Study of clinical features of patients with chronic eczema

Author(s):  
L.V. Fomina ◽  
A.M. Dashchuk ◽  
E.I. Dobrzhanska

Objective — s to study the clinical features of chronic eczema (CE) in 96 patients aged 18 to 78 years. Materials and methods. The study was carried out in the city clinical dermatovenerological dispensary No. 5 in Kharkov. All patients gave written informed consent to participate in the study.The majority of them (66.7 %) were between 31 and 50 years old. The duration of dermatosis in 6.3 % of the surveyed persons ranged from 6 months to 1 year, in 33.3 % — from 1 year to 5 years, in 42.7 % — from 5 to 10 years, in 17.7 % — over 10 years. The most frequent causes of exacerbation in 51.1 % were neuropsychiatric trauma and stress, in 15.6 % — dise­ases of internal organs and acute respiratory diseases, in 13.5 % — contact with chemicals. In all patients, dermatosis was recurrent. Most often, the surveyed patients complained of moderate intensity itching (51 %) and severe sleep disturbances (66.7 %). Moderate leukocytosis and accelerated ESR were found in 21.9 % of patients, eosinophilia — in 5.1 %. Results and discussion. 96 patients with chronic eczema aged 18 to 78 years were under observation. The diagnosis of chronic eczema was based on anamnestic data, patients’ complaints of itchy skin of varying intensity, objective examination of the patient, as well as recurrences of dermatosis for more than 1 year. The largest number of patients had dermatosis from 5 to 10 years. Chronic eczema in the observed patients was recurrent. The duration of remission was (4.9 ± 0.2) months. The duration of exacerbation was (6.1 ± 0.2) weeks. To characterize the severity of chronic eczema, a scoring system was used, according to which the average severity was (2.63 ± 0.08) points.According to the degree of skin lesions, the forms of dermatosis were limited and widespread. Patients complained of skin itching of varying intensity: more often itching of moderate intensity, periodic; painful, persistent, with an insurmountable need to scratch; short-term; no itching.Also, patients noted sleep disturbance in the form of difficulty falling asleep, sudden awakening at night and lack of a feeling of rest after waking up in the morning. 39 patients had bad habits (smoking, alcohol abuse).Сlinical analysis of blood revealed moderate leukocytosis, accelerated ESR, eosinophilia, signs of secondary infection. Conclusions. The average age of the patients ranged from 31 to 50 years. All examined patients had recurrent dermatosis. The average degree of its severity was (2.63 ± 0.08) points. Most often, patients complained of moderate intensity itching (51 %) and severe sleep disturbances (66.7 %). In 21.9 % of the examined patients moderate leukocytosis and accelerated ESR were revealed, in 5.1 % — eosinophilia.

2020 ◽  
Vol 63 (8) ◽  
pp. 477-483
Author(s):  
Eun Lee

Sleep disturbances, including not being able to fall asleep easily/difficulty falling asleep, waking up frequently, or waking up too early and being unable to fall asleep again/resume sleep are diagnosed as insomnia if they cause significant disruption to daily life and are not caused by other sleep disorders such as pain or sleep apnea. Although insomnia is not considered a serious life-threatening condition, it has not only a high prevalence rate but also a high recurrence rate and tends to become chronic. Chronic insomnia patients tend to show common behavioral and cognitive patterns, typical of which are worrying about not being able to fall or stay asleep, excessive awakening because of this worry, limiting and reducing daytime activities or attempting to stay in bed for long periods to compensate for lack of sleep. These cognitive and behavioral characteristics are important contributing factors for the continuation of insomnia. To date, the most popular and effective treatment option/approach recommended by experts for insomnia is cognitive behavior therapy (CBT). CBT for insomnia consists of the following three non-pharmaceutical treatment elements: 1) behavioral elements such as stimulus control therapy, sleep restriction therapy, and muscle relaxation, 2) cognitive elements, and 3) educational elements focusing on sleep hygiene. However, there are barriers to insomnia patients receiving this treatment including accessibility and cost, despite the abundance of evidence demonstrating their effectiveness. Recently, online CBT for insomnia has become available as an alternative, and its emergence is providing a solution to the barriers to access.


