scholarly journals PHARMACEUTICO - ANALYTICAL STANDARDIZATION OF AJAMODADI CHOORNA AND ITS DRUG MODIFICATION AS AJAMODADI CHEWABLE TABLET

2019 ◽  
Vol 7 (8) ◽  
pp. 431-437
Author(s):  
Abhilash Rajendra Dharamthok ◽  
Mahantesh. B. Rudrapuri ◽  
G. Vinay Mohan
Keyword(s):  
Ayurvedic Medicine ◽  
Chewable Tablet ◽  
Ancient Science ◽  
Classical Formulation ◽  
Drug Modification ◽  
Herbal Formulations

Ayurveda is ancient science. Acharya motioned chatushpada which is bhishak, dravya, rogi, upstatha. In which dravya means ayurvedic medicine Standardization of herbal formulations is important to calculate the quality of drugs, based on the concentration of their active principles. Ajamodadi Choorna is a classical formulation mentioned in Bhaisajyaratnavali with the indication Swarbheda This article highlights on pharmaceutico - analytical standardization of ajamodadi choorna and its drug modification as Ajamodadi chewable tablet standardization of Ajmodadi churna.

Pharmaceutical evaluation of Haridra Khanda tablet

2020 ◽  
Vol 5 (05) ◽  
pp. 175-178
Author(s):  
Makrand A. Sonare ◽  
Manoj Kumar Samantaray
Keyword(s):  
Dosage Form ◽  
Ayurvedic Medicine ◽  
Pediatric Practice ◽  
Classical Formulation ◽  
Binding Agents

Haridra Khanda is unique classical formulation indicated in Udarda, Shitapitta, Kotha. (Urticarial rashes) Khanda or Granules are a comparatively unusual means of administering drugs that possess an unpleasant taste. Haridra Khanda is classical Ayurvedic medicine and available market. Keeping the issue of palatability and invention of patient friendly dosage form in mind, the efforts was made for preparation of tablet out of classical Ayurvedic formulation - Haridra Khanda. The preparation of Haridra Khanda granules were made by standard operative procedure.Binding agents were added to Haridra Khanda . Haridra Khanda was added to mass mixer to ensure homogeneity and easy mixing of all binding agents. And later this mixture was subjected to single punch tablet machine for preparation of 1000 mg tablet. All the Analytical parameters were passed by the Haridra Khanda tablets. Physician can prescribed the tablets to the patients which feel the powdered dosage uncomfortable. Depending on the Roga and Rogibala, tablets of various sizes can be punched and used clinically. This can work more efficiently in pediatric practice.

scholarly journals In house & Marketed Preparation of Hingwashtak Churna, A Polyherbal Formulation: Comparative Standardization and Measures

2018 ◽  
Vol 5 (1) ◽  
pp. 76-83
Author(s):  
Rashmi Saxena Pal ◽  
Yogendra Pal ◽  
Pranay Wal ◽  
Ankita Wal
Keyword(s):  
Ayurvedic Medicine ◽  
Chemical Parameters ◽  
Standard Preparation ◽  
Physical Constants ◽  
Polyherbal Formulation ◽  
Classical Formulation ◽  
Physico Chemical ◽  
Digestive Disorders

Background: Hingwashtak Churṇa is a polyherbal Ayurveda based classical formulation used to cure certain digestive disorders. We have attempted to prepare and standardize this preparation comparing it with standard preparation to ensure its quality. Objective: The current research was aimed at the preparation of Churna in house and to compare it with the marketed formulation on all the standard norms while standardizing it. Materials and Methods: The Churna was prepared in-house according to The Ayurvedic Formulary of India. The Churna was comparatively evaluated along with its marketed preparation based on the evaluation of external features, physical constants, and physico-chemical parameters. Results: The scientific findings were found to be comparable and suitable enough for the evaluation of Churṇa. Conclusion: Ayurvedic medicine, HW has been standardized using the various parameters and can be incorporated while developing the pharmacopoeial standards.

scholarly journals An Ayurvedic Management of Sickle Cell Anemia in Children: A case study

2021 ◽  
Vol 12 (3) ◽  
pp. 714-717
Author(s):  
Akriti Gupta ◽  
Swapnil Raskar
Keyword(s):  
Quality Of Life ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Globin Gene ◽  
Genetic Diseases ◽  
Single Amino Acid ◽  
Ayurvedic Medicine ◽  
Chromosome 11

