scholarly journals SERUM AND TISSUE MUCOPROTEINS AND SIALIC ACID IN THYROID DISEASES

2008 ◽  
Vol 15 (03) ◽  
pp. 309-316
Author(s):  
ZARFAR IQBAL ◽  
TASNEEM ZAFAR
Keyword(s):  
Sialic Acid ◽  
Correlation Coefficient ◽  
Inverse Relationship ◽  
Thyroid Tissue ◽  
Normal Subjects ◽  
Thyroid Diseases ◽  
Pathological State ◽  
Serum Sialic Acid ◽  
Toxic Goiter ◽  
Relationship Of

. Objective: To find the correlation coefficient of serum mucoproteins and sialic acid to thyroid tissuein thyroid diseases. Study Design: The study was carried out at J.P.M.C, Karachi. Materials and Methods: A total oftwenty four thyroid patients and twenty normal subjects were studied. The cases were divided into non toxic goiterfourteen, and toxic goiter ten on the basis of clinical and physical examination, thyroid scanning and hormone analysis.Thyroid hormones were estimated in serum. Mucoproteins and sialic acid were estimated in serum as well as in thyroidtissue. Results: Estimations of thyroid hormones and thyroxine binding globulin (T.B.G.) are useful clinically to evaluatethe functions status and diagnosis of different thyroid disorders. Thyroid tissue is mainly composed of glycoprotein,thyroglobulin, and different studies showed that serum glycoprotein fractions varied in different thyroid diseases.Si 4gnificantly increased levels of T were observed in toxic goiter group. The levels of TBG was significantly increased4in non toxic goiter, toxic goiter patients while T /TBG ratio was significantly decreased in non toxic goiter. Coefficientcorrelation ( r) of serum to tissue mucoproteins shows an inverse relationship in non toxic goiter and toxic goiter patients.In non toxic goiter and toxic goiter patients the serum sialic acid levels to tissue sialic acid levels also shows an inverserelationship. Conclusion: Correlation coefficient analysis showed an inverse relationship of serum mucoproteins andsialic acid to thyroid tissue. It signifies that carbohydrate moieties are increased in the blood when the tissue arehyperactive and in the pathological state. It further concludes that thyrotoxic state might be converted into nodular formeven into cancerous form later on.

scholarly journals NODULAR GOITERS

2006 ◽  
Vol 13 (02) ◽  
pp. 165-174
Author(s):  
ZAFAR IQBAL ◽  
TASNEEM ZAFAR
Keyword(s):  
Correlation Coefficient ◽  
Inverse Relationship ◽  
Direct Relationship ◽  
Nodular Goiter ◽  
Medical Sciences ◽  
Toxic Nodular Goiter ◽  
Tissue Levels ◽  
Toxic Goiter ◽  
Basic Medical ◽  
Glycosylated Proteins

Objective: The purpose of the study was to estimate the levels of amino sugars and glycosylatedproteins in the blood and thyroid tissues of the patients suffering from thyroid disorders. Study design: The study wascarried out at Basic Medical sciences Institute, J.P.M.C. Karachi. Period: From 1990 to 1992. Materials & Methods:Twenty control subjects and 35 thyroid patients (Non toxic goiter = 14, Non toxic nodular goiter = 12 and Toxic nodulargoiter=9) were studied. T4, TBG and T4/TBG ratio, serum and tissue glucose, protein, glycosylated proteins andhexosamine with their correlation coefficient (r) were estimated Results: Significantly raised levels of TBG in non toxicgoiter and toxic nodular goiter while T4/TBG ratio was significantly decreased in non toxic goiter and toxic nodulargoiter. In non toxic goiter patients correlation coefficient analysis showed a direct relationship (serum to tissue levels)of glucose(r=0.47), glycosylated proteins(r=0.40) and hexosamine (r=0.23) while an inverse relationship was found incase of protein(r= -0.38). In non toxic nodular group inverse relationship was only found in proteins (r= -0.48) estimationwhile direct correlation coefficient was observed in glucose (r= 0.29), glycosylated proteins (r=0.13) and in hexosamine(r=0.14). In toxic nodular group hexosamine shows a direct correlation coefficient(r=0.73)while glucose (= -0.53),proteins (r= -0.87)and glycosylated proteins(r= -0.12) have an inverse relationship. Conclusion: It was concluded fromcorrelation coefficient analysis (blood to tissue levels) that in non toxic goiter and non toxic nodular patients glucose,glycosylated protein and hexosamine showed a direct relationship while protein showed an inverse relationship.