Author(s):  
Hamna Amin ◽  
Kathy Sexton-Radek

Suicide Ideation & Sleep Quality Sleep disturbances were found to be associated with suicidal idealization (Benert & Joiner, 2007). Serotonin is a neurotransmitter that plays a significant role in sleep regulation and has been identified to be relevant in studies of suicide as well. Serotonin is released when individuals wake up, reduced during sleep, and lowest during REM (rapid eye movement) sleep (Benneditti, Serettti et al, 1999). Hypothesis: Less time on screens before falling asleep will have better sleep quality and higher self esteem. Lower chances of committing suicide. Methods: All participants took a pretest during the informational session and a post test during the debriefing session. The pretest and posttest were contrived of demographic and sleep pattern questions. Both assessments were exactly the same. All participants filled out wake up diaries that contained scales in which they had to rate the quality of their sleep from 1 (poor sleep) to 10 (good sleep). These were filled out for seven days immediately after waking up. Control group= No manipulations Experimental group= 30 minutes without smart screen technology + filling out sleep diaries Sleeping diaries did not include any questions or structure. Participants were encouraged to record whatever was on their minds/how they felt about their days. Conclusion: Increase in negative emotions between day 3 and day 6 of the experiment. - Statistical significance was measured (chi square=15.276**, df=1). - “I miss my phone” and “I don’t know how I am going to do this” appeared several times. - “Nomophobia” is a fear of being unable to communicate through a cellular device or the internet. Future Implications: There is no concrete definition of what “good sleep” is. Participants had different definitions as to what they constituted as “good sleep” For example, good sleep is being able to sleep without any disturbances for eight or more hours. Another definition of good sleep could reiterate the amount of alertness one feels after waking up. Further analysis questions can be made in order to establish a definition.


2021 ◽  
Vol 12 ◽  
Author(s):  
Frederike T. Fellendorf ◽  
Carlo Hamm ◽  
Nina Dalkner ◽  
Martina Platzer ◽  
Matteo C. Sattler ◽  
...  

Background: Sleep disturbances are common early warning signs of an episode of bipolar disorder, and early recognition can favorably impact the illness course. Symptom monitoring via a smartphone app is an inexpensive and feasible method to detect an early indication of changes such as sleep. The study aims were (1) to assess the acceptance of apps and (2) to validate sleeping times measured by the smartphone app UP!.Methods:UP! was used by 22 individuals with bipolar disorder and 23 controls. Participants recorded their time of falling asleep and waking-up using UP! for 3 weeks. Results were compared to a validated accelerometer and the Pittsburgh Sleep Quality Index. Additionally, participants were interviewed regarding early warning signs and their feedback for apps as monitoring tools in bipolar disorder (NCT03275714).Results: With UP!, our study did not find strong reservations concerning data protection or continual smartphone usage. Correlation analysis demonstrates UP! to be a valid tool for measuring falling asleep and waking-up times.Discussion: Individuals with bipolar disorder assessed the measurement of sleep disturbances as an early warning sign with a smartphone as positive. The detection of early signs could change an individual's behavior and strengthen self-management. The study showed that UP! can be used to measure changes in sleep durations accurately. Further investigation of smartphone apps' impact to measure other early signs could significantly contribute to clinical treatment and research in the future through objective, continuous, and individual data collection.


2021 ◽  
Vol 1 (1) ◽  
pp. 05-07
Author(s):  
Salvatore Donald Priviterah ◽  
Lance Klusener

Scabies, a highly contagious parasitic skin infestation, is instigated by Sarcoptes scabiei mite. This study was performed to evaluate the clinical profile and quality of life in patients with scabies. 132 scabies patients of both genders were assessed using the revised Dermatology Life Quality Questionnaire (mDLQI) for scabies. The clinical features were also recorded. Clinical features of itching were seen in 104 patients, night aggravation in 86 and skin lesion in 78 patients. Family history was present in 80 patients, past history in 28 and secondary infection in 30 patients. The difference was significant (P< 0.05). 65% subjects reported not feeling embarrassed, in 63% school work was not at all affected, in 70% playing was not at all affected, 81% were not at all experiencing teasing and in 88% friendship was not at all affected. The difference was significant (P< 0.05). Quality of life was affected in scabies patients. Common clinical features were itching, night aggravation and skin lesions


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 59-59
Author(s):  
Roger Wong

