onset VAP (<5 days) or late-onset VAP (≥5 days). The primary endpoint was the nature of causative pathogens and their resistance profiles. Sixty patients were included, 29 men and 31 women, with an average age of 38 ± 16 years. The IGS 2 at admission was 40.5 [32–44] and APACHE was 19 [15–22]. Monomicrobial infections were diagnosed in 77% of patients (n = 46). The most frequently isolated bacteria were A. baumannii, 53% (n = 32); P. aeruginosa in 37% (n = 22); Enterobacterales in 28% (n = 17) and S. aureus in 5% (n = 3). Ninety-seven percent of the bacteria were MDR. The VAP group comprised 36 (60%) episodes of early-onset VAP and 24 (40%) episodes of late-onset VAP. There was no significant difference in the distribution of the bacterial isolates, nor in terms of antibacterial resistances between early- and late-onset VAPs. Our data support recent observations that there is no microbiological difference in the prevalence of potential MDR pathogens or in their resistance profiles associated with early- versus late-onset VAPs, especially in countries with high rates of MDR bacteria.

scholarly journals The Formation of Biofilm and Bacteriology in Otitis Media with Effusion in Children: A Prospective Cross-Sectional Study

2021 ◽  
Vol 18 (7) ◽  
pp. 3555
Author(s):  
Artur Niedzielski ◽  
Lechosław Paweł Chmielik ◽  
Tomasz Stankiewicz
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Otitis Media ◽  
Pathogenic Bacteria ◽  
Bacterial Culture ◽  
Otitis Media With Effusion ◽  
Cross Sectional ◽  
Opportunistic Bacteria ◽  
Positive Bacterial Culture ◽  
Staphylococcus Spp

Background: Otitis media with effusion (OME) can cause serious complications such as hearing impairment or development delays. The aim of the study was to assess the microbiological profile of organisms responsible for OME and to determine if a biofilm formation can be observed. Methods: Ninety-nine samples from 76 patients aged from 6 months to 12 years were collected for microbiological and molecular studies. Results: In microbiological studies, pathogenic bacteria Haemophilus influenzae (38.89%), Streptococcus pneumoniae (33.33%), and Staphylococcus aureus MSSA (27.78%), as well as opportunistic bacteria Staphylococcus spp. (74.14%), Diphtheroids (20.69%), Streptococcus viridans (3.45%), and Neisseria spp. (1.72%) were found. The average degree of hearing loss in the group of children with positive bacterial culture was 35.9 dB, while in the group with negative bacterial culture it was 25.9 dB (p = 0.0008). The type of cultured bacteria had a significant impact on the degree of hearing impairment in children (p = 0.0192). In total, 37.5% of Staphylococcus spp. strains were able to form biofilm. Conclusions: Staphylococcus spp. in OME may form biofilms, which can explain the chronic character of the disease. Pathogenic and opportunistic bacteria may be involved in the etiopathogenesis of OME. The degree of hearing loss was significantly higher in patients from which the positive bacterial cultures were obtained.

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