Introduction:- Sickle cell anemia is a term for a group of genetic diseases characterized by the production of hemoglobin (Hb) "S". This is the result of replacing the base pair thymine at the 6th position of the β-globin gene on chromosome 11 with adenine and replacing valine with glutamic acid. A single amino acid substitution is the reason for the profound changes in the stability and solubility of the hemoglobin "S" molecule. Due to its chronic nature and painful crisis, children’s quality of life is difficult. From now on, there is no final treatment other than a successful bone marrow transplant. Its symptoms and the nature of the disease can be compared with Pandu. If a drug improves the quality of life and maintains the health of the patient, then the drug and efforts will be beneficial to society. Material and Methods:- A 9-year-old male patient was diagnosed with sickle cell anemia. Symptoms include joint and limb pain, anorexia, fatigue, loss of appetite, and weight loss. approached the OPD, department of Kaumarbhritya, Parul Institute of Ayurved, Vadodara.  Observations and Results:-The patient is taking modern medicine (1 mg folic acid once a day). The Childs parents also wanted to take Ayurvedic medicine, so they came here for 2 months of Ayurvedic medicine treatment, during which he did not have a pain crisis.Weight improved From 16 kg to 18 kg.The quality of life of a patient is also improved. Conclusion:-Therefore, the purpose of this case study is to study the pathophysiology and treatment of sickle cell anemia from an Ayurvedic perspective and to study the possible mechanism of action of the drug.

scholarly journals Uji Mutu Fisik Metoklopramid HCl Tablet Chewable dengan Variasi Jenis Pengisi sebagai Diluent menggunakan Metode Granulasi Basah

2021 ◽  
Vol 1 (2) ◽  
pp. 76-85
Author(s):  
Umi Latifiana ◽  
Deny Budi Legowo ◽  
Erna Fitriany ◽  
Andri Priyoherianto ◽  
Muhammad Novianto Ainul Huri
Keyword(s):  
New Product ◽  
Wet Granulation ◽  
Test Results ◽  
Quality Test ◽  
Disintegration Time ◽  
Chewable Tablet ◽  
Physical Quality ◽  
Chewable Tablets ◽  
Tablet Hardness

Metoclopramide HCl are used to reduce vomiting and nausea. The availability on the market in the form of tablet, syrup and injection. Patient tend to prefer take drugs by oral use because it was easier. Chewable tablet is the new product as the alternative ways to treatment children and adult patient who had difficulity problem of swallowing drugs. Objectives: This research aims to formulate the chewable metoclopramide HCl tablets using diluent variations to get a better physical quality test. Chewable tablets of metoclopramide HCl are made using diluent variations, they are mannitol, sucrose, lactose. Formula I mannitol, formula II sucrose, and formula III lactose. Chewable tablet preparations are made by the wet granulation method. Data collection was performed on physical characteristics including organoleptic, weight uniformity, uniformity of size, tablet hardness, tablet fragility, disintegration time, metoclopramide HCl levels. Physical quality test results were statistically analyzed to determine the effect of variations in the diluent on the characteristics of chewable tablets. The results of this research have an influence on the physical quality and uniformity of contents of various types of diluent variations between each formulation. In this research, fillers have an important role in the preparation of chewable metoclopramide tablets to determine the physical quality of the tablets and the uniformity of their contents. The variation of diluent that gives better results is mannitol. This is because formulas that use mannitol have uniformity in content that meets the requirements, faster disintegration time, and physical quality of tablets that still meet the requirements, when compared to the first and second formulations. The variation of diluent that gives better results is mannitol.

Phytopharmaceutical potential of Anthocephalus cadamba (Roxb.)

2021 ◽  
Vol 16 (12) ◽  
pp. 150-160
Author(s):  
T. Sharma ◽  
V. Khandelwal
Keyword(s):  
Skin Diseases ◽  
Biologically Active ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Tropical Regions ◽  
The Family ◽  
Ancient Times ◽  
Herbal Formulations ◽  
Anthocephalus Cadamba

Ever since ancient times, medicinal plants served as a great source of herbal formulations which can confer human civilization with preferential quality of life. Among them, some plants secured their position in mythologies, also highlighting Anthocephalus cadamba, a religious medicinal plant, belonging to the family Rubiaceae, mostly cultivated in tropical regions. Conventional medicinal system of India provides evidences regarding folk medicinal uses for the treatment of various ailments like inflammation, skin diseases, uterine complaints, blood disease and diarrhea etc. Phytochemical investigations revealed the presence of some biologically active compounds like flavonoids, alkaloids, coumarins, terpenoids, diterpenoids, triterpenes, glycosides, sterols, amides and fatty acids and these compounds were found to be accountable for various pharmacological activities such as antimicrobial, antipyretic, anti-inflammatory, analgesic, anticancerous, antidibetic, hypolipidemic, antihepatotoxic, antidiarrhoel, diuretic, laxative, antioxidant, immunomodulatory, wound healing etc.