Abstract Recent evidence indicates sleep disturbances increase dementia risk. Despite extensive support for this finding, numerous studies are based on cross-sectional data and no research has examined this relationship using a national sample. The purpose of this study was to analyze how sleep disturbances are associated with dementia risk. This study used eight annual waves (2011-2018) of prospective data from the National Health and Aging Trends Study, a large nationally representative U.S. sample of older adults. At each wave, sleep disturbances were measured as: 1) trouble falling asleep in 30 minutes, 2) trouble falling asleep after waking up early, and 3) taking medication to help sleep. The dependent variable was number of years to a new dementia diagnosis. Multivariate analyses were conducted using the Cox proportional hazards model with survey sampling weights applied for a national sample of 6,800 community-dwelling older adults dementia-free at baseline. After controlling for sociodemographics (age, sex, race, education, etc.) and health (mental health, physical health, chronic disease, etc.), trouble falling asleep in 30 minutes was not associated with dementia risk, (Hazard Ratio [HR]=1.01, p=.98), however, trouble falling asleep after waking up significantly decreased risk (HR=0.40, p&lt;.01), and taking sleep medications significantly increased risk (HR=1.72, p&lt;.01). Our findings suggest mixed evidence on how sleep disturbances are associated with dementia risk, but needing sleep medications may be predictive of elevated dementia risk. Future research should explore pathways or behaviors that may decrease dementia risk among individuals who wake up at night, but have trouble falling back to sleep.


Author(s):  
Ankita ◽  
Mukta ◽  
Shivakumar S. Harti ◽  
Medha Kulkarni

Vridh Awsatha compared with Geriatric Population is the state of “Vata Vridhi” related with various Vatavridhi disorders. The older individuals often suffer from multiple medical problems. Like, osteoarthritis, shortness of breath, congestive heart failure, all can lead to difficulty with sleep initiation and maintenance. Trouble with sleep is strongly correlated with complaints about health and depression. Studies examining the prevalence of sleep disturbances in patients with chronic medical diseases have reported that 31% of arthritis and 66% of chronic pain patients report difficulty falling asleep, while 81% of arthritis, 85% of chronic pain, and 33% of diabetes patients report difficulty staying asleep. In a recent National Sleep Foundation survey of adults aged 65 years and over, those with more medical conditions, including cardiac and pulmonary disease and depression, reported significantly more sleep complaints. Objective: This study has been conducted to evaluate the sleeping and waking time of elderly and Diseases pattern with sleep status. Methodology: Interview based Questionnaire was prepared to know the sleep timings, waking up timings of elderly. 96 subjects of both sex was selected from OPD of AIIA, and nearby place and collected data was analyzed by using odd’s. Conclusion: According to the study the health status is directly affected by the timings of sleeping and waking up i.e. people who wake up early tends to be healthier. So, to add the quality in the end years of life, sleep will be main domain to work upon.


CNS Spectrums ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 32-37
Author(s):  
Mario Miniati ◽  
Laura Palagini ◽  
Alessandra Maglio ◽  
Donatella Marazziti ◽  
Liliana Dell’Osso

Objective.To investigate if sleep disturbances may affect treatment outcomes of patients with panic disorder (PD).Methods.Eighty-five PD outpatients with no Axis I comorbidity for mood disorders completed a baseline assessment (T1) and were evaluated after 3 (T2), 6 (T3) and 12 months (T4), with the Panic Disorder Severity Scale (PDSS) total score as outcome measure during a 12-month naturalistic follow-up. Patients were assessed with the Mood Spectrum Self-Report (MOODS-SR, Lifetime Version), and the PDSS.Results.Forty-three patients (50.5%) met criteria for remission (PDSS<5) and 42 (49.5%) for no remission. In a logistic regression model withremissionas the dependent variable, MOODS-SRsleep disturbanceswas the only determinant for a lower likelihood of PD remission. The items accounting for this result were the following:Repeated difficulty falling asleep(chi-square = 4.4; df = 1;p= 0.036), andRepeatedly waking up in the middle of the night(chi-square = 5.2; df = 1;p= 0.022).Conclusion.Lifetime sleep disturbances would represent a cue of mood spectrum (in absence of overt affective comorbidity) that may impair remission in PD.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A211-A211
Author(s):  
Nyree Riley ◽  
Dana Alhasan ◽  
W Braxton Jackson ◽  
Chandra Jackson