ESTIMATION OF SIALIC ACID IN CARDIAC PATIENTS

2008 ◽  
Vol 15 (04) ◽  
pp. 496-499
Author(s):  
TASNEEM ZAFAR ◽  
ZAFAR IQBAL
Keyword(s):  
Sialic Acid ◽  
Total Cholesterol ◽  
Total Lipid ◽  
Dietary Habits ◽  
Hdl Cholesterol ◽  
Normal Subjects ◽  
Cardiac Patients ◽  
The People ◽  
Serum Sialic Acid ◽  
One Year

.Objectives: Lipids are common conjugates of serum lipoproteins while sialic acid is present in combination with lipids andproteins as glycolipids and glycoproteins respectively. This study was aimed to get some preliminary information regarding the possiblecorrelation between serum sialic acid and lipid profile in cardiac patients to investigate the possibility of using these parameters to aid thediagnosis and prognosis. Material and methods: Normal subjects (15) and Cardiac patients (42) were estimated. Total cholesterol , Totallipid, Triglycerides , HDL-C and Serum Sialic acid was measured. Duration and place :One year (Jan-Dec. 2005) at POF Hospital ,Wah Cantt.Results: Total lipids 523.4 ± 136.2 mg/dl, Total Cholesterol 142.7 ± 43.3 mg/dl, Triglyceride 81.5 ± 51.6 mg/dl, HDL-C 25.51 ± 10.3 mg/dl andSialic acid was estimated to be 150.8 ± 41.1 mg/dl in normal subjects, while in cardiac patients (n = 42) the level of total lipid was 747.5 ± 247.8mg/dl, total cholesterol 174.0 ± 43.4 mg/dl, triglyceride 154.5 ± 147.8 mg/dl and HDL-cholesterol was 18.1 ± 10.6 mg/dl while Sialic acid wasestimated to be 216.1 ± 57.0 mg/dl in cardiac patients. Conclusion: Results indicate that all the parameters i.e. total lipid, cholesterol,triglyceride and sialic acid except HDL-cholesterol, studied were significantly higher in cardiac patients (P < 0.01) while HDL-cholesterol wassignificantly lower in these patients (P < 0.01).One possible explanation to this could be the dietary habits of the people of this area who preferto consume vegetable oils which are considered to be rich in polyunsaturated fatty acids, rather than a lower intake of fat rich diet. In additionto this, these people consume substantially large quantities of garlic and onions which again are considered to generate hypocholesterolemiceffects.

Locating Al in the DABCO catalyst before and after Al extraction

1990 ◽  
Vol 48 (4) ◽  
pp. 265-267
Author(s):  
Kathleen B. Reuter
Keyword(s):  
Active Site ◽  
Inverse Relationship ◽  
Transverse Direction ◽  
Reaction Rate ◽  
Acid Phosphate ◽  
Fracture Surfaces ◽  
Al Content ◽  
Before And After ◽  
Relationship Of

The reaction rate and efficiency of piperazine to 1,4-diazabicyclo-octane (DABCO) depends on the Si/Al ratio of the MFI topology catalysts. The Al was shown to be the active site, however, in the Si/Al range of 30-200 the reaction rate increases as the Si/Al ratio increases. The objective of this work was to determine the location and concentration of Al to explain this inverse relationship of Al content with reaction rate.Two silicalite catalysts in the form of 1/16 inch SiO2/Al2O3 bonded extrudates were examined: catalyst A with a Si/Al of 83; and catalyst B, the acid/phosphate Al extracted form of catalyst A, with a Si/Al of 175. Five extrudates from each catalyst were fractured in the transverse direction and particles were obtained from the fracture surfaces near the center of the extrudate diameter. Particles were also obtained from the outside surfaces of five extrudates.