Practical veiw of kadali kshara preparation

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
Vasant Panchal
Keyword(s):  
Standard Procedure ◽  
Standard Operating Procedure ◽  
Healthy Person ◽  
Raw Material ◽  
Ayurvedic Medicine ◽  
Herbal Drugs ◽  
Diseased Person ◽  
Standard Operating ◽  
Ayurvedic Treatment

Main aim of Ayurveda is to maintain health of healthy person and make free from diseases to diseased person. The aim of Ayurveda is proved by many acharya by applying ayurvedic fundamentals.one of them is ayurvedic medicine. Which plays important role in ayurvedic treatment Acharya focus on preparation of herbal drugs along with the quality of the drug. This drug has an appropriate qualities and significant result on particular diseases.              Kshar is one of the important ayurvedic formulation which is used in various diseases.it has a unique quality than other drugs .it is an alkali preparation of either by single herb or multiple herb.by its unique qualities many kruchha sadhya diseases are treated.               Now a day we see that the ayurvedic formulations are not much effective on the diseases. The cause is many more such as the low efficacy of medicinal plant, wrong method of preparation etc. if we make an ayurvedic formulation according to the ayurvedic text with standard operating procedure by maintaining quality of the drug we can get significant effect on some particular disease.                 In this paper we explain one of the standard procedure of kadalikshar preparation according to sushrut Samhita. Total estimation of how much raw material used, time require to prepare kadalikshar, how much loss of raw drug and material and method of kadalikshar preparation is explained.

scholarly journals Establishment of Standardization Parameters for Herbal Formulation, Swarasa Bhvit Amalaka Churnam

2019 ◽  
Vol 9 (4-A) ◽  
pp. 108-121
Author(s):  
Vihangesh Kumar Dixit ◽  
Raghuveer Irchhaiya ◽  
Nandlal Singh ◽  
Rishikesh Gupta
Keyword(s):  
Human Health ◽  
Human Body ◽  
Phytochemical Screening ◽  
Main Ingredient ◽  
Foreign Matter ◽  
Organoleptic Evaluation ◽  
Herbal Formulation ◽  
Simple Processing ◽  
Herbal Formulations

Herbal formulations are very useful for human health because of their natural and simple processing. A quality herbal formulation must pass the test for their characteristic properties. Inspite of the large number of Ayurvedic formulations are available in the market, standards of their quality are yet to be laid. Amlaka churnam or amalaki rasayanam is a swarasa bhavita, important herbal formulation used for treatment related to immunity systems of human body. In addition to this it is also used for nurturing of skin, heart, eye and stomach. The main ingredient of amalaka churnam is amla (Embalica officinalis) family Euphorbiaceae. Though amalaka churnam is described in many classical Ayurvedic granthas, but there are minor differences in their formulations. Also marketed formulations of amalaki rasayanam by manufacturers do not have description about its standardization.  Therefore, it is necessary to develop standard parameters for establishment of quality of the formulation. In this work, a standardization of herbal formulations of amalaka churnam is reported in terms of organoleptic evaluation of ingredients with rasayana formulation, loss of drying analysis, foreign matter, phytochemical screening, pH estimation, evaluation of ash value, extractive value and rheological evaluation. Keywords: Bhvit, amalaka Churnam, Organoleptic, rheological etc.

scholarly journals Through years, across distances…

2018 ◽  
Vol 14 (3) ◽  
pp. 122-127
Author(s):  
Gregory A. Gerasimov
Keyword(s):  
Medical Profession ◽  
Human Microbiome ◽  
Intestinal Bacteria ◽  
Internal Organs ◽  
Ancient Science ◽  
Intestinal Dysbiosis ◽  
The Usa ◽  
The Times ◽  
Traditional Approaches