Abstract Introduction Food insecurity may influence sleep through poor mental health (e.g., depression) and immune system suppression. Although prior studies have found food insecurity to be associated with poor sleep, few studies have investigated the food security-sleep association among racially/ethnically diverse participants and with multiple sleep dimensions. Methods Using National Health Interview Survey data, we examined overall, age-, sex/gender-, and racial/ethnic-specific associations between food insecurity and sleep health. Food security was categorized as very low, low, marginal, and high. Sleep duration was categorized as very short (&lt;6 hours), short (&lt;7 hours), recommended (7–9 hours), and long (≥9 hours). Sleep disturbances included trouble falling and staying asleep, insomnia symptoms, waking up feeling unrested, and using sleep medication (all ≥3 days/times in the previous week). Adjusting for sociodemographic characteristics and other confounders, we used Poisson regression with robust variance to estimate prevalence ratios (PRs) and 95% confidence intervals (95% CI) for sleep dimensions by very low, low, and marginal vs. high food security. Results The 177,435 participants’ mean age was 47.2±0.1 years, 52.0% were women, 68.4% were Non-Hispanic (NH)-White. Among individuals reporting very low food security, 75.4% had an annual income of &lt;$35,000 and 60.3% were ≥50 years old. After adjustment, very low vs. high food security was associated with a higher prevalence of very short (PR=2.61 [95%CI: 2.44–2.80]) and short (PR=1.66 [95% CI: 1.60–1.72]) sleep duration. Very low vs. high food security was associated with both trouble falling asleep (PR=2.21 [95% CI: 2.12–2.30]) and trouble staying asleep (PR=1.98 [95% CI: 1.91–2.06]). Very low vs. high food security was associated with higher prevalence of very short sleep duration among Asians (PR=3.64 [95% CI: 2.67–4.97]), Whites (PR=2.73 [95% CI: 2.50–2.99]), Blacks (PR=2.03 [95% CI: 1.80–2.31]), and Hispanic/Latinxs (PR=2.65 [95% CI: 2.30–3.07]). Conclusion Food insecurity was associated with poor sleep in a diverse sample of the US population. Support (if any):


Author(s):  
Hassan Abdullah Shakeel ◽  
Hamza Maqsood ◽  
Asher Ishaq ◽  
Basit Ali ◽  
Humza Hussain ◽  
...  

Background: Insomnia, the most common sleep disorder, is the perception or complaint of inadequate or poor-quality sleep because of one or more of the following conditions: difficulty in falling asleep, frequent waking up during the night with difficulty for returning to sleep, waking up too early in the morning, or unrefreshing sleep. It is the most common sleep related complaint reported in the primary care setting. Medical students are specially at risk of developing insomnia and its consequences. This study evaluates the prevalence and severity of insomnia in medical students in relation to certain socio-demographic factors like age, sex and class of education.Methods: A questionnaire based study was done on 135 medical students of Nishtar Medical University, Multan chosen on basis of random sampling to test the prevalence of insomnia using Athens Insomnia Scale (AIS). Out of these students 75 were males and 60 were females. Students were interviewed to obtain information about age, sex and academic year of education.Results: According to Athens insomniac scale scoring, 55 (40.74%) students were found insomniac while 80 (59.25%) were non-insomniac. Out of 55 insomniac students, 23 (41.81%) were males while 32 (58.18%) were females. Likewise, out of 80 non-insomniac students, 52 (65%) were males while 28 (35%) were females. The prevalence of insomnia in medical students was found to be increased with the increasing age. It was found that the females have more insomnia prevalence as well as more severe signs and symptoms of insomnia. Moreover, final year students tend to show more prevalence and severity of insomnia than their juniors.Conclusions: According to this study, 2 out of every 5 students were insomniac. Demographic comparison showed that the prevalence and severity of insomnia was more in females and final year students. Also, it was increasing side by side with increasing age.


2021 ◽  
Vol 9 ◽  
Author(s):  
Sanna Lokhandwala ◽  
Jennifer F. Holmes ◽  
Gina M. Mason ◽  
Christine W. St. Laurent ◽  
Cassandra Delvey ◽  
...  

Sleep disturbances in early childhood are associated with mood and anxiety disorders. Children also exhibit sleep disruptions, such as nighttime awakenings, nightmares, and difficulties falling asleep, in conjunction with adverse events and stress. Prior studies have examined independently the role of sleep on adaptive processing, as well as the effects of stress on sleep. However, how childhood sleep and children's adaptive behavior (i.e., coping strategies) bidirectionally interact is currently less known. Using a within-subjects design and actigraphy-measured sleep from 16 preschool-aged children (Mage = 56.4 months, SD = 10.8, range: 36–70 months), this study investigated how prior sleep patterns relate to children's coping during a potentially stressful event, the COVID-19 pandemic, and how prior coping skills may influence children's sleep during the pandemic. Children who woke earlier had greater negative expression both before and during the pandemic. During the pandemic, children slept longer and woke later on average compared to before the pandemic. Additionally, for children engaged in at-home learning, sleeping longer was associated with less negative expression. These findings highlight how sleep behaviors and coping strategies are related, and the stability of this relationship under stress.


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