Pengaruh Penghargaan Terhadap Kinerja Karyawan pada CV. Dino Manunggal Karsa Bogor

2019 ◽  
Vol 4 (2) ◽  
pp. 17
Author(s):  
Dedy Mulyadi ◽  
Didik Purwanto
Keyword(s):  
Linear Regression ◽  
Performance Assessment ◽  
Correlation Coefficient ◽  
Linear Regression Analysis ◽  
Strong Relationship ◽  
Simple Linear Regression ◽  
New Employees ◽  
Company Policy ◽  
Effective Manner ◽  
Relationship Of

The question of compensation in addition to sensitive to be driving someone to worl due to an effect on morale and discipline employees. Therefore , any  agency or any organization should be able to provide compensation equal to the workload  to create a workforce that efficient and effective manner can be realized. Amaore than that, the company’s goal to improve performance. Performance assessment is a subjective process that involves human judgments. Thus, performance assessment is very likely wrong and very easily influonced by sources that are not actual, so it must be taken into account and considered reasinable. Frformance appraisals are considered  to meet the target if it has a good impact on new employees who rated their performance. Simple linear regression analysis using SPSS version 12:00 data processing obtained tegression equation Y = 0,487 X 74 + with an explanation of X = award, 74 = constant, 0.487 = coefficient awards, and Y = performance based on simple linear regression equation in case of increase of one unit of the  performance award will be increased 0.487 units. If company policy negates the performance award will remain at a constant rate (74) units . (A) Test results obtained thitung significant constants of (12.574) > t table for (1.960 then reject Ho constanta significant meaning. (B) significant Test award coefficient t count the results obtained by (2.164)> t table foe (1.96) then reject Ho the mean coeffent of appreciation affect the performance . (C) correlation coefficient analysis is done by calculating the product moment corration (pearson)  to test  whether or not a strong  relationship between the variables X  dan Y , based on the results of cakculations with SPSS  table valuse obtained by calculating the  correlation coefficient r (0.3100> r on the table for a = 0,05 (0.291) then reject Ho, which means there is a relationship of respect for performance. When we enter these valuse in the table shows the interpretation of the correlation coefficient between the interval from 0.20 to 0.399 which has a low relationship

THE EFFECT OF ALTERATION OF THYROXINE BINDING CAPACITY ON THE DIALYZABLE AND ABSOLUTE FRACTIONS OF TRIIODOTHYRONINE IN CIRCULATION

1973 ◽  
Vol 72 (2) ◽  
pp. 265-271 ◽  
Author(s):  
J. H. Dussault ◽  
D. A. Fisher ◽  
J. T. Nicoloff ◽  
V. V. Row ◽  
R. Volpe
Keyword(s):  
Correlation Coefficient ◽  
Inverse Relationship ◽  
Binding Capacity ◽  
Hormone Concentration ◽  
Thyroxine Binding Globulin ◽  
Serum Thyroxine ◽  
A Value ◽  
The Mean ◽  
Male Subjects ◽  
Female Subjects

ABSTRACT In order to determine the effect of alterations in binding capacity of thyroxine binding globulin (TBG) on triiodothyronine (T3) metabolism, studies were conducted in 10 patients with idiopathically low (7 subjects) or elevated (3 subjects) TBG levels and 10 subjects given norethandrolone (7 male subjects) or oestrogen (3 female subjects). Measurements of serum thyroxine (T4) concentration, maximal T4 binding capacity, serum T3 concentration and per cent dialyzable T3 were conducted. Serum T3 was measured both by chemical and radioimmunoassay methods. In patients with idiopathically low TBG, the mean serum T4 concentration was low (2.4 μg/100 ml), the mean serum T3 level low (55 ng/100 ml), the mean per cent dialyzable T3 increased (0.52%), and the calculated free T3 concentration normal (186 pg/100 ml). In patients with idiopathically high TBG levels the mean T4 concentration was high (10.3 μg/100 ml), the mean T3 level slightly elevated (127 ng/100 ml), the% dialyzable T3 low (0.10%) and the calculated free T3 concentration low normal (123 pg/100 ml). The correlation coefficient between the per cent dialyzable T3 and maximal TBG binding capacity in the 20 subjects was 0.68, a value significant at the P < 0.01 level. Thus, alterations in binding capacity of TBG seem to influence T3 and T4 metabolism similarly; the inverse relationship between the % of dialyzable hormone and total hormone concentration tends to keep the absolue levels of free hormones stable.