Medicine is an ancient science. In the modern sense, the medical profession began to form after bloodletting as a universal way of restoring the balance of bodily juices was replaced by more scientific and less crippling methods. But in medical practice it often happens that new methods of diagnosis and treatment get along with very ancient ones, and some traditional approaches, that previously had no reliable justification, receive solid scientific support. This historic process closely resembles the flow of water in a river: fast in the rapids, slow along the shores and sedentary in quiet creeks, at the bottom of which one can find shabby garbage brought by floods. All this is in a circuit – something disappears in the abyss, and something suddenly floats to the surface. The scandal in the USA with the recall of a medicine made from desiccated and dried porcine thyroid gland reminded us that some concoctions, which have been known since the times of ancient Chinese medicine, and drugs that appeared relatively recently thanks to modern pharmacology can easily coexist in clinical practice. With one essential caveat: the quality of such concoctions should be controlled as carefully as the newest drugs. Modern technologies have allowed us to analyze the genome of the inhabitants of our internal organs, that constitute the human microbiome. This made it possible to rehabilitate the concept of dysbacteriosis (dysbiosis), which was previously considered anti-scientific. For example, intestinal bacteria are able to compete with the host organism for selenium and even capable of aggravating its deficiency, as well as modulating the bioavailability of iodothyronines. It is possible that intestinal dysbiosis may be one of the causes of thyroxine malabsorption. All these and much more in this column “De Gustibus”.

Medicinal Herbs Affecting Gray Hair in Traditional Persian Medicine

2020 ◽  
Vol 06 ◽  
Author(s):  
Mahboobe Raeiszadeh ◽  
Maryam Rameshk ◽  
Shahram Kalantari Khandani
Keyword(s):  
Growth Promotion ◽  
Preventive Treatment ◽  
Traditional Healers ◽  
Hair Dyes ◽  
Gray Hair ◽  
Persian Medicine ◽  
Traditional Persian Medicine ◽  
Hair Care ◽  
Herbal Formulations

Background: With today’s increasing life expectations, the desire to look youthful plays a bigger role than ever before. The use of plants has a history as old as that on mankind himself and in the Traditional Persian Medicine many herbal formulations are reported for hair growth promotion as well as improvement in quality of hair. Objective: The aim of this study is to introduce the effective medicinal plants in Traditional Persian Medicine on graying hair that can be used in new products. Methods: The present study is an overview study and codified by the Library search method in the main sources of Traditional Persian Medicine. Results: After reviewing the selected book, we discovered that three types of formulation recommended for gray hair by traditional healers contain preventive, treatment and dying compounds. Our research indicated that the most frequently parts of the plants used in treatment and preventive compounds are leaves, seeds and fruit that are more used as topical oil or oral compound (electuaries). The majority of plants parts used in hair dyes are leaves, fruit and gum which all are used topically. Conclusion: synthetic based formulations may cause several side effects on human health and the increasing popularity of the herbal drugs in hair care products it is worthwhile to carry out systemic investigation on the efficacy of these formulations and their preparations. We hope this study could show a way of using of Traditional Persian Medicine in hair care products in the future.

Practical view of Yavakshara preparation

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
Avinash Vishnu Bharati Bharati
Keyword(s):  
Standard Procedure ◽  
Standard Operating Procedure ◽  
Healthy Person ◽  
Raw Material ◽  
Ayurvedic Medicine ◽  
Herbal Drugs ◽  
Diseased Person ◽  
Standard Operating ◽  
Ayurvedic Treatment

Main aim of Ayurveda is to maintain heath of healthy person and make free from diseases to diseased person. This aim of Ayurveda is proved by many acharya by applying ayurvedic fundamentals. One of them is ayurvedic medicine. Which plays important role in ayurvedic treatment. Acharya focus on preparation of herbal drugs along with the quality of the drug. This drug has an appropriate qualities and significant result on particular diseases. Kshara is one of important the ayurvedic formulation which is used in various diseases. It has a unique quality than other drugs. It is an alkali preparation of either by single herb or multiple herb. By its unique qualities many kruchhra sadhya diseases are treated. Now a day we see that the ayurvedic formulations are not much effective on the diseases. The causes are many more such as the low efficacy of medicinal plant , wrong method of preparation etc. available market preparation are not much effective and many more products are fail to maintain quality of the drug as per ayurvedic text.  If we make an ayurvedic formulation according to ayurvedic text with standard operating procedure by maintaining quality of the drug we can get significant effects on some particular diseases. In this paper we explain one of the standard procedure of Yavakshara preparation according to Sushrut Samhita. total estimation of how much raw material used, time require to prepare yavakshara, how much loss of raw drug and material and method of yavakshara preparation is explained.

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