A FORECAST OF PRODUCTIVE LONGEVITY OF HOLSTEIN COWS BY INDIRECT SIGNS

2020 ◽  
Author(s):  
З.С. САНОВА
Keyword(s):  
Correlation Coefficient ◽  
Aging Process ◽  
Direct Relationship ◽  
Stability Index ◽  
Age At First Calving ◽  
Group I ◽  
Predicted Values ◽  
The Stability ◽  
Relationship Of ◽  
The Relationship

В статье представлены материалы о взаимосвязи продолжительности продуктивного использования коров с характеристикой устойчивости к деградации, с возрастом отела и удоем. В исследованной, разнородной по происхождению, группе животных для прогноза продуктивного периода коров, обусловленного устойчивостью к деградации и возрастом первого отела, пригодно уравнение регрессии, аргументами в котором являются индекс устойчивости, возраст первого отела в первой и второй степенях. Коэффициент корреляции межу предсказанными значениями продуктивного периода и его фактическими величинами в I группе составляет 0,502, во II - 0,604. При этом крайние варианты прогнозируются со статистическими ошибками 5 мес при оценке индекса устойчивости по 2 лактациям и 4,1 мес по 3, а средние варианты, соответственно, 1,6 и 1,51 мес. Индекс устойчивости к процессу старения является важной характеристикой биологических особенностей коров, определяющий их продуктивное долголетие. Его оценка по первым 2 и 3 лактациям имеет прямолинейную связь с продуктивным периодом (r=0,4109 и r=0,5270), соответственно. Зависимость продуктивного периода от возраста первого отела криволинейная — с увеличением возраста первого отела сокращается срок продуктивного использования, при возрасте первого отела более 1400 дней срок продуктивного использования колеблется от 1,33 до 1,41 лактации. Коэффициент корреляции между этими характеристиками коров составляет - 0,2164 в I и - 0,2620 во II группах. The article presents materials about the relationship of the duration of productive use of cows with the characteristic of resistance to degradation, with the age of calving and milk yield. In the studied group of animals, which is heterogeneous in origin, the regression equation is suitable for predicting the productive period of cows due to resistance to degradation and the age of the first calving, the arguments of which are the stability index, the age of the first calving in the first and second degrees. The correlation coefficient between the predicted values of the productive period and its actual values in group I is 0.502, in group II - 0.604. At the same time, the extreme variants are predicted with statistical errors of 5 months when evaluating the stability index for 2 lactations and 4.1 months for 3, and the average variants, respectively, are 1.6 and 1.51 months. The index of resistance to the aging process is an important characteristic of the biological characteristics of cows, which determines their productive longevity. Its estimate for the first 2 and 3 lactations has a direct relationship with the productive period (r=0.4109 and r=0.5270), respectively. The dependence of the productive period age at first calving curvilinear with increasing age at first calving reduces the time to productive use, while age at first calving of more than 1400 days, the period of productive use ranges from 1.33 to 1.41 lactation. The correlation coefficient between these characteristics of cows is-0.2164 in I and-0.2620 in II groups.

The Relationship of Root Mean Square Value of Electromyography and Isometric Torque of Quadriceps in Normal Subjects

2016 ◽  
Vol 26 (1) ◽  
pp. 58
Author(s):  
Qiurong XIE ◽  
Zheng JIANG ◽  
Qinglu LUO ◽  
Jie LIANG ◽  
Xiaoling WANG ◽  
...  
Keyword(s):  
Root Mean Square ◽  
Normal Subjects ◽  
Mean Square ◽  
Isometric Torque ◽  
Relationship Of ◽  
The Relationship

Glucose and Adenosine Triphosphate Level in Normal Subjects

1974 ◽  
Vol 125 (588) ◽  
pp. 459-460 ◽  
Author(s):  
J. Damas Mora ◽  
D. Vlissides ◽  
F. A. Jenner
Keyword(s):  
Blood Glucose ◽  
Correlation Coefficient ◽  
Adenosine Triphosphate ◽  
Whole Blood ◽  
Normal Subjects ◽  
Red Cell ◽  
Linus Pauling

In Orthomolecular Psychiatry; Treatment of Schizophrenia, edited by David Hawkins and Linus Pauling (1973), Beebe and Wendel (pp. 278–302) report a high correlation coefficient of r = 0.99 (which we calculate gives N = 42, p very much lower than 0.001) between whole blood glucose and adenosine triphosphate (ATP). This relationship they claim is no longer maintained in schizophrenics with anxiety, r = 0.16 (N = 62, p > 0.1). Erban and Hanzlicek (1966), Hansen (1972) and Hansen and Dimitrakoudi (1974) have suggested a possible significance of whole blood ATP in psychoses, and Naylor, Dick, Dick, Le Poidevin and Whyte (1973) have implicated red cell Na/K ATPases. The mechanisms involved in controlling blood ATP seemed therefore worthy of study especially if they are so dependent on glucose